@devisridhar @gavi A few countries like Australia moved fast to diagnose cases at scale and isolate people who were infected. They were able to limit deaths dramatically. Once the numbers get large in a country it is too late. So the first few months made a lot of difference.

@devisridhar @gavi Also some countries did a better job of reducing mobility, using masks and protecting the elderly. We weren't prepared - no practice in advance.#

@devisridhar @gavi Do you think the world will come together to get ready for the next one? I hope so but I am not sure.#

@BillGates @gavi I'm optimistic about the '100 day challenge'- the idea of sequencing a new genome to developing diagnostics, therapeutics and effective vaccines- and getting them out to people. But requires leadership, planning & foresight. Now is the window to prepare.#

@BillGates @gavi One major problem has been online misinformation on Facebook & other platforms around vaccines, masks and other interventions- how do we deal with this challenge? When expertise is neglected and conspiracy theories are spread as if they are truth?

@devisridhar @gavi Trusted authorities like @WHO and @CDCgov need more resources to see the pandemic early (surveillance) and to communicate better. Social media got behind on trying to get factual information out - there will be a lot of debate about how to do better on that...

@devisridhar @gavi @WHO @CDCgov People like you and I and Tony Fauci have been subject to a lot of misinformation. I didn't expect that. Some of it like me putting chips in arms doesn't make sense to me - why would I want to do that?#

@BillGates @gavi @WHO @CDCgov I'd make a joke but would cause a storm😆. Turning to the Gates Foundation's mission, what do you see as the biggest challenges to development in poor countries now? Have we gone backwards on girls' education & the child survival revolution?

@devisridhar @gavi @WHO @CDCgov From 2000 to the start of the pandemic we made strong progress on health and other goals. The pandemic is a huge setback - including rich countries not focusing on the needs of developing countries as much. I hope we can reverse that.

@devisridhar @gavi @WHO @CDCgov I am optimistic about polio eradication - we are close. Malaria, HIV, Nutrition, will take a lot longer but better tools are coming. Education also needs innovation - it is behind where global health is particularly for girls.#

@BillGates @gavi @WHO @CDCgov So tough question: where do you think SARS-CoV-2 came from? What data do you want to see? And is this information important to preventing future spillovers & pandemics?

@devisridhar @gavi @WHO @CDCgov The data is pretty strong that it came from another species which is true for most pandemics. People will continue to speculate on this and we should make sure labs are careful. There will be future outbreaks coming from other species so we need to invest in being ready. #

@BillGates @gavi @WHO @CDCgov Final question- what everyone wants to know -> how and when will the pandemic be over? Does omicron show that we can ‘live with COVID’? Or are other dangerous variants around the corner in 2022?