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Think about this for a second: There are more coronaviruses in the Wuhan Institute of Virology freezer than in all of Genbank …
Think about this for a second: There are more coronaviruses in the Wuhan Institute of Virology freezer than in all of Genbank …
"I wonder if it gave them pause that exactly the virus they decided to hunt for just a year before has now emerged on WIV’s doorstep — and nowhere else — instead of near its natural habitat 1500 km away."
Under 'Impact', EcoHealth alliance forgot to mention "accidentally cause 20 million deaths and 20 Trillion million dollars damage through accidental lab leak by outsourcing ePPP to Wuhan lab using low biosafety precautions"
Under 'Impact', EcoHealth alliance forgot to mention "accidentally cause 20 million deaths and 20 Trillion million dollars damage through accidental lab leak by outsourcing ePPP to Wuhan lab using low biosafety precautions"
Nor did Holmes mention GX_ZC45-r CoV the unpublished sarbecovirus found contaminating his own datasets mdpi.com/2673-8007/2/4/…
Nor did Holmes mention GX_ZC45-r CoV the unpublished sarbecovirus found contaminating his own datasets mdpi.com/2673-8007/2/4/… https://t.co/kBSwLPSnZq
@DavidBahry @ggronvall @zeynep @alisonannyoung @kprather88 @natashaloder @NateSilver538 @joshrogin @mbw61567742 Holmes also doesn’t mention the sequence contamination data found by @stevenemassey, @quay_dr, @ydeigin, @humblesci that showed an unpublished merbecovirus reverse genetics system. pubmed.ncbi.nlm.nih.gov/36865340/
@maiahibbett @fastlerner @MaraHvistendahl @GOPoversight @HouseCommerce Essentially admitting his original WHO investigation was just performative ("go into the lab and ask questions and go around the facilities") and that they are blocking real investigations of the lab.
Given the strong circumstantial evidence for a lab #OriginOfCovid, we need to investigate and fill the still outstanding gap of knowledge: What happened at the Wuhan Institute of Virology in 2018 and 2019? x.com/ayjchan/status…
Given the strong circumstantial evidence for a lab #OriginOfCovid, we need to investigate and fill the still outstanding gap of knowledge: What happened at the Wuhan Institute of Virology in 2018 and 2019? x.com/ayjchan/status…
Since the start of the pandemic, some scientists have repeatedly misled or withheld key info from the public on #OriginOfCovid Even the chief editor of Science said he had argued against lab leak while unaware of circumstantial evidence that was only obtained by FOIA recently.
@jh336405 @Ayjchan Stoyan & Chiu: Worobey spatial stats methods were weird, invalid pubpeer: fixing math and coding errors shifts Pekar odds from 60/1 to less than 0.6/1. (Not a typo!) My JRSSA: arxiv.org/abs/2401.08680 + talk: docs.google.com/presentation/d…
Chilled Virology by Simon Wain-Hobson On reading A flu virus risk worth taking, by Anthony Fauci, Gary Nabel and Francis Collins, Washington Post, December 30, 2011. biosafetynow.substack.com/p/chilled-viro…
Yesterday @Nature dismissed an artificial origin of SC2 in 2 words- without evidence. That's because they won't publish any. But they do publish fraud from WIV and the PLA. @stevenemassey adds to a pile of evidence against WIV's RaTG13. He cites 6 unpublished papers refuting it.
Yesterday @Nature dismissed an artificial origin of SC2 in 2 words- without evidence. That's because they won't publish any. But they do publish fraud from WIV and the PLA. @stevenemassey adds to a pile of evidence against WIV's RaTG13. He cites 6 unpublished papers refuting it.
Great 🧵 on two highly misleading papers
@elonmusk @AlexBerenson why not set up a COVID origins conference @elonmusk? I know many of the best scientists that helped uncover the true SARS2 origin. Evidence suggests this was neither the first independentsciencenews.org/health/did-wes… nor the last x.com/VBruttel/statu… severe lab accident since 2010... rt/♥️ 🙏
@elonmusk @AlexBerenson why not set up a COVID origins conference @elonmusk? I know many of the best scientists that helped uncover the true SARS2 origin. Evidence suggests this was neither the first independentsciencenews.org/health/did-wes… nor the last x.com/VBruttel/statu… severe lab accident since 2010... rt/♥️ 🙏
@abhishek_s_1 @slatestarcodex DEFUSE-type experiments never done? Not independently verified No closer viruses at the WIV? Not independently verified All WIV workers negative for antibodies? Not independently verified (and very implausible) No earlier cases? Not independently verified
@abhishek_s_1 @slatestarcodex Everyone is entitled to their opinion, but not their own facts. It's public record that the WHO had to report on China's assurances only, without access to independent verification, that these suspected cases were all something else.
@abhishek_s_1 @slatestarcodex How uninformed does one need to be to think that China allowed the WHO to “scour” hospital records looking for COVID cases? Even the mainstream media acknowledged that the WHO report’s information was produced entirely by China with no independent review of original info by WHO.
