Tweets on all aspects of Springer’s Pathology publishing program. Check out this space for free to read articles, upcoming conferences and much more..springer.com/pathology New York Heidelberg LondonJoined January 2014
The identification of the MEF2A::NCOA2 fