Howard Fillit, MD @a_hfillit
Co-Founder and Chief Science Officer @TheADDF. Geriatrician. Neuroscientist. Philanthropy Executive. #Alzheimers Expert. Opinions are my own. alzdiscovery.org New York, NY Joined April 2014-
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Brilliant panel on the Biology of Aging at #ADPD2024 lead by @niranjanbose featuring @ARUK_SusanK @a_hfillit and our good friends from Dementia Discovery Fund and EQT Life Sciences
Inspiring start of Day 3 at #ADPD2024 with @a_hfillit 🤩 “We need to foster collaboration between the #geroscience and #neuroscience community to advance disease treatment. The ultimate goal is to adopt a precision medicine approach based on each patient's unique biomarkers.”
Today #ADDF Co-Founder and Chief Science Officer @a_hfillit delivered a poignant plenary lecture at #ADPD2024 on why the biology of aging framework will guide the next generation of #Alzheimers drugs as we move towards combination therapy and #precisionmedicine. @adpdnet
Great opportunity to advance biomarker research for Alzheimer's disease!
Great opportunity to advance biomarker research for Alzheimer's disease!
The ADDF is thrilled to announce a new, one-of-a-kind partnership with FINGERS Brain Health Institute around #PrecisionPrevention, which aims to uncover new ways to #prevent & treat #Alzheimers by combining #lifestyle & #therapeutic interventions: bit.ly/3LMGtky
Today at #AAIC23, @EliLillyandCo announced the anti-amyloid #donanemab slows #CognitiveDecline by 35%. @a_hfillit notes this serves as further validation that anti-amyloid therapies will be the first class of several classes of drugs to treat #Alzheimers: bit.ly/3rEdNmc
Today's #FDA approval of #leqembi marked a momentous day in the #Alzheimers field. @a_hfillit notes how this approval will serve as a catalyst for driving further developments and investments in the Alzheimer’s drug pipeline based on the biology of aging: bit.ly/3PLD4oB.
Aging is the leading risk factor for #Alzheimers, so we must leverage #CombinationTherapy to target the many different pathologies based on the biology of aging & #comorbidities that lead to its onset. The truth is, no single drug will effectively treat and/or cure the disease.
Aging is the leading risk factor for #Alzheimers, so we must leverage #CombinationTherapy to target the many different pathologies based on the biology of aging & #comorbidities that lead to its onset. The truth is, no single drug will effectively treat and/or cure the disease.
Today's endorsement of Leqembi from the FDA Advisory Committee is encouraging news, but our goal is to develop multiple novel therapies based on the biology of aging to be used in combination with anti-amyloid therapies to stop Alzheimer's in its tracks
Today's endorsement of Leqembi from the FDA Advisory Committee is encouraging news, but our goal is to develop multiple novel therapies based on the biology of aging to be used in combination with anti-amyloid therapies to stop Alzheimer's in its tracks
I’m excited to share a new $200M gift from the Lauder family will fuel @TheADDF to advance the next generation of drugs based on the #biologyofaging, allowing us to explore the full potential of the pipeline and move the most promising research forward: bit.ly/3G3gNNG
As we enter the, "golden age of drug discovery," as stated in @ginakolata's article, it's important to identify new #biomarkers to reduce the costs of developing drugs for diseases, like #Alzheimers, which enable us to run more rigorous & efficient trials nyti.ms/40CSOxr
Today marks a milestone moment for the #Alzheimers field with the approval of lecanemab, but there remains a pressing need for a new generation of drugs that target a whole host of underlying factors based on our understanding of the biology of aging.
Today marks a milestone moment for the #Alzheimers field with the approval of lecanemab, but there remains a pressing need for a new generation of drugs that target a whole host of underlying factors based on our understanding of the biology of aging.
Today's approval of #lecanemab is an encouraging step toward having the multiple drugs we will need to combine in personalized treatments and address each patient's unique #Alzheimers pathology in order to provide meaningful relief. bit.ly/3XeTUg2
Last week at the #MIHealthSummit, the #ADDF's @a_hfillit joined other thought leaders for a panel on @ARPA_H, sharing innovative and creative solutions to large-scale #health challenges facing society, including #Alzheimers.
