Dr. Allison M Porman Swain @DrPorman
RNA Biologist. m6A in HOTAIR and Candida. Singing science. WiSTEM & DEI supporter. she/her. @DrPormanSwain.bsky.social aporman.wixsite.com/research Denver, CO Joined February 2019-
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A decade or two ago we could only dream of having genomes for all species of a major branch of the tree of life. Thanks to the Y1000+ Project, the dream is now reality! Kudos to @HittingerLab @DOpulente @Lab_LaBella @MarizethGroene1 & the whole TEAM science.org/doi/abs/10.112…
Couldn’t think of a better way to revive my account than sharing this amazing accomplishment with @4everBiochemist ! 🎉 Come check it out! cell.com/cell-reports/f…
Just. Share. Your. Plasmids. Enough with the MTAs. It's the age of synthesis. The material doesn't matter and all you are really doing is saving your peers time and money. The thing, once constructed, is an infinitely renewable resource. Just share it. Don't be weird.
This case study shows how nanopore sequencing is offering unprecedented insights into m6A and its critical role in the human brain — from development to regulation of neuronal activity — and its potential impact on neurological health. Read here: bit.ly/3SZnvd4 #WYMM
In my nesting era! #momademia
Excited to see our work now published in NAR Cancer! Thanks to everyone who was involved in this project! academic.oup.com/narcancer/arti…
My upcoming timeline is stressing me out 😬 Baby due 3/22 Start Assistant Prof position 7/1 Need to complete experiments, write paper draft, plan for ordering lab supplies for new position, organize and strategize lab transition in the next 6 weeks. Any advice? #momademia
where are my yeast people
where are my yeast people https://t.co/p9CnWCIr93
3 years of faculty searching… and finally just accepted an offer! Stay tuned for more news, but super excited to see this light at the end of a very long and treacherous tunnel!!!
immunometabolism friends! i am going to teach a lecture on "immunometabolites". do you have favorite papers? (e.g. on itaconate, kynurenine, ROS in neutrophils, other?) pls RT!
10 women in STEM! Pick it up and keep it moving @PravruthaRaman @KylaOst @may_khanna @DrEricaBioPhD @HeidiArjes @amandamjamieson @heydebigale @jessiemacalpine @HaydenMalone3 @LydiaHeasley
10 women in STEM! Pick it up and keep it moving @PravruthaRaman @KylaOst @may_khanna @DrEricaBioPhD @HeidiArjes @amandamjamieson @heydebigale @jessiemacalpine @HaydenMalone3 @LydiaHeasley
Thank you @CUCancerCenter and the C2S2 (Cancer Center Student Symposium) for the opportunity to share my research, advice, and fun parody with high school students today! Impacting and inspiring future scientists is definitely one of my passions ❤️
Big new article from me in @PLOSBiology on the past, present and future of science publishing. 6n 🧵 on what I try to do here. (RTs appreciated). 1/n doi.org/10.1371/journa…
Thank you for sharing! This will be super helpful for our next @CU_BMG DEAR inclusion & education meeting where we plan to discuss how to choose a PI and find mentors.
Thank you for sharing! This will be super helpful for our next @CU_BMG DEAR inclusion & education meeting where we plan to discuss how to choose a PI and find mentors.
In one RNA004 sample on a Prom, we get 196.8M DRACH motifs from 18G bases in 17M RNA004 reads (molecules), of which 12.78M are predicted to be m6A by Dorado with P>93%. We have 21 more of these to process! Here are some m6A-DMRs (>10 reads) between a lncRNA KD and control
Interesting insights here… “Being female, staying at the same K99 and R00 institution, and activating the R00 at a lower-funded institution are disadvantages to future funding success” “of all 2703 K99 awardees that transitioned to R00 awards, no K99 awardees were from HBCUs…”
Interesting insights here… “Being female, staying at the same K99 and R00 institution, and activating the R00 at a lower-funded institution are disadvantages to future funding success” “of all 2703 K99 awardees that transitioned to R00 awards, no K99 awardees were from HBCUs…”
You're welcome! geneseesci.com/wp-content/upl…
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25K Followers 2K Following Director of Arctic National Security, CU Boulder. Ecologist & chaser of permafrost & fires. In love with boglands. Represented by @zcosiniJeffrey Cameron @jccameron777
290 Followers 342 FollowingPouya Goleij @pouya_gl
59 Followers 103 Following MSs Molecular Genetics, working on molecular and clinical aspects of cancers, looking for a PhD position30% women in the Division, and still only interviewing men for open positions. Not a good look. I'm so tired.
