Mark McCarthy @markmccarthyoxf
Using human genetics to advance knowledge & find new therapies. Otherwise: Liverpool FC, cricket, cinema, seafood, travel. Now at Genentech but views mine. Menlo Park, CA Joined June 2009-
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"how geneticists construe human genetic populations... [is] also sociopolitical. Genetic distinctions between human populations are not natural; they are the consequences of categorizations developed by geneticists" 🔥
"how geneticists construe human genetic populations... [is] also sociopolitical. Genetic distinctions between human populations are not natural; they are the consequences of categorizations developed by geneticists" 🔥
@mathiesoniain Weird outcome where the only ancestry visualizations of AoU (as far as I'm aware) are the above UMAP or the below PCA plot where hard genetic clusters are, for some reason, labeled as ethnicities
UMAP aside, I think there is tremendous ambiguity in the use and definition of race, ancestry, and ethnicity throughout the AllOfUs paper (not to mention conflation of genetic ancestry and genetic similarity)
Couldn't agree more! Nothing wrong with PCA.
We are proud to announce that our facilities are fully open to provide genomics sequencing services with no profit motive in Africa! Our objective is to help to advance scientific research, biotech, vaccine, therapy and diagnostics development - A short 🧵 ceri.org.za/news/?token=725
@day156324 I, too, am determined to do the very least I can....
When I thought I was done with the GWAS stories of 2023 and I should wrap up, @StephenORahilly dropped yet another great paper from his team. How can I resist? It's storytelling time. In this hot-off-the-press Nature paper, @DrFejzo et al. uncover an absolutely fascinating…
When I thought I was done with the GWAS stories of 2023 and I should wrap up, @StephenORahilly dropped yet another great paper from his team. How can I resist? It's storytelling time. In this hot-off-the-press Nature paper, @DrFejzo et al. uncover an absolutely fascinating… https://t.co/qX4UZMJqJk
@OpenTargets This will give a trajectory for each of us through health, and from that help patients and doctors make decisions for the future
@OpenTargets The future of common disease might involve better diagnosis, but I think it is hard yards with *just* genetics; rather a whole host of genome wide assays - metabolomics, proteomics, RNAseq on blood, classic blood biochemistry and germline genetics will combine in AI schemes
Fantastic session on the important topic of Precision Prevention in Health: The Power of Genomics @Falling_Walls in Berlin with a constellation of panellists @NancyGenetics @nicolablackwood @markmccarthyoxf @SFatumo and David Crosby. Thank you for the inspirational discussion!
Such an excellent opportunity to speak about how genomics can power precision prevention across global populations @Falling_Walls Science Summit in Berlin today. It was indeed a privilege to brainstorm in a panel with @EleZeggini @nicolablackwood @markmccarthyoxf @NancyGenetics
This is very good. The best articulation I’ve heard.
@dermitzakis @markmccarthyoxf @SlavePetrovski @JoHowson @melrose4747 Room 143AB at 1530-1630 on Friday. Get there early to be assured of the very best coffee and snacks that the convention centre catering team has to offer.
Imagine tweeting this from a private jet in a cost of living crisis when you've literally just cancelled the high-speed train line to the city you've been in. What sort of monstrous lack of awareness is going on?
Imagine tweeting this from a private jet in a cost of living crisis when you've literally just cancelled the high-speed train line to the city you've been in. What sort of monstrous lack of awareness is going on?
Govt reveals first details of ‘Network North’, with regular services running between Oxford, Luton and Colchester.
There is absolutely no possibility that selection bias or reporting tendency consequent on situation could influence this pattern 😐 that’s why causal inference depends on merely totalling observable events 😃
There is absolutely no possibility that selection bias or reporting tendency consequent on situation could influence this pattern 😐 that’s why causal inference depends on merely totalling observable events 😃
One great things about living in the Bay Area is that your favorite bands show up at some point (& usually play some micro venue). Tonight, the metronomic, hypnotic, souly funky jazzy kraftwerky groove of Melbourne’s finest (actually 2nd finest, given @nickcave), Surprise Chef.
