Cancer Control @CancerControl_
Follow us for the latest research developments in the cancer control field (IF 2.6). Published in association with @MoffittResearch. journals.sagepub.com/home/ccx Los Angeles, CA Joined July 2017-
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#EarlyOnsetCRC (<50) is rising & distinct: more left-sided/advanced disease, higher MSI-H/CIMP, and unique genomic/microbiome profiles. Action: lower screening age + risk-based, noninvasive, multi-omics/microbiome-guided care. #ColorectalCancer #CRC #Screening #PrecisionOncology
Oncology visits with Black patients & non-Black physicians: higher physician #ImplicitBias → more nonverbal synchrony; higher patient trust → more patient-led synchrony. Takeaway: pair bias-mitigation with workflow/communication training to strengthen equitable care. #Oncology
Density and maturity of Tertiary Lymphoid Structures (TLS) may predict clinical outcome in invasive #LungCancer. In a 750 pt cohort, high intratumoral TLS density independently predicted better OS, while higher TLS maturation predicted worse outcomes. #ImmunoOncology
Analysis of #GBD2021 (204 countries) data reveals that #PancreaticCancer deaths tied to high #BMI have surged since 1990. Women still higher burden, but men rising faster, esp. ages 20–49 & low-SDI regions. #Obesity prevention + equity-focused policy needed. #GlobalHealth
Homelessness ↑ #HBV/#HCV risk. Community outreach in housing + drop-in sites linked ~2,000 Texans to care (≈2/3 needed services). Targeting engagement sites based on specific goals can help practitioners maximize outreach to high-need populations. #HealthEquity #PublicHealth
Pilot, co-designed brief decision aid for #ColorectalCancer #Screening, targeted to ages 75–85 with limited #HealthLiteracy. 20→8 pages; understandability 44→75%, actionability 29→100%, clarity 71→~88. Supports #SharedDecisionMaking; RCT next. #CancerScreening #CRC
A 4-week pilot in breast/colorectal cancer survivors testing continuous glucose monitoring (#CGM) + Fitbit + tailored texts was acceptable & shifted exercise readiness into action/maintenance. CGM biofeedback may help drive #PhysicalActivity; larger trials needed. #DigitalHealth
In a survey of 1,357 Oregonians, Asian/Pacific Islander & unemployed/disabled adults reported more negative cancer beliefs & less confidence finding trustworthy info. Study highlight need for targeted, multilingual outreach via trusted channels to boost #CancerScreening & equity.
A pre-surgery prediction model using ultrasound, routine pathology, and simple blood tests, accurately flags axillary lymph-node spread in early #BreastCancer pts. In 287 pts it showed high accuracy and real clinical utility, supporting fewer unnecessary invasive procedures.
A routine blood score (SII) predicts patients with advanced non-small cell #LungCancer who benefit from PD-1/PD-L1 therapy. Low SII = higher response & longer PFS/OS, outperforming NLR/PLR. Data support using SII to guide selection & monitoring. #NSCLC #Immunotherapy #Biomarkers
Triple-mutated #AML (NPM1+FLT3-ITD+DNMT3A) is a highly aggressive subset. In 165 pts it comprised 6.7%, showed monocytic features, and had ~4-mo median survival despite similar remission. Low GNG4 expression linked to worse survival → potential prognostic #biomarker. #Leukemia
A simple pre-treatment blood test score (pretreatment pan-immune-inflammation value) powerfully predicted #RectalCancer pts who would respond better to neoadjuvant treatment. Pts with a low score did much better, pointing to more personalised, organ-sparing care. #Oncology
After limb-sparing surgery for lower-extremity soft tissue #sarcoma, adjuvant conventional #radiotherapy (RT) delivered better function & #QualityOfLife than hypofractionated neoadjuvant RT, with similar oncologic control. Data support prioritizing post-op RT. #RadiationOncology
3-trial meta-analysis (n=1,254): Cabozantinib + atezolizumab didn’t improve ORR/DCR vs cabozantinib alone, but lowered treatment-related adverse events (diarrhea, nausea, vomiting, hypokalemia). Combo may be a useful regimen for pts who can't tolerate cabozantinib monotherapy.
Electronic health record study maps distinct comorbidity patterns in early-onset #LiverCancer. Findings support race/ethnicity-tailored screening and targeted interventions to reduce disparities. #HealthEquity #CancerResearch #MachineLearning
Cancer Control study in ~30k #Pennsylvania teens reveals that #HPV #Vaccination still lags after COVID. ~67% start by age 17. Younger cohorts start earlier, but gains have plateaued. Earlier recommendations starting at age 9 & targeted outreach may accelerate #CancerPrevention.
Qualitative study in #RareCancers #Genomics surfaces 7 drivers of participant engagement and turns them into actionable communication & operations steps, helping teams boost recruitment/retention, build trust, and accelerate discovery. #Oncology #AYAOncology #PatientEngagement
Review published in Cancer Control proposes using the 1978 Alma Ata principles to redesign global cancer care—integrating oncology into strong primary health systems to boost prevention, early detection & #HealthEquity, ensuring advances reach all, regardless of geography/income.
A new Cancer Control scoping review finds optimal cancer referrals from #PrimaryCare should include detailed symptoms, relevant tests/exams, & the GP’s rationale. Clearer referrals can speed diagnosis & cut delays. #Oncology #CancerDiagnosis #EarlyDetection #HealthcareQuality
#CancerCare in #Georgia imposes a heavy financial burden, with significant out-of-pocket costs for most patients. ~75% of patients face major financial strain even with universal health coverage, & many take loans, mainly for diagnostics. #FinancialToxicity #HealthEquity #LMIC
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A. Emre Eşkazan, MD ... @eskazanae
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Matt foote @matt_footy
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Chuanbin Mao_phage_gr... @MaoPhageGroup
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Dr. Kimryn Rathmell @NCIDirector
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OncLive.com @OncLive
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Sumanta K. Pal, MD, F... @montypal
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ASCO @ASCO
149K Followers 2K Following Account of the American Society of Clinical Oncology & its affiliate the Association for Clinical Oncology. Assoc tweets labeled #ASCOAdvocacy. RTs ≠ endorse.
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Matteo Lambertini, MD... @matteolambe
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IARC @IARCWHO
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Pennsylvania Society ... @Penn_SOH
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NEJM @NEJM
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SelfMade Health @SelfMadeHealth
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600 Followers 500 Following Our mission is to empower personalized care by providing rapid precision oncology diagnostics to all patients.
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88 Followers 239 Following News and updates from SHORE (Surgical Health Outcomes Research Enterprise). A Division of the Dept of Surgery, University of Rochester Medical Center.
Hyperthermia Cancer I... @HCIoncology
470 Followers 716 Following Targeted, non-invasive cancer therapy that is FDA approved to treat cancers in combination with radiation therapy and/or chemotherapy. 866-520-4326Trends for United States
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