Schraga Schwartz @SchragaSchwartz
Associate Professor @ Weizmann Institute of Science. RNA modifications | RNA biology | RNA therapeutics | Regulation of gene expression. weizmann.ac.il/molgen/Schwart… Israel Joined May 2018-
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Schraga Schwartz retweeted
@TheBrainOfPinky @viennabiocenter Big congratulations also to our 2 winners of best PhD student talks (pictured in the photo above), Anna Uzonyi from the lab of @SchragaSchwartz @WeizmannScience and Alexander Rotsch from Patrick Cramer's @mpgpresident lab @mpi_nat!
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Schraga Schwartz retweeted
How do cells efficiently respond to stress? Transcriptional stress responses are well-known—and in our latest study, we discover that cells use biomolecular condensation to redirect translation from old to new mRNAs 1/n biorxiv.org/content/10.110…
Schraga Schwartz retweeted
It's extremely vital that findings be reproducible. Our lab tried to reproduce the mRNA ac4C data when it first came out but failed to do so. This is important work by the @SchragaSchwartz lab
It's extremely vital that findings be reproducible. Our lab tried to reproduce the mRNA ac4C data when it first came out but failed to do so. This is important work by the @SchragaSchwartz lab
Schraga Schwartz retweeted
Delighted to share this study led by @elaine_zhou at @MarmorsteinLab @PennMedicine. The first structure of a eukaryotic RNA acetyltransferase provides insights into substrate binding, catalysis, and mutations useful for exploring Nat10 as a drug target. biorxiv.org/content/10.110…
We are delighted to share txtools R package with the community, serving as a streamlined starting point for detecting RNA modifications. Huge Kudos to @GarciaCamposM , who made it the beautiful and well-documented package that it is.
We are delighted to share txtools R package with the community, serving as a streamlined starting point for detecting RNA modifications. Huge Kudos to @GarciaCamposM , who made it the beautiful and well-documented package that it is.
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@TheBrainOfPinky @viennabiocenter Big congratulations also to our 2 winners of best PhD student talks (pictured in the photo above), Anna Uzonyi from the lab of @SchragaSchwartz @WeizmannScience and Alexander Rotsch from Patrick Cramer's @mpgpresident lab @mpi_nat!
@SchragaSchwartz @HoeferLab Hi Schragi, thank you for this analysis and explaining your thought process. It helps to realize what might cause artefacts and to make people aware how important workflows and sample selection are (both on the technical and bioinformatics side)!
It's extremely vital that findings be reproducible. Our lab tried to reproduce the mRNA ac4C data when it first came out but failed to do so. This is important work by the @SchragaSchwartz lab
Does mRNA get acetylated? Reanalyzing a dataset claiming that it does (Arango et al, Mol. Cell, 2022), we cannot find evidence supporting acetylation. Instead we find compelling evidence for major technical issue leading to miscalling of sites. sciencedirect.com/science/articl…
@SchragaSchwartz So cool! And so well done - we need more of this rigor to confine the ‘atrifacts’. Kudos to your team @SchragaSchwartz!
Nebulous modifications! Great work from the Schwartz lab! See also here for cautions tales on mRNA modifications: doi.org/10.1016/j.tibt…
Does mRNA get acetylated? Reanalyzing a dataset claiming that it does (Arango et al, Mol. Cell, 2022), we cannot find evidence supporting acetylation. Instead we find compelling evidence for major technical issue leading to miscalling of sites. sciencedirect.com/science/articl…
A very thorough reassessment of mRNA acetylation, by @SchragaSchwartz and team, highlighting the need for **in-depth** analysis.
Does mRNA get acetylated? Reanalyzing a dataset claiming that it does (Arango et al, Mol. Cell, 2022), we cannot find evidence supporting acetylation. Instead we find compelling evidence for major technical issue leading to miscalling of sites. sciencedirect.com/science/articl…
A special thank you to our Keynote Speakers @SchragaSchwartz, @susan_gasser, and @bvansteensellab and all other speakers for bringing together diverse topics from genome architecture to RNA modifications creating a high level of synergy between different fields.
@SchragaSchwartz Following your science since 2014. Very well deserved 👏👏👏👏
@BlavatnikAwards @WeizmannScience @NYASciences @IsraelAcademy @ShalevBenamiLab @SchragaSchwartz Awesome, congratulations Moran and Schragi!!
@SchragaSchwartz Congrats, Schragi! 🍾
@SchragaSchwartz Congratulations Schragi!🍾 Well deserved!
@WeizmannScience @SchragaSchwartz @ShalevBenamiLab Congratulations!
@IgorUlitsky @SchragaSchwartz @MeisterLab @BiochemistryWr1 Congratulations
@IgorUlitsky @SchragaSchwartz @MeisterLab @BiochemistryWr1 Big congratulations 🎊
@IgorUlitsky @SchragaSchwartz @MeisterLab @BiochemistryWr1 Congratulations!
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