Really important thread from @GenomeNathan about RFK Jr's latest idiocy
Really important thread from @GenomeNathan about RFK Jr's latest idiocy
Veera Rajagopal @doctorveera
17K Followers 4K Following MBBS, MD, PhD | GWAS storyteller | Scientist at Regeneron | Human genetics & drug discovery in Neuroscience & Psychiatry | He/HimCecilia Lindgren @ceclindgren
8K Followers 998 Following Director of Oxford Big Data Institute. Proud mom of 3. Co-chair of @icdabio. Wellcome Trust Investigator. Promoting equality in academia. Love 🦈. #🕷🕸💙Daniel J Drucker @DanielJDrucker
29K Followers 1K Following A clinician scientist at LTRI @sinaihealth @uoft @uoftmedicine who studies peptide hormones, GLP-1, diabetes, obesity and the gut endocrine system 🇨🇦🇮🇱Anna Gloyn @annagloyn
4K Followers 762 Following Prof of Pediatrics & Genetics 🧬 - Translational Genomics of Diabetes Lab #diabetes, #genetics #islets #womeninStem #teamscienceAnshul Kundaje (anshu.. @anshulkundaje
22K Followers 2K Following Genomics, Machine Learning, Statistics, Big Data and Football (Soccer, GGMU). Post: @anshulkundaje, Threads: anshulkundajeEric Fauman @Eric_Fauman
6K Followers 246 Following GWAS whisperer 'Nothing in biology makes sense except in the light of evolution' -Dobzhansky DMs open Executive Director, Integrative Biology @PfizerPradeep Natarajan @pnatarajanmd
22K Followers 814 Following Dir of Preventive Cardiology @MassGeneralNews | Assoc Dir of Personalized Medicine @MassGenBrigham | Assoc Prof @harvardmed | Assoc Mem @broadinstituteEwan Birney @ewanbirney
50K Followers 2K Following Deputy Director General of EMBL, Director of EMBL-EBI. I have an insatiable love of biology. @[email protected]. I also work with ONT, Dovetail + GeL.Manolis Kellis @manoliskellis
25K Followers 4K Following Dissecting disease mechanism. Single-cell, Epigenomics, Regulatory Genomics, Disease Genetics, Brain, Cancer, Metabolism. @MIT Prof, @MIT_CSAIL, @BroadInstituteAdam Butterworth @aidanbutty
2K Followers 2K Following Professor of Molecular Epidemiology @CAMBRIDGE_CEU @Cambridge_Uni. Tweeting in a personal capacity.Mike Inouye @minouye271
7K Followers 450 Following Computational biologist. Geriatric millennial. American Australian. Professor @Cambridge_Uni. Director of Data Sciences @BakerResearchAu. Director @CamBakerSGI.Abdel Abdellaoui @dr_appie
9K Followers 2K Following Complex Trait Genetics | Population Genetics | Evolutionary Genetics | @AmsterdamUMC | @UvA_AmsterdamAndrea ganna @andganna
3K Followers 602 Following Associate Prof in health data science @HiLIFE_helsinki @FIMM_UH - MGH/Harvard - Playing with all kind of data - https://t.co/BffgAbQTlsKarsten Suhre @ksuhre
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7K Followers 288 Following Physician-scientist interested in the causes and adverse consequences of obesity. Director MRC Metabolic Diseases Unit, University of Cambridge. Views mine.Jim Johnson, PhD @JimJohnsonSci
13K Followers 8K Following Physiologist, Mentor, Assoc. Director VCHRI, IPTN cofounder, exPharmaVP (NNRCO), Dad, Hub, HockeyGuy. Views≠employer's RT≠endorse he/him/ On all the sites.brent richards @BrentRichards19
2K Followers 486 Following I'm a doctor and scientist trying to use human genetics to help my patients.Michael Love @mikelove
18K Followers 5K Following I'm not on twitter anymore, find my on Bluesky or MastodonMichael Hoffman @mich.. @michaelhoffman
23K Followers 7K Following Chair, Comp Bio & Medicine Program, Princess Margaret Cancer Centre. Assoc Prof, Med Biophysics & Comp Sci, University of Toronto. COI https://t.co/CvupKNIjZr5 Prime Sciences @5PrimeSciences
65 Followers 35 Following We use human genetics to accelerate your drug development programBruce Tao @BruceTao_1999
14 Followers 310 FollowingThomas Edsall @Edsall
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0 Followers 2K FollowingMarcelo Nobrega @nobrega45614375
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95 Followers 84 FollowingH Kian 🤓 @kian_by4743
