CSF - Lymphatics @CSF_Lymphatics
keeping you updated on CSF - Lymphatics advances Science Capital, SZ Joined January 2022-
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Computational Fluid Dynamic Model Prediction of Enhanced Glymphatic Clearance in Response to Focused Ultrasound‐Mediated Blood‐Brain Barrier Opening advanced.onlinelibrary.wiley.com/doi/10.1002/ad…
How your brain's metabolic waste products get cleared during sleep, featuring the pivotal 2012 discovery of glymphatics @sciam @LydiaDenworth scientificamerican.com/article/how-sl…
Unique opportunity for a 5 years post-doctoral position in the brain barriers field for career transition towards an independent junior group leader. Check it out!
Mast cells regulate the brain-dura interface and CSF dynamics: Cell cell.com/cell/fulltext/…
Glymphatics and meningeal lymphatics unlock the brain-immune code: Immunity cell.com/cell-reports-s…
How are big proteins washed out from CSF, if they can’t go through the glymphatic system? Here is how: our new finding on glymphatic bypass || nature.com/articles/s4159… Congrats @Drieu_Antoine and Ben Plog and thank you to our many collaborators!
I would like to share our team's invaluable study on the non-invasive mechanical control of CSF outflow via the meningeal and superficial cervical lymphatics!
I would like to share our team's invaluable study on the non-invasive mechanical control of CSF outflow via the meningeal and superficial cervical lymphatics!
#STTT review: Zhang, Q., Niu, Y., Li, Y. et al. Meningeal lymphatic drainage: novel insights into central nervous system disease. Sig Transduct Target Ther 10, 142 (2025). doi.org/10.1038/s41392…
Excited to share the review by @mitchkim_mw on how brain washing is linked to Neuroimmunology || Glymphatics and meningeal lymphatics unlock the brain-immune code: Immunity cell.com/immunity/fullt…
🧩 "Lymphatic mysteries unzipped" Our N&V @NatureCVR on the beautiful study of @hansschoofs @makinenlab uncovering the mechanics behind the oak-leaf shape of lymphatic ECs!Fun to work together with Gwen Randolph! nature.com/articles/s4416… Original paper: nature.com/articles/d4158…
ECM remodeling occurs in the meninges during aging and following CNS trauma. In our latest work, led by @KateHitpass and @t_stevenson95, we show how this ECM remodeling contributes to the meningeal lymphatic drainage deficits seen in these conditions. tinyurl.com/572ypyas
The night shift: norepinephrine drives glymphatics A research highlight of an article recently published in Cell. #sleep #neuroscience @washumedicine @UofR @jonykipnis @MaiNedergaard @CellPressNews nature.com/articles/s4142…
Meningeal lymphatics-microglia axis regulates synaptic physiology: @CellPressNews cell.com/cell/fulltext/…
Here we discuss the recent beautiful paper in @CellPressNews from @NedergaardLab || sciencedirect.com/science/articl…
A tour de force review of the connections between the nervous and immune systems @Nature nature.com/articles/s4158… @QuintanaLabHMS
#WeekendRead! #LipidPower! Hugues &co show @NatureComms that lymphatic endothelial cells modify cholesterol into oxysterols, blocking PPARg in intratumor macrophages & monocytes, making them more inflammatory thus potentiating anti-tumor T cell responses!! nature.com/articles/s4146…
New in @ScienceImmunology! 🧠✨ We explored how the brain maintains equilibrium with the immune system. Our focus? The key player in immune tolerance and tissue function regulation: regulatory T cells (Tregs). Let’s dive in! science.org/doi/10.1126/sc…
An article in @jclinicalinvest — Gregory Wu, MD, PhD (@MS_ResearchDoc), & peers — describes huge strides in understanding CSF immune cells using single-cell RNA sequencing, factors driving MS, Alzheimer, Parkinson diseases. @maxim_artyomov @BrianEdelson2 bit.ly/4h7xLuk
Are you using 5xFAD mice to study Alzheimer’s disease? Our work @NeuroCellPress may be relevant to you 🐁 Age and sex are known to influence Aβ plaque burden in these mice. Here, we found that the transgene parentage is another strong determinant. (1/11) cell.com/neuron/fulltex…
Publications in the past week built substantially on our knowledge of the brain's waste disposal system—glymphatics—and the implications on sleep and brain aging. Featuring exceptional work by @NedergaardLab @MaiNedergaard and @jonykipnis Open-access; link below
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