While data from #gantenerumab is disappointing for the many patients living with #Alzheimers, the #ADDF remains optimistic about the state of Alzheimer's drug development research. Today's diverse pipeline shows 75% of drugs explore novel targets based on the biology of aging.
While data from #gantenerumab is disappointing for the many patients living with #Alzheimers, the #ADDF remains optimistic about the state of Alzheimer's drug development research. Today's diverse pipeline shows 75% of drugs explore novel targets based on the biology of aging.
Clearing of #amyloid plaques resulting from drugs like #lecanemab has shown modest benefit that by itself may not make a significant difference to patients, reported @dmosbergen of @WSJ: on.wsj.com/3Ev1uNy This is why ADDF supports combination therapies as the path forward.
Amidst news on anti-#amyloid therapies, hope continues to lie in the next generation of #Alzheimers drugs that explore other targets based on the biology of aging. Many of these drugs are in development, with 75% of drugs in the pipeline now targeting non-amyloid pathways.
Amidst news on anti-#amyloid therapies, hope continues to lie in the next generation of #Alzheimers drugs that explore other targets based on the biology of aging. Many of these drugs are in development, with 75% of drugs in the pipeline now targeting non-amyloid pathways.
I feel more optimism now than ever before. As I explained to @davebriggstv, aging is the leading risk factor for #Alzheimers which is why treatments informed by the #BiologyofAging are critical. ADDF support will help these treatments cross the finish line yhoo.it/3DwHGZM
Better #diagnostics mean no one has to live with uncertainty of whether they might have #Alzheimers. As I shared in a recent @nytimes letter to the editor, these tools give us the power and agency "to know or not to know" and are revolutionizing research: nyti.ms/3Rh1Lr0
Interesting article by @RitaRubin highlighting the need to look beyond #amyloid to a more holistic approach for developing #Alzheimers therapies guided by the #BiologyofAging. @TheADDF is laser-focused on cultivating a diverse pipeline bit.ly/3R7uf6o @JAMA_current
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Sudha Seshadri, MD @sudha_md
2K Followers 962 Following Director, Glenn Biggs Institute for Alzheimer’s & Neurodegenerative Diseases and South Texas ADRC, UTH San Antonio, a PI in Neurology Framingham Study, Boston UBrilliant panel on the Biology of Aging at #ADPD2024 lead by @niranjanbose featuring @ARUK_SusanK @a_hfillit and our good friends from Dementia Discovery Fund and EQT Life Sciences
Inspiring start of Day 3 at #ADPD2024 with @a_hfillit 🤩 “We need to foster collaboration between the #geroscience and #neuroscience community to advance disease treatment. The ultimate goal is to adopt a precision medicine approach based on each patient's unique biomarkers.”
Today #ADDF Co-Founder and Chief Science Officer @a_hfillit delivered a poignant plenary lecture at #ADPD2024 on why the biology of aging framework will guide the next generation of #Alzheimers drugs as we move towards combination therapy and #precisionmedicine. @adpdnet
Our friends and partners at Gates Ventures are partnering w/ @NACCData to fund up to 3 proposals (OPEN TO ANYONE) at $250k-$1M, focused on advancing #Alzheimers and related dementias research and discovery through digital innovation! Learn more to apply: bit.ly/3NVGVh9.
The ADDF is thrilled to announce a new, one-of-a-kind partnership with FINGERS Brain Health Institute around #PrecisionPrevention, which aims to uncover new ways to #prevent & treat #Alzheimers by combining #lifestyle & #therapeutic interventions: bit.ly/3LMGtky
Today at #AAIC23, @EliLillyandCo announced the anti-amyloid #donanemab slows #CognitiveDecline by 35%. @a_hfillit notes this serves as further validation that anti-amyloid therapies will be the first class of several classes of drugs to treat #Alzheimers: bit.ly/3rEdNmc
Today's #FDA approval of #leqembi marked a momentous day in the #Alzheimers field. @a_hfillit notes how this approval will serve as a catalyst for driving further developments and investments in the Alzheimer’s drug pipeline based on the biology of aging: bit.ly/3PLD4oB.
