Russell Lamontagne @BostonBiotechRL
Joined December 2014-
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Our agreement with Otsuka will provide significant resources in furtherance of our goal of filing an IND related to our CD40 antagonist program in 2025 businesswire.com/news/home/2024…
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tandfonline.com/doi/full/10.10… Newly discovered juxtacrine signaling between membrane TNFα on granulocytic MDSCs and TNFR2 on inflammatory fibroblasts in the pancreatic cancer microenvironment maintains an immunosuppressive, myeloid-rich, T cell excluded, tumor stroma.
Inhibition of CD40L with Frexalimab in Multiple Sclerosis | NEJM nejm.org/doi/pdf/10.105… CD40/CD40L interesting roads ahead
We believe our anti-CD40 antibody has novel properties that differentiate it from prior CD40 antagonists, and we anticipate it could have uses in multiple autoimmune indications beyond Sjögren’s syndrome. businesswire.com/news/home/2023…
We are excited to have approval to bring our lead antibody into clinical trials businesswire.com/news/home/2023… #tnfr2
BITT To Present Update on CD40 Program at AAI 2023 - businesswire.com/news/home/2023… #AAI2023 #Immunology #autoimmunity
The SBIR funding will be used to complete the IND-enabling steps and initiate clinical trials of our anti-TNFR2 antibody, BIR2101 businesswire.com/news/home/2021…
TNFR2 as Therapeutic Target in Immunotherapy | ITT @DovePress dovepress.com/tnfr2-role-in-… Another great paper from Dr. Chen and his team #tnfr2
Boston Immune Technologies and Therapeutics Raises $10M Series A Financing | Business Wire businesswire.com/news/home/2021…
A TNFR2-hnRNPK axis promotes primary liver cancer development via activation of YAP signaling in hepatic progenitor cells cancerres.aacrjournals.org/content/early/…
Selexis and Boston Immune Technologies and Therapeutics (BITT) Enter Service Agreement to Advance BITT’s Lead TNFR2 Oncology Candidate | Business Wire businesswire.com/news/home/2021…
nature.com/articles/s4146… More confirmation of BITT’s hexagonal network (beehives) and dimers of the TNF superfamily for signaling from BMS #tnfsr #TNFR2
BeiGene Seeks FDA Approval for BTK Inhibitor, Strikes Oncology Deal with BITT | BioSpace biospace.com/article/beigen… #jobs
Russell Lamontagne retweeted
We are excited to announce that Boston Immune Technologies and Therapeutics and BeiGene has entered into an exclusive option and license agreement to develop novel #TNFR2 antagonists. Learn more: bit.ly/2ZnEb2C
Boston Immune Technologies and Therapeutics and BeiGene Enter into an Exclusive Option and License Agreement to Develop Novel TNFR2 Antagonists | Business Wire businesswire.com/news/home/2021…
Can an Old Vaccine Stop the New Coronavirus? nyti.ms/2JCcTxx
Countries with BCG vaccination (China, Korea, Ireland, Poland) policies are flattening the curve faster than non-BCG countries (US, Spain, Italy etc..). bcgandautoimmunity.org #bcg4covid19 Can an Old Vaccine Stop the New Coronavirus? nyti.ms/2JCcTxx
More evidence on role of soluble TNFR2 as biomarker. Diagnostic biomarker for acute adult T-cell cancers discovered biospectrumasia.com/news/26/15644/… via @AsiaBioSpectrum
Russell Lamontagne retweeted
@Lyfebulb and Helsinn Announce the Winners of the Third Annual Lyfebulb-Helsinn Cancer Innovation Summit & Award bit.ly/2S3tVbM
Lyfebulb and Helsinn Announce the Winners of the Third Annual Lyfebulb-Helsinn Cancer Innovation Summit & Award - markets.businessinsider.com/news/1028862358
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