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2K Followers 2K Following PhD in genetics. MSc in Statistics. Human geneticist. Biostatistician. Martial Artist. My opinions are my own.Muhammad Shoaib @Muhamma51714245
78 Followers 296 Following Postdoctoral Fellow at the Hospital for Sick Children, Univ. of Toronto Interested in Polygenic risk scores, G×E interactions, Statistical genetics, AIJC Grenier, M.Sc @j_c_grenier
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2 Followers 96 FollowingMarkus Rottmann @MarkusRottmann_
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19 Followers 82 FollowingGiulia Rathmes @GRathmes
18 Followers 157 Following MD. Oxford MPH. Internal Medicine Resident. Global Health Advocate.Áine Duffy @Aine_duffy94
68 Followers 96 Following 📍New York City | Irish 🇮🇪| PhD student @IcahnMountSinaiwhatroughbeast @whatroughbeast1
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4 Followers 29 FollowingMegan Dennis @meganydennis
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48 Followers 115 Following PhD candidate | University of Hong Kong | PhD Mum | Mendelian randomizationJakob Woerner @jakob_woerner
107 Followers 208 Following Genomics and Computational Biology PhD Student at UPenn 🧬Lea Urpa @leaurpa
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14 Followers 53 FollowingDr. Nyasha Chambwe @doc_nyasha
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16 Followers 74 FollowingVeera Rajagopal @doctorveera
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8K Followers 998 Following Director of Oxford Big Data Institute. Proud mom of 3. Co-chair of @icdabio. Wellcome Trust Investigator. Promoting equality in academia. Love 🦈. #🕷🕸💙Daniel J Drucker @DanielJDrucker
29K Followers 1K Following A clinician scientist at LTRI @sinaihealth @uoft @uoftmedicine who studies peptide hormones, GLP-1, diabetes, obesity and the gut endocrine system 🇨🇦🇮🇱Anna Gloyn @annagloyn
4K Followers 762 Following Prof of Pediatrics & Genetics 🧬 - Translational Genomics of Diabetes Lab #diabetes, #genetics #islets #womeninStem #teamscienceAnshul Kundaje (anshu.. @anshulkundaje
22K Followers 2K Following Genomics, Machine Learning, Statistics, Big Data and Football (Soccer, GGMU). Post: @anshulkundaje, Threads: anshulkundajeEric Fauman @Eric_Fauman
6K Followers 246 Following GWAS whisperer 'Nothing in biology makes sense except in the light of evolution' -Dobzhansky DMs open Executive Director, Integrative Biology @PfizerPradeep Natarajan @pnatarajanmd
22K Followers 814 Following Dir of Preventive Cardiology @MassGeneralNews | Assoc Dir of Personalized Medicine @MassGenBrigham | Assoc Prof @harvardmed | Assoc Mem @broadinstituteEwan Birney @ewanbirney
50K Followers 2K Following Deputy Director General of EMBL, Director of EMBL-EBI. I have an insatiable love of biology. @[email protected]. I also work with ONT, Dovetail + GeL.Manolis Kellis @manoliskellis
25K Followers 4K Following Dissecting disease mechanism. Single-cell, Epigenomics, Regulatory Genomics, Disease Genetics, Brain, Cancer, Metabolism. @MIT Prof, @MIT_CSAIL, @BroadInstituteAdam Butterworth @aidanbutty
2K Followers 2K Following Professor of Molecular Epidemiology @CAMBRIDGE_CEU @Cambridge_Uni. Tweeting in a personal capacity.Mike Inouye @minouye271
7K Followers 450 Following Computational biologist. Geriatric millennial. American Australian. Professor @Cambridge_Uni. Director of Data Sciences @BakerResearchAu. Director @CamBakerSGI.Andrea ganna @andganna
3K Followers 602 Following Associate Prof in health data science @HiLIFE_helsinki @FIMM_UH - MGH/Harvard - Playing with all kind of data - https://t.co/BffgAbQTlsKarsten Suhre @ksuhre
3K Followers 1K Following Passionate about #GWAS #Metabolomics #Proteomics #Glycomics #Epigenomics, Professor @WeillCornell Medicine - Qatar, Blog on https://t.co/euxyT3LAlf, https://t.co/ViXldJpG3Xstephen o'rahilly (it.. @StephenORahilly
