Pascal Sturmfels @PascalSturmfels
PhD student at @uwcse + @UWproteindesign working on machine learning for protein design, protein language models, etc. psturmfels.github.io Seattle, WA Joined December 2019-
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Even though I probably spent more time in the lab playing chess than doing research, for some reason they gave me a PhD 🥳🥳
Even though I probably spent more time in the lab playing chess than doing research, for some reason they gave me a PhD 🥳🥳
That's my designed protein on the cover of Science! Achievement unlocked!
That's my designed protein on the cover of Science! Achievement unlocked!
Researchers in Science present a next-generation protein structure prediction and design tool, #RoseTTAFold All-Atom, that can accept a wide range of ligands and covalent amino acid modifications. Learn more in this week's issue: scim.ag/6Ea
Specifying the input for cofolding models just got easier with my new gradio component "gradio_cofoldinginput". Try it here to generate inputs for RoseTTAfold2 All Atom predictions including covalent modifications: huggingface.co/spaces/simondu…
Specifying the input for cofolding models just got easier with my new gradio component "gradio_cofoldinginput". Try it here to generate inputs for RoseTTAfold2 All Atom predictions including covalent modifications: huggingface.co/spaces/simondu…
Super excited to share our paper “Design of amyloidogenic peptide traps” is out now! 🧠 nature.com/articles/s4158… Special thanks to @eaandrzejewska , Danny Sahtoe and David Baker
We’re excited to share our preprint where we show, for the first time, the atomically accurate design of VHH antibodies!
🧵(1/7) Excited to share that our work, EquiformerV2, has been accepted to #ICLR2024. EquiformerV2 is the state-of-the-art on large-scale atomistic benchmarks -- OC20, OC22, AdsorbML, and ODAC23. Joint work with @bwood_m, @abhshkdz from @OpenCatalyst and @tesssmidt Paper:…
AlphaFold2 and RoseTTAFold are limited to predicting the 3D structure of proteins. A new all-atom method models complete biomolecular assemblies, including proteins, nucleic acids, small molecules, metals, and covalent modifications. #NBThighlight science.org/doi/10.1126/sc…
Our work on modeling and designing biomolecular assemblies is now in @ScienceMagazine. science.org/doi/10.1126/sc… RFAA Code: github.com/baker-laborato… RFdiffusionAA Code: github.com/baker-laborato…
Excited to finally be able to share our ICLR work critically analyzing the capacity of deep learning docking methods to generalize and how to improve this (spoiler scaling, augmentation and RL)! With this, we release a new significantly improved version of DiffDock! A thread! 🧵
Our paper using ProteinMPNN redesign for improved properties is up on JACS! Huge thanks to Reyes, @ikalvet, Sam, and many others for their work. Shout out to @JustasDauparas for developing such a groundbreaking (and versatile!) tool. @UWproteindesign pubs.acs.org/doi/full/10.10…
looking for interns for two projects next summer, come work with me, @nc_frey and the rest of the @PrescientDesign team applying bleeding edge machine learning to fascinating biological data!
looking for interns for two projects next summer, come work with me, @nc_frey and the rest of the @PrescientDesign team applying bleeding edge machine learning to fascinating biological data!
Monday 11am Reading group: RosettaFold all-atom! biorxiv.org/content/10.110… Let us discuss with @r_krishna3 what protein design niceties we can achieve with this. And also the AlphaFold all-atom "glimpse" :) Join on Zoom at 11am ET / 4pm UTC / 5pm CET: portal.valencelabs.com/logg
Soo, this is a big one :) On Nov 20 we will have RosettaFold all-atom in the reading group with @r_krishna3! Quite amazing protein design capabilities. But that is my naive evaluation - join us and let's discuss and hear your insights! Sign up here: portal.valencelabs.com/logg
Thrilled to announce the opening of the Srivatsan Lab (srivatsan-lab.com) at the @fredhutch. The lab will be building new sequencing technologies to understand how our cells and bodies form over the course of development.
Thrilled to announce the opening of the Srivatsan Lab (srivatsan-lab.com) at the @fredhutch. The lab will be building new sequencing technologies to understand how our cells and bodies form over the course of development.
RFdiffusionAA generating a small molecule binding protein against an experimental FXIa inhibitor (OQO), a ligand which is significantly different than any in its training dataset.
