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Karthik Periasamy @karthik_onc

DNB Radiation Oncology | FRCR Clinical Oncology | Consultant Clinical Oncologist - PMGH | Papua New Guinea Joined May 2012
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Karthik Periasamy retweeted
SuyogCancer Profile Picture

Dr Amol Akhade @SuyogCancer

2 years ago

I don't know who should know this more , oncologist ( or patients ) from HICs or LMICs or both. Latest ESGO -ESP-ESMO gudilelines published do not recommend HIPEC for any stage of ovarian cancer, upfront or at relapse. One should avoid HIPEC outside clinical trial.

Karthik Periasamy retweeted
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ML Yap @yapml

2 years ago

Our latest work on radiation therapy in the APAC in @TheLancetOncol for #WCD2024. Gap in radiation therapy supply has widened over the last decade. Urgent investment needed. Led by amazing Dr Abu Awaad, w co-authors across the APAC RCA. authors.elsevier.com/a/1iW3W5EIIgLq… @GlobalRTCo

Karthik Periasamy retweeted
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Lauren Henke, MD, MSCI @lauren_henke

2 years ago

SO fun to get to highlight amazing work in GI RadOnc for PDAC @ASCO #ASCO23 ⚡️From ablative RT w/adaptive @radoncbme @MikeChuongMD, drugs like SOD mimetics @TaniguchiMD et al or DNA PK inhibitors @KarynAGoodman, + new tx like celiac RT, there is a LOT to be excited about 🤯⚡️

Karthik Periasamy retweeted
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Dr.Monica Avila @MAvilaMD

2 years ago

The era of radical cervical cancer frontline hysterectomy ends as #SHAPE trial randomization of simple vs radical hyst 1A2-1B1 (<2cm) confirms non-inferiority of a 3yr pelvic recurrence rate and 2ndary endpts PFS/OS are met #ASCO2023 @MoffittNews @MoffittGYNONC

Karthik Periasamy retweeted
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Nicholas Zaorsky, MD MS @NicholasZaorsky

2 years ago

Evaluation and management of metastatic cancer Thread 🧵 Thank you to @ISRSy and @the_RSS for giving me the opportunity to present this work and to many colleagues who have supported our publications and @NIH @theNCI @ACS_Research grant applications.

Karthik Periasamy retweeted
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Nico Gagelmann @NicoGagelmann

2 years ago

😱Emergencies in hematology😱 Malignant spinal cord compression (MSCC) A short 🧵 #MedTwitter 1/11

Karthik Periasamy retweeted
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Amir Safavi @safaviaa

2 years ago

60F w/ EGFR+ (Ex21) synch oligomet NSCLC #lcsm: 1.5 cm 🫁 primary, 0.4 cm asymp 🧠 met, painful 🦴met. To start Osi. #radonc consulted. 🧐 What would @DrBezjakRO and I (@UofTDRO @RadMedPM) do? 🗣️ Hammer Wisely ☢️🔨🦀! Now in @ASTRO_org @IJROBP #gyzone: tinyurl.com/523t82vr

Karthik Periasamy retweeted
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Ane Appelt @cancerphysicist

2 years ago

ACT-4: Key early data on dose reduction in low-risk anal cancer presented at #ESTRO23 by @DeeGeeee: 41.4Gy vs 50.4Gy ➡️ No apparently difference in 6mo response rate, improved treatment compliance #radonc @PLATOtrial @LeedsCTRU @CRUKresearch

Karthik Periasamy retweeted
_ShankarSiva Profile Picture

Shankar Siva @_ShankarSiva

2 years ago

Late breaking - #ESTRO2023. CORE RCT in 1-3 oligometastatic disease, Investigating SABR. N=245 patients, prostate and breast accounted for 220. No diff in G3+ tox. PFS HR=0.79, with 5mo ⬆️ of mPFS. ➡️ SABR + SoC better than SoC alone 🥳🎉🎊 @TROGfightcancer @DavePryorRO

Karthik Periasamy retweeted
_ShankarSiva Profile Picture

Shankar Siva @_ShankarSiva

2 years ago

Late breaking #ESTRO2023 - HypoG-01. N=1,222 patients, ➡️ non-inferiority of hypofractionated #breastcancer radiotherapy in patients needing nodal irradiation. ➡️Primary endpoint lymphoedema 24% vs 23%; ➡️secondary shoulder movement 23% vs 26% ➡️ no drop in safety, LRF #radonc