7K Followers 288 Following Physician-scientist interested in the causes and adverse consequences of obesity. Director MRC Metabolic Diseases Unit, University of Cambridge. Views mine.Fabian Theis @fabian_theis
29K Followers 446 Following Computational biologist @HelmholtzMunich, prof @TU_Muenchen & associate PI @sangerinstitute. Dad of 4 and mountain lover. Department news, see @CompHealthMucJim Johnson, PhD @JimJohnsonSci
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2K Followers 486 Following I'm a doctor and scientist trying to use human genetics to help my patients.Michael Hoffman @mich.. @michaelhoffman
23K Followers 7K Following Chair, Comp Bio & Medicine Program, Princess Margaret Cancer Centre. Assoc Prof, Med Biophysics & Comp Sci, University of Toronto. COI https://t.co/CvupKNIjZrHilary Martin @hilsomartin
2K Followers 390 Following Group Leader in Human Genetics at the Wellcome Sanger Institute. College Research Associate at St John's College, Cambridge.Timothy Snyder @TimothyDSnyder
553K Followers 58 Following Levin Professor of History at Yale. Author of "On Freedom," "On Tyranny," "Our Malady," "Road to Unfreedom," "Black Earth," and "Bloodlands"Nabihah Iqbal @nabihahiqbal
8K Followers 768 Following MUSIC LOVER / MUSIC MAKER ❤️🎵🙏🏽📻🎸❤️ Contact: [email protected]Avantika Lal @lal_avantika
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13 Followers 46 Following Microbiome, Systems Biology, Multi-omics data integration and MOREMo Lotfollahi @mo_lotfollahi
6K Followers 1K Following I train neural networks and dogs to do cool things! ML for biology and drug discovery| Faculty @sangerinstitute.Sasha Gusev @SashaGusevPosts
8K Followers 3K Following Statistical geneticist. Associate Prof at @DanaFarber | @harvardmed | @DFCIPopSciAlokkumar Jha @KnowingAlok
307 Followers 256 Following Assistant Professor of Research in Neuroscience @WeillCornell #datascience #genetics #computational biology opinions are my own.Avtar Singh @avtar00_singh
670 Followers 2K Following principal scientist @genentech | genomics | microscopy | biophysicsSegun Fatumo @SFatumo
4K Followers 918 Following Associate Professor, NCDE, LSHTM, United Kingdom. Associate Professor, MRC/UVRI and LSHTM Uganda. Genomics | GWAS | Africa | Capacity Building | Global HealthRobert Peston @Peston
1.4M Followers 2K Following ITV (pol ed), Speakers for Schools (founder), writer (WTF), Hospice UK (vice pres), Arsenal (East Stand), Peston (as in #Peston show, 10.45pm Weds). So?Nicholas Katsanis @NicholasKatsan1
2K Followers 2K Following Author of lit fiction, student of the human condition. Views are my own quirkiness I picked up traveling. Words: @LiterallyStory, @DelmarvaTh, @PenumbricMag, ++Paul H HODSON @PaulHHodson
6K Followers 6K Following Interested in decarbonisation, cities and how politics and the economy work. Also board games. Living in London again after 30 years. RT≠endorsement.Rory Stewart @RoryStewartUK
564K Followers 1K Following Brady-Johnson Professor Grand Strategy, Jackson/Yale. Author PoliticsOnTheEdge. @Restispolitics podcast w Alastair Campbell. Senior Adviser @GiveDirectly.The News Agents @TheNewsAgents
141K Followers 11 Following Lifting the curtain on the biggest stories in the UK, U.S. and beyond. With @Maitlis, @JonSopel and @Lewis_Goodall. 🎧 Listen and subscribe on @GlobalPlayer 📲John Burn-Murdoch @jburnmurdoch
491K Followers 6K Following Columnist and chief data reporter @FinancialTimes | Stories, stats & scatterplots | Senior fellow @LSEdataScience | [email protected]Arab Strap @ArabStrapBand
8K Followers 64 Following “The Proclaimers from Hell.” New album Out 10 May on Rock Action Records. Pre Order Now.Michelle Trenkmann @MT_Genetics
2K Followers 265 Following Love science. Senior Editor @Nature, previously @NatureComms. If it's not science, I'll probably be in the gym or the kitchen (also science). All views my own.Burstein lab @BursteinLab