RFdiffusionAA generating a small molecule binding protein against an experimental FXIa inhibitor (OQO), a ligand which is significantly different than any in its training dataset. https://t.co/JyHKu2Jylf
RoseTTAFold updated to be All-Atom... biological assemblies containing proteins, nucleic acids, small molecules, metals, and covalent modifications ... and diffusion🤯biorxiv.org/content/10.110…
All-atom version of RoseTTAFold looks quite exciting! biorxiv.org/content/10.110…
We made RoseTTAFold that predicts everything in the PDB, not just proteins, the used it to make RFDiffusion that generates ligand-binding proteins, including a 10nM binder of digoxigenin. See @r_krishna3's thread for details.
We made RoseTTAFold that predicts everything in the PDB, not just proteins, the used it to make RFDiffusion that generates ligand-binding proteins, including a 10nM binder of digoxigenin. See @r_krishna3's thread for details.
Very excited to share RoseTTAFold All-Atom and RFdiffusion All-Atom, methods for structure prediction and design of biomolecular assemblies! biorxiv.org/content/10.110… 1/n
Sergey Ovchinnikov @sokrypton
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Kevin K. Yang 楊凱�... @KevinKaichuang
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David Juergens @DaveJuergens
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Noelia Ferruz @ferruz_noelia
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Basile Wicky @BasileWicky
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Ellen Zhong @ZhongingAlong
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Jue Wang @jueseph
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Lior Pachter @lpachter
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Roshan Rao @proteinrosh
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Institute for Protein... @UWproteindesign
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Alex Chu @alexechu_
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Phil Leung @definitelyphil
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Jacob Schreiber @jmschreiber91
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Dr Chris Thorpe @drchristhorpe
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Jason Zhaoxing Zhang @jasonzxzhang
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Jinwoo Leem @ideasbyjin
1K Followers 619 Following ML research @IsomorphicLabs prev: @alchemabtx, @benevolent_ai, @OPIGlets. Antibodies, LLMs, structure prediction. 🇨🇦🇬🇧🇰🇷 Tweets=my views.
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Taufiq Rahman @RahmanLab
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Michelle Parker @Michel1688
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CTGCT @_CTGCT_
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Kanak Raj @kanak8278
31 Followers 422 Following Opinions are my own, presented with the help of LLMs.
Saacnicteh Toledo-Pat... @SaacNicteh
649 Followers 1K Following Principal Investigator | Buribushi Fellow @OISTedu working on Molecular Bioengineering & Evolution, @MaxPlanckAlumni, 🇲🇽🇩🇪🇯🇵🏳️🌈 🏳️
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rany @ray_rain_sky
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Sumus INVESTIGATORES,... @didactist
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Jose Bustamante S (he... @jos3bustamant3
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Pat Erickson 🧪⚗�... @ShamokinChemist
56 Followers 119 Following Protein Scientist. My views, likes, Tweets, and opinions are my own and not associated with my employer.
Mark Neumann @MarkNeumannnn
3K Followers 2K Following Head of ML at Orbital Materials. BC: Research/Eng at @allenai_org
Tolerance @Tolerance942207
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Chris Myers 💻🧬�... @bayouphysicist
3K Followers 7K Following Professor Physics/Chemical Biophysics💻🧬☕ 🌇 @fordhamnyc 🎓: @riceuniversity🦉 @bcmhouston Formerly: @NYUniversity ⋒ @UmBiophys〽@UTMBhealth
Gulam Sarwar Chuwdhur... @GSChuwdhury
112 Followers 1K Following Interest includes single-cell analysis, immunology, etc. Research Assistant in Bioinformatics, Department of Clinical Oncology, The University of Hong Kong.
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Premraj Thakur @PremrajThakur8
