16th Key Symposium: The Origin of Cancer 2019 @OriginCancer19
8 - 10 September 2019, Stochholm, Sweden. Keynote speakers: Hans Clevers, John Dick, Sir Mike Stratton originofcancer2019.com Stockholm, Sweden Joined August 2019-
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Brief animation of gut stem cells at work. In the center is a villus. 6-8 crypts surround its base. Stem cells reside at the bottom of the crypts of Lieberkuehn. It only take 4-5 days for stem cell daughters to complete their journey to villus tip, after which they sadly die
My lab has an open PhD position! Are you curious to know how human primary cells interact with their environment by exerting forces and reading biomechanical cues, and how it all ties into decisions of cell fate? Please RT and contact me for further details!
Thank you @OriginCancer19 What a deluge of ideas, data, and top notch presentations on #organoid models, normal tissue/#stemcell biology, and #Cancerinitiation. Will take a while to digest it all. Extra treat to see #bladdercancer represented by Michael Shen
THANK YOU @JInternMed and @vetenskapsakad for hosting a spectacular meeting @OriginCancer19 '16th Key symposium: The Origin of Cancer 2019' @OriginCancer19 #orican2019 #cancer
Increased oleic acid/reducing agents in the lymph promote ferroptosis resistance + increased survival of metastasizing melanoma cells, elegantly shown by @sjmorrison #orican2019 #Melanoma #metastasis
Why do melanoma cells metastasize through lymphatics? @sjmorrison shows that lower oxidative stress in lymph protects melanoma cells! 👏👏 #orican2019 #melanoma #metastsis
Sean Morrison @sjmorrison concludes an exceptional scientific program @OriginCancer19 talking about “The metabolic regulation of cancer progression” #orican2019 #Cancer
Charles Sawyers @CharlesSawyers reveals studies on “Lineage Plasticity in Prostate Cancer” @OriginCancer19 #orican2019 #ProstateCancer
It is our pleasure to host John Dick @PMResearch_UHN who is giving this evening's keynote lecture @OriginCancer19: “Tracking the arc of AML and B-ALL from the cell of origin to the origin of relapse in a single blood sample” #orican2019 #Cancer
cfDNA methylation analysis can distinguish stage I (!) renal cell carcinoma and even discriminate between different cancer subtypes! Ground-breaking work from @decarvalho_lab! 👏👏 #orican2019 #renalcarcinoma #glioblastoma #cancer
Pioneering work recapitulated by @decarvalho_lab, demonstrating that cfDNA methylome analysis allows highly sensitive detection of tumor cfDNA in early stage tumors. Incredibly sensitive method! #orican2019 #cancer #methylome nature.com/articles/s4158…
Daniel De Carvalho @decarvalho_lab talks about ‘Ultra-sensitive Tumor Detection and Classification using Methylome Analysis of Plasma cfDNA’ #orican2019 #cancer #methylome
Thomas Würdinger @amsterdamumc: Tumor-educated platelets are a rich source of tumor-associated extracellular vesicles and genetic material. Can thromboSeq be used for organ-of-origin test, platelets as source for pan-cancer testing? @OriginCancer19 #orican2019 #cancer #platelets
We warmly welcome our next speaker @OriginCancer19: Thomas Würdinger @amsterdamumc ‘Tumor-educated platelets for the detection of cancer’ #orican2019 #cancer
Blood aging can be projected on other tissues. Great talk from energetic Liran Shlush @WeizmannScience #orican2019 #cancer #leukemia
Liran Shlush @weizmann on leukemia evolution: Most common deletion in leukemia occurs due to microhomology-mediated end joining (MMEJ), explanation for mutational hotspot! #orican2019 #cancer #leukemia

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