Brain @Brain1878
Brain: A Journal of Neurology. Publishing leading studies in neurological science since 1878. academic.oup.com/brain London Joined January 2014-
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Upadhya et al. show that antibodies against LGI1 from patients with limbic encephalitis cause seizures in a laboratory model, adding to evidence for a causal role of LGI1 antibodies in seizure generation. tinyurl.com/2zear6tp
Husain et al. describe a recessive neurodevelopmental disorder characterized by intellectual disability, motor developmental delay and peripheral neuropathy, and associated with loss-of-function of the NUDT2 protein through disruption of mRNA homeostasis. tinyurl.com/2ex4y8bv
Antisense oligonucleotides (ASO) targeting an exon in SCN1A are being investigated as treatments for Dravet syndrome. Yuan et al. show that ASOs restore firing properties, GABAergic signalling, and sodium currents in the brains of Dravet syndrome mice. tinyurl.com/364zpm92
Stikvoort et al. report that nerve excitability in ALS is characterized by four unique patterns, each originating from changes in different membrane properties. Changes related to altered gating kinetics of slow potassium channels predict progression rate. tinyurl.com/munc7jdf
Diabetic neuropathy is often accompanied by mechanical allodynia. O’Brien et al. report that alterations in skin-derived factors contribute to allodynia, suggesting that it may be possible to develop topical treatments for diabetic neuropathy. tinyurl.com/5n82btcy
Odeh et al. examine how mutations in the SLC1A4 transporter give rise to neurodevelopmental delay and microcephaly. Using three mouse models, they show that Slc1a4 mutations lead to reduced serine import into the brain, resulting in impaired brain growth. tinyurl.com/3fnzvun9
In a study involving 400 glioma patients, Ng et al. use multivariate lesion-symptom mapping to shed light on neurocognitive systems with limited compensatory potential, and to disentangle the effects of intra- vs supra-tumoural resections on cognition. tinyurl.com/2zbtsv4j
Using cross-sectional structural MRI, Baumeister et al. identify two distinct patterns of brain atrophy in a memory clinic-based sample of older adults. These atrophy patterns may be used to predict clinical and cognitive trajectories of patients. tinyurl.com/2775sj8b
Explore our new Alzheimer's Collection - we invite our readers to enjoy some of the most stimulating and provocative papers on the neuroscience and neurology of Alzheimer’s disease. academic.oup.com/brain/pages/al…
By wirelessly recording signals from deep-brain stimulators in patients with Parkinson's disease in an outpatient setting, Soh et al. show that the STN – known for its role in motor control – also exerts control over attentional processes. tinyurl.com/mvuwy785
FTD and ALS share overlapping genetics and pathologies. Clayton et al. summarise recent evidence suggesting that presynaptic dysfunction is an early and common event in both diseases, and could be a target for future disease-modifying therapies. tinyurl.com/mx8xpkh8
Why do female patients with AD have more pronounced tau pathology compared to males? Wang et al. provide evidence that amyloid modulates tau phosphorylation in a sex-specific manner, contributing to faster neurofibrillary tau accumulation in females. tinyurl.com/5n7jfpf8
Fernandes et al. report that mice lacking the leptin receptor show reduced brain volume and neurogenesis as well as memory impairments in association with obesity. Restoring leptin receptor expression reversed the impairments in adult animals. tinyurl.com/3sxvwcpa
In a retrospective study, Eriksson et al. show that epilepsy surgery was able to halt and even reverse a decline in neuropsychological functioning in certain children by providing seizure freedom and the opportunity to discontinue antiseizure medication. tinyurl.com/2s3wu9u6
Sarton et al. investigate the relationship between neuroinflammation, measured in vivo using TSPO PET, and neurological outcomes in patients with coma following cardiac arrest or traumatic brain injury. tinyurl.com/2s9j4xa7; tinyurl.com/ftswa9u8
Apathy is a common complication of Parkinson’s disease. Gilmour et al. show that apathy can be related to a reduced ability to use information encoded in the frontal lobes about the outcomes of an action. tinyurl.com/35hz4kej; tinyurl.com/y9r843v7
Cheng et al. show in a mouse model of ischaemic stroke that a failure of myelin regeneration contributes to neuronal loss, whereas a pro-myelination drug promotes neuronal survival and functional recovery. tinyurl.com/2kbvct7d; tinyurl.com/47yc97sd
Neurostimulation can reduce seizures in drug-resistant epilepsy, but rarely results in seizure freedom. Anderson et al. show that more frequent stimulation during periods of lower seizure risk correlates with better clinical outcomes. tinyurl.com/4zdetnnw
Sánchez-Juan et al. reveal an association between serum GFAP and post-mortem tau pathology in patients with dementia, independent of amyloid deposits. Pre-mortem serum GFAP is negatively correlated with post-mortem brain weight. tinyurl.com/2n66efrs
Hydrocephalus is the most common disease requiring neurosurgery in children. Singh et al. show an association between mutations in the chromatin remodelling gene SMARCC1 and congenital hydrocephalus with a variety of syndromic features. tinyurl.com/3rxbrb72
Neurology Journal @GreenJournal
92K Followers 1K Following Neurology is the most widely read and highly cited peer-reviewed neurology journal. It is the medical journal for the American Academy of Neurology.Michael Okun @MichaelOkun
34K Followers 860 Following National Medical Advisor @parkinsondotorg Author 14 books https://t.co/EJCwDpEIw8 blog Professor @UF @fixelinstitute Associate Editor @JAMANeuro @DBSThinkTankAndreas Charidimou MD.. @a_charidimou
