Katie Maurer @Dr_KatieM
Physician-Scientist @DanaFarber Cancer Institute | @CadwellLab alum | Postdoc, Cathy Wu lab Boston, MA Joined June 2015-
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Dr. Robert Soiffer, our inspirational leader @DanaFarber, giving the honorific @CIBMTR Mortimer Bortin lecture at #Tandem24 . So well deserved.
Thrilled to share our exciting #CART #singlecell data linking patient baseline immune characteristics with response to #axicel at #ASH2023 @SatyenGohil @IzzyGrabsk85482 @HouotRoch @DanaFarber
Thrilled to share our exciting #CART #singlecell data linking patient baseline immune characteristics with response to #axicel at #ASH2023 @SatyenGohil @IzzyGrabsk85482 @HouotRoch @DanaFarber
#ASH23 - Abstract 223 Outstanding presentation by @Dr_KatieM 👏🏻👏🏻👏🏻 Response to axi-cel is associated with: ✅The presence of > 0.5% circulating B-cells at baseline ✅Higher ALC/AMC at baseline ✅Enrichment of clonally expanded CD8+ TEM cells in IP #CARTcell
1/4 Excited to share #DIISCO 🪩, a Bayesian method for inferring cell-cell interactions over time in longitudinal #singlecell data 😱 DIISCO takes in cell type proportions and receptor-ligand expression and outputs cell state dynamics and cell-cell interaction networks! 🕺💃
This was a huge team and collaborative effort that spanned many institutions in the US and worldwide! Thank you to Emma Yin, @Majzner_Lab @Dr_KatieM @SandorDanielne @BenceDaniel2 @Kyttaro_Therapy @Kersten_MJ @StJude @DanaFarber @Stanford and our other co-authors! 8/n
Our paper about #azithromycin and post-alloHSCT relapse is published today in @BloodJournal ! Happy to share the final version doi.org/10.1182/blood.… and the comment by @Dr_KatieM and Robert Soiffer doi.org/10.1182/blood.…. @HIPI_Inserm @Institut_IRSL @APHP @univ_paris_cite
What a “harmless” antibiotic can teach us about GVL ashpublications.org/blood/article-…
Excited to share our recent paper in @journal_CHEST showing that in #intubated patients with #COVID19, prolonged prone position ventilation (PPV) is associated with decreased #mortality and fewer pronation/supination events doi.org/10.1016/j.ches…
[1/6 🧵] Today @NatureMedicine! Cellular dynamics monitored over time at the #SingleCell level reveals new insights into why some patients with large B cell lymphomas respond better than others to #CARTcell therapy rdcu.be/cVqVs Read the main takeaways below 👇!
Today #AACR22, don’t miss @njharlen presenting on single-cell analysis of cellular dynamics underlying clinical response to #CARTcell therapy in #collab work with Cathy Wu and @MarcelaMaus labs (Talk #3575). Then, read more of the story @medrxiv: medrxiv.org/content/10.110…
With appropriate safeguards, the Dana-Farber Division of Stem Cell Transplantation and Cellular Therapies found cellular therapies can be safely administered throughout the ongoing #COVID19 pandemic: ms.spr.ly/6012pFPJg via @BloodAdvances #stemcells #CARTcelltherapy
Check in with Katie Maurer, MD, PhD, to learn about the @DanaFarber experience providing stem cell transplants during the first #COVID19 surge #TCTM21 👉 Poster #424: ms.spr.ly/6018pIj8E
The PARCHED study: ICU residents more likely to be oliguric than their patients. I couldn't agree more. ncbi.nlm.nih.gov/pubmed/21156738
Sadaf Farsinejad @Sadaffars
30 Followers 77 Following PhD Candidate 👩🎓Cancer Cell Biologist 🔬 Passionate about Bioinformatics 🧬 Exploring the tiny wonders of life 🧫
Brittany Lockhart @BrittanyLo72767
0 Followers 409 Following
Emma Fink @EmmaFink
147 Followers 333 Following Oncology physician-scientist, Harvard MD/PhD 2020 (Ebert lab alum), BWH IM, Dana Farber/MGH Oncology Fellow
Florian Baumgartner @__Baumgartner__
422 Followers 730 Following Product Enthusiast - Head of Product @Moleculent; Helped develop #10xGenomics #Visium & #Xenium Products; Tweets=mine
Mpnppin2021 @mpnppin2021
0 Followers 133 Following
Smoasle @Smoasle151609
6 Followers 1K Following
Javier Bolaños Meade.. @GvHD_Meade
647 Followers 338 Following Fan of Aquinas, Boethius and Lady Philosophy, Anselm (and Gaunilo), John Dunce Scotus, Petrarch, and transplant immunology. GvHD student. Opinions my own.
