Matthew Pendleton @Matt__Pendleton
All things structural: structural biophysics, SVs, chromatin structure, structure of adaptive immune intelligence. Pevzner F3. Arizona, USA Joined February 2018-
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V for Vendetta was not intended to be an instruction manual.
V for Vendetta was not intended to be an instruction manual.
my Romanian Uber driver was telling me the other day that he had far more freedom under Ceausescu than he has in the UK ...
DT: #COVID19 work has extended beyond the virus itself to host response, e.g. using adaptive sampling to target host genome of immunised individual + single cell transcriptomics, allowing assignation of antibody transcripts to personalised immune locus assembly #nanoporeconf
Research from the tenOever lab on #SARSCoV2 is showcased in this week’s @NewYorker. I could not be more proud of them. Shoutout to @daisyhoagz @rsmsllr @DBM003 @skyleruhl @BenjaminNilsson & all those not on Twitter newyorker.com/magazine/2020/…
Amazing work by the #T2T consortium led by @khmiga and @aphillippy. It was an honor to be part of the team! Check out how we were able to probe methylation *inside* the human centromere. Now onto the next 23 :) nature.com/articles/s4158…
More data suggesting that early treatment of IFN-I/-III may help in preventing #COVID19. Impaired type I interferon activity and inflammatory responses in severe COVID-19 patients science.sciencemag.org/content/early/…
Latest preprint from us. Immunological Mapping of Multisystem Inflammatory Syndrome in Children (MIS-C). @SinaiImmunol powerhouse team effort. Thank you. @IcahnMountSinai @MountSinaiNYC @SinaiGenetics @MindichCHDI . doi.org/10.1101/2020.0…
Very impactful march around our town tonight. Any concerns for safety melted away into a deep sense of community and compassion for all. Hopefully for real progress for the first time since Nov ‘16. #BlackLivesMattter
This quarantine has clearly gone on too long.
This quarantine has clearly gone on too long.
Oxford @nanopore announces $59.2M in new capital bit.ly/2AZAuXP
Tired of looking at SV calls and thinking "WHY was this called, it's TERRIBLE?" Us too So we trained a model. Gets rid of 47% of FPs. Keeps 97% of TP. Quick writeup here biorxiv.org/content/10.110… Full paper w/ major samplot upgrades soon github.com/ryanlayer/samp… 1/4
1) I wanted share some data from a manuscript that just wen online at medrxiv.org/content/10.110…. This was spearheaded by the fantastic Dr. Ania Wajnberg in collaboration with many parts of the Mount Sinai Hospital and Icahn School of Medicine.
Release v1.0.0 · nanoporetech/medaka · GitHub github.com/nanoporetech/m…
#COVID19 in 🇺🇸| While new cases show a downward trend in NY metropolitan area, it is arguably rising in the U.S. as a whole. Interesting pattern in reporting of new cases though: peaks towards end of workweek (Thu/Fri)🧐 nytimes.com/2020/05/05/us/…
Excellent review of human immune responses to coronaviruses! The best one I found so far. I already cited it 👍😀 medrxiv.org/content/10.110…
p-hacking: when a child asks multiple parents for permission until they get a positive result.
The tenOever lab is working around the clock to learn more about the biology of #COVID19. Tomorrow we upload 150+ RNA-Seq data sets to NCBI GEO.
With heavy hearts we share that James Taylor, Professor of Biology and Professor of Computer Science, died on Thursday, April 2. He was a trailblazer in computational biology and genomics research. His loss is devastating at Hopkins and around the globe. bit.ly/2wbE92R

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Jess Davies @jldavies16
290 Followers 539 Following Science is just awesome 🤓🙌. All opinions are my own, except the previous - which is clearly a fact. Once a scientist, always a scientist! She/her/they.
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355 Followers 1K Following All opinions my own. Director of Outreach and Education for @cegs_ica. Science. Art. Life. Artist profile is @thisyearning
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90 Followers 248 Following Firefighter. Transposons. Ageing. Phd student.
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Prof. Dr. Benhur Lee,... @VirusWhisperer
34K Followers 953 Following Viruses are the best cell biologists! Emerging viruses | Mentor |🏳️🌈 | #LoveVirology #STEM #ViralLeeLab
Aaron Viny @TheDoctorIsVin
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International SciComm... @IScicommunity
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66K Followers 9K Following 🌍Direct DNA/RNA analysis for anyone, anywhere 🧬Short to ultra-long reads in real-time for rapid insights 🔬Products for research use only
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