Karthik Periasamy retweeted
_ShankarSiva Profile Picture

Shankar Siva @_ShankarSiva

2 years ago

@TROGfightcancer @DrSanjayPopat @n8pennell @fifimcdrmh @BrendonStilesMD @TomVargheseJr @biniamkidaneMD @AndrearicFili @svporceddu @peters_solange @PBlanchardMD 🧵4/ modified disease-free survival (mDFS) is defined as recurrence not addressable by repeat local therapy ☢️🗡️. Using this strategy, 1 in 3 patients were free disease free at 5-years without costly , QoL impairing, lifelong 💉drug therapy. This is patient-centric! #lcsm #tssmn

Karthik Periasamy retweeted
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Ashish M. Kamat, MD, MBBS @UroDocAsh

2 years ago

In well selected patients - solitary tumors < 7 cm, no or unilateral hydronephrosis, minimal CIS - results with TMT are comparable to Radical Cystectomy #patientchoice #bladdercancer #bladdercancerMonth23 thelancet.com/journals/lanon… @TheLancetOncol @BladderCancerUS

Karthik Periasamy retweeted
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#TumorBoardTuesday @TumorBoardTues

2 years ago

#TumorBoardTuesday ➡️There are 170K bladder🦀patients yearly in the🇺🇸 👉If only ~20% of patients with metastatic disease are platinum-ineligible, this is not a small number‼️ Join us 05.09.23 at 8pm ET / 5pm PT as @PGrivasMDPhD & @rafee_talukder 🗣️how to manage these patients

Karthik Periasamy retweeted
DrYukselUrun Profile Picture

Yüksel Ürün @DrYukselUrun

2 years ago

A Must-Read Review! Exciting advancements in adjuvant therapy for EGFR mutation-positive #LungCancer @JAMAOnc @APassaroMD @peters_solange @TonyMok9 @OncoAlert @IASLC @ASCO @myESMO @OncBrothers @HemOncFellows jamanetwork.com/journals/jamao…

Karthik Periasamy retweeted
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Arndt Vogel @ArndtVogel

2 years ago

🔥RECISTv1.1 progression in oncology: Shades of gray🔥 @Cancer_Cell doi.org/10.1016/j.ccel… 🧐are RECISTv1.1 criteria still appropriate? ❓Is it time to consider lesion-to- lesion heterogeneity and a lesion-level approach 👉Interesting food for thoughts... @myESMO @OncoAlert

Karthik Periasamy retweeted
NicoGagelmann Profile Picture

Nico Gagelmann @NicoGagelmann

2 years ago

😱Emergencies in hematology😱 Tumor lysis syndrome (TLS) A short 🧵 #MedTwitter 1/19

Karthik Periasamy retweeted
MRCCTU Profile Picture

MRC Clinical Trials Unit at UCL @MRCCTU

2 years ago

🚨New results from the #STAMPEDEtrial in @TheLancetOncol are available today! 🔗bit.ly/3p7AuOr Findings confirm abiraterone combined with standard treatment helps people with metastatic #ProstateCancer live longer & also helps prevent the cancer from coming back. A 🧵

Karthik Periasamy retweeted
DrEmmaHolliday Profile Picture

Emma B. Holliday MD @DrEmmaHolliday

2 years ago

There has been a lot of 🔥discussion lately of short course radiation (SCRT) for locally advanced rectal cancer (LARC). I❤️SCRT bc it is convenient for working patients or those who travel for 🏥care. However, the RAPIDO update gives me pause. Let’s look at the history of SCRT:

Karthik Periasamy retweeted
jryckman3 Profile Picture

Jeff Ryckman @jryckman3

3 years ago

Is there a role for Local Tx of the Primary Tumor for Patients with Metastatic Cancer? 🚫Many studies demonstrate no benefit. 📌We performed a MetaAnalysis to evaluate the average effect of Local Tx across various tumors. A thread🧵#AMSM #PRIMETX redjournal.org/article/S0360-… 1/25

Karthik Periasamy retweeted
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Dipesh Uprety MD FACP @DipeshUpretyMD

2 years ago

Pt with Stage III NSCLC s/p definitive chemo-RT and on Durvalumab (few cycles) comes to you for a second opinion. Molecular profiling shows sensitizing EGFR mutation. What will you recommend? #LCSM @OncoAlert

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