EMBO Viruses of Microbes 2018 @EMBOVoM2018
Science, networking and fun about microbial viruses! meetings.embo.org/event/18-virus… Wroclaw, Poland Joined January 2018-
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@EMBOVoM2018 Thank you very much #EMBOvirus18, it is really a great success. Though the conference has ended, but the special issue "Viruses of Microbes V" is still open @Hallison67 . If you are interested in this project, please submit at: mdpi.com/journal/viruse…
Back at work after the amazing #EMBOvirus18 meeting. Miss me some #phage so I tried to draw one. Happy Monday! __ / \ \ __ / /=\ | | _ | | _ / \ | | / \ / \==/ \
Last speech has ended, last guest have left the lecture room and @EMBOVoM2018 has ended. We will miss you! Thanks! #EMBOvirus18
Really enjoyed all the talks at @EMBOVoM2018, huge thanks to the organizers! Going to miss my new phun phage phriends!! #EMBOvirus18 @godinho_lia @hannimuller
“Happiest moment in life is quick finishing” as #EMBOvirus18 is over now 😢, thank you millions times 👏🏻🎩to @EMBOVoM2018 🇵🇱for this conference in all details. I am proud to be one of phage society in the world ☺️. From now i can’t wait for #EMPOvirus2020
#EMBOVIRUS18 This has been absolutely marvellous conference. It couldn’t have been better. #wow #welldone
And I'm done tweeting #EMBOvirus18
UB- in absence of Holins maybe Gp78 is helping the endolysins to get across the membrane, possibly a chaperone? #EMBOvirus18
SL- off the shelf products still going to be important to treat circulating clinical strains. Also needed to show clinical repeatability and provide proof of efficacy #EMBOvirus18
FINAL INVITED SPEAKER! Urmi Bajpai: functional characterization of LysinA&B from a New Delhi Mycobacteriophage-PDRPxv, which is virulent against M. tuberculosis. LysinA targets peptidoglycan & LysinB targets mycolylarabinogalactase esterase #EMBOvirus18
SL- Sensitivity patterns may shift during treatment. Interested in looking at mixed infections. #EMBOvirus18
SL- one case➡️P.a. infection after lung transplant treated via I.V. route w/AB-PA01, within 6 hours phage product not detectable in serum #EMBOvirus18
SL- released data in January 2018 on use of products through expanded access in 7 patients. Hard to count bacteria in some patients because also on abx. In 1 patient--didn't survive likely bcus already in septic shock #EMBOvirus18
SL- describes 2 phage products AB-SA01 (Staph aureus) & AB-PA01 (Pseud aeruginosa). AB-SA01-in acute pneumonia lung mouse model it reduced CFU as well as vancomycin #EMBOvirus18
JS- test 1000 ticks from 200 geographic areas in UK➡️38% positive by qPCR assay. Trying now to isolate Borrelia phages, but difficult to separate out cus using a rich media #EMBOvirus18
SL- novel challenges for phage--like what is optimal dosing? Can't use normal PK/PD methods used for antibiotics #EMBOvirus18
JS- evaluated qPCR assay vs serological test to diagnose Late LD, which harder to treat than Early LD. 222 LLD samples tested. qPCR yield detects 90% vs serological detects only 25% positive samples. qPCR positively diagnoses 7/14 serological negative ELD samples. #EMBOvirus18
Jinyu Shan from @MarthaClokie lab uses phages to better diagnose Lyme disease and is on the hunt for Borrelia phages. #EMBOvirus18
NT- she summarizes many published studies in Russian patients. There are a good number that don't have good controls 😑 #EMBOvirus18
JS- saw a tight correlation between Borrelia and phage. No positive signals against other bacterial strains, even relapsing fever Borrelia. Validated by spiking experiment. Internal controls used #EMBOvirus18
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Always a pleasure to talk about phages in a Biofilm meeting. A great audience!
Final speaker in the phage session at @DelNAM1 workshop on #biofilms is @azeredo_joana.
We’ve just launched our @BactiVax account. Will be advertising 15 PhD positions in #VaccineResearch soon across 8 EU countries 🇮🇪 🇪🇸 🇧🇪 🇭🇺 🇬🇧 🇮🇹 🇩🇪 🇨🇭 stay tuned! #VaccinesWork
My first attempt at #Inktober 1. Ring
When your bacteria make babies but those babies are actually more like zombies and are technically not alive. #phage
Enjoying Shrewsbury folk festival, fab music and a great atmosphere... and the cherry on the cake I have a mehndi phage 🙂!
Part I of our interview with the inimitable Elizabeth Kutter, The First Lady of #Phage Research, is online now and free to access. Check it out here: ow.ly/gmJR50vxGJs
It’s been really nice, informative and inspiring few days, my very first conference with viruses people. Thanks #EMBOvirus18 you’re special
Thank you Wrocław and @EMBOVoM2018 for a great #EMBOvirus18 meeting! I learned a lot and made quite a few "phriends" who I'll keep in touch with - it was truly an amazing experience. Now I'm off for a few days of rest on my sunny Lisboa ☀️😎!
@EMBOVoM2018 Thank you very much #EMBOvirus18, it is really a great success. Though the conference has ended, but the special issue "Viruses of Microbes V" is still open @Hallison67 . If you are interested in this project, please submit at: mdpi.com/journal/viruse…
Back at work after the amazing #EMBOvirus18 meeting. Miss me some #phage so I tried to draw one. Happy Monday! __ / \ \ __ / /=\ | | _ | | _ / \ | | / \ / \==/ \
Really enjoyed all the talks at @EMBOVoM2018, huge thanks to the organizers! Going to miss my new phun phage phriends!! #EMBOvirus18 @godinho_lia @hannimuller
“Happiest moment in life is quick finishing” as #EMBOvirus18 is over now 😢, thank you millions times 👏🏻🎩to @EMBOVoM2018 🇵🇱for this conference in all details. I am proud to be one of phage society in the world ☺️. From now i can’t wait for #EMPOvirus2020
#EMBOVIRUS18 This has been absolutely marvellous conference. It couldn’t have been better. #wow #welldone
UB- in absence of Holins maybe Gp78 is helping the endolysins to get across the membrane, possibly a chaperone? #EMBOvirus18
Sadly the very rich and enriching #EMBOvirus18 is coming to an end ... the diversity of talks (inspired by the diversity of viruses) made it hard to take a break or even get souvenirs :) maybe this afternoon!
FINAL INVITED SPEAKER! Urmi Bajpai: functional characterization of LysinA&B from a New Delhi Mycobacteriophage-PDRPxv, which is virulent against M. tuberculosis. LysinA targets peptidoglycan & LysinB targets mycolylarabinogalactase esterase #EMBOvirus18
SL- off the shelf products still going to be important to treat circulating clinical strains. Also needed to show clinical repeatability and provide proof of efficacy #EMBOvirus18
SL- released data in January 2018 on use of products through expanded access in 7 patients. Hard to count bacteria in some patients because also on abx. In 1 patient--didn't survive likely bcus already in septic shock #EMBOvirus18
SL- Sensitivity patterns may shift during treatment. Interested in looking at mixed infections. #EMBOvirus18
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