Venture capital engineered to ignite your growth. Founded as a tech company. Built like the startups we fund. https://t.co/yjltHaTl8Wsignalfire.com San FranciscoJoined May 2007
Forget Microsoft Office. If it were invented today, it would look like @useMotion that just raised $60M at a $550M valuation.
- 100K+ paying customers
- ARR 3x YoY
- $10M new ARR from AI Employees in 4 months
Businesses of any size now have AI teammates that not only track work…
On Christmas Eve 2019, Michael Seibel, then CEO of YC, called me: “You might not be cut out to be a founder.” He was right. We had pivoted 20 times. I thought I could always return to my 7-figure quant job. That night, I realized: you commit or you quit. Fast forward: Motion…
@IlyaKirnos and I recently chatted on a panel with @gracegongGG on AI.
I mentioned what I think are the next 3 waves of AI. It’s a bit contrarian because I don’t think it’s a massive AGI service… but instead it’s about “inference to actuators”
Wave 1: Intelligence at the…
Biopharma’s old playbook was built on a $140B outsourced services market, but the entire value chain is evolving with #AI agents. 💊
Half of pharma’s R&D spend flows to CROs and CDMOs, yet the system remains slow, error-prone, and fragile. With a $236B patent cliff approaching…
psst… we’re throwing another epic after-party for TechCrunch Disrupt, taking over a whole vintage hotel.
Reply for early RSVP access. See you poolside.
Incumbents & Insurgents - New podcast alert for our Health & PharmaTech AI community🚀
“US healthcare has the largest surface area exposure to disruption and reshaping from #GenAI.”
-Eric Larsen, President of TowerBrook Healthcare Institute & Venture Partner of @SignalFire…
Super fascinating tech talent trends from @SignalFire 's new report: Diplomas not required, fewer managers per engineer, and Anthropic wins as Tesla loses.
Here are the highlights:
-No college degree needed: 15% of engineers at Microsoft & Adobe and 13% at Apple & Netflix…
AI isn’t a feature. It’s the new OS for work.
@Grammarly's acquisition of @Superhuman is a power move, and we’re proud to have been early investors in this vision.
From 500K+ app integrations to agentic collaboration, Grammarly is building one of the most-used AI platforms in…
AI isn’t a feature. It’s the new OS for work.
@Grammarly's acquisition of @Superhuman is a power move, and we’re proud to have been early investors in this vision.
From 500K+ app integrations to agentic collaboration, Grammarly is building one of the most-used AI platforms in…
This is the future we've been building toward since day one: AI that works where people work, not just where companies want them to work.
Thrilled to announce @Grammarly intends to acquire @Superhuman to bring our agentic vision to life. Email is the perfect staging ground for…
Mandolin lands $40M to accelerate access to life-saving specialty drugs with AI agent platform
Infusion and specialty therapies represent:
💊 ~75% of the FDA approval pipeline
💵 $250B in drug spending and projected to reach $1.5T by the mid-2030s
But these specialty…
🚨 IT’S OFFICIAL
🗽 Borough Blitz: NY vs The World
June 27–29 | NYC + Global
Presented by @SignalFire + @Azure
🔥 The first AI hackathon where NYC takes on the world for the VIBE CODING crown.
🔗 lu.ma/nla77cu6#VibeCoding#AIHackathon#NYTech
Who is game?
It shouldn’t take 30+ days to access life-saving cancer or Alzheimer’s medication. And yet that's the reality for millions of patients seeking care. Mandolin has raised $40M to fix that with AI agents that automate the paperwork clogging infusion centers and specialty…
Superdial raises a $15M Series A led by @SignalFire and we hosted @sam_schwager (Co-founder & CEO) on the show.
"Our core is handling phone calls between RCM (Revenue Cycle Management) companies and the billing teams within providers, or outbound calls to insurers."
"There are…
116K Followers 3K Following1st African to buy Bitcoin Since 2011 @ $35 I GUIDE HIGH NETWORTH INDIVIDUALS INVEST IN BITCOIN.!Building Africa first Bitcoin Treasury Company @esvcapital
114 Followers 1K Following[wash-CHILL-ow]he/him
i make apps📱https://t.co/y6wUGHr4Jj
i consult startups 🚀 https://t.co/pCHaWYM3Q3
i help Autistic adults 🧠 @stimmieapp
3K Followers 2K Followinglaunching something new soon … | prev. CTO @thespartanlabs | building at the intersection of Ai and Web3 | Always stay gracious, the best revenge is yo’ papers
2 Followers 37 FollowingAfiyavest is a healthtech and fintech platform that enables underserved communities to access healthcare through micropayments, wallets, and donor support.
