Chris Katanski @ckatanski
Chicago, IL Joined March 2017-
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Last year this time I was at @UChicago thanks to @EMBOFellows Scientific Exchange Grant. Today I am so excited to say that our work has been published in @NAR_Open !!! Quick thread here! ⬇️🧵 academic.oup.com/nar/advance-ar…
what a fun project to explore the rich data from tRNA sequencing! @UChicagoBMB @SihaoHuang1024
what a fun project to explore the rich data from tRNA sequencing! @UChicagoBMB @SihaoHuang1024
Very excited to announce that our papers describing a translocon that assembles on multipass membrane proteins are now out in @Nature! rdcu.be/cXTjL
Long-read single-molecule RNA structure sequencing using nanopore dlvr.it/SZ5Bv2
Join #IlluminaAccelerator and drive value for your #startup. Apply by October 1, 2022. Now with two locations: San Francisco Bay Area and Cambridge, UK. Apply now: illumina.com/accelerator #IlluminaForStartups
A new paper from Tao Pan's lab Mentioned in the talk at #tRNA2022 conference last week Analysis of queuosine and 2-thio #tRNA modifications by high throughput sequencing academic.oup.com/nar/advance-ar…
tRNA are essential, highly expressed RNAs that remain challenging to study with NGS. A new method from the Pan Lab enables multiplexed tRNA-sequencing to enable quality data from challenging sources: clinical, environment, ocean rdcu.be/cMLLu @NatureComms @UChicagoBMB
Excited to share our findings about the self-assembly of the phage nucleus! In short: it’s primarily composed of a single ~70 kDa protein and forms a beautiful (I may be a little biased 😍) C2 symmetric lattice! biorxiv.org/content/10.110…
A key innovation of mRNA vaccines is the use of pseudoU to evade an innate immune response. Do endogenous genes use this same mechanism? @HuangSihao1024 employs human stool and @nanopore to answer in the Pan lab's new paper genomebiology.biomedcentral.com/articles/10.11… @GenomeBiology @UChicagoBMB
NanoPsu, from @HuangSihao1024, Pan & co, a machine learning approach for detecting pseudouridine in Nanopore native RNA sequencing. The authors use it to show that interferon induces pseudouridine in mRNA in HeLa cells. genomebiology.biomedcentral.com/articles/10.11…
HOLY SHIT I'M ON MARS
#Microbiome characterization by high-throughput transfer RNA sequencing and modification analysis | @NatureComms Communications buff.ly/2EsHDQk #bioinformatics #genomics #tRNA
BioRxiv: Defining the RNA Interactome by Total RNA-Associated Protein Purification dlvr.it/QmRKXH
Excited to announce that we've posted a new preprint on @biorxiv by grad student @ugcgccacc (yes, she actually is going to make you translate that) where we report her remarkable discoveries about cells, heat stress, and intracellular pH. (1/6) biorxiv.org/content/early/…
Celebrating successful talk and poster! #ASCBEMBO17
Msp1 Is a AAA+ Membrane Protein Dislocase for Tail-Anchored Proteins: cell.com/molecular-cell…
What's phase separation of an RNA-binding protein good for? Sensing stress, and surviving it. Our new paper's out! cell.com/cell/fulltext/…
With Preview from Kroschawa & Alberti, "Gel or Die: Phase Separation as a Survival Strategy" cell.com/cell/fulltext/…
Phase separation of PABP (yeast Pab1) under stress is an adaptive response, work by @dallandrummond cell.com/cell/fulltext/…
ShorterLab @ShorterLab
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338 Followers 471 Following Postdoc in the Raj lab at UPenn | Heterogeneity and cell fate in cancer and development | Damon Runyon postdoctoral fellowSingle-read tRNA-seq analysis reveals coordination of tRNA modification and aminoacylation an... ncbi.nlm.nih.gov/pubmed/36537222
Last year this time I was at @UChicago thanks to @EMBOFellows Scientific Exchange Grant. Today I am so excited to say that our work has been published in @NAR_Open !!! Quick thread here! ⬇️🧵 academic.oup.com/nar/advance-ar…
Need to 👀 that one again!!!! @MikeSainristil coming up HUGE for @UMichFootball 😤
Increased levels of eIF2A inhibit translation by sequestering 40S ribosomal subunits bioRxiv biorxiv.org/cgi/content/sh…
yup their budget is still more than mine though
Every BBC series about the universe.
New Research: tRNA abundance, modification and fragmentation in nasopharyngeal swabs as biomarkers for COVID-19 severity: Emerging and re-emerging respiratory viruses can spread rapidly and cause pandemics as demonstrated by the recent severe… frontiersin.org/articles/10.33… #celldevbio
Great Work by @ckatanski ! Very glad to participate in it!
New Research: tRNA abundance, modification and fragmentation in nasopharyngeal swabs as biomarkers for COVID-19 severity: Emerging and re-emerging respiratory viruses can spread rapidly and cause pandemics as demonstrated by the recent severe… frontiersin.org/articles/10.33… #celldevbio
Our papers are out in @Nature! In short: insertion intermediates of multipass membrane proteins recruit factors forming a lipid-filled "pocket" next to Sec61 and allowing insertion of TMDs there, independently of Sec61 lateral gate. N&V on our work: bit.ly/3TxS3kW.
Very excited to announce that our papers describing a translocon that assembles on multipass membrane proteins are now out in @Nature! rdcu.be/cXTjL
Over the summer, the lab has grown quite a bit! We're excited to formally welcome grad students Aidan Flynn, Stephen Plassmeyer, Borna Novak, and Ramiz Somjee (W/ Corbo lab), postdoc Emery Usher, and Cori fellow Jackie Pelham!
Long-read single-molecule RNA structure sequencing using nanopore dlvr.it/SZ5Bv2
Join #IlluminaAccelerator and drive value for your #startup. Apply by October 1, 2022. Now with two locations: San Francisco Bay Area and Cambridge, UK. Apply now: illumina.com/accelerator #IlluminaForStartups
About 10 years ago in a math class, I wondered what ‘eigen’ means in eigenvalues and eigenvectors. Recently I learned that eigentlich means actually in German, and eigen means proper/characteristic. Pretty cool :)
New preprint — and a new (to our knowledge) mechanism by which synonymous codons can regulate gene expression! Looking forward to feedback.
Synonymous codon substitutions regulate transcription and translation of an upstream gene biorxiv.org/cgi/content/sh… #bioRxiv
It's my honor to get the Best Poster Award at the #6thMidwestSingleMoleculeWorkshop! Thanks Yuri Lyubchenko and @unmc for organizing such an inspiring and exciting conference! Also proud to present the work done in @NilsWalterLab and @UMBiophys! Go Blue!
Congrats to our very own @Guoming_Gao @UMBiophys @MichiganChem for winning the only poster award at 6th Midwest Single Molecule Workshop @unmc - what a feat, proud of you! Thanks to Yuri Lyubchenko for organizing!
Our ASAS-SN images are almost as good as #JWST images 😀
Oh, and never take a class taught by me #librarygraffiti latimes.com/archives/blogs…