Darragh @Darragh_Nim
PhD student | Non-coding cancer mutation | Epigenomics | Computational Biology | Bracken lab | @GenomicsCRT | @tcddublin Joined February 2021-
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It’s full steam ahead at the CRT writing retreat in Athlone with thesis being structured, chapters being written and papers being drafted 😓. But also time for some walks to clear the head and some cohort bonding and peer support !😀
Just released! In a joint effort with the @adrianbracken and @Dr_RPhillips labs, we discovered that diffuse midline glioma cells rely on specific cPRC1 complexes containing CBX4 and PCGF4 (BMI1). See the preprint biorxiv.org/content/10.110… and tweetorial to follow
The CRT Careers day is off to a great start with excellent talks from @scienceirel Teresa Brophy and @HSELive Eppie Jones! Breakout sessions on careers in (1)startups and VCs, (2)in health research and clinical settings (3) academia are up next!
3 weeks left to apply for this PhD position on enhancer biology in AML, importantly with updated stipend €20,000 p.a 9 days left for applications for a postdoc focussed on the role of PAX8 in ovarian cancer. worldwidecancerresearch.org/what-we-do/our… Please share & RT @UCD_Conway @UCD_SBBS
3 weeks left to apply for this PhD position on enhancer biology in AML, importantly with updated stipend €20,000 p.a 9 days left for applications for a postdoc focussed on the role of PAX8 in ovarian cancer. worldwidecancerresearch.org/what-we-do/our… Please share & RT @UCD_Conway @UCD_SBBS https://t.co/19jEN2Dc20
1/11 Our Preprint out today looking at EZH2 mutations in human growth disorders. We find novel mutational mechanisms & directly opposing chromatin & transcriptional defects caused by mutations associated with overgrowth versus growth restriction syndromes biorxiv.org/content/10.110…
Our research group @UCD_Conway @UCD_SBBS is expanding! We have two open post-doc positions and one PhD position to work on transcription factors and epigenetics in cancer. See link below for more details. Please share and RT! conwaychromatinlab.com/job-opportunit… #jobfairy @NinaOrfali
Delighted to have our CRT students in sunny Galway for their annual progress reviews! Fantastic to hear the interesting and diverse research projects and see how these young researchers are going from strength to strength every year!!!
Big congratulations to our speaker and poster prize winners 🏆 @Darragh_Nim @EllenFinnegan6 and Mike Rainey! Thanks to everyone for participating and see you all next year! #AICC2023
Prof @adrianbracken is inviting all @tcddublin Early Career #researchers in #lifesciences to join the Roundtable Event next Thursday - May 25th, with @CellPressNew Molecular Cell Editor, Dr Sara Miller – Register here today eventbrite.com/e/ecr-roundtab… #ECR #TrinityResearch
💙💛 Almost €5m will be shared by two UCD spin-out companies following investment from the Disruptive Technologies Innovation Fund (DTIF). 🧵 The Government announced €17.8m for 5 projects within the DTIF and UCD's @plasma_bound and EpiCapture are in two of these projects.
A team of scientists led by those in @tcdgenmicro has discovered new mechanisms involved in establishing cellular identity, which may have translational impacts in #cancer biology. Read more about this impactful #TrinityResearch at: bit.ly/40ZYT6G
Delighted to share our CBX7-JARID2 story now in @MolecularCell. To our surprise, @jxwangcheng and I uncovered a new mode of PRC1 recruitment by JARID2! Amazing team effort as always, thanks @adrianbracken lab and collaborators @LabVermeulen @pasini_lab cell.com/molecular-cell…
Finally out! 🔥 Thrilled to tell you that whole genome doubling can promote #cancer by altering the #chromatin 3D structure @Nature ! Great group effort with partners in chromatin 🧬 @elisa_oricchio @RuxandraLambuta @luca_nanni93 @dbc_unil @unil @EPFL_en nature.com/articles/s4158…
Last-minute winner from Lorcan Nimmo! It was 2-12 apiece, just minutes ago, when the @OulartBallagh No 12 popped up with this superb point to send @RCSIGAA into tomorrow's @ElectricIreland Ryan Cup Final against @ATU_Connemara
Excited to be joining the @EdinUni_IGC faculty appointed between @EdinCRC and @mrc_hgu The perfect environment for integrating our discoveries in cancer epigenetics with therapeutic development in childhood cancers Recruiting post-docs and students so get in touch. Please RT!
Excited to be joining the @EdinUni_IGC faculty appointed between @EdinCRC and @mrc_hgu The perfect environment for integrating our discoveries in cancer epigenetics with therapeutic development in childhood cancers Recruiting post-docs and students so get in touch. Please RT!
