John Patrick Stein @JPSwcpmc
Family Physician with great interest in Preventative Cardiology. Looking at the best science to identify risk and treat it prior to stroke and heart attack. johnpatricksteinmd.com St. Louis Joined October 2013-
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Followers559
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Following408
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Evidence is tricky thing... it is good to have some of it before becoming too fixated.
Evidence is tricky thing... it is good to have some of it before becoming too fixated.
"Those who cannot remember the past (or their meds) are condemned to repeat it." George Santayana and then refined later by W. Churchill.
"Those who cannot remember the past (or their meds) are condemned to repeat it." George Santayana and then refined later by W. Churchill.
Gene therapy and genome editing for lipoprotein disorders. #Dyslipidemia #Lipids by the Rosenson ‘s teàm academic.oup.com/eurheartj/arti…
This is a telling and startling graphic. What is the size of the thrombus in a coronary artery that can send one to Heaven or the CCU? The coronary artery lumens are quite small, and a cholesterol-rich plaque rupture or erosion will induce a thrombus. Few recognize how big is the…
What an inspiring 1st day at the #FHFSummit25! 💙 From patient stories & an FH session, to new Lp(a) data from Family Heart — and honoring Dr. Sam Tsimikas (@Lpa_Doc) with the 2025 Pioneer Award. Now on to Day 2 — another day of learning, connection & advocacy in Atlanta!
📉Lower LDL-C for longer is better. The NLA’s new guidance simplifies LDL-C management for adults — helping clinicians & patients improve evidence-based measurement and treatment of LDL-C. Read the guidelines & recommendations: lipidjournal.com/article/S1933-…. @LipidCNS @CBallantyneMD
That is quite an impressive reach! You must have an important message to share to keep our interest!
That is quite an impressive reach! You must have an important message to share to keep our interest!
This sounds eerily similar to what Dr. Allan Sniderman has been preaching for over a decade...better late than never...
This sounds eerily similar to what Dr. Allan Sniderman has been preaching for over a decade...better late than never...
The 2025 @FamilyHeartFdn Global Summit will bring together patients, clinicians, and researchers working to reduce the burden of inherited lipid disorders like familial hypercholesterolemia and elevated Lp(a). This year’s theme, “Catalyzing Collective Action for Lp(a) & FH,”…
To further confuse @JohnKastelein here is new data from STRENGTH showing EPA + DHA reduced MACE in Asian patients. Perhaps due to their IR and TG issues. atherosclerosis-journal.com/article/S0021-… @nationallipid @society_eas @ASPCardio @escardio @atherosociety
The Lp(a) International Taskforce, hosted by @FHEurope & chaired by Prof. Florian Kronenberg, has responded to the EU CV Health Plan consultation. 🫀 Add your voice by Sept 15! 👉 ec.europa.eu/info/law/bette… #CVHealthForAll #FindLpa
Yes Lp(a) concentrations varies by race and ethnicity. First graphic below shows gender and racial differences in US. Also note there can be slight variability in coincentrations over time - women should repeat after menopause
Yes Lp(a) concentrations varies by race and ethnicity. First graphic below shows gender and racial differences in US. Also note there can be slight variability in coincentrations over time - women should repeat after menopause https://t.co/IVtgvb82VD
#lipids #prevention #atherosclerosis #lipoproteins @nationallipid @CMHC_CME @ASPCardio @eas @BCMHeart @Texas_Heart The evolving landscape of targets for lipid lowering: from molecular mechanisms to translational implications pubmed.ncbi.nlm.nih.gov/40911366/
Lp(a) elevated in the setting of adverse pregnancy outcomes - is it the chicken or the egg? @ErinMichos and I review in our new editorial. @UCSDCardiology @UCSDCardFellows @CiccaroneCenter sciencedirect.com/science/articl…
🚨 FDA expands approval of Repatha® (evolocumab) for adults at risk of CV events from uncontrolled LDL-C—even without established CVD. Now approved as monotherapy for HoFH. Important update for clinicians managing FH patients. #KnowFH #KnowHoFH @Amgen prnewswire.com/news-releases/…

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JoAnne Foody, MD, FAC... @FoodyMD
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Viet Le DMSc PA-C FAC... @VietHeartPA
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