Decipher Analytics @DecipherAnalyt2
Decipher Analytics is developing a fully integrated, health research informatics platform called a data commons. decipheranalytics.com Edinburgh, Scotland Joined October 2018-
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Around 10,600 fewer breast cancer patients have started treatment in the last year in England news.cancerresearchuk.org/2021/06/15/bre… The majority of these ‘missing’ breast cancers are early stage disease, based on provisional data from Public Health England’s Rapid Cancer Registration data
Many studies have looked at the use of Metformin in a wide range of other disorders, including heart disease and cancer fiercebiotech.com/research/diabe… A recent study indicates that the drug might help prevent lung inflammation in patients with COVID-19
Polymerases were thought to only work in one direction, DNA into DNA or RNA. Researchers have shown that RNA segments can be written back into DNA. lnkd.in/d9WVnhd The study focused on polymerase theta, which seems most similar to viral reverse transcriptases.
The number of COVID cases has now reached ~ 170M, millions of people are experiencing persistent symptoms nature.com/articles/d4158… Patient surveys have revealed an extensive list of symptoms, such as fatigue, dry cough, shortness of breath, headaches & muscle aches
BlueRock Therapeutics Parkinson’s disease stem cell therapy has started clinical studies. The first dose of DA01, pluripotent stem cell-derived dopaminergic neurons, was given out in a phase 1 test fiercebiotech.com/biotech/bayer-…
Researchers have used a bespoke adenine base editor to correct the sickle cell mutation in patient blood stem cells & in mice genengnews.com/news/base-edit… They were able to correct the mutation without double-stranded DNA breaks or inserting new segments of DNA into the genome
New insights into skull-based immune cells could inspire treatments for brain disease fiercebiotech.com/research/how-n… Some immune cells originate in the skull & migrate to the meninges without passing through the bloodstream. These immune cells appear to shield the brain from disease
The BBC's Rory Cellan-Jones (.@ruskin147) discusses his diagnosis with Parkinson's disease and the trial that he is taking part in that may help with the diagnosis and treatment of the disease. lnkd.in/gr-9p5P
Researchers have discovered a new & unique form of ALS genengnews.com/news/childhood… A study reveals 2 major findings: a single genetic cause of early-onset ALS & a novel, metabolism-associated, molecular pathway that may contribute to neurodegeneration in other forms of the disease
Bristol Myers Squibb has expanded the indications for it's multiple sclerosis drug Zeposia, which has now been approved to treat ulcerative colitis fiercepharma.com/pharma/bristol…
Results from a series of experiments in mice & human neurons suggest that an ion channel protein TRPC5 represents important contributor to tactile and spontaneous hypersensitivity to pain after inflammation. genengnews.com/news/non-opioi…
Research funded by @CR_UK suggests that widely-used anti-inflammatory drugs make tumours in mice more responsive to treatments that harness the power of the body’s own immune system to tackle cancer news.cancerresearchuk.org/2021/05/26/com…
A man who is blind has had glimmers of vision restored thanks to a high-tech treatment using optogenetics, which involves genetically altering nerve cells so they respond to light newscientist.com/article/227840…
The Big Interview: Gillian Docherty, CEO of @DataLabScotland and Chair of the Scottish AI Alliance via @TheScotsman scotsman.com/business/the-b…
A phase 2b trial of @NGMBio’ aldafermin in nonalcoholic steatohepatitis has missed its primary endpoint. fiercebiotech.com/biotech/ngm-s-… After 24 weeks of daily injections, people on aldafermin performed no better than their peers on placebo against key measures
Researchers have developed self-organising heart organoids that could be effective injury and in vitro congenital disease models tinyurl.com/2byfptmk These cardioids have the potential to revolutionise research into cardiovascular disorders and malformations of the heart
Researchers have designed an experimental drug that reversed key symptoms of Alzheimer's disease in mice sciencedaily.com/releases/2021/… The drug works by reinvigorating a cellular cleaning mechanism that gets rid of unwanted proteins by digesting & recycling them #DementiaActionWeek
The development of dementia late in life is associated with abnormal blood levels of dozens of proteins up to 5 years earlier sciencedaily.com/releases/2021/… Most of these proteins were not known to be linked to dementia before, suggesting new targets for prevention therapies
New insight into aggressive breast cancer could drive treatment choices fiercebiotech.com/research/new-i… Breast tumors that are both estrogen-receptor (ER)- and HER2-positive are typically slow-growing, while ER-negative, HER2-positive cancers are more aggressive
A major trial to that aimed to detect #OvarianCancer has failed to save lives bbc.co.uk/news/health-57… Initial results were promising, with annual blood tests detecting cases of ovarian cancer earlier. However, the final results showed the screening had failed to save lives
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Another busy day @discoverypark_ so great to step away from my desk for half an hour to enjoy the sunshine in the courtyard 😎
Very proud Mum here! Murray is the one in the shorts! @GWC_News
You'll want the sound on for this one... 🐘 🐘 🐘 Here are our Primary 3 pupils playing 'The Elephant' from this year's show Carnival of the Animals by Camille Saint-Saens. At Watson's, our youngest pupils learn to play cello through the Suzuki method. #OurValues #AimHigh
The BBC's Rory Cellan-Jones (.@ruskin147) discusses his diagnosis with Parkinson's disease and the trial that he is taking part in that may help with the diagnosis and treatment of the disease. lnkd.in/gr-9p5P
The Big Interview: Gillian Docherty, CEO of @DataLabScotland and Chair of the Scottish AI Alliance via @TheScotsman scotsman.com/business/the-b…
By combining our AI and machine learning with @AstraZeneca’s scientific expertise, our collaboration has discovered novel targets and transformed the culture of target discovery. Learn more about the progress, process and people behind our work: youtube.com/playlist?list=…
Is Alexa spying on you? Does your city council know where you’ve been today? Can your smart kettle be a witness in court? 😲 Sounds like a fascinating course!