After more than 2 years of work, I am happy to share our latest preprint on CellCharter, a computational framework to identify and study cellular niches in large-scale spatial transcriptomics and proteomics data 🧵 1/12 biorxiv.org/content/10.110…
#PrePrint Alert 🔥 Happy to share #CellCharter 🗺️ by @MarcoVarrone @dbc_unil ! Identifying, characterizing, and comparing spatial clusters across multiple samples. CellCharter can be used with many #spatialomics platforms and is ..FAST 🚀 Check it out 👇 biorxiv.org/content/10.110…
Really looking forward to our next @irelandchrom webinar on Friday Jan 27th at 4pm BST / 5pm CET. Joanna Wysocka @StanfordMed will speak on ‘Making faces: transcriptional enhancers in human development, evolution and disease’. Please register at: lnkd.in/eDwrvDDV
Really looking forward to our next @irelandchrom webinar on Friday Jan 27th at 4pm BST / 5pm CET. Joanna Wysocka @StanfordMed will speak on ‘Making faces: transcriptional enhancers in human development, evolution and disease’. Please register at: lnkd.in/eDwrvDDV
Pleased to announce a full review of all phD supports. This will include financial supports, access to maternity and paternity leave, and visa requirements. Review will conclude early next year. First step will be engagement with researchers themselves.
Pleased to announce a full review of all phD supports. This will include financial supports, access to maternity and paternity leave, and visa requirements. Review will conclude early next year. First step will be engagement with researchers themselves.
Reminder about the upcoming AICC @irelandchrom @activemotif seminar tomorrow at 4pm Irish time. Registration details below👇
Reminder about the upcoming AICC @irelandchrom @activemotif seminar tomorrow at 4pm Irish time. Registration details below👇
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25K Followers 4K Following Dissecting disease mechanism. Single-cell, Epigenomics, Regulatory Genomics, Disease Genetics, Brain, Cancer, Metabolism. @MIT Prof, @MIT_CSAIL, @BroadInstituteThrilled to see both Lac-Phe studies published back-to-back—and to have my first paper among them! 🌟 A heartfelt thanks to @DavidFinlayTCD and @lynchielydia for their guidance, and kudos to the entire team at the @longlabstanford!
Work from the Long Lab @longlabstanford and our lab working with @DavidFinlayTCD on links between metformin, and eating (especially solid food) on Lac-Phe levels and appetite suppression @NatMetabolism
Happy St Patrick's Day! 🍀 Here is one of our incredible Irish cancer researchers, Professor @adrianbracken, explaining his vital research that we're proudly co-funding with @irishcancersociety.
It’s full steam ahead at the CRT writing retreat in Athlone with thesis being structured, chapters being written and papers being drafted 😓. But also time for some walks to clear the head and some cohort bonding and peer support !😀
As haematologists, we use the white count very specifically to inform us of immune system recovery after stem cell transplantation or as a “tell” of leukaemia relapse. But in general hospital practice, this perspective is absolutely spot on. nejm.org/doi/full/10.10…
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Delighted to see my ‘first’ first author paper published in Bioinformatics! In this paper we developed ‘Sensommatic’ - a pipeline to mine and predict Sensory receptor genes from vertebrate genome assemblies 🧬🐘 @GrahamMHughes @GenomicsCRT academic.oup.com/bioinformatics…
The difference between Normal & Standard Normal distribution:
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Delighted to have passed my PhD viva today! Massive massive thanks to my supervisors @pilib_ and @DaraCannon the wider lab groups, and my examiners. Also delighted to announce I'll be rejoining the Mullins Lab as a postdoc in the new year 🤸♂️ @NiamhAMullins back to NY 🎉🎉
“Instead of trying to reach across a cultural and intellectual divide…it is more efficient to develop a cadre of people who are truly bilingual in both research and clinical practice.” Academic clinician–scientists risk becoming an endangered species. nature.com/articles/s4159…
Conway lab Christmas party 2023 in full swing @Emma_JDoyle @daviesmolly13 @aisling1751
Just released! In a joint effort with the @adrianbracken and @Dr_RPhillips labs, we discovered that diffuse midline glioma cells rely on specific cPRC1 complexes containing CBX4 and PCGF4 (BMI1). See the preprint biorxiv.org/content/10.110… and tweetorial to follow
#ICBG2023 is getting very close! We hope everyone is excited to dive into #computationalbiology and #genomics with us🧬 📢Just a reminder: Registration will open at 9am on Monday in the Human Biology Building at @uniofgalway with the conference commencing at 9:30am.
Great fun visiting St. Andrews national school in Curragha with @aisling1751 for #scienceweek2023 today. Lemon volcanoes, homemade lava lamps and vinegar & baking soda rockets hopefully inspired some new budding scientists! @UCD_Conway @RCSI_Irl
Excited to share our collaboration with ENCODE to map enhancer-gene regulatory interactions across the human genome! We developed a new model that beats ABC by incorporating additional information on promoter class and enhancer-enhancer interactions. Thread 👇
Excited to share our latest work on bioRxiv! biorxiv.org/content/10.110… A highly collaborative effort with @ksmualim @karbalayghareh, @mayayayas, @kanishkadey, @evelynjagoda,@WangXijhu, @LarsMSteinmetz, @anshulkundaje, @jengreitz and many others from @ENCODE_NIH! Thread👇
🙋🏻♂️
Like this tweet if you would sign a petition to have @GNev2 banned from commentating on Arsenal games
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PARENTS: Make SURE you check your children's candy carefully this Halloween. I just found HETEROSKEDASTICITY in this snickers bar😲😱
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Very welcome news from @SimonHarrisTD that PhD stipends are to increase by €3000 from January for our @scienceirel students! Hopefully this is just the first step in addressing the consultation process recommendations and will also have an impact on stipends for ALL PhD students
From January, I will increase PhD stipends
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