Good move by @US_FDA keeping up with the data. We need a lot more Sotrovimab, the only monoclonal antibody that has efficacy vs Omicron @FT by @kiranstacey
@EricTopol @YoDoctorYo @US_FDA @FT @kiranstacey #Sotrovimab’s the only monoclonal for #Omicron in early viral phase? Okay. Maybe. But isn’t there a rejected #monoclonal worth re-examining for the immunologic disruption phase? A #CCR5 antagonist developed for #HIV that delivered promising results in a trial sub population?
@EricTopol @US_FDA @FT @kiranstacey 3CL inhibitors are ubiquitous
@EricTopol @US_FDA @FT @kiranstacey Why don’t we just variant test!!!!! Why are we playing a guessing game with everything. PCR variant test! Give the Delta people the right nAb monocloncal and give the Omicron people Vir… I don’t get it. Why aren’t we using our tools properly
@EricTopol @US_FDA @FT @kiranstacey Good. Since some places are still pushing a useless cocktail on patients. khn.org/news/article/s…
@EricTopol @US_FDA @FT @kiranstacey What are your thoughts on #fluvoxamine?
@EricTopol @US_FDA @FT @kiranstacey Is the FDA keeping up with the data showing that under-5s are being hospitalized near the same rate of 45-64 year-olds now? Doesn't seem like it, or perhaps they'd push for off-label use. usatoday.com/story/news/hea…
@EricTopol @US_FDA @FT @kiranstacey When the data came in to the NIH last month and the COVID-19 treatment guidelines were updated to reflect that only Sotrovimab (Vir Pharm) and Remdesivir retained their activity against Omicron, the other two were removed from most hospital formularies.
@EricTopol @US_FDA @FT @kiranstacey Don’t understand what the good move is… I had friends with Omicron that received monoclonal treatment in FLorida 3 weeks ago very effectively. Now the FDA removes the monoclonal treatment and approves Remdesivir. Are they trying to let people suffer and die??
@EricTopol @US_FDA @FT @kiranstacey Don't you still have Delta as well?
@EricTopol @US_FDA @FT @kiranstacey Except for the resurgence of Delta, which we already see in several countries. covariants.org/per-country