RaffaellaSantoroLab @LabSantoro
We study #epigenetics, #chromatin, #3Dgenome organization and the role of #nucleolus in stem cells and cancer santorolab.org University of Zurich Joined September 2019-
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RaffaellaSantoroLab retweeted
AWESOME CONFERENCE ALERT!! I had an absolute blast at the Fusion “Genome Regulation Through RNA” meeting back in 2024, and psyched to see its upcoming return! Let’s geek out about all things Chromatin and RNA together, in Cancun! Talk abstract deadline: 10/17 Details👇
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RaffaellaSantoroLab retweeted
Excited to share another new preprint from our lab in which we developed a cluster-based phasing strategy using long read nano-NOMe-seq data to link distinct CTCF binding states—captured at the single molecule level—to the transcriptional status of genes: biorxiv.org/content/10.110…
RaffaellaSantoroLab retweeted
Excited to share our new preprint:
RaffaellaSantoroLab retweeted
Our work "Aquarius helicase facilitates HIV-1 integration into R-loop enriched genomic regions," is out in @NatureMicrobiol nature.com/articles/s4156…
RaffaellaSantoroLab retweeted
Happy to share our work on how chromatin organization is established for the first time in early mouse embryos, in part via interplay with remarkable hypertranscription. Marvelous work by Guang Yu, Kai Xu, Weikun Xia and Ke Zhang! nature.com/articles/s4158…
RaffaellaSantoroLab retweeted
Join our lab @CIBIO_Trento to uncover how epigenetic mechanisms enable disseminated tumor cells to survive & reawaken during metastasis. 💡 Cutting-edge: CRISPR screens, single cell epigenomics. 📍 Apply now: [semm.it/education/appl…] #PhDposition #Cancer #Chromatin
RaffaellaSantoroLab retweeted
The molecular basis of lamin-specific chromatin interactions nature.com/articles/s4159…
RaffaellaSantoroLab retweeted
Explore RNA's role in epigenetics, DNA repair, transcription & genome organisation - directly with leaders from academia & industry at #GenReg26! Remaining talks will be filled from submissions - register & submit by 04 Sep 2025 to join us in Mexico, March 2026🇲🇽 Speakers,…
RaffaellaSantoroLab retweeted
Excited that our nucleolus mapping paper just came out today in Nature! Truly an amazing study from even more amazing due of @sofiquinodoz & @jiang_lifei w/ @LafontaineLab & Sebastian Klinge and other fantastic co-authors nature.com/articles/s4158…
Excited that our nucleolus mapping paper just came out today in Nature! Truly an amazing study from even more amazing due of @sofiquinodoz & @jiang_lifei w/ @LafontaineLab & Sebastian Klinge and other fantastic co-authors nature.com/articles/s4158…
RaffaellaSantoroLab retweeted
Il videoclip più condiviso della storia della televisione italiana, sì, conosco. #TecheTecheTe
RaffaellaSantoroLab retweeted
Hello RNA World! Ever wonder what's "talking to" your favorite transcript, but were too scared to ask? In our review in @CellReports, @FKHM and I highlight new RNA-focused tools for discovering RNA interactions across organizational scales. Checkit! tinyurl.com/ydn6e3ac
RaffaellaSantoroLab retweeted
The nucleolar granular component mediates genome-nucleolus interactions and establishes their repressive chromatin states dlvr.it/TLCFdR
RaffaellaSantoroLab retweeted
Read the latest issue: cell.com/molecular-cell…
RaffaellaSantoroLab retweeted
Isogenic comparison of Airn and Xist reveals core principles of Polycomb recruitment by lncRNAs dlvr.it/TJjsx8
Very excited to share our latest work in @MolecularCell showing NPM1 stabilizing the association of nucleolus associated domains (NADs) and recruiting G9a to establish their repressive chromatin states. sciencedirect.com/science/articl…
RaffaellaSantoroLab retweeted
Tumor-associated zinc finger CTCF mutations which selectively alter its DNA-binding specificity have been reported for the first time by Galina Filippova et. al. almost 25 years ago: pubmed.ncbi.nlm.nih.gov/11782357/
Tumor-associated zinc finger CTCF mutations which selectively alter its DNA-binding specificity have been reported for the first time by Galina Filippova et. al. almost 25 years ago: pubmed.ncbi.nlm.nih.gov/11782357/ https://t.co/ZBuaMlw4x2
RaffaellaSantoroLab retweeted
Our lab has identified a new epigenetic mechanism and a druggable target in #HFpEF. Extremely thankful to my amazing team and our fantastic collaborators! @CircRes @UZH_en @Unispital_USZ @CTECresearch @PaneniLab ahajournals.org/doi/10.1161/CI…
RaffaellaSantoroLab retweeted
Excited to share our recent paper in Cell Genomics on CTCF mutations!
RaffaellaSantoroLab retweeted
Memento
RaffaellaSantoroLab retweeted
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