Burstein lab @BursteinLab
Having fun with microbial genomic and machine learning @TelAvivUni burstein-lab.github.io Israel Joined September 2022-
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Burstein lab retweeted
Exciting to see our protein binder design pipeline BindCraft published in its final form in @Nature ! This has been an amazing collaborative effort with Lennart, @csche11h, @sokrypton, @befcorreia and many other amazing lab members and collaborators. nature.com/articles/s4158…
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Burstein lab retweeted
Fantastic new paper by Reese Richardson et al. "The entities enabling scientific fraud at scale are large, resilient, and growing rapidly." An enormous amount of work showing the extent of coordinated scientific fraud and involvement of some editors. pnas.org/doi/10.1073/pn…
Burstein lab retweeted
1/16 New pre-print from the Sternberg Lab! We uncover how temperate phages can use RNA-guided transcription factors to remodel the flagellar composition of their bacterial host and enhance their fitness. Find the preprint and full story here: tinyurl.com/mshwjd77
Burstein lab retweeted
How do plasmids kickstart gene expression in new hosts? Our new review in Plasmid: “Strategies for zygotic gene expression during plasmid establishment” with Nathan Fraikin (@tacc_c lab). Part of the #ISPB2024 special issue (Hamamatsu, Japan)🧵1/6 doi.org/10.1016/j.plas…
Burstein lab retweeted
📢Preprint out! Excited to share my final work from the @SorekLab! We mined phage dark matter using structural features shared by anti-defense proteins (viral tools that help phages bypass bacterial immunity) to guide discovery. Found 3 new families targeting immune signaling!
Burstein lab retweeted
Our @MolecularCell Spotlight on the Hailong anti-phage system from the Kranzusch lab! This defense uses "ssDNA tripwires" to trigger toxic ion channels 🧬⚡☠️ Fun write with Johannes Kühn!!
Our @MolecularCell Spotlight on the Hailong anti-phage system from the Kranzusch lab! This defense uses "ssDNA tripwires" to trigger toxic ion channels 🧬⚡☠️ Fun write with Johannes Kühn!!
Burstein lab retweeted
New pre-print(s) from the Sternberg Lab in collaboration with @LeifuChangLab! We uncover an unprecedented molecular mechanism of CRISPR-Cas12f-like proteins, which drive RNA-guided transcription independently of canonical promoter motifs. Full story here: tinyurl.com/mr3fd493
Burstein lab retweeted
Our latest story is now online @Nature! We discovered a phage defense system that deploys kilobase-long DNA homopolymers to protect against viral infection. Congratulations to all authors, and to the @WiedenheftLab for a fun and fruitful collaboration! nature.com/articles/s4158…
Burstein lab retweeted
We performed a dedicated search of anti-CRISPR proteins targeting the model E. coli Type IE CRISPR-Cas system and revealed AcrIE9 as a potent inhibitor and the most widespread anti-CRISPR protein in enteric bacteria. biorxiv.org/content/10.110…
Burstein lab retweeted
Excited to share our latest on the Type II Thoeris system! In collaboration with the Sorek and Kranzusch labs, we identify His-ADPR as a signaling molecule. Huge thanks to all involved—amazing teamwork! nature.com/articles/s4158…
Burstein lab retweeted
Congratulations to Rotem Sorek (@SorekLab) on your election to the US National Academy of Sciences as an International Member!!
Burstein lab retweeted
Excited to share our last collab paper, now out in print @ScienceMagazine!🎉 We reveal how dITP synthesis activates a SIR2 NADase effector to block phage infection! 🛡️🧬 science.org/doi/10.1126/sc…
Burstein lab retweeted
Hello Seoul! Excited to be at #RECOMB2025! If you're curious about alternative protein tokenization methods for protein language models, swing by poster #100. Would love to chat—see you there!
Burstein lab retweeted
Check out our new paper describing rAcrVIA1: an RNA anti-CRISPR that mimics guide RNAs to inhibit Cas13. Very fun project with stellar UW undergrad Victoria Hayes and collaboration with Ning Jia's group! science.org/doi/10.1126/sc…
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