Someone just bought $435,000 of CoreWeave, $CRWV, puts betting the stock keeps falling.
Contract: $50 puts expiring Feb. 19, 2027
Size: 649 contracts at about $6.70 each
Swept across exchanges and bought mostly at the ask, a sign of urgency
Breakeven: about $43.30 by expiration
The trade also triggered repeated alerts today.
A machine learning pioneer was asked why AI has not cracked drug discovery. She did not blame the models.
Daphne Koller wrote the textbook a generation of ML researchers learned from and now runs insitro. She says 90% of drugs that enter the clinic fail, and the vast majority fail for a reason that has nothing to do with chemistry. The molecule does exactly what it was designed to do. The mechanism it hits turns out to do nothing for the disease.
Only 22% of diseases have any FDA approved drug at all. She calls that 22% the upper bound of what we understand, not the floor.
Biology's bottleneck is knowing what to aim the model at.
@quxiaoyin China isn't trying to win with one superior model, it's pursuing diffusion. And the US still competes as if a frontier lead is the whole contest. But both can hold at once. What do you think the change should be?
@cochang_eth NFT-GALAXY here,
Just saw your letter. Tried to message but failed. message me if you want to talk.
Changing the listing price of this letter to 1 ETH as proof
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╰┈➤ Read Daphne Koller's "Drug Discovery Has No Magic Wands" on insitro's official Substack: https://t.co/N3MfAN8dac
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