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Ruidong Wu @RuidongWu
215 Followers 545 Following PhD student at @MIT_CSAIL. Prev: @HelixonBio @UofIllinois @Tsinghua_Uni.
Michael Bronstein @mmbronstein
54K Followers 7K Following #DeepMind Professor of #AI @UniofOxford / Director #AITHYRA / Chief Scientist @vant_ai / https://t.co/kZpGpDzYeV (opinions are mine) 🤖🧪🧬🎶🐎
Kristian Frandsen �... @KrFrandsen
971 Followers 4K Following Researcher @DTUbioengineer Enzyme Discovery | Guest researcher @cpsc_ucph @KU_PLEN | former @HOPE_NNF and #INRAE @BBF_lab | #CAZymes #cryoEM #Engineering #AI
Chirag Lakhani @cmlakhan
564 Followers 4K Following Currently: Staff Scientist @nygenome in the @david_a_knowles lab. Previously: @HarvardDBMI Postdoctoral Research Fellow in @chiragjp lab https://t.co/APTLHsivM2
Hudson Kalmans @HKalmans
84 Followers 1K Following BAKER LAB @UWproteindesign IT DOESNT GET BETTER THAN THIS
Varela @dvarelaTW
211 Followers 3K Following protein design, art, python, jokes, artificial intelligence, cinema... you can really expect everything here. (Spanish/English)
Chase Armer @ChaseArmer
234 Followers 460 Following PhD @ Columbia University | 2x Synbio Founder | Protein Engineering Tournament | Combining AI with cloud labs to build self-driving systems for science
Rajan Kumar Kharwar @rajanKumarkhar8
731 Followers 6K Following PhD Candidate @GroupMarek | Schulich Faculty of Chemistry | Technion
Theo Jalabert @theo_jala
170 Followers 273 Following product engineer @adaptyvbio - building software for protein design
Xiaoya Li @xxiaoyali_
1 Followers 213 Following
Davian Ho @iceindavain
186 Followers 2K Following
Mike Ge @mikefzge
244 Followers 366 Following PGY-4 @UofTanesthesia, MD '22 @McMasterU, and BSc '19 @westernuBiochem.
Alireza Hashemi @AlirezaHasheml
9 Followers 139 Following
lili @lili04990164
1 Followers 175 Following
sarrah @AgaRosegirl
43 Followers 660 Following
Bingxu Liu @BingxuL
678 Followers 1K Following Postdoc @UW IPD David Baker group. PhD @mit bio, Darrell Irvine lab and Nir Hacohen lab.
Paul Lourdu Xavier @PaulLXavier
1K Followers 5K Following PhD Scholar, Max-Planck Institute for the Structure and Dynamics of Matter, CFEL-DESY & EuXFEL | Previous: NYU; Stanford University; SLAC; IIT Madras; UoM |
Sergey Ovchinnikov @sokrypton
16K Followers 4K Following Scientist, Assistant Professor @MITBiology, #FirstGen, ProteinBERTologist, 🇺🇦 No Human is illegal. Moving to: https://t.co/sow6IRD3jj
Kevin K. Yang 楊凱�... @KevinKaichuang
21K Followers 6K Following Principal Researcher in BioML @MSFTResearch (@MSRNE). He/him/他. 🇹🇼
David Juergens @DaveJuergens
3K Followers 2K Following Machine learning for molecular design. Currently: Postdoc @StanfordUChem @mtzlab. PhD @UWMolES @UWproteindesign. B.S. @UWChemE
Anshul Kundaje (anshu... @anshulkundaje
27K Followers 3K Following Federally funded academic research is the innovation engine of the US economy. Reform is welcome. Destruction will have long term consequences.
Tom Sercu @TomSercu
2K Followers 756 Following Building @evoscaleai - Frontier AI for biology. Ex-Meta FAIR, Ex-IBM Research. Alum @NYU, @ugent.
Noelia Ferruz @ferruz_noelia
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Generate:Biomedicines @generate_biomed
6K Followers 137 Following As pioneers in generative biology, we're revolutionizing the way biotherapeutics are discovered and developed.
Alex Rives @alexrives
10K Followers 906 Following AI for scientific discovery. Broad and MIT. Chief scientist at @EvoscaleAI and founder and scientific director of the ESM project previously @Meta.
Basile Wicky @BasileWicky
1K Followers 424 Following Protein design & synthetic biology • Asst. prof. @ETH_BSSE
Ellen Zhong @ZhongingAlong
8K Followers 883 Following Assistant Professor @PrincetonCS. #ai4science #proteins247 #cryoem #cryodrgn ❄️🐉 Prev: @MIT @DeepMind @DEShawResearch. Currently moonlighting @generate_biomed.
MLSB (in San Diego + ... @workshopmlsb
2K Followers 0 Following Machine Learning in Structural Biology workshop co-located with NeurIPS 2025 & at EurIPS 2025. Dec 7. San Diego, CA
Joseph Watson @_JosephWatson
3K Followers 97 Following Co-Founder @ Xaira Therapeutics Former Baker Lab PostDoc at @UWproteindesign. Interested in generative modelling for molecular design. Views my own.
