Neochoritis Lab @NeochoritisLab
We have a strong focus on synthetic organic chemistry and the basic tool of our strategy are Multi-Component Reactions (MCRs). #neolab chemistry.uoc.gr/neochoritis/ University of Crete Joined May 2022-
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🚨New paper out in Nature Communications! Scaffold hopping + MCR chemistry to design non-covalent molecular glues for the 14-3-3/ERα complex. A step forward in PPI-targeting drug discovery @University of SanFrancisco! @NeochoritisLab @NatureComms @UOC_gr nature.com/articles/s4146…
How you evolve an imaging agent into a potent therapeutic? Thanks everybody for this fruiful collaboration! doi.org/10.1002/chem.2… @UOC_gr @NeochoritisLab @ChemEurope @ChemEurJ #MCRs
Proxybinders! Glues and more!!! Tnx to the hard work of Marios and Michalis! @UOC_gr @NeochoritisLab #MCRs #helmedchem2025
#EurJOC Diving into the Shielding Surfaces: Construction of Atropisomeric Axes via Multicomponent Reactions (Constantinos G. Neochoritis and co-workers) @UOC_gr @kneochor @NeochoritisLab #openaccess 🔓 onlinelibrary.wiley.com/doi/10.1002/ej…
How can we exploit CH-π interactions and shielding surfaces to tweak conformations of known scaffolds? Thanks everyone for this work! …mistry-europe.onlinelibrary.wiley.com/doi/10.1002/ej… @EurJOC @ChemEurope @NeochoritisLab @UOC_gr @ELIDEK_HFRI #MCRs #Neolab
Interrupting the route of known reactions can lead to novel chemotypes. By installing the oxo and acid functionalities on the same carbon, interrupted Ugi and Passerini reactions were discovered! doi.org/10.1021/acs.or… @NeochoritisLab @ELIDEK_HFRI @ACSPublications @JOC_OL #MCRs
C1 annulations are never outdated! Thanks everybody for this smart way of utilizing formamide in a sustainable way! 10.3762/bjoc.21.13 @NeochoritisLab @UOC_gr @EmpireikionIdryma #MCRs #Neolab
Very glad to be hosted and present our work on MCRs at the National Hellenic Research Foundation!! @NeochoritisLab @ELIDEK_HFRI @UOC_gr #MCRs
Let us share some moments from last week in the 23rd Panhellenic Chemistry Conference!
We were very happy to be part of the 23rd Panhellenic Chemistry Conference, 2024. Our group thrived with 3 oral presentations, 2 flash poster presentations and 2 poster attendances. Looking forward to many more opportunities like this!
We are obligated to inform you about the achievements of @UOC_gr in the 3rd day of PCC 2024! Congratulations to Prof. M. Orfanopoulos for being awarded for his lifelong achievements in organic chemistry. Also congratulations to Prof. G. Vassilikogiannakis for his amazing lecture!
The 23rd Panhellenic Chemistry Conference have just started! #neolab #chemistry #ath #PCC2024
Not because she’s a member of our, but Paria Anastasiou just delivered a great Oral Communication at the EFMC-ISMC 2024! Congratulations! 🎉 @kneochor @EuroMedChem @UOC_gr #neolab #EFMCISMC24 #uoc
The star of our lab is beginning her oral presentation! 💫
A round of applause to Marios Zingiridis from our lab for delivering a flash poster presentation and engaging in poster session at EFMC-ISMC 2024! @EuroMedChem @kneochor @MichelleArkin @mark_kons #EFMCISMC24 #neolab #Rome
Day 3 of EFMC-ISMC 2024! We have started with a great presentation from a partner of our lab Prof. Luc Bunsveld! #EFMCISMC2024 #Rome #neolab
High Rotational Barrier Atropisomers (Constantinos G. Neochoritis @kneochor and co-workers @NeochoritisLab at @uoc.gr) #OpenAccess onlinelibrary.wiley.com/doi/10.1002/ch…
Two members of our group are attending EFMC-ISMC 2024 with an oral communication and a flash poster presentation! Looking forward to connecting and sharing insights! @kneochor #neolab #EFMCISMC24 #September2024 #medchem
Unraveling the Potential of Cyclic N-Sulfonyl Ketimines in the MCR Universe (Constantinos G. Neochoritis and co-workers) @UOC_gr @kneochor @NeochoritisLab #openaccess onlinelibrary.wiley.com/doi/10.1002/ej…

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