Krishna Komanduri, MD.. @drkomanduri
13K Followers 5K Following Physician in Chief @UCSFCancer; Chief Hem/Onc @UCSFHealth; @ASTCT Past-President. Father of four, husband, shutterbug and aspiring pizzaiolo.
Corey Cutler @DrCCutler
3K Followers 367 Following Director, Stem Cell Transplant Program @DanaFarber Cancer Institute. President @ASTCT. Tweets are my own and not medical advice.
Amar Kelkar, MD, MPH,.. @amarkelkar
4K Followers 5K Following BMT/Hematology👨🏾⚕️➡️@DanaFarber + @BrighamWomens + @harvardmed | #CareDelivery🔬| @HPJournalClub | @HarvardChanSPH MPH ‘23 | @Cornell ‘10 |❤️Heme & Policy🤓
Moritz M. Reichert @MoritzMReichert
73 Followers 181 Following Resident Physician at University Hospital Erlangen, Department of Hematology & Oncology.
David Cordas dos Sant.. @DavidCdSMD
180 Followers 241 Following Clinician-Scientist from Munich | Postdoc at Dana-Farber Cancer Institute
Susan Ehret @SusanDFCI
917 Followers 2K Following Vice President of Strategic Planning & Insights @danafarber, passionate about healthcare communications. Avid cyclist & outdoor enthusiast. Views are my own.
Alex Afeyan @AAfeyan
12 Followers 71 Following
Jennifer Vidler @jennifer_vidler
181 Followers 441 Following Myeloid and Transplant Clinical Trials Fellow at King’s College Hospital. NIHR/BSH Researcher of the Year (Trainee) 2022. Passionate about clinical trials.
Tom Conklin @Tom_Conklin_
200 Followers 883 Following Enabling Single Cell Precision Genomics with @MissionBio
Repeat Diagnostics �.. @RepeatDx
745 Followers 3K Following RepeatDx is an accredited clinical diagnostics laboratory using Flow FISH analysis for telomere length measurement🧬(2 and 6 - Panel). Helping #IPF🫁 & #DC🩸.
Dr. Minoo Battiwalla @DrBattiwalla
2K Followers 1K Following Sarah Cannon Cancer Blood Cancer Network; #NIHBMTLateEffects #Celltherapy #HSCT #BMT #Survivorship; Tweets/opinions are personal
Alex Rampotas @ARampotas
1K Followers 1K Following Haematologist🔬🩸 MRC CRTF @uclcancer Roddie/Pule lab #CARTcell #MPN #translational_research 🇬🇷🇬🇧 Research support by @BloodCancer_Res & @the_MRC
Mohammad Saleem @saleemMMH
5K Followers 5K Following Research Instructor, AHA-CDA recipient, @annetkiraboc1 lab @VUMCClinPharm Immune cells & salt-sensitivity of blood pressure @UH_pharmacy alumnus, My views only.
Takahiro Maeda @TMHemOnc
396 Followers 407 Following Physician scientist, hematology/oncology @[email protected]
Ritodhish Ghosh @RitodhishG
0 Followers 220 Following
Kane Foster @KaneFos
468 Followers 703 Following I'm interested in how the immune system. PhD @uclcancer. I also like sci-fi literature & electronic dance music. he/him
Shubhra Bhattacharya @shubhs_codes
448 Followers 877 Following Grad student Bioinformatics at IJC (https://t.co/2R78fQ4b01), MDS,AML,Cohesin @intercept_mds ; Non-academic Interests: Literature, Djent, Cats.
Shafqat_Inam @ShafqatInam
2K Followers 2K Following Haematologist Interest in BMT, cell therapies, lymphoma and myeloma
Geraldine Gillespie @GMAGillespie
360 Followers 416 Following Professor of Molecular Immunology at University of Oxford
Gemiroquai @Gemiroquai
109 Followers 287 Following
Amirhossein Zarezadeh @A_Zarezadeh
29 Followers 140 Following Computer Engineer, current Developmental Biology MSc student at Royan Institute Data Scientist at @Cognetivity Interested in #ML and Computational Biology
Direna Alonso-Curbelo @DirenaAC
4K Followers 3K Following Group Leader at @IRBBarcelona | Postdoc @sloan_kettering, PhD @CNIOStopCancer | Cancer origins & context | Imagine Observe Perturb | 🌍🔬🎼
Enayat Nikoopour @ENikoopour
2K Followers 3K Following Studying immunopathological basis of diseases for therapeutic intervention and immunotherapy
Meri @dama_morada
36 Followers 617 Following
Richard Koche @RichardKoche
1K Followers 2K Following Computational epigenetics @MSKCancerCenter. Interested in how plasticity is encoded within the epigenome and how it's exploited during oncogenesis.