Jue Wang @jueseph
2K Followers 759 Following Research scientist @googledeepmind. Formerly @UWproteindesign @ginkgo @HMS_SysBio.
Lior Pachter @lpachter
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AI at Meta @AIatMeta
717K Followers 288 Following Together with the AI community, we are pushing the boundaries of what’s possible through open science to create a more connected world.
Institute for Protein... @UWproteindesign
17K Followers 628 Following We create proteins that solve challenges in medicine, technology & sustainability 🟡 2024 Nobel in Chemistry 📍@UWMedicine — https://t.co/1PR2DtKdeB
Alex Chu @alexechu_
2K Followers 747 Following Deep learning & protein design. @googledeepmind PhD @Stanford
Michael Bronstein @mmbronstein
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Mike Ge @mikefzge
244 Followers 366 Following PGY-4 @UofTanesthesia, MD '22 @McMasterU, and BSc '19 @westernuBiochem.
Christopher Morris @chrsmrrs
2K Followers 114 Following @RWTH. Previously, @Mila_Quebec, @mcgillu, @polymtl, and @TU_Dortmund. Working on learning with graphs and ML for combinatorial optimization.
Alex Morehead (何聪... @MoreheadAlex
801 Followers 1K Following Hopper Postdoctoral Fellow @BerkeleyLab. Prev: #MachineLearning & #CompBio PhD @Mizzou; Research Intern @ Profluent & Absci. #DeepLearning & #GenerativeModels.
Andrew Hunt @Andrew_C_Hunt
346 Followers 446 Following #protein enthusiast and #cellfree evangelist | @newmexicotech to @nu_chbe to @UWproteindesign | Team lead EBRC In Translation Podcast
Ian Haydon @ichaydon
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Luca Naef @NaefLuca
2K Followers 1K Following Co-Founder & CTO, @vant_ai Forbes 30u30 but won't go to jail | prev. ETH Zurich Stanford McKinsey AI x Bio/Chem. vi/vim
Russell Zhang Kunes @russell_kunes
529 Followers 2K Following Now a quantitative researcher at a hedge fund. Previously worked in computational biology & bioinformatics.
Yang Hsia @yhsia_ipd
383 Followers 119 Following Research scientist in the Baker Lab at the @UWproteindesign.
Leo Zang @LeoTZ03
3K Followers 484 Following Protein Designer | Share Reading Notes (AI+Protein/RNA/DNA) | PhD student @harvardmed @DeboraMarksLab | Hosting @ml4proteins
Ariel Ben-Sasson @Arielbs100
428 Followers 376 Following I design complex protein assemblies, engineer de-novo biologically active structures, and envision the next generation of sustainable and living materials.
Valence Labs @valence_ai
6K Followers 30 Following Decoding biology to radically improve lives. Powered by @recursionpharma
Matthew O’Meara @momeara
795 Followers 3K Following Assistant professor at UMich with a focus on computational pharmacology. (he/him)
Chaitanya K. Joshi @chaitjo
9K Followers 974 Following PhD student @Cambridge_CL. Research Intern @AIatMeta and @PrescientDesign. Interested in Deep Learning for biomolecule design.
Together AI @togethercompute
51K Followers 390 Following AI pioneers train, fine-tune, and run frontier models on our GPU cloud platform.
Shengpu Tang @shengpu_tang
565 Followers 285 Following RL + healthcare | Asst Prof Emory CS | PhD CSE@U-Mich 2024
Sarah Gurev @sarahgurev
1K Followers 2K Following Postdoc with Debora Marks. Previously MIT EECS PhD. Starting FutureHouse Fellowship (in SF for September). Come talk to me about modeling viral/immune proteins!
