StressMarq @StressMarq
Antibodies, proteins, kits & small molecules for life sciences. Leading manufacturer of fibrilized & oligomeric proteins for neurodegenerative disease research. stressmarq.com Canada Joined October 2009-
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April is #Parkinson's Awareness Month 🧠🌹 StressMarq is committed to supporting Parkinson's research efforts around the world, through the development and distribution of high-quality reagents. Learn more at bit.ly/2zo1saf & bit.ly/38V0XnE #AlphaSynuclein
Happy #EarthDay! StressMarq is a dedicated manufacturer of monomeric, fibrillar & oligomeric protein constructs for #neurodegenerative disease research, proudly based in beautiful British Columbia. 🌎🍁 Learn more about the StressMarq product portfolio🌱 bit.ly/3JuPQnd
Targeting HSP90 ameliorates nephropathy and atherosclerosis through suppression of NF-κB and STAT signaling pathways in diabetic mice - bit.ly/33tau29
Product Citation: @LifeAtPurdue examined TBI-induced Alzheimer's disease using a lab-on-a-chip model. StressMarq's Anti-Acrolein Antibody (SMC-504, bit.ly/3OreOXF ) was used to identify acrolein as a promoter of Aβ-42 aggregation. Paper 👉 rsc.li/3HIoc5i #AD
Altered expression of VMP1 is observed in #MS and #Parkinson's disease. Zack et al. used StressMarq's Anti-VMP1 Antibody (SPC-680) to characterize the VMP1-associated NLRP3 inflammasome response. SPC-680 👉 bit.ly/4cdKRoe Full paper 📑 bit.ly/4a3uB7r
Jellyfish and Fruit Flies Shed Light on the Origin of Hunger Regulation bit.ly/3UD3GIX
Heat shock protein 90 targets a chaperoned peptide to the static early endosome for efficient cross-presentation by human dendritic cells: bit.ly/3R7BNXW
Structure-guided design of an Hsp90 beta N-terminal isoform-selective inhibitor go.nature.com/2GXU601
AI Pinpoints Parkinson's Subtypes Using Stem Cell Images bit.ly/3OKyKno
Wireless Olfactory Feedback System Enhances VR Experiences bit.ly/43riLki
Product Citation: Using StressMarq's Human αSyn PFFs (SPR-322), Mouse αSyn PFFs (SPR-324) & Monomers (SPR-323), researchers verified GPAT as a modifier of #AlphaSynuclein. SPR-322: bit.ly/2u9YHV2 | SPR-323/4: bit.ly/43VOAmF Paper➡️ bit.ly/3JlpIva
StressMarq's Human #αSyn PFFs (SPR-322) & Mouse αSyn PFFs (SPR-324) & Monomers (SPR-323) were used by @uOttawaBMRI to study genetic & pharmacological inhibition of CDK14, a novel therapeutic approach to treating #Parkinson's disease. See the new blog!🍁 bit.ly/4aYtVQW
April is #Parkinson's Awareness Month 🧠🌹 StressMarq is committed to supporting Parkinson's research efforts around the world, through the development and distribution of high-quality reagents. Learn more at bit.ly/2zo1saf & bit.ly/38V0XnE #AlphaSynuclein
Phosphorylation induced cochaperone unfolding promotes kinase recruitment and client class-specific Hsp90 phosphorylation go.nature.com/2IUZm2a
Sporadic inclusion body myositis (sIBM) is not fully understood. Scientists @TohokuUniPR determined that #ApoE and TMEM8C are upregulated in sIBM, using StressMarq's Anti-Amyloid Antibody (A11) (SPC-506). SPC-506 🔬 bit.ly/48HbvTw Paper 📖 bit.ly/49FMNnK
Artificial Intelligence is Transforming Early Detection of Dementia bit.ly/3NBItfy
Researchers immobilized HSP90 on an ATR (attenuated total reflectance) crystal and investigated structural changes induced by drug-like compounds.The effects of the analyzed inhibitors were determined correctly for all compounds with existing X-ray data: bit.ly/2mDazLj
Today is World #Parkinson's Day! 🌹 StressMarq is a proud manufacturer of bioreagents that assist scientists worldwide in their study of this disease & their contributions to the development of future treaments. Learn more 💭 bit.ly/2zo1saf & bit.ly/38V0XnE
Structural ensemble-based docking simulation and biophysical studies discovered new inhibitors of Hsp90 N-terminal domain go.nature.com/2L4vBN5
New Pill Regulates Appetite by Modulating Ghrelin Release bit.ly/3HrMZL0
Andy Truman PhD @TrumanLab
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8K Followers 2K Following 🌷The leading voice for #Parkinson's in Europe since 1992 🌷Supporting the 1.2m Europeans with #Parkinsons and their families 🌷Founder of #WorldParkinsonsDayMake money easily @0p4AiAn85MufVO8
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33K Followers 295 Following Official channel for Regeneron. We turn science into medicine for people with serious diseases. View our terms of engagement here: https://t.co/EuFDUdQQ5EMaureen McKeague @mmckeague
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2K Followers 3 Following We are a free digital publication dedicated to sharing the latest news, research, and Parkinson's disease patient perspectives.Prof. Feynman @ProfFeynman
1.4M Followers 0 Following A universe of atoms, an atom in the universe. Tribute to the great explainer. Tweets about Science and Wisdom. Portrait by L.V Patten.Researchers in Canada got most of what they were hoping for in the country’s 2024 federal budget, with a big boost in postgraduate pay and more funding for research and scientific infrastructure go.nature.com/4azQ8Ft
Congratulations as very well deserved. @lifesciences_bc
Congratulations to UBC’s Dr. Pieter Cullis on being inducted into the @CdnMedHallFame for his groundbreaking discoveries on #LipidNanoparticles that power mRNA vaccines and next generation therapeutics. 👏
Important changes and welcome increases to student scholarships and postdoctoral fellowships. Looks like Banting and Vanier are going away.
