K. Leigh Greathouse @CancerMicrobes
Cancer biologist/dietitian | cancer survivor | developing dietary and microbial tools to improve cancer treatment | #MentorFirst | Associate Prof | @Baylor sites.baylor.edu/greathouse-lab/ Waco, TX Joined August 2016-
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As a cancer biologist, it pains me to watch “normal” cell biology being extrapolated from tumor-derived lines. Yes—primary cells are tough to grow and difficult to source—but if reproducibility is truly our goal, we must embrace the extra work. Let’s raise the bar. 🔬✨
📜New in @ScienceMagazine: not one but two papers from team MATCHMAKERS! The labs of David Baker @UWproteindesign and Chris Garcia @StanfordEMED published work that could revolutionise immunotherapy. The Baker lab unveil a generative AI pipeline to design precise binders for…
Many proteins bind RNA, yet we still don’t know what RNAs most bind because methods map one RBP at a time. In @CellCellPress, with the Jovanovic lab, we describe SPIDR – a method for mapping the RNA binding sites of dozens of RBPs in a single experiment. sciencedirect.com/science/articl…
First copies of my book are here!! As a new faculty member, I realized that in addition to my research job, I also had a leadership job…and I wasn’t prepared for that. This book is the guide I wish I’d had then, with the goal of helping others now. jenheemstra.com/book
Excited to share a milestone published in @NatureMedicine from our decade-long effort to build The Human Phenotype Project, a unique longitudinal cohort with unmatched depth of clinical and multi-omic profiling, enabling truly predictive, personalized medicine. Led together with…
New review in @Nature Reviews Gastroenterology & Hepatology: Intestinal pH is an underappreciated regulator of human gut #microbiome, influencing microbial pathway expression and enzymatic activity with direct links to health. Great collaboration! Link: nature.com/articles/s4157…
Excited to share that my PhD work is out in @Nature today! We engineered armoured CAR T cells to express therapeutic payloads only at the tumour site, to improve their safety and efficacy for the treatment of solid cancers. 1/14 nature.com/articles/s4158…
The microbiome is knocking on the clinicians' door @gianluca1aniro, @Siew_C_Ng, @GiovanniCammar9, @h_sokol, @EranElinav @Elinav_Lab @WeersmaLab & colleagues update key microbiome findings ripe to bedside and challenges: loom.ly/gmJBDAE
Are you thinking about doing a microbiome test?… After reading this article you might think twice… The microbiome for clinicians: Cell cell.com/cell/fulltext/…
Just needed a good laugh after discovering my USDA RFA was closed...This is what showed up as the picture for my new collaborator's Notion page - currently, how grant funding feels...just have to keep rowing.
If your gut had a digital twin, could we forecast cancer therapy outcomes before treatment? 🧬🤖 Today we publish the roadmap.👇
AlphaFold models of host-pathogen interactions elucidate the prevalence and structural modes of molecular mimicry 1.This study utilizes AlphaFold models to predict the structures of host-pathogen protein-protein interactions (PPIs), shedding light on the prevalence and…
I’m participating as a Star this year to raise money for the Waco Family Abuse Center. Would love your help to raise money and spread the word. Please repost and share. Help our campaign app.betterunite.com/familyabusecen…
Hosted our 3rd annual Texome Research Retreat at Fort Parker State Park with @CancerMicrobes, @kmckindl, Sayes group, VanNieuwenzhe group and Jon Lawson. Expanding outside the @Baylor walls next year!

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