523 Followers 277 Following Having fun with microbial genomic and machine learning @TelAvivUniRosie Holt @RosieisaHolt
305K Followers 3K Following See me on stage! https://t.co/48MElLDOpd • I’ve a POD https://t.co/4QtF1s4A6N • Buy me ☕️: https://t.co/RVOCBrYEbj • Rep: @schapmantalentnevboard @nevboard
345 Followers 286 Following All opinions are my own. Just standing on the shoulders of giants to show improvements in health care and patient safety, and hopefully to prisoner healthProf Rachel Batterham @ProfBatterhamMD
4K Followers 419 Following I am Professor of Obesity, Diabetes & Endocrinology at University College London. I am passionate about improving the health of people living with obesity.Adem yesuf @Ademyesuf
88 Followers 183 Following Genetic epidemiologist with particular interest in pharmacogenomicsAlexander Strudwick Y.. @AlexTISYoung
4K Followers 2K Following Statistical geneticist @ UCLA & part of the SSGAC. Oxford PhD. Research how we can use family data to disentangle nature and nurture. Methods developer.Patsy Munroe @munroe_patsy
567 Followers 1K Following Professor at QMUL, Cardiovascular Geneticist and avid Liverpool FC fanDr Ronald Ma @DrRonaldMa1
860 Followers 701 Following diabetes researcher and clinician, #endocrinology #diabetes, #gestational diabetes, #diabetes in Asia, #PCOS, diabetes advocacy, #NCD, #genomics Views my ownCarl Heneghan @carlheneghan
102K Followers 897 Following Prof of EBM, Director @CebmOxford, NHS Urgent Care Doc. Updates at https://t.co/jBw5SmMxigJulie Tuck @JulieTuck17
4 Followers 60 FollowingDanny Chou @DannyHChou
1K Followers 1K Following Assistant Professor of Pediatrics Endocrinology & by courtesy of Chemical & Systems Biology, Stanford UniversityDavid Ochoa @d0choa
1K Followers 1K Following Drug discovery | Computational Biology | Human Disease Genetics | ML | Cloud computing - @opentargets - @emblebiTim McDonald @T_J_McDonald
426 Followers 404 Following Consultant biochemist, Head of Blood Sciences at RD&E and NIHR researcher #ExeterDiabetes #exeter_labDamian Smedley @SmedleyDamian
53 Followers 22 FollowingJesMaimaris @JMaimaris
173 Followers 836 Following Genomics, Immunology, Paediatrics, Rare Diseases. NIHR Clinical Lecturer @iit_ucl Burns/Morris Lab. Clinical Fellow on Topol ReviewNikos Panousis @npanousis
441 Followers 436 Following Scientific Investigator-Computational Biology @GSK. Former Postdoctoral fellow at @sangerinstitute.DPRK News Service @DPRK_News
346K Followers 100 Following Official News feed of Democratic Peoples Republic of KoreaPaycom @Paycom
35K Followers 850 Following Our HR and payroll software simplifies life for employees and transforms how people do business. Follow us for HR trends, tips and a closer look at our tools.Michael Nagle @MikeNagle84
124 Followers 291 Following Cook. Adventurer. Geneticist @EisaiUS. Not necessarily in that order. Opinions are my own.Huwenbo Shi (時胡�.. @shihuwenbo
839 Followers 607 Following Principal Scientist at Genentech; Postdoc at HSPH; PhD in Bioinf at UCLA; BS in Comp Sci at UCLA; Dog lover; Cat owner; Views are my ownAmelie Baud @AmelieBaud
927 Followers 542 Following Group leader at the Centre for Genomic Regulation in Barcelona. Social/indirect genetic effects, microbiome, statistical genetics.Ira Hall @irahall9
504 Followers 508 Following scientist; yale professor; genomics & data science; i speak for myself; he/himOur Future Health @ukfuturehealth
4K Followers 429 Following The UK’s largest ever health research programme, bringing people together to develop new ways to prevent, detect and treat diseases. Registered charity.Genevieve Wojcik, PhD.. @genandgenes
3K Followers 1K Following Asst Prof of Epidemiology in @JohnsHopkinsEpi, but views my own. || Genetic epi for diverse and admixed pops. || Mostly coffee, but still tired.Dr. Sanjay Gupta @drsanjaygupta