Response from a colleague: "We sent out feelers to women, it's just so hard to find them." Try harder.
Mmmmmph, how did I forget about white poplar?! Imagine a kinda almost but not completely phyotene desaturase KO to make a kinda sorta white tree. Then add new colors. BLUE POPLARS I MUST
@KaraLMarshall this is such an important perk of being a scientist but sadly our trainees don't get to enjoy these perks often until they are burned out by all of the challenges. we need to start inviting early career scientists to experience this amazing aspect of being a scientist.
Fully rejuvenated after a lovely dinner with @myron_evansPhD and our visitor @Dr_Kevin_Pruitt after his incredible seminar at SCRI 🤯 … I can’t even begin to describe the wisdom he shared with us, but I’m feeling so inspired today. Thank you for your advice and honesty!
A decade or two ago we could only dream of having genomes for all species of a major branch of the tree of life. Thanks to the Y1000+ Project, the dream is now reality! Kudos to @HittingerLab @DOpulente @Lab_LaBella @MarizethGroene1 & the whole TEAM science.org/doi/abs/10.112…
Letters of support for grants have become increasingly onerous and just add to everyone’s workload. Apparently PIs can’t be trusted to simply state that they have collaborators. Instead, they have to put words in their collaborator’s mouths and then make them sign their names.
Development of topobiologically complex mini-colons that are able to undergo tumorigenesis ex vivo by integrating microfabrication, optogenetic and tissue engineering approaches @Nature @LFranciscoLM @TheLutolfLab @TaniaHubscher nature.com/articles/s4158…
PhD opportunity in chemical biology and antibiotic discovery with @gLarrouyM_Lab @TateScience and me! imperial.ac.uk/a-z-research/c…
"I was questioning if I belonged in academia – and whether or not someone was going to figure out that I didn’t belong!" - Dr Jourdan Davis, RWA Alum How having a publication framework helped her commit to her academic career: buff.ly/3zgor3N 🧡 #NewPI #ECRchat
warning that I always provide when sharing: it's LONG. (my search ended just at the start of pandemic lockdowns so I had apparently had a lot of ✨feelings✨ to process 😅)
If you're thinking about going on the faculty job market, take a look at this advice doc I just shared with helpimascientist.com: I collected my thoughts about the whole dang thing, from finding positions to negotiating a contract, & I hope y'all find it helpful!
Tremendous thanks to Teresa Lee @snickclunk for posting this exceptionally thorough and interesting guide to the academic job market on helpimascientist.com. I was either very naive and/or things were much simpler 23 years ago! helpimascientist.com/wp-content/upl…
Research shows that PhD students initially aspire to be professors, but that the desire wanes over time. Some think this is because of disillusionment with academia, while others attribute it to the challenging (impossible!) job market. What do you think?
Excited to share I was awarded the @UWMedicine @uwlabmedpath award for Justice, Equity, Diversity and Inclusion for 2023-24. Thank you for nominating me, @biologistbill. I don’t do this work for the recognition, but it’s nice to know people see the efforts & impact ♥️
New from @hitenmadhani and @pauletteoctopus Understanding the dynamic design of the spliceosome: Trends in Biochemical Sciences cell.com/trends/biochem…
I want to close with a big shoutout to @JosephGeorgeso2, from the lab, who led this reanalysis. Chasing down positive results is fun. Chasing down negative ones requires endurance. Kudos Joe for the persistence!
Does mRNA get acetylated? Reanalyzing a dataset claiming that it does (Arango et al, Mol. Cell, 2022), we cannot find evidence supporting acetylation. Instead we find compelling evidence for major technical issue leading to miscalling of sites. sciencedirect.com/science/articl…
They think I have POTS. #DysautonomiaTwitter #DisabilityTwitter please RT for visibility and give me your success stories. I have an infant and I’m scared.
Local environment in biomolecular condensates modulates enzymatic activity across length scales: nature.com/articles/s4146…