🧠On this #WorldParkinsonsDay let's join hands to amplify awareness, share knowledge, and foster support. Together at AD/PD™, we continue our commitment to advancing research, and treatments, and ultimately improving the lives of those impacted by #Parkinsons.
#とあるフナコシ社員の仕事風景 久しぶり更新! サンディエゴに出張に行った社員から写真をもらいました✨ まずはやっぱり…グルメ😋ナチョスとタコス! タコス自立してる!と思ったら専用のお皿…なのでしょうか?こんなのあるんですね!?😳
Could the brain osmolyte N-acetyl aspartate (NAA) being influencing the aggregation of #Parkinsons-associated α-synuclein? New research a lower concentration of NAA inhibits α-Syn aggregation, whereas higher concentrations of NAA accelerate the aggregation pubs.acs.org/doi/10.1021/ac…
In APOE4/4 microglia, Aβ triggers a triglyceride synthesis enzyme. Then they accumulate lipid droplets and release something neurotoxic. @Stanford ow.ly/JEGU50QSeiJ
Drs. Brian Christie (@BrainbBri) & Sandy Shultz (@shultz_sandy) will use a unique pre-clinical model to research intimate partner violence brain injury thanks to funding from the National Women’s Health Research Initiative @CIHR_IRSC @CIHRIGH @WAGE_FEGC uvic.ca/medsci/news/cu…
Nitrase Therapeutics presented new data at #ADPD2024 meeting on their antibodies targeting nitrated synuclein in preclinical (in vitro & in vivo) models of #Parkinsons; Specific nitrated α-synuclein binding affinity of <2 nM in vitro globenewswire.com/en/news-releas…
I leave Lisbon feeling inspired and grateful for the amazing conversations with brilliant scientists and with some of my personal idols. It was another great @adpdnet conference #ADPD2024 #CureAlzheimers #mitovesicles #mitochondria #MoreThanAPowerhouse
UB-312, an experimental Parkinson's vaccine by Vaxxinity, reduced damaging clumps of the alpha-synuclein protein in treated trial patients. buff.ly/43aATji
The Wellington lab is at #ADPD2024! Come check out some of the presentations and posters by our amazing team
🤩 Auditorium I is packed for the opening ceremony of #ADPD2024! @clemere99
We are thrilled, honoured, & humbled to announce that we are now supported by @ALSCanada @BrainCanada This funding will be critical for developing our research in ALS. Thank you to our collaborators @cvandevelde75 & @maximewc. @WaterlooSci @Lucia_Mengqi uwaterloo.ca/science/news/p…
Today, alongside our partner @BrainCanada, we’re pleased to share our continued efforts to fund progress & innovation in ALS research by announcing the recipients of the 2023 ALS Canada-Brain Canada Discovery Grants, w/ a total investment of $1,350,000: bit.ly/3T3dg7J.
Welcome to #ADPD2024! The conference has officially kicked off, and we're thrilled to be here in #Lisbon with our global community of experts in #neurodegenerative diseases. 🧠 Stay tuned for more updates and insights as we delve into the latest advancements in the field. 🌟
Countdown to #ADPD2024 🧠Come and meet us to explore our research on chaperones and protein aggregation in posters and talk📨 DM to set a meeting for discussions and potential collaborations. See you there! 🇵🇹
We’re just TWO days away from the leading event in neurodegenerative disorders - #ADPD2024! 📅This is the time to explore the scientific program and mark your must-attend sessions for an enriching experience. Plan your schedule in advance: bit.ly/42No1PZ
✈️🧠Heading to @adpdnet in Lisbon? Make sure to check the @alzassociation booth(#29)! #ENDALZ
Pathologic α-Synuclein-NOD2 Interaction and RIPK2 Activation Drives Microglia-Induced Neuroinflammation in Parkinson’s Disease biorxiv.org/content/10.110…
Great work by @bllclayton, @TesarLab, & the team. Such an insightful dive into modulation of astrocyte reactivity. @ScienceLemon92 and I were honored to write the @NatureNeuro N&V on this piece - see rdcu.be/dzXrM. (1/2)
Excited to share that my first postdoc publication is officially out! Combining an astrocyte cellular platform and chemical screening we identified drugs that can suppress the formation of pathological astrocytes and promote neuroprotection. thedaily.case.edu/fixing-rogue-b…