344 Followers 2K FollowingActively hiring Engineering, Product, and Design Talent for early-stage B2B.
Connecting the best talent with @amplifypartners VC.
1K Followers 4K FollowingCloud and AI at Microsoft, reformed startup addict, whiteboard enthusiast, and geriatric millennial. @goingvc Cohort 17. All words are absolutely my own.
430 Followers 734 Followingbuilding AI for 100M people who need compelling data visuals every week | ceo @givance_ai | 2x exits | 500x failures | 1x asteroid | prev @StartX/@AlchemistAcc
235 Followers 912 Following✡️✝️⭐VC & PE Leader | Own a Billionaires Private Society (Dubai) under Dynasts & Legacy Secret Society (Israel) | Founder & CEO to a Global Private Equity Firm
2K Followers 4K FollowingManaging Director at @Google. Advisory Board at @KingsTrust. Board and Trustee at @Media_Trust. Tech, AI, media, digital, skills and social mobility.
603K Followers 5K FollowingPresident & CEO @ycombinator —Founder @Initialized—designer/engineer who helps founders—San Francisco Dem accelerating the boom loop—e/acc—technology brother
126K Followers 3K FollowingCo-founder @hustlefundvc. Building a hippocorn company -- market size unknown. Democratizing wealth via entrepreneurship. SF Bay Area native.
178K Followers 116 FollowingThe latest scoops and features from @WSJ’s Wall Street team covering banking, private equity, M&A, IPOs, activism, hedge funds, fintech and more.
1.8M Followers 378 FollowingThe Wall Street Journal's Business editors share the latest breaking news and their insights on what matters most in business and finance.
2K Followers 1K FollowingFounder @Nucleus_Talent | Exec search for VC + startups | SF lover, golfer(ish), tech junkie | Big on vibes, vision & people who give a sh*t.
205K Followers 5K FollowingVC at @MenloVentures. Formerly founding team @glean, @Google Search. @Cornell CS. Tweets about tech, immigration, India, fitness and search.
243K Followers 2K FollowingSign up for my new newsletter! (Link below) Also: Co-author of Abundance, host of Plain English, and contributing writer at The Atlantic.
9.8M Followers 101 FollowingThe first word in business news. Singapore newsletter: https://t.co/RtyaUOdLdF Newsletters: https://t.co/nWaCxHSKuU Podcasts: https://t.co/096e9xMbPz
2.0M Followers 226 FollowingBreaking news and analysis on global markets
Live updates: https://t.co/5fCN0iMdOA
Sign up for the new Markets Daily newsletter: https://t.co/jPvsdu1EIP
19K Followers 2K FollowingObsessed with technical founders building products for themselves. Talent is universal, while opportunity is not. Early stage VC.
58K Followers 977 FollowingSeed. Early. Growth. We invest across consumer and enterprise and have partnered with thousands of inspiring entrepreneurs over the past two decades.
193K Followers 9K FollowingHome of everything AI — Here to help you use Al to boost your productivity — Daily insights on AI tools & tips || DM for collaborations [email protected]
13K Followers 2K FollowingThe future is agentic! COO @crewAIInc. 15+ years building AI cos. Former exec at 3 AI cos. (CEO @ BackboneAI, COO @Kustomer, CEO @Datasift.). 🗽🏃♂️. 🇺🇦🇮🇱
3K Followers 2K FollowingFollow me for startups, AI, deeptech, biotech, cleantech. CEO of Trellis Air. Former CEO of @Eink. Venture partner @pillar_vc.
7K Followers 2K FollowingEarly-stage, Boston-based venture capital firm backing bold entrepreneurs with an aligned community designed to fit each startup's unique needs.
2K Followers 669 FollowingGrowth and AI Product Guy | Always building something new. | Previously co-founder of Lasso AI (Acquired) | Writing @ https://t.co/3krJHoFMbk | 🇮🇪 in 🇺🇸
45K Followers 2K FollowingA venture capital firm that strives to have a positive impact on everything we do. When we invest, we're invested. When we’re in, we’re all in! #teamwork
26K Followers 453 FollowingA seed-stage fund that helps you build the next billion-dollar company. Since 2013, we've partnered with over 100 companies - 10% have become unicorns.
No recent Favorites. New Favorites will appear here.