Week 3 of our #dataEthicsMOOC starts today with @mooseabyte and @jamesks examining IoT, smart cities, smart homes and how data is collected and used >> edx.org/course/Data-Et… @EdinburghUni @BayesCentre @DataLabScotland #IoT #smartcities #smarthomes #datethics #data
What's been the biggest lesson for Julie Moulsdale over the past year? Julie has been great at encouraging the team to step away from their desks, and can often be found enjoying a ramble in her favourite nature spots. #ConnectWithNature #MentalHealthAwarenessweek
Great to get the thoughts of @diane_harbison, co-founder and CEO of @DecipherAnalyt2. In our latest blog, she looks at the development of genome sequencing in treating human diseases, and the crucial role it has played during the Covid pandemic. perceptivecommunicators.co.uk/our-news-pr-ag….
Keep an eye on our page this week as the team share stories about how connecting with nature has helped their mental health during the pandemic. For us, there's never been a more important time to support this conversation. #ConnectWithNature #MentalHealthAwarenessWeek
Selecting the right target remains one of the most important decisions we make in drug discovery. This new blog post explores how our investments in #genomics, functional genomics and #AI are already making a difference: bit.ly/2QGRdHt
We're really delighted to have been selected as finalists for Analytics Company of the Year in the @BritDataAwards! We're in really good company there with @ENA_analysis amongst others - congratulations to all the other finalists! predatech.co.uk/british-data-a… #Data #Awards #Innovation
Our campaign is 1 year old today. For a year we've been lobbying @RishiSunak @BorisJohnson to support us, our biz, our families. #AYearOn and we're STILL struggling. BIG thanks to Adele Carroll @SatellitePics @marcusBBbentley + #ForgottenLtd for creating this film. @craigie_b
#AYearOn We continue to ask for parity. We build the companies of the future. We employ 7.6 million people. We need support. We are the #ForgottenLtd. @MelJStride @SirGrahamBrady @itcontracting
We’re proud to be part of the Your Liver @mediaplanet campaign in today’s Guardian. Learn more about the importance of looking after your liver from our CEO Pamela Healy, online (bit.ly/3dcoTnG) and (bit.ly/31wT4jW).
A fantastic 3 days kicking off the #AlderleyPark #Oncology Development Programme this week! Fascinating insights and great discussion ➡️ roll on project pitches next week 🙌 @CRUKresearch @innovateuk @TheChristieNHS @AstraZeneca @MedDiscCat @Roche @MCRCnews @JNJInnovation @GSK
Dave Tudor of Medicines Manufacturing Innovation Centre highlights importance of data and skills to make a huge difference to life sciences industry discoveries and ambition. Sector needs another 30k highly skilled jobs. @ScotLifeScience @MackayAlix @DecipherAnalyt2
The countdown is on until the @Cambridge_Fest 2021! Our CSO Anne Phelan will join Jim Weatherall (@AstraZeneca), @MihaelaVDS (@Cambridge_Uni) & @drjbajwa (@MSFTResearch) to discuss hype vs reality in AI applied drug discovery. Sign up: festival.cam.ac.uk/events/ai-hype…
@DecipherAnalyt2 @AlderleyPark @innovateuk @CR_UK Congratulations!