Jack Ghannam @JackYGhannam
56 Followers 166 Following MD-PhD Student @harvardmitmdphd | Immunology @HarvardGSAS
Chufan Zhang 张楚�.. @ChufanZhang2
118 Followers 399 Following 🇨🇳Previously medical student in Shanghai. Now PhD student at U of Toronto, Lupien Lab#Medical oncologist& Clinician Scientist to be!
Giuliano Filippini Ve.. @giulianopy88
194 Followers 234 Following Passionate about AML, cellular therapies, & immune escape. Based in Augsburg, Germany 🇩🇪, Originally from Paraguay 🇵🇾. UCA - Asunción
Ramon Massoni Badosa @rmassonix
3K Followers 2K Following Postdoc @nygenome @WeillCornell in love with single-cell multiomics, immunology, hematology, data science. I care about open science and education
Russell Zhang Kunes @russell_kunes
525 Followers 2K Following Computational biologist at Memorial Sloan Kettering Cancer Center, PhD in Statistics
Maulik Jani @dr_maulikjani
563 Followers 659 Following Postdoctoral Scholar (California Institute of Technology); PhD (The University of Chicago) Interests: Single-cell biology, Chemical biology, Neuroscience.
Bartek @grzywacz_bartek
443 Followers 566 Following Hematopathologist at BIDMC, Boston . Tweets, retweets and other posts are not medical advice.
Nicolas Beltran @nicolasvelezb
150 Followers 340 Following On a random walk. I mostly tweet about RL, AI safety, ML. PhD student @blei_lab Columbia.
Brian Shim @BrianHShim
105 Followers 176 Following PhD student at @LiuGroup, @BroadInstitute via @BBS_Harvard | Previously: Hahn Lab at @DanaFarber, Cell/Mol Biology @Northeastern
Hiroshi Imanaga @HiroshiImanaga
271 Followers 1K Following もう34歳 Kyushu University/hematology-oncology/B-cell precurser acute lympholastic leukemia/glucocorticoid/gymnastics/sake
Anahita Nodehi @anahita_nodehi
194 Followers 581 Following Research Associate (Postdoc) @BristolUni. Statistician in Causal Inference- missing data- survival analysis- directional statistics- machine learning
Zepeng (Phoenix) Mu @ZepengMu
216 Followers 705 Following Postdoc w/ @soumya_boston @BrighamWomens @broadinstitute | PhD w/ @yang_i_li @UChicago | B.S. @UCAS1978. Fun fact: my twin brother is @charlie_z_mu
Abhimanyu Gowda @Gowda_24
438 Followers 2K Following PhD student (immunoncology) @UniofOxford | Dir. @NucleateUK | Biotech, VC, public markets | Prev: @Cambridge_uni, Founder @cubiotechsoc, Fellow @join_polaris
Anurag Mishra @Mishra31A
430 Followers 2K Following PhD student @UCC 🇨🇮 CeNS Fellow @LMU Muenchen 🇩🇪 Master Intern @UniOslo 🇳🇴 Endosomal recycling, HER2+BC, drug resistance, ferroptosis, lipid metabolism
Emma Fink @EmmaFink
147 Followers 333 Following Oncology physician-scientist, Harvard MD/PhD 2020 (Ebert lab alum), BWH IM, Dana Farber/MGH Oncology Fellow
Florian Baumgartner @__Baumgartner__
422 Followers 730 Following Product Enthusiast - Head of Product @Moleculent; Helped develop #10xGenomics #Visium & #Xenium Products; Tweets=mine
Krishna Komanduri, MD.. @drkomanduri
13K Followers 5K Following Physician in Chief @UCSFCancer; Chief Hem/Onc @UCSFHealth; @ASTCT Past-President. Father of four, husband, shutterbug and aspiring pizzaiolo.
Javier Bolaños Meade.. @GvHD_Meade
647 Followers 338 Following Fan of Aquinas, Boethius and Lady Philosophy, Anselm (and Gaunilo), John Dunce Scotus, Petrarch, and transplant immunology. GvHD student. Opinions my own.