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8K Followers 990 Following Professor of Neurology at UC London Author of Ray Kennedy biography, Liverpool:The Hurricane Port, Mentored by a Madman, Brazil that Never Was and BrainspottingFrontiers - Neuroscie.. @FrontNeurosci
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5K Followers 1K Following Brain Communications is the #OA sister journal to @Brain1878. We aim to publish robust translational neuroscience studies.UCSF MAC @UCSFmac
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8K Followers 4K Following Neuroscientist. Prof @EdinburghUni Group Leader @UKDRI founding editor @BrainComms President @BritishNeuro (you can call me madame president). she/her 🧠 🔬 📚Practical Neurology @PracticalNeuro
16K Followers 171 Following Practical Neurology® magazine covers neurologic advances in epilepsy, stroke, Alzheimer's, Parkinson's, headache, ALS & more, plus issues facing physicians.British Neuroscience .. @BritishNeuro
38K Followers 1K Following A vibrant, progressive community of 2,750+ members creating an exciting and sustainable future for neuroscience. Join us! Tweets,RTs etc are not endorsements.Medscape Neurology @MedscapeNeuro
45K Followers 370 Following Medscape Neurology provides you with breaking medical news; reference on drugs,diseases,and procedures; and free CME.Masud Husain @MasudHusain
5K Followers 1K Following Professor of Neurology & Cognitive Neuroscience @UniofOxford, Editor-in-Chief @Brain1878, Fellow @NewCollegeOxElsevierNeuroscience @ELSneuroscience
57K Followers 1K Following Official page for Elsevier Neuroscience. Follow us for the latest neuroscience news, as well as info & discounts on our related products.Xin You Tai @XinYouTai
113 Followers 54 Following Neurology registrar, Oxford University hospitals Wellcome Trust DPhil studentAutoImmune Neurology .. @Mayo_AING
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5K Followers 4K Following Professor of Neurology and Complex Disease Genetics, King's College London. Co-Director UK MND Research Institute https://t.co/CR2sIAKgHI #MND #ALS Specialist.Cambridge FTD @CambridgeFTD
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8K Followers 2K Following The Brain Prize is the world's largest brain research prize - awarded to researchers with ground-breaking impact on neuroscience. DKK 10 million.Penguin Random House .. @penguinrandom
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113K Followers 6K Following Premier online and print content, written by and for #mentalhealth care physicians and professionals. Questions? Email: [email protected].Nature Neuroscience @NatureNeuro
407K Followers 268 Following News, commentary and research coverage from the international monthly journal publishing the highest quality of work in all areas of neuroscience.martin rossor @martinrossor
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6K Followers 139 Following Physical Medicine and Rehabilitation (PMR) Department at Mayo Clinic. Education about medical conditions and care is an important part of rehabilitation.Henry Marsh @DrHenryMarsh
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34K Followers 210 Following A neuroscience blog about molecules, mind and everything in between, written by @mocostNeuroscience Info @neuinfo
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747K Followers 471 Following Welcome to The Lancet, one of the world’s leading medical journals, published weekly since 1823.BMJ @bmj_company
62K Followers 6K Following https://t.co/Xpvd56ITee BMJ shares knowledge and expertise to help health professionals improve patient outcomes worldwide.Ali Jennings @Aliheartscience
438 Followers 130 Following Science communicator and now... DM for the @RPGeeksDnD! Views my own. Except where I've stolen them from someone else.London Stroke Forum @London_stroke
959 Followers 2K Following The London Stroke Forum bring together existing groups working on stroke research across London to encourage networking and collaborationFENS @FENSorg
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11K Followers 332 Following Our mission is to translate neuroscience discovery research into treatments for patients with neurological diseases. No medical advice is given via twitter.This #ML based review in @Brain1878 highlights factors that can be utilized to train ML algorithms to predict cognitive outcomes following #glioma #resection and these will act as a baseline #predictors for future #ML based models in #glioma. #AImodels #glioma #braintumour
Herbet et al. examine how machine learning algorithms can be used to predict cognitive outcomes following glioma resection. They argue that three factors should be used as predictors: resection topography, structure-function phenotype, and neuroplasticity. tinyurl.com/2s4abfbh
There are so many publications showing the impact of #SARSCoV2 on the brain that it is getting hard to keep track of the literature. This one was published this week at @Brain1878 (for nonneuroscientists, Brain Journal was founded in 1878 and is one of the best journals we can…
Had a great day at #BrainConf24 presenting alongside @mattr19909! Many thanks to the organisers and speakers for a fantastic programme 🧠 @Brain1878
Thank you @Brain1878 @braincomms @Mels_Science for such an amazing meeting & having me. Really enjoyed all talks, high quality datablitzes & posters as well as discussing our science
Hanna Willis gives the last talk of #BrainConf2024, following on from Steffan Tiedt and Zahraa Al-Ahmady in our Stroke session. Thank you to all of our speakers for your fantastic talks, and our volunteers for chairing and inviting questions. It's been a great day!
