HullemanLab @HullemanLab
A vision research lab leveraging chemical biology, biochemistry, drug discovery, and gene therapy to develop unique approaches for retinal diseases. hulleman-lab.umn.edu Minneapolis, MN Joined April 2021-
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#HappyHolidays from the Hulleman Lab! Our Texas-born #Christmas cactus has been working overtime this year!
Cool to see our work highlighted in the @promega Connections blog. Thanks to Jordan Villanueva for the write up! Check it out below. promegaconnections.com/academic-acces…
Congrats to Nathan Johnson, Ph.D. for securing a VitreoRetinal Surgery Foundation (VRSF) Fellowship to extend his time in the lab!
Welcome to @MPaT_PHCL_UMN rotation students Jillian VanTreeck and Julian Yang. Two full weeks in and already some successful HiBiT edits. It’s great to have their enthusiasm in the lab! #visionscience #ophthalmology
Proud of our first yellow flame plasmid in @Addgene! Request yours while supplies last… addgene.org/192815/
Don’t hit snooze after your parrilla-induced siesta today! Be sure to stop by our #ISER2024 session on small molecule therapies for retinal diseases - Quebracho B 5th Floor starting at 3:30PM. @iserworld
What a difference a day makes - clearly fall in MN, lovely spring (almost summer) weather in Buenos Aires. #ISER2024 has started off with a strong program today. @iserworld
Great to see that our #AMD-related work was recognized by @NEIDirector! Beautiful photo credit: @StefPhDaniel and @pravz2505
Great to see that our #AMD-related work was recognized by @NEIDirector! Beautiful photo credit: @StefPhDaniel and @pravz2505
Exciting news: U of M researchers have discovered a potential new pathway to prevent age-related macular degeneration. Read more from John Hulleman, PhD ➡️: bit.ly/4dLYlrL. #MacularDegeneration | #AMD
#ISER2024 is 2 mo away! Mark your calendars - Yuanyuan Chen @UPMC and I are hosting a session on small molecule therapies for retinal degeneration. Talks by @StefPhDaniel, Liyun Zhang @HopkinsMedicine, Tim Corson @UofTPharmacy, Marco Bassetto @UciCtvr, and yours truly. @iserworld
Very excited to share our recent work just published in @JCI_insight. Low level #GSK3 inhibition via CHIR99021 remodels the #ECM and prevents BLamDs in an early-onset #AMD mouse model. Congrats to Sophie DiCesare on a great paper! @UMNews insight.jci.org/articles/view/…
After dedicating 2+ yrs to the Lab, quantifying ~35,000 microns of Bruch’s memb./basal laminar deposits in TEM images, Antonio Ortega is now a Vivien Thomas PhD Scholar @HopkinsMedicine. Thankful for the opportunity to teach and learn from Ant and excited for his next chapter!
In our latest work, we show that fibulin-3 cysteine mutations present in the human population can severely compromise secretion, affect #MMP2 activity, and trigger #ERstress with implications for human #ECM diseases. @biorxivpreprint @ClinGenResource biorxiv.org/cgi/content/sh…
Happy to announce that we have received a two-year Regenerative Medicine Minnesota grant to develop next-gen tools to better study proteins implicated in age-related macular degeneration (#AMD). @UMNews @umnmedschool #RegenMedMN
Congrats to @StefPhDaniel for receiving a travel grant to attend the #ISER2024 meeting in Argentina. Also, welcome to medical student Nathan Johnson, who secured a summer research fellowship from the University of Minnesota-Duluth. #visionresearch #ophthalmology @iserworld
It's hard to get 7 people in a photobooth. n = 4 for a partially successful whole lab picture. Happy Birthday Antonio!
Over the past month the Hulleman Lab has grown substantially. It's great to welcome Emily Baker, Anna Roovers, Pravallika Kambhampati, and Harkamal Kaur to the team! #visionscience #ophthalmology
An amazing resource @UMNresearch is the access to human donor eyes. Since ~2500 eyes are processed annually by @LionsGiftSight, we took a cool Lab Field Trip to learn about the process and watch a human globe dissection by the talented Sung Lee. #AMD #RPE
Enjoying the cool weather in Belfast prior to the @ISSECsociety Ectopic Calcification meeting hosted by @hervekempf and @Drusen_Lengyel. Looking forward to learning more about mineralization in diseases like #AMD and #PXE

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