Roaa Aljuaid | رؤى الجعيد @RoaaAj
Pathology resident PGY-3 at Medstar Georgetown University Hospital. Washington, DC, USA Joined March 2011-
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Two signet rings, which one is malignant? #CytoPath #PathTwitter #Pathology 🙏pmc.ncbi.nlm.nih.gov/articles/PMC90…
#1 of 2: 50F, non-smoker 🚭, lung mass 🫁 Diagnosis? 🧐🧐 A) pulmonary hamartoma B) pulmonary adenocarcinoma C) bronchial cell hyperplasia #CytoPath #PathTwitter #Pathology #PulmPath
Core needle biopsy of a retro areolar mass in a male. Let me know what stains you want! #pathology #breastpath #pathX #pathtwitter #pathresidents
Here is the tumour. Answers below.
Happy Tissue Tuesday! Let's focus on the ❤️. What’s your diagnosis for this left atrial lesion? (answer in comments) HPI: Adult patient w/ hx of syncopal episodes, now p/w acute hemiparesis. An echocardiogram reveals the culprit.
Phenomenal work by Dr. Laura Warmke regarding this rare sarcoma subtype. Happy to have been able to collaborate on the largest study yet of YAP1::KMT2A rearranged sarcomas: #pathtwitter #surgpath #BSTpath pubmed.ncbi.nlm.nih.gov/39641785/
Quiz for #pathology beginners. Which immunostains will label these cells/tissues/tumors? Answers: kikoxp.com/posts/15871 (with table of common stains). #medstudents #pathTwitter #path2path #dermpath #dermatology #dermtwitter #usmle #MedStudentTwitter #MedED #medtwitter
Master these cells in my module!↙️↙️↙️ classmarker.com/online-test/st… ✅ASC-H ASC-H is the appropriate category when there are rare cells with nuclear features suspicious for HSIL but not definitive Even a single high-grade cell warrants classification as ASC-H, ensuring further…
Cell from a pap smear, what is your interpretation?🧐 A) ASC-US B) ASC-H C) LSIL D) HSIL #CytoPath #PathTwitter #Pathology #GynPath
Bone marrow biopsy from a patient with untreated HIV revealing involvement by Kaposi sarcoma. Spindled tumor cells are seen forming irregular, dilated vascular spaces. What stain is positive in tumor cells? Answer: buff.ly/3fCYYdO #PathTwitter #PathArt
50F with nasal obstruction & recurrent nose bleeds, diagnosis? A) biphenotypic sinonasal sarcoma B) sinonasal angiofibroma C) sinonasal glomangiopericytoma D) sinonasal solitary fibrous tumor #ENTPath #PathTwitter #pathology #PediPath 🔬tumourclassification.iarc.who.int/Viewer/Index2?…
Nasal polyp with the following histology... 1. What are you Ddx? 2. What are your 5 favored IHC stains? #pathology #ENTpath #IHCpath
Keratin expression does not necessarily indicate carcinoma. Some sarcomas, such as this desmoplastic small round cell tumor (DSRCT), show extensive keratin immunoreactivity. Important to consider sarcomas in the differential diagnosis for keratin-positive tumors. #BSTpath
Desmoplastic Small Round Cell Tumor: Malignant mesenchymal neoplasm of polyphenotypic differentiation. Affects children/young adults, strong male predilection. Abdominal cavity is most common site. Poor prognosis. Recurrent t(11;22) involving EWSR1-WT1 genes #BSTpath #pathology
Women, 40s, recurrent pleural "collections" on imaging. Aggressive neoplasm on surgical biopsy, primary to thorax. Thank you twitter and colleagues at Mayo and MSK for sharing similar cases and allowing me to recognize this. WT1+, CK-. Not synovial, not SFT, not mesothelioma.
WT1-positive tumors: mesothelioma, serous ovarian CA, Wilms tumor & desmoplastic small round cell tumor (clone-dependent). Now there is one more: CIC-DUX4 fusion sarcomas. Check out this great case by @thoracicpath: these can mimic mesothelioma when thoracic.
WT1-positive tumors: mesothelioma, serous ovarian CA, Wilms tumor & desmoplastic small round cell tumor (clone-dependent). Now there is one more: CIC-DUX4 fusion sarcomas. Check out this great case by @thoracicpath: these can mimic mesothelioma when thoracic.

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