Gyanu Lamichhane @BacteriaLab

Interests: Bacteriology and antibiotic resistance. Apolitical. I see glass quarter full. sites.google.com/view/lamichhan… Baltimore, MD Joined January 2019

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Gyanu Lamichhane @BacteriaLab

2 years ago

Drs. Story-Roller and Pankaj Kumar from our group have led multiple studies providing both molecular mechanistic basis and evidence for efficacy of dual b-lactams vs Mycobacterium abscessus. Here are our publications: sites.google.com/view/lamichhan…

Natasha Spottiswoode @NSpottiswoodeMD

2 years ago

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Erik Solheim @ErikSolheim

3 years ago

Heaven is a myth, Nepal is real! Sunset on a warm day at the lake Phewa 🇳🇵❤️💙💚🧡

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Gyanu Lamichhane @BacteriaLab

4 years ago

A good example of a new frontier. Exciting.

Kremer Laurent @KremerLaurent1

4 years ago

A good example of a new frontier. Exciting.

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Gyanu Lamichhane @BacteriaLab

4 years ago

Very exciting concepts at the interface of chemistry and infection biology that focus on unexplored yet fundamental aspects of bacterial cell wall.

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Jorik van Rijn @JorikvRijn

4 years ago

Below a cool teaser of what the microscopy setup from our latest preprint can do. Here, a Salmonella bacterium (arrow) divides on the surface of human intestinal cells. It then invades, and the epithelial cell reacts by instantly killing itself.

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Gyanu Lamichhane @BacteriaLab

4 years ago

Thank you for sharing this. A+ grade evidence of sensing and phagocytosis by a neutrophil. And also of cell polarity and kinetics of cytoskeletal rearrangement to achieve motility. Anyways, how is the neutrophil anchored to the glass tube?

Yoni - יוני (and Rebecca too) @Primary_Immune

4 years ago

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Gyanu Lamichhane @BacteriaLab

4 years ago

Indeed please join the effort. Antibiotic development/discovery is one of the main challenges of our times as several bugs have become resistant to many Abx we have. A good blog to read more about the need for new Abx is …ibiotics-theperfectstorm.blogspot.com.

Freel Meyers Lab @FreelMeyersLab

4 years ago

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Gyanu Lamichhane @BacteriaLab

4 years ago

This series has been a go-to reference for many protocols we use. Thank you for putting these together.

Prof Tanya Parish @ProfTanya13

4 years ago

This series has been a go-to reference for many protocols we use. Thank you for putting these together.

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Gyanu Lamichhane @BacteriaLab

4 years ago

Indeed an interesting microbe. Amazing heterogeneity in geno- and phenotypes. A bit more finicky compared to other mycos. Learned much and continuing to learn from this myco..

Kremer Laurent @KremerLaurent1

4 years ago

Indeed an interesting microbe. Amazing heterogeneity in geno- and phenotypes. A bit more finicky compared to other mycos. Learned much and continuing to learn from this myco..

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Gyanu Lamichhane @BacteriaLab

4 years ago

An interesting protein with domains reminiscent of a classical PBP, but it also exhibits a strong b-lactamase activity. M. abscessus mutant lacking this protein grows as a single clump and is wiped out from the lungs of mice...Thx @GlcNAcMurNAc for sharing this.

PeptidoglycanPapers @GlcNAcMurNAc

4 years ago

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Gyanu Lamichhane @BacteriaLab

5 years ago

Our team has taken one step towards addressing the challenge of developing new #antibiotics. Early results show promise but much work lies ahead to develop one that is useful bedside. We're determined to fight against #AMR, #TB and #mycobacteria. Our paper nature.com/articles/s4200…

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Gyanu Lamichhane @BacteriaLab

5 years ago

Dear graduate students, let this sink in. If you want to read more about what Albert did, I recommend the novel 'the greatest story never told' by Frank Ryan. Just like Albert's, your contributions are much needed and will be valuable to humanity.

Microbiology Society @MicrobioSoc

5 years ago

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David K Smith @professor_dave

5 years ago

You may wonder what else kills 1.5 million a year. It's tuberculosis. TB is completely curable & preventable, but because it only kills people in the developing world, those of us with privilege ignore it. Of course we want a Covid vaccine - but let's fix TB too!

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Gyanu Lamichhane @BacteriaLab

5 years ago

New investigators bringing their ideas and energy is always a good thing, for any field. You are welcome. Glad you are focusing on Mtb also.

Schmidt Lab @SchmidtLabHMS

5 years ago

New investigators bringing their ideas and energy is always a good thing, for any field. You are welcome. Glad you are focusing on Mtb also.

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Gyanu Lamichhane @BacteriaLab

5 years ago

To teach our kids real life skills - on Sundays they are allowed to run their home cafe for the family. Mom and I mentor and are loyal (only) customers. The two make their own menus and get to keep the money they make. They collaborate and compete. Here is the menu.