Saumya Das @SaumyaDas_Lab

Scientist, physician and outdoor enthusiast. Tweets are my own views. Joined October 2020

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Saumya Das @SaumyaDas_Lab

a year ago

Our work on the discovery of cardiac specific EVs and analysis of their cargo RNAs as representative of cardiomyocyte disease pathways was well received at the GRC-EV conference. #GRCconference, @mghcvrc

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Saumya Das @SaumyaDas_Lab

a year ago

So cool to have amazing summer students and interns from across the world and the US work with us to get a good sense of research in the clinical/translational arena. Meaningful contributions to several projects. @mghcvrc

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Saumya Das @SaumyaDas_Lab

a year ago

RNA therapeutics and gene/RNA editing will allow for truly personalized approaches to therapy. Important for patient voices and what matters for outcomes to be heard by regulators and scientists alike.

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Saumya Das @SaumyaDas_Lab

a year ago

Delighted to attend and present at #RNATx2024 @RTI_UMassChan our work on tRNA derived small RNAs and their role in kidney disease, led by @GuopingLi2 with many collaborators. Some robust discussion on defining mechanisms and designing therapeutics.

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Saumya Das @SaumyaDas_Lab

a year ago

Lab members and families out for summer celebration of transitions, successes (papers, talks). Lots to celebrate.

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Saumya Das @SaumyaDas_Lab

a year ago

Lab transitions/graduations: sad and happy at the same time. Guoping Li: congratulations on Assistant Prof position at MGB/HMS; Michail Spanos: Physician-scientist residency at Jacoby/Sinai; Olivia Whitaker/Lingfei Sun: MD/and or MPH! @mghcvrc

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Saumya Das @SaumyaDas_Lab

a year ago

A lot of fun to visit Jose Huizar, Fadi Salloum @VCUHealth to talk about translation of basic discovery to human studies led by @ThryvTrx and our work on cardiac specific EVs led by @Michail_Spanos_ @PriyankaGokuln and @GuopingLi2

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Saumya Das @SaumyaDas_Lab

2 years ago

The study was possible with funding from @AmericanHeart and @nih_nhlbi. Work done collaboratively with @mghcvrc @TGen and @VUMChealth. First study to show mapping of EV transcripts to single nuclear RNAseq atlas. ahajournals.org/eprint/KAIQX6T…

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Saumya Das @SaumyaDas_Lab

2 years ago

How can one non-invasively sample the transcriptome of organs like the heart. Our study now published in @CircAHA shows the mapping of differentially expressed transcripts in HFpEF and HFrEF mapping to different cardiac cell-types. ahajournals.org/eprint/KAIQX6T…

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Saumya Das @SaumyaDas_Lab

2 years ago

4 years of hard work led by Dr. Guoping Li to develop tools to manipulate tDR expression and careful studies to understand the mechanistic link between tDR and cellular response to injury. Now poised as possible new therapeutics! @GuopingLi2 @mghcvrc

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Saumya Das @SaumyaDas_Lab

2 years ago

tRNA-derived small RNAs have burst in the scene as novel mediators of cellular stress responses. Was a pleasure to present some of our work on Asp-GTC-3'-tDR playing a role in RNA autophagy in kidney cells at the RNA therapeutics conference @cityofhope

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Saumya Das @SaumyaDas_Lab

2 years ago

Our new study in collaboration with Abbott showcases the potential of adding plasma miRNA biomarkers to traditional protein biomarkers. Effect sizes still small, but point to interesting pathways. doi.org/10.1002/ehf2.1…

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Saumya Das @SaumyaDas_Lab

2 years ago

Congratulations to Marta Garcia Contreras from our group for being selected as a Rising Star at the NIA conference on biomarkers of stress and resilience. Microglial EVs may reflect disease state in neuroinflammation! @mghcvrc @NIHAging

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Saumya Das @SaumyaDas_Lab

2 years ago

Pleasure to present our work. Hopefully tissue specific EVs will improve the diagnostic yield of EV biomarkers; specificity of antibodies remains a challenge down the road.

Michail Spanos @Michail_Spanos_

2 years ago

Pleasure to present our work. Hopefully tissue specific EVs will improve the diagnostic yield of EV biomarkers; specificity of antibodies remains a challenge down the road.