Susan Ehret @SusanDFCI
917 Followers 2K Following Vice President of Strategic Planning & Insights @danafarber, passionate about healthcare communications. Avid cyclist & outdoor enthusiast. Views are my own.
Moritz M. Reichert @MoritzMReichert
73 Followers 181 Following Resident Physician at University Hospital Erlangen, Department of Hematology & Oncology.
Amar Kelkar, MD, MPH,.. @amarkelkar
4K Followers 5K Following BMT/Hematology👨🏾⚕️➡️@DanaFarber + @BrighamWomens + @harvardmed | #CareDelivery🔬| @HPJournalClub | @HarvardChanSPH MPH ‘23 | @Cornell ‘10 |❤️Heme & Policy🤓
Aaron Logan, MD, PhD,.. @hemedoc
7K Followers 424 Following Professor, UCSF hematology/BMT. Translational researcher interested in leukemia, MDS, HLH, MRD, post-HCT relapse, GVHD, & immune recon. Photos: pyknosis (IG)
David Cordas dos Sant.. @DavidCdSMD
180 Followers 241 Following Clinician-Scientist from Munich | Postdoc at Dana-Farber Cancer Institute
Dr. Minoo Battiwalla @DrBattiwalla
2K Followers 1K Following Sarah Cannon Cancer Blood Cancer Network; #NIHBMTLateEffects #Celltherapy #HSCT #BMT #Survivorship; Tweets/opinions are personal
Tom Conklin @Tom_Conklin_
200 Followers 883 Following Enabling Single Cell Precision Genomics with @MissionBio
Jennifer Vidler @jennifer_vidler
181 Followers 441 Following Myeloid and Transplant Clinical Trials Fellow at King’s College Hospital. NIHR/BSH Researcher of the Year (Trainee) 2022. Passionate about clinical trials.
David Russler-Germain.. @dgermain21
3K Followers 1K Following Oncology Instructor @SitemanCenter @WUSTLmed | lymphoma/leukemia researcher @LabFehniger | all views 100% my own
Alex Rampotas @ARampotas
1K Followers 1K Following Haematologist🔬🩸 MRC CRTF @uclcancer Roddie/Pule lab #CARTcell #MPN #translational_research 🇬🇷🇬🇧 Research support by @BloodCancer_Res & @the_MRC
Mohammad Alhomoud @moh7madhomod
1K Followers 570 Following BMT fellow @MSKCancerCenter | alum of @WeillCornell hem/onc fellowship | #bmtsm #Celltherapy
Bartek @grzywacz_bartek
443 Followers 566 Following Hematopathologist at BIDMC, Boston . Tweets, retweets and other posts are not medical advice.
Maulik Jani @dr_maulikjani
563 Followers 659 Following Postdoctoral Scholar (California Institute of Technology); PhD (The University of Chicago) Interests: Single-cell biology, Chemical biology, Neuroscience.
Richard Koche @RichardKoche
1K Followers 2K Following Computational epigenetics @MSKCancerCenter. Interested in how plasticity is encoded within the epigenome and how it's exploited during oncogenesis.
Enayat Nikoopour @ENikoopour
2K Followers 3K Following Studying immunopathological basis of diseases for therapeutic intervention and immunotherapy
Direna Alonso-Curbelo @DirenaAC
4K Followers 3K Following Group Leader at @IRBBarcelona | Postdoc @sloan_kettering, PhD @CNIOStopCancer | Cancer origins & context | Imagine Observe Perturb | 🌍🔬🎼
Amirhossein Zarezadeh @A_Zarezadeh
29 Followers 140 Following Computer Engineer, current Developmental Biology MSc student at Royan Institute Data Scientist at @Cognetivity Interested in #ML and Computational Biology
Gemiroquai @Gemiroquai
110 Followers 287 Following
Geraldine Gillespie @GMAGillespie
360 Followers 416 Following Professor of Molecular Immunology at University of Oxford
Shafqat_Inam @ShafqatInam
2K Followers 2K Following Haematologist Interest in BMT, cell therapies, lymphoma and myeloma
Shubhra Bhattacharya @shubhs_codes
448 Followers 877 Following Grad student Bioinformatics at IJC (https://t.co/2R78fQ4b01), MDS,AML,Cohesin @intercept_mds ; Non-academic Interests: Literature, Djent, Cats.
