This hit me f*cking hard: a handful of people taught Claude to remember everything they know, and not one of them bothered to show the rest of us how
meanwhile everything you read goes into tabs, bookmarks and chats that never talk to each other
the people building the best AI setups right now are using this, and you can set it up in 20 minutes with Claude and Obsidian:
→ a vault with three folders: raw, wiki, output
→ open it in the Code tab of Claude Desktop
→ let Claude interview you and write its own CLAUDE.md
→ drop one article into raw and tell it to ingest
then open the graph. pages that didn't exist five minutes ago, already wired to each other
one scheduled task and it files everything you save while you sleep. you wake up to a log of what it learned
a week in, you ask one question and Claude connects sources you'd never have put together yourself
keep "using only wiki/" in your questions, or Claude fills the gaps and hands it back as yours
full build in the article below
save it so you don't lose it
this might be my last normal tweet before biotech goes vertical
i'm not a whistleblower. I don't work at Lilly, Novo or any of the big labs
but there is a massive shift happening in human biology right now.
it's sitting in press releases and almost nobody reads them
the last 6 months alone:
- a once-daily pill roughly doubled median survival in metastatic pancreatic cancer (13.2 vs 6.6 months)
- a one-time gene editing infusion cut hereditary angioedema attacks 87%, and 62% of patients stayed attack-free and off all other prevention for 6 months
- a one-time gene edit for cholesterol dropped LDL up to 62%, and it held for over a year
- a personalized mrna vaccine beat keytruda alone in a 1,137 patient melanoma phase 3
- retatrutide hit ~28% weight loss in a phase 3
- an ai-designed drug entered phase 3
- a pill that regrows hair passed its second phase 3
- an immunotherapy that could let some rectal cancer patients skip surgery, chemo and radiation just got fda approved
- a man lived 271 days off dialysis on a pig kidney
- human cells were caught passing chromosome-sized chunks of DNA to their neighbors, and it changes how the neighbors behave
we are on the verge of an era where the human body is a software problem and the update cycle gets shorter everyday
stick around, it's going to get weird
bio/acc
Dwelling about the past is the worst use of energy a human can deploy …
Regret
Dwelling
Complaining
Festering in the past
ALL BAD! Stop 🛑 doing it
It’s over … move on .. stop beating yourself up or blaming someone or something
Moving on … forgiving .. will change your life ‼️❤️
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Anthropic dropped their personal AI agent Claude Duet a few days ago and I'm blown away
Out of all the AI agents, it is the most:
• Intelligent (Opus 5.5)
• Proactive (constant new ideas)
• Friendly (that Claude warmth)
Here is how you get the most out of Duet:
سأقدم مبلغ 5000 دولار، فأنا رجلٌ يفي بوعوده.
(نعم، الأمر حقيقي)
كل ما عليك فعله هو الإعجاب بالمنشور، أو التعليق عليه، وتفعيل التنبيهات.
سيتم الإعلان عن الفائز خلال 48 ساعة.
9-0. NINE STRAIGHT. 🔥🔥🔥
SEE YOU TMRW.
New York Knicks -3.5 (-115) ✅💸
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Miami Dolphins +5.5 (-115) ✅💸
Charlotte Hornets +3.5 (-110)✅💸
Detroit Pistons ML (-112)✅💸
Chicago Bears -2.5 (-127)✅💸
Minnesota Timberwolves +1.5 (-106)✅💸
Detroit Pistons +1.5 (-106)✅💸
Washington Commanders +7.5 (-110)✅💸
🐢
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