SARS-CoV-2 Science Updates @Sarscov2science
SARS-CoV-2 Virology World Joined August 2019-
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Today we played around with the homology model of M protein from #coronavirus generated by @DeepMind using #AlphaFold Check out the other proteins they modeled: deepmind.com/research/open-… #sciart #covid19 #SARSCoV2
Pretty cool video that @YaleMed made of our SARS-CoV-2 genomic epidemiology research. They took several images from @nextstrain - so gotta give credit to those hard working folks! youtube.com/watch?v=UTzUtW…
Interesting that anti-SARS-CoV mAb m396, though ineffective against SARS-CoV-2, binds KGD in SARS-CoV (RGD in SARS-CoV-2) as well as ACE2 binding residues (Fig. 4). Could it be engineered to recognise SARS-CoV-2 & block ACE2 & (potential) integrin receptors? #COVID19
Interesting that anti-SARS-CoV mAb m396, though ineffective against SARS-CoV-2, binds KGD in SARS-CoV (RGD in SARS-CoV-2) as well as ACE2 binding residues (Fig. 4). Could it be engineered to recognise SARS-CoV-2 & block ACE2 & (potential) integrin receptors? #COVID19
A fantastic infographic here from @FalconieriV on the SARS-CoV-2 spike protein #COVID19
A fantastic infographic here from @FalconieriV on the SARS-CoV-2 spike protein #COVID19
We're launching a new UniProt portal covid-19.uniprot.org for the latest pre-release SARS-CoV-2 #Coronavirus and receptor proteins, updated independent of the general UniProt 8-weekly release cycle. Click the link or find the red button on the uniprot.org homepage.
NEW @JAMA_current @BradSpellberg @SBtotheDub Community Prevalence of SARS-CoV-2 Among Patients With Influenzalike Illnesses Presenting to a Los Angeles Medical Center in March 2020. #COVID19 jamanetwork.com/journals/jama/…
SARS-CoV-2 is a betacoronavirus, and part of the coronavidae family. These viruses have the biggest genomes of any known RNA viruses (≈30 kb). Coronaviruses have very low mutation rates for RNA viruses (≈1e-6 mutations/nt/cycle) because of a proofreading mechanism.
"Of note, these viruses do not appear to cause disease in bats"-- - Nipah virus - Hendra virus - SARS-CoV - SARS-CoV-2 - MERS-CoV - Ebola - Marburg "ability of bats to harbor these viruses with no observed clinical consequence" frontiersin.org/articles/10.33…
You are still far, far, far more likely to get SARS-CoV-2 from a human than a cat. sciencenews.org/article/cats-a…
Pangolins can harbor coronaviruses, but it doesn’t look like SARS-CoV-2 came from them. sciencenews.org/article/covid-…
#CoronavirusOutbreak | SARS-CoV-2 doesn’t survive on print or tissue paper for more than 3 hours, a new study by the School of Public Health at the University of Hong Kong has found. (by @jayashreenandi) hindustantimes.com/india-news/no-…
1/3 The @_aacc community discussion group for SARS-CoV-2 testing is set up. Open to non-members, too. Please share your knowledge and help everyone fight this pandemic effectively and resourcefully! artery.aacc.org/home
Today, the U.S. extended a program, defunded last year, to stop pandemics by studying wildlife viruses. For today's very first issue of Lancet Microbe, I've written about USAID PREDICT, why it was important, and why it wasn't enough to stop COVID-19: thelancet.com/journals/lanmi…
FDA warns about possible SARS-CoV-2, COVID-19 transmission with FMT healio.com/gastroenterolo… @HealioGastro @DrJessicaA
Live Q&A: Health behaviors are contagious through social networks. @NAChristakis from @YaleSoc discusses #COVID19 contagion, social distancing, and the pandemic. #Coronavirus #SARSCoV2 #JAMALive pscp.tv/w/cVJJejFXZ0tn…
Cayman now carries detection assays for the 2019 novel Coronavirus (SARS-CoV-2). These include nucleic acid detection and indirect ELISA detection tools for evaluation of anti-SARS-CoV-2 Spike S1-RBD IgG or IgM in samples. caymanchem.com/search?q=gensc…
Practice Recommendations on Neuraxial Anesthesia and Peripheral Nerve Blocks during the COVID-19 Pandemic joint statement with @ESRA_Society just published. @KalagaraHari @Ropivacaine @rakesh6282 @claralexlobo asra.com/page/2905/prac…
New! Practice recommendations on RA under the reign of #SARS_COV_2... #EverythingWillBeAlright @ESRA_Society #COVID19 #RegionalAnesthesia
New! Practice recommendations on RA under the reign of #SARS_COV_2... #EverythingWillBeAlright @ESRA_Society #COVID19 #RegionalAnesthesia
Epitope-based chimeric peptide vaccine design against S, M and E proteins of SARS-CoV-2 etiologic agent of global pandemic COVID-19: an in silico approach biorxiv.org/cgi/content/sh… #bioRxiv
Our preprint profiling host molecules related to SARS-CoV-2 infection in human lung tissue and epithelium - at gene and protein level - is now out. @DrLindskog @ACDoxey @IPFdoc @sci_questions @Millerlab_atMac @MossmanLab @PollutionLab @McMasterU biorxiv.org/content/10.110…
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