Shixian Lin @Linlab_ZJU
Chemical Biologist and Synthetic Biologist; Associate Professor at Life Sciences Institute Zhejiang University person.zju.edu.cn/en/0017079 Hangzhou Joined November 2015-
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It took 7.5 years, but my first lab project is officially out! We develop an approach to identify the liver nascent proteome, especially membrane proteins, under various pathophysiological conditions, revealing key regulators involved in hepatic steatosis. nature.com/articles/s4146…
Thank you🥰. Having the opportunity to publish in @ACSCentSci is a wonderful and very memorable experience.
Thank you🥰. Having the opportunity to publish in @ACSCentSci is a wonderful and very memorable experience.
Check out our work in @ACSCentSci. We have developed a virtual noncanonical amino acid (ncAA) screener that allows evaluation of the genetic encodability of designed ncAAs prior to chemical synthesis. pubs.acs.org/doi/10.1021/ac…
It's great to see this review online @ACSChemRev. Many thanks to the collaborators, reviewers, and organizers of this synthetic biology review @syntheticbiology. We hope that this review will be useful for researchers interested in protein lipidation. pubs.acs.org/doi/10.1021/ac…
Thank you for covering our study.🥰 @TheScientistLLC @KLNahas
Thank you for covering our study.🥰 @TheScientistLLC @KLNahas
Terrific idea that can activate different reactive probes with tunable radical half-lives corresponding to different distance scales.
Terrific idea that can activate different reactive probes with tunable radical half-lives corresponding to different distance scales.
Well Deserved! Huge Congratulations!
Genetically encoding negatively charged lysine PTMs succinylation/glutarylation and studying their funcional roles! Great team effort by first authors @ML_Jokisch and @Maria_Weyh! Congrats @Maria_Weyh @ML_Jokisch @MaxFottner and Anh! 🥳🤩🙌👨🔬🧑🔬 @klanglab nature.com/articles/s4155…
Phenomenal new reactions, new oxaziridine reagents, and their application in the discovery of functional tryptophan interactions. 👍👍👏👏 @christhechang @Toste_Group nature.com/articles/s4158…
This chemical activation of a genetically encoded caged-tryptophan (Trp-CAGE) strategy enables precise activation of the Trp of interest underlying diverse important molecular interactions, such as hydrophobic interactions, polar interactions, and π interactions. @NatureChemistry
Thrilled to share our collaboration work with Peng and @fanxy03 on @NatureChemistry. With a new bioorthogonal reaction, the chimeric translation system, and a new computer algorithm, we can cage and decage Trp on virtually any protein in living cells. nature.com/articles/s4155…
Happy to share that I have been promoted to Associate Professor with tenure. My sincere thanks to all the amazing colleagues, trainees, mentors, and friends over the years.❤️
We got a story, and it’s electric! 🔌⚡️ rdcu.be/dth70 Can electrocatalysis be used to precisely modify a protein? Yes! Happy to finally share this work led by @conor_loynd and @SinghaSoumya. A 🧵 #ProteinElectrochemistry #NSFfunded
🎁Interested in reading more about the study? Here is the N&Vs article written by Jennifer J. Kohler and Mary W. N. Burns: 👉🏻rdcu.be/drQk0 nature.com/articles/s4155…
Our first study of the biological function of protein #OGlcNAcylation #PhaseSeparation, with more interesting findings coming soon. 🤞🤞
Our first study of the biological function of protein #OGlcNAcylation #PhaseSeparation, with more interesting findings coming soon. 🤞🤞
It is our great pleasure to announce that Christopher Chang @christhechang has joined @PrincetonChem as the Edward and Virginia Taylor Professor of Bioorganic Chemistry. Welcome, Chris, we are thrilled to have you! Read here: bit.ly/49JJsV4
It is our great pleasure to announce that Michelle Chang has joined @PrincetonChem as the A. Barton Hepburn Professor of Chemistry. Welcome, Michelle, we are thrilled to have you. Read here: bit.ly/3R69meh

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