Neurons Guide Decisions by Suppressing Alternatives Scientists have mapped out the neural interactions that underpin decision-making processes in the brain. This study illustrates how making a choice activates specific groups of neurons, which in turn suppress alternative decision pathways, thus reinforcing the chosen option. The research delves into the posterior parietal cortex's significant role, an area critical for integrating sensory information to facilitate navigational decisions. By observing mice within a virtual reality maze and analyzing the structural connections between neurons, the team discovered that excitatory neurons associated with a particular decision direction activate inhibitory neurons to dampen the activity of neurons linked to the opposite choice. This neural mechanism could be crucial for maintaining a decision, potentially offering new insights into the neural basis of decision-making and its implications for mental health disorders. 1/3
Neurons Guide Decisions by Suppressing Alternatives Researchers uncover how neuron groups guide decisions by suppressing alternate pathways, a key insight into the brain's decision-making process. This study paves the way for understanding mental health disorders and the complex neural dynamics of choice. neurosciencenews.com/decision-makin… 2/3
“Synaptic wiring motifs in posterior parietal cortex support decision-making” by Wei-Chung Allen Lee et al. Nature nature.com/articles/s4158… 3/3
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