Perlman projects since SARS1 led to SARS2, MERS1 will lead to MERS2 Agree: zoonotic SARS1 was 10,000X less lethal than synthetic SARS2 What could synthetic, 30% lethal, MERS2 do? Anticipating a MERS-like coronavirus as a potential pandemic threat thelancet.com/journals/lance…
@kprather88 @VeeZeeToronto Airborne and Covid origins are intimately tied, and the reason why this got out of control. Gain of Function research without airborne precautions in a BSL-2 setting was a disaster waiting to happen. Kudos to you for calling this out; hopefully it will prevent future similar…
Richard H. Ebright @R_H_Ebright
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442K Followers 3K Following Foreign Correspondent: @FoxNews #FreeEvanGershkovich@MJnanostretch Nobody says it's impossible. F. Wu, arguing that it happens easily in nature, actually comes up with a rate of 0.15%. Does anybody think, given the FOIA'd plans, that the lab probability was that low?ncbi.nlm.nih.gov/pmc/articles/P… As we've discussed, you at times seem averse to numbers.
@MJnanostretch I'm not sure I'd use the phrase "smoking gun". The RE sites are special, however, in being orthogonal to natural fitness while directly relevant to lab fitness. So there's an appreciable factor here for generic Z vs L odds for all Z scenarios.
@MJnanostretch P(6,<8k|ZW) is in (0.0015,0.028). Based on DEFUSE draft, P(6,<8k|ZW) >0.1. That conservative estimate may not be extreme, but there's no way it's a draw.
@tony_vandongen there are more coronavirus species in that freezer than in the rest of China.
Think about this for a second: There are more coronaviruses in the Wuhan Institute of Virology freezer than in all of Genbank …
Zoonatics: “SARS2 didn’t come from WIV, because they didn’t have that backbone”. Daszak: "We have 15,000 samples in freezers in Wuhan and could do the full genomes of 700+ CoVs we've identified"
April 23 2020 FBI responding to tip that reverse genetic clone viruses created as described by NIAID grant "would leave no signatures of purposeful human manipulation" This is after PO 'ruled out' a "purposefully manipulated virus." judicialwatch.org/documents/fbi-… From @JudicialWatch
@harryetaylor @BiophysicsFL @JudicialWatch Dr. Taylor thanks for helping us understand how the COVID-19 pandemic started. Would you be willing to share what you think 'novel viruses' means in the Aim 3 sentence..."test this hypothesis by asking whether novel viruses encoding spike proteins with the highest receptor"...
@humblesci I don't think that was a planned impact. Despite the fact that it was--as predicted already in 2015. and as understood by any informed person lacking a conflict of interest--the most plausible impact.
7/ SARS2’s spike is 23% and 24% different from SCH014/WIV1 and SARS1 respectively. BANAL strains are 22% and 23%. But in terms of human ACE2 binding, the RBD of SARS2-like strains is even better than SARS1, which would have been apparent even from computer modeling.
6/ They were now proposing to sample 5,000 bats in an attempt to “almost fully characterize the expected natural diversity of SARSr- and other β-CoVs in the region”. Their new focus on a particular subset of SARS-like strains was clear:
5/ As the DEFUSE grant proposal was not funded, parts of it made it to EcoHealth’s November 2018 grant renewal application for their NIH grant R01AI110964, joint with WIV, previously active for 2014-2019.
4/ Initially, in March 2018, EcoHealth and WIV pitched a $14M DARPA grant to sample bats in Yunnan caves for SARS-like viruses, and then "DEFUSE" them using "novel chimeric polyvalent recombinant spike proteins" (emphasis added by me):
3/ Moreover, as I will show below, precisely because SARS2 or its BANAL-like progenitor could evade SARS1-based vaccines and antibodies, such strains would have been prioritized and likely turned into full-genome synthetic backbones.
2/ In 2018, WIV started looking for SARS-like viruses that were 10–25% different from SARS1 in their spike but could still enter human cells, and escape SARS1-based antibodies. SARS2 fits those criteria like a glove.
4 years after my first Medium article on Covid origins, I wrote another one. In it, I make the case that SARS-CoV-2 is precisely the virus WIV was hunting for in 2019. yurideigin.medium.com/sars-cov-2-is-… Below is a thread on the key points:
Here is @EcoHealthNYC's slide. Among other things, they intended to use humanized lab animal models and non-human primates. (h/t @capitolsheila)
@gtuckerkellogg @MJnanostretch A plethora of evidence shows that it didn't begin at the wet market, and that the WIV had collected similar viruses and was engaged in risky experiments with them A plethora of circumstantial evidence indicates the most parsimonious explanation is a lab leak
@DavidBahry @ggronvall @zeynep @alisonannyoung @kprather88 @natashaloder @NateSilver538 @joshrogin @mbw61567742 Holmes also doesn’t mention the sequence contamination data found by @stevenemassey, @quay_dr, @ydeigin, @humblesci that showed an unpublished merbecovirus reverse genetics system. pubmed.ncbi.nlm.nih.gov/36865340/