Dr Navarro @DocNavarrow
Neuroradiologist. MD, PhD, EDiNR. Academic Editor at European Journal of Cancer Care Advisory Editorial Committee, @RevistaRADIOLO2 No medical advice. HGUC, Castellón Joined August 2022-
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✅ Anaplastic pleomorphic xanthoastrocytoma (PXA) Rare astrocytic tumor, typically in children/young adults but also seen in adults. 🔹 Often superficial with meningeal contact 🔹 ~40–60% harbor BRAF V600E mutation 🔹 High-grade → higher recurrence risk doi.org/10.1038/s41598…
✅ Anaplastic pleomorphic xanthoastrocytoma (PXA) Rare astrocytic tumor, typically in children/young adults but also seen in adults. 🔹 Often superficial with meningeal contact 🔹 ~40–60% harbor BRAF V600E mutation 🔹 High-grade → higher recurrence risk doi.org/10.1038/s41598…
🏥 A middle-aged patient presents with progressive headaches and seizures. 🔬Histology later revealed a tumor with a predominance of large blood vessels. What diagnosis would you consider?
👨⚖️A 46-year-old man presents with headaches. Interestingly, this case harbored a BRAF V600E mutation. What diagnosis would you consider?
🚀Astronauts pay a price for leading humanity to the stars✨ 👁️ In space, your eyes change. Up to 70% of astronauts on missions >60 days develop SANS (Spaceflight-Associated Neuro-ocular Syndrome), and lasting damage can persist for decades after flight. doi.org/10.1113/EP0929…
The cervicothoracic sign can help distinguish anterior from posterior mediastinal masses on chest X-ray: ✅ Positive → anterior mediastinum: border fades at/below the clavicles. ❌ Negative → posterior mediastinum: margin extends above the clavicles. doi.org/10.4103/jalh.j…
✅West Nile virus encephalitis. 🦟Suspect it in summer encephalitis in endemic areas, esp. elderly with fever, confusion, and flaccid weakness. 🧩MRI may show early isolated diffusion restriction before T2/FLAIR changes. pmc.ncbi.nlm.nih.gov/articles/PMC79…
✅West Nile virus encephalitis. 🦟Suspect it in summer encephalitis in endemic areas, esp. elderly with fever, confusion, and flaccid weakness. 🧩MRI may show early isolated diffusion restriction before T2/FLAIR changes. pmc.ncbi.nlm.nih.gov/articles/PMC79…
🤔💭Imagine a 72-year-old from Texas in late summer presenting with fever, confusion, and new-onset flaccid weakness. CSF shows lymphocytic pleocytosis. What’s your leading diagnosis?
✅Epidermoid cysts in occipital bone and cerebellum despite intact dura. Possible mechanism: ectodermal cells migrating via emissary veins or infiltrating dura microscopically. Highlights how these lesions may arise independently across compartments. doi.org/10.1016/j.inat…
✅Epidermoid cysts in occipital bone and cerebellum despite intact dura. Possible mechanism: ectodermal cells migrating via emissary veins or infiltrating dura microscopically. Highlights how these lesions may arise independently across compartments. doi.org/10.1016/j.inat…
👴71M with dizziness & vomiting for 1 month. Hx of head trauma 40y ago. An occipital bone lesion had been stable for 5y under follow-up. Now a new lesion appears in the adjacent cerebellum. What would you consider in the differential?
Thank you @DocNavarrow for highlighting this case. In our part of the world it will be popping eye opener. Please look at the intensity of enhancement. doi.org/10.1017/cjn.20…
✅Despite initial suspicion of tuberculous meningitis, the patient was ultimately diagnosed with neurosarcoidosis. Biopsy of mediastinal lymph nodes revealed non-caseating granulomas, and he improved with infliximab plus azathioprine. doi.org/10.1017/cjn.20…
✅Despite initial suspicion of tuberculous meningitis, the patient was ultimately diagnosed with neurosarcoidosis. Biopsy of mediastinal lymph nodes revealed non-caseating granulomas, and he improved with infliximab plus azathioprine. doi.org/10.1017/cjn.20…
Characteristic imaging patterns in toxic and acquired metabolic disorders of the central nervous system (schematic) 🧠🤮💊🫗

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