It's been a fantastic day at #BrainConf24 @Brain1878 filled with interesting talks and discussions The take-aways: 1. Neuroscience is an incredibly broad and exciting field to be in 🧠 2. Interdisciplinary research is key 🗝 3. Some neurons really like Marilyn Monroe!! 🤣
Neuroinflammation taking centre stage now at #BrainConf24 @Brain1878 🔥 🦠 Prof Hunt explores the issue of autoimmunity 🖥 @es_arman discusses the promise and challenges with medical AI 🧬 Prof Iversen presents the story of how our ancestry shapes genetic risk for MS Links ⬇️
Thank you for the opportunity to share some of our recent biobank research 🔬@Brain1878 @braincomms #BrainConf2024 If you would like to know more about an ECL plasma ptau217 assay 🩸 in a memory clinic cohort 🧍♂️🧍♀️please drop by poster 63 🗒️ @adamhdyer @SPKennelly @TUH_Tallaght
Sharing our recent work and vision for the future about sleep-aware DBS at the @Brain1878 conference in London #BrainConf2024
Great round of data blitzes up next at the #BrainConf24 @Brain1878 🗣 From cells to brains to the people behind it all - always inspiring to see the sheer range of research on offer
Thanks so much to everyone who gave up valuable lunch time to come and talk with me at poster 29 💬 Still more time to come visit! There's already been such great questions and discussion at #BrainConf24 @Brain1878
Very cool work related to apathy and frontal cortex @Brain1878 conference 2024 @beccasue99. I specifically liked the point about imprecise priors in apathetic brains.
Excited to present a poster today at the @Brain1878 Conference 2024 held at the Royal Geographical Society. This is ongoing work on treating cognitive dysfunction observed in patients with chronic Traumatic Brain Injury from @ccig_cambridge and UDA mdpi.com/2657348
Absolutely brilliant talk by @cathmummery summarising the recent therapy breakthroughs in dementia #BrainConf2024
Great talks thus far at @Brain1878 conference ranging from sleep to advanced dementia therapies to epilepsy with impressive gene therapy data by @LignaniLab_UCL
What a way to start the #WorldSleepDay! 💫 🧠 Great lectures from the stellar @ProfEspie and @VVyazovskiy at the @Brain1878 conference. From the neurophysiology to novel interventions - highlighting the fundamental role of #sleep!
Very cool work related to apathy and frontal cortex @Brain1878 conference 2024 @beccasue99. I specifically liked the point about imprecise priors in apathetic brains.
@TSpiresJones @Brain1878 @braincomms Thank you Tara! It was a pleasure to be there - amazing talks on genetic therapies and wish I could have stayed for the afternoon - but box packing calls!
Today is #worldsleepday and DPAG's @VVyazovskiy gave a talk at #Brainconf2024 @Brain1878 @KavliOxford @OxSCNi To learn more about his sleep-related research check out dpag.ox.ac.uk/research/vyazo…
Fantastic talks this morning! Good to see sleep and circadian rhythm taking a prominent place.
We kick off with our keynote speaker, Professor Colin Espie with his keynote lecture 'The Fall Guy'. #BrainConf2024
Great first session @Brain1878 conference! 🐭 Prof Vyazovskiy tackles the mystical process that builds during wake causing desire for sleep 🧠 Prof Mormann explores the link between sleep and 'concept cells' 💤 Dr Barateau discusses the neurobiology of hypersomnolence Links ⬇️
Very cool data from Prof Florian Mormann showing single neuron responses to concepts like Harry Potter characters with human micro wire recordings @Brain1878 @braincomms