The #FDA Advisory Committee voted that anti-amyloid #Leqembi shows clinical benefit in early #Alzheimers disease. Our CSO, @a_hfillit, discusses how the milestone underscores the need to develop the next generation of drugs based on the biology of aging: bit.ly/3MRJ3W0
Today marks another milestone for the #Alzheimers community with the #FDA Advisory Committee endorsing #Leqmebi. According to @a_hfillit, this is a step forward in developing multiple therapies based on the biology of aging that can be used in combination bit.ly/3MRJ3W0
Another reason to have optimism for the future of #Alzheimers treatments, but there is still more work to be done and @a_hfillit is leading the way with a biology of aging approach...
Today marks another milestone for the #Alzheimers community with the #FDA Advisory Committee endorsing #Leqmebi. According to @a_hfillit, this is a step forward in developing multiple therapies based on the biology of aging that can be used in combination bit.ly/3MRJ3W0
Some #puzzles & brain games have the potential to help maintain your brain health, reports @Healthline. The ADDF believes #prevention is key to healthy aging. ADDF's @a_hfillit explains the science behind these games: bit.ly/3j1Vqnx
The accelerated approval of #lecanemab is welcome news for the millions living with #Alzheimers, but we have more to do. Drugs will only be beneficial if the right ones are given to the right patient at the right time, and for that we need new #biomarkers. bit.ly/3XeTUg2
Last week at the #MIHealthSummit, the #ADDF's @a_hfillit joined other thought leaders for a panel on @ARPA_H, sharing innovative and creative solutions to large-scale #health challenges facing society, including #Alzheimers.
Dr. Howard Fillit @a_hfillit, Co-Founder and Chief Science Officer at the Alzheimer's Drug Discovery Fndn @TheADDF, says early diagnosis is key for #Alzheimers treatment and helps clear the path for more to participate in clinical trials. Full interview: chc1.co/Howard-Fillit
Join @margaretflinter and I as we speak with Dr. Howard Fillit, Co-Founder and Chief Science Officer at the Alzheimer's Drug Discovery Foundation about research into Alzheimer's @TheADDF @a_hfillit
Dr. Howard Fillit @a_hfillit, Co-Founder and Chief Science Officer at the Alzheimer's Drug Discovery Fndn @TheADDF, says early diagnosis is key for #Alzheimers treatment and helps clear the path for more to participate in clinical trials. Full interview: chc1.co/Howard-Fillit
Hope for #Alzheimers treatments lies in combination therapy and precision medicine. See the @TheADDF and @a_hfillit's take on today's news from #Gantenerumab...
New data shows #Gantenerumab failed to meet its primary endpoint. While anti-amyloid therapies are a starting point, there is an urgent need to develop a new generation of drugs that target a whole host of underlying #Alzheimers causes. See ADDF statement: bit.ly/3g0YXRE
New data shows #Gantenerumab failed to meet its primary endpoint. While anti-amyloid therapies are a starting point, there is an urgent need to develop a new generation of drugs that target a whole host of underlying #Alzheimers causes. See ADDF statement: bit.ly/3g0YXRE
Join us today by reading a special article where @a_hfillit MD, @TheADDF Co-Founder and Chief Science Officer provides answers to questions on Alzheimer's and research for developing new treatments to prevent and potentially cure age-related dementias. lifeworx.com/posts/alzheime…
ADDF's Co-Founder & CSO @a_hfillit tells why today's robust pipeline of drugs focused on targets informed by the #BiologyofAging make him more hopeful than ever for the state of #Alzheimers research in a Q&A with @LifeWorx for #AlzheimersAwarenessMonth: bit.ly/3Eiwujp
Clearing of #amyloid plaques resulting from drugs like #lecanemab has shown modest benefit that by itself may not make a significant difference to patients, reported @dmosbergen of @WSJ: on.wsj.com/3Ev1uNy This is why ADDF supports combination therapies as the path forward.
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