Chris Lin @chrislin97
69 Followers 65 Following PhD student @uwcse. Previously @ucberkeley and @stanford.
VantAI @vant_ai
3K Followers 10 Following Unlocking a new chapter in medicine by making protein interactions programmable
Nathan C. Frey @nc_frey
4K Followers 1K Following CTO & Co-Founder, Coefficient Bio | Ex-@PrescientDesign • @Genentech | Advisor @atomscale & @guidelabsai | @MIT, @Penn PhD, @BerkeleyLab
Shunzhi Wang @wang_shunzhi
908 Followers 700 Following @BWFund CASI fellow | Postdoc @UWproteindesign | @NUChemistry @CHADNANO alum | De novo protein design for programmable self-assembly
Florian Praetorius @FloPraetorius
692 Followers 207 Following Biomolecular designer; currently postdoc @UWproteindesign; starting my lab @ISTAustria in March 2024 @flopraetorius.bsky.social
Linna An @alchemist_an
777 Followers 468 Following TTAP @RiceUniversity | computational biochemist | Protein designer @UWproteindesign & natural product biochemist @ChemistryUIUC | open to industry
Jason Zhaoxing Zhang @jasonzxzhang
1K Followers 734 Following Molecular tool designer for signaling | Assistant Professor at @UCLA | 🏳️🌈🇺🇸 not on Twitter, on BlueSky: https://t.co/eaiMcFDhE1
Ben Chamberlain @DrBPChamberlain
2K Followers 793 Following Building foundational models of science @EITOxford https://t.co/qukbizP2Yn 🎓 https://t.co/Ln7xZeV3OA
Max Jaderberg @maxjaderberg
15K Followers 1K Following Chief AI Officer @IsomorphicLabs. Prev: Deepmind, Vision Factory (acq. Google), Oxford VGG.
Isomorphic Labs @IsomorphicLabs
29K Followers 75 Following We are reimagining the entire drug discovery process from first principles with an AI-first approach. Learn more: https://t.co/eC7rjmB3EZ
Demis Hassabis @demishassabis
495K Followers 152 Following Nobel Laureate. Co-Founder & CEO @GoogleDeepMind - working on AGI. Solving disease @IsomorphicLabs. Trying to understand the fundamental nature of reality.
Tim Green @tfgg2
3K Followers 2K Following Research Engineer at @GoogleDeepMind, co-led the AlphaFold team, now working on LLMs for science. Previously @democlub and physics.
Benedikt Singer @SingerBenedikt
83 Followers 198 Following PhD Student at EPFL, Switzerland | Working on AI for Protein Design | he/him | Find me on BlueSky: @benediktsinger.bsky.social
Michael Albergo @msalbergo
2K Followers 2K Following Junior fellow at the Society of Fellows at @Harvard and @iaifi_news fellow, incoming Assistant Professor at @Harvard and the @KempnerInst views my own
Hannes Stärk @HannesStaerk
12K Followers 411 Following @MIT PhD student • ML for molecules and biology https://t.co/hEtGZrEHqu
Jason Yim @json_yim
2K Followers 324 Following PhD student @MIT_CSAIL. Generative models, protein design. 🦋 Bluesky handle: https://t.co/MPlEjog02q On X until the exodus is complete.
Una Wen-lii Natterman... @unattermann
864 Followers 864 Following she/her | Co-Founder & Scientist @Pioneer__Labs | Formerly: Postdoc @MITdeptofBE Voigt Lab 🧬🧫 PhD @UWproteindesign 💎🔬
Indrek Kalvet @ikalvet
675 Followers 334 Following 🇪🇪 De Novo enzyme design • HHMI Postdoc at the Institute for Protein Design at University of Washington @UWproteindesign
Andy Hitchcock @HitchcockLab
276 Followers 245 Following Royal Society University Research Fellow at the University of Sheffield
Kiera Sumida @KieraSumida
371 Followers 78 Following Enzyme designer // PhD student @UWproteindesign
Bruno Correia @befcorreia
3K Followers 733 Following Professor in Bioengineering @epfl 🇨🇭| protein designer
Helen Eisenach O'Brie... @HelenEisenach
874 Followers 327 Following Baker & King labs @UWproteindesign | alum @Harvard | novel protein nanomaterials and deep learning
Thomas Schlichthaerle @schlichthaerle
490 Followers 382 Following PostDoc working on Protein Design problems in the Baker Lab, previously working with DNA-PAINT & DNA Nanotechnology
Boston Protein Design... @ProteinBoston
5K Followers 77 Following a community of computational protein engineers and modelers from both academia and industry an @openmsf project organized by @bahl_lab @nickpolizzi_ @sokrypton
Green Ahn @Green_Ahn
637 Followers 211 Following @JCChildsFund Postdoctoral Fellow in David Baker’s Lab at IPD @UWproteindesign. PhD w/ @CarolynBertozzi @Stanford
Oxford Protein Inform... @OPIGlets
2K Followers 240 Following Research group led by Charlotte Deane, based in the Department of Statistics at the University of Oxford.Trends for United States
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