2.4M Followers 361 Following Associate Professor of Neurosurgery, Emory University Hospital; CNN Chief Medical Correspondent"how geneticists construe human genetic populations... [is] also sociopolitical. Genetic distinctions between human populations are not natural; they are the consequences of categorizations developed by geneticists" 🔥
Check out our paper in Science. We argue that more than content knowledge is required in science education. The sociopolitical in human genetics education | Science science.org/doi/10.1126/sc…
This is my work news!! Delighted to be this years Precision Diabetes Medicine Prize winner 🥇 Thank you to @novonordiskfond & @EASDnews @ImperialMDR
People of South Asian descent have a higher risk of developing type 2 diabetes, but a lack of research means we don’t understand why. Shivani Misra, this year’s winner of the Precision Diabetes Medicine Award, given jointly by the European Foundation for the Study of Diabetes and…
@timfrayling @drsusiemartin @athattersley @CO90s And at that time @nic_timpson was on a free transfer to team @markmccarthyoxf at the vastly more prestigious Oxford University; we got him back fortunately
@tconnellyRTE @rtenews Interesting how 'technological procedures' were often derided as being years away. Seems not.
BA.1 boosters should have been rolled out as soon as they became available medrxiv.org/content/10.110…
@Cobylefko Compare to Valencia Blvd in Valencia, California, about an hour outside Los Angeles.
I’ve reviewed @fergalkeane47’s book The Madness for the @spectator. It’s a haunting, powerful tale of war, trauma and “the potential of the monster within us all”. spectator.co.uk/article/the-tr…
The @OpenTargets family is growing again. Every new partner brings new perspectives into our missing to systematically identify drug targets. Looking forward to working with @markmccarthyoxf and many others at @genentech
.@genentech has joined the Open Targets consortium! Their expertise in biotechnology will complement the strengths of our current partners: @emblebi @sangerinstitute @GSK @bmsnews @sanofi @pfizer
6/And can we understand why ever more of us #Jews, together with other allies, now see that segregating merely stokes more grief and terror -- and that lasting peace will require -justice-, starting with honoring #rightofreturn not just for us, but for Palestinian cousins too?
@kasper_lage The photo is from when I was on the sea between Denmark and Sweden last summer - a happy happy place for me 🇸🇪 🇩🇰☺️🌼
DIAMANTE Consortium: 40+ new candidate causal genes for type 2 diabetes, “a step toward more effective clinical translation to improve global health for all irrespective of genetic background” @andrewpmorris73 @markmccarthyoxf @anubha_M_Oxf @NatureGenet: go.nature.com/3ldhVU7
@C_Glastonbury @markmccarthyoxf He would probably win the Eurovision too .. 😂
@DecMcCole @markmccarthyoxf @ibdseb @UKGastroDr @TheLFCLA Never ever in doubt!! 😝
A mural in Lviv, quoting Zelensky at his inauguration speech: “I don’t want you to have my portrait in your offices, because the president is not an icon or idol. Have there a picture of your children, and look into their eyes before making every decision” 📸 @kalvadosseeker
@doc_ibd @DecMcCole @markmccarthyoxf @UKGastroDr @TheLFCLA Can’t wait #YNWA
@doc_ibd @ibdseb @markmccarthyoxf @UKGastroDr @TheLFCLA Already as nervous as a bag of cats!
Yet, multi-ancestry studies don't replace group-focussed work. Our paper on genetic and translational effects on T2D+lipids traits in the Hispanic/Latino DIAMANTE subgroup is forthcoming, as well. Stay tuned! @NatureGenet @VUmedicine @VUMCgenetics @anubha_M_Oxf @markmccarthyoxf
So great to publish our latest T2D GWAS. Lots of juicy genetic & biological stories, benefiting from the most diverse set of genotyped samples. The work of a cast of 1000s but kudos++ to @anubha_M_Oxf & Andrew Morris who steered this supertanker to port rdcu.be/cNqDI
@markmccarthyoxf @splon @StephenORahilly And Steve’s point this would not fly in a clinical journal speaks to problems in making (editorial) judgements where domain-specific expertise is essential 2/2