Kane Foster @KaneFos
468 Followers 703 Following I'm interested in how the immune system. PhD @uclcancer. I also like sci-fi literature & electronic dance music. he/him
Mohammad Saleem @saleemMMH
5K Followers 5K Following Research Instructor, AHA-CDA recipient, @annetkiraboc1 lab @VUMCClinPharm Immune cells & salt-sensitivity of blood pressure @UH_pharmacy alumnus, My views only.
Takahiro Maeda @TMHemOnc
396 Followers 407 Following Physician scientist, hematology/oncology @[email protected]
Russell Zhang Kunes @russell_kunes
525 Followers 2K Following Computational biologist at Memorial Sloan Kettering Cancer Center, PhD in Statistics
Giuliano Filippini Ve.. @giulianopy88
194 Followers 234 Following Passionate about AML, cellular therapies, & immune escape. Based in Augsburg, Germany 🇩🇪, Originally from Paraguay 🇵🇾. UCA - Asunción
Ramon Massoni Badosa @rmassonix
3K Followers 2K Following Postdoc @nygenome @WeillCornell in love with single-cell multiomics, immunology, hematology, data science. I care about open science and education
Jack Ghannam @JackYGhannam
56 Followers 166 Following MD-PhD Student @harvardmitmdphd | Immunology @HarvardGSAS
Mericien Venzon, PhD @MericienVenzon
594 Followers 554 Following Incoming Pediatrician-Scientist in training @UCLAMCH | Gut microbiome, Allergy & Immunology | DEI 🇵🇭@thecyfamorg | @NYU_MSTP @CadwellLab @UCLA alum | 🧗♀️🥊
Dr. Bishoy M. Faltas @FaltasLab
7K Followers 7K Following Physician-Scientist. Chief Research Officer @EngIPM. Gellert-John P. Leonard Scholar, Associate Professor @WeillCornell. Husband & father. RTs ≠ endorsements
Caroline Sokol MDPhD @sokol_mdphd
2K Followers 726 Following Assistant Professor at HMS and MGH; Director Stanbury-PSP at MGH Int Med Residency; Allergist/Immunologist; she/her/hers; @[email protected]
Dr. Erika Haydu @ErikaHaydu
416 Followers 414 Following #Lymphoma physician and clinical investigator @MGHCancerCenter, by way of @MGH @DanaFarber @BrighamWomens @ColumbiaPS @WilliamsCollege | views my own
Akoya Biosciences @AkoyaBio
8K Followers 7K Following Our mission is to bring context to biology & human health through the power of spatial phenotyping. We are The Spatial Biology Company®. 🧬🥼 #akoyabio
Charlie Dai @Charlie_S_Dai
369 Followers 563 Following Medical oncology fellow and physician-scientist @DanaFarber / @MassGenBrigham via IM @MGHMedicine, CCLCM '18, Rice ‘12. Opinions are my own.
Joshua Fein @joshuaafein
924 Followers 1K Following Weill-Cornell hem/onc fellow; interested in big data and small data in acute leukemia and allo transplant; dad to 3 very silly kids
Brian Shim @BrianHShim
105 Followers 176 Following PhD student at @LiuGroup, @BroadInstitute via @BBS_Harvard | Previously: Hahn Lab at @DanaFarber, Cell/Mol Biology @Northeastern
Iannis Aifantis @iannisaifantis1
9K Followers 864 Following Cancer Research & Immunology. Professor and Chair @NYUGSOM_Path @nyugrossman. My Instagram account is more fun. Expressed opinions represent only Me/Myself/I.
Rong Fan @RongFan8
9K Followers 1K Following Harold Hodgkinson Professor of Biomedical Engineering and Pathology, Yale University https://t.co/kLH8WPg2c2 https://t.co/kbDKoBh9Ak https://t.co/MduFkomdDj
Nicolas Beltran @nicolasvelezb
150 Followers 340 Following On a random walk. I mostly tweet about RL, AI safety, ML. PhD student @blei_lab Columbia.
Amit Sud @amit_sud
700 Followers 1K Following haemato-oncologist & @wellcometrust early career fellow. #genetics #cancer. @DanaFarber @broadinstitute @UniofOxford @ICR_London 🧬🔴🔬💻🚴🏽♂️🥁🌱🌍
Alex Afeyan @AAfeyan
12 Followers 71 Following
Ron S. Gejman MD, PhD @rongejman
2K Followers 4K Following Heme/Onc fellow @columbiacancer. Former IM @brighamwomens @harvardmed. MD/PhD @TriIMDPhD @MSKCancerCenter.
Jake Rosenberg @JRosenbergMDPhD
557 Followers 846 Following Infectious Diseases @MGH_ID and @BWH_ID. Tuberculosis Immunology @RagonInsitute and @HarvardChanSPH.
Alex Chamessian @achamess
3K Followers 5K Following Physician-scientist and Pain Medicine fellow @WashUPain | post-doc @robgereau lab | formerly @DukeMSTP | https://t.co/xEU4rrLb4z
Nurefsan Sariipek, MD @nursariipek
840 Followers 638 Following Postdoctoral Fellow @vangalenlab @brighamresearch @harvardmed @broadinstitute | MD’22 @ankarauni | Aspiring Internist | Interested in blood cancers
Joshua Brandstadter M.. @JBrandMDPhD
272 Followers 542 Following Physician-Scientist @PennCancer ˑ Stroma Sleuth ˑ Storming Castles @CureCastleman ˑ I love immunology ˑ Views are my own, and not medical adviceCongratulations Nicoletta Cieri, MD, PhD, @DanaFarber who was awarded @nmdp_org's Amy Strelzer Manasevit Research Program grant. Cieri will receive $400,000 to further her research re: allogeneic hematopoietic cell transplantation. #alloHCT Read more ▶️ ms.spr.ly/6013cj5aB
.@ArielleMedfordMD & @dradityabardia present the case of a woman with metastatic triple-negative breast cancer with secretory features who had disease progression on multiple lines of therapy, but responded rapidly and dramatically to larotrectinib. spklr.io/6013WvLL
Congratulations to @DrCCutler Who begins his service as ASTCT president! Thank you @DrMiguelPerales for your leadership over the past year. #Tandem24
@CIBMTR Mortimer M. Bortin Lecture recipient Rob Soiffer from @DanaFarber! Congrats and well deserved, Rob! True giant in the field and simply a great guy to know! @ASTCT @nmdp_org
Dr. Robert Soiffer, our inspirational leader @DanaFarber, giving the honorific @CIBMTR Mortimer Bortin lecture at #Tandem24 . So well deserved.
#tandem24 Wu: the path to tumor neoAg targeting
This morning at #Tandem24, Catherine Wu, MD @DanaFarber will present her research, Discovery and Target mHAgs, during the plenary session: Novel Antigen Discovery for Transplant and Cellular Therapies.
#tandem24 Wu: GVL associated minor HAgs (GRFS mHAgs) assoc with lower incidence of relapse.
Congratulations to ASTCT New Investigator Award winners @FahminB_MDPhD of @DukeCancer, and @amarkelkar of @DanaFarber. #Tandem24
Feel so lucky to be a part of this team! My intro to comp bio and learned how great science gets done
1/6 Excited to share our new preprint, out today on #biorxiv, a large #singlecell effort studying response to adoptive cellular therapy for relapsed myeloid malignancy after #HSCT !!
Couldn't be more proud! Phenomenal teamwork CathyWu @Dr_KatieM @cam_park @ShouvikMani & others!We derived effective anti-leukemic mechanisms from an archetypal adoptive cell therapy-spatiotemporal modeling w/#DIISCO+CODEX+ functional validation of cell types coordinating response
1/6 Excited to share our new preprint, out today on #biorxiv, a large #singlecell effort studying response to adoptive cellular therapy for relapsed myeloid malignancy after #HSCT !!
A personal favorite part of this paper- experimental data to strengthen our computational findings! Co-culturing CD8+ CTLs with autologous (!) AML cells leads to significant increases in IFN-g and CD137 expression, confirming CTL recognition of AML + subsequent activation!
Great work @Dr_KatieM - looking forward to seeing this come out as a full publication soon. 👍 #AML #HSCT #BMT #immunotherapy
1/6 Excited to share our new preprint, out today on #biorxiv, a large #singlecell effort studying response to adoptive cellular therapy for relapsed myeloid malignancy after #HSCT !!
Excited for my first #ASH23! Presenting some of our results this afternoon in Room 11 on a unique immunogenetic circuit that limits T-cell attack in hematologic malignancies, under the superb mentorship of @pbachi @ShuklaSachet @jmolldrem
Go go @Dr_KatieM !!
#ASH23 - Abstract 223 Outstanding presentation by @Dr_KatieM 👏🏻👏🏻👏🏻 Response to axi-cel is associated with: ✅The presence of > 0.5% circulating B-cells at baseline ✅Higher ALC/AMC at baseline ✅Enrichment of clonally expanded CD8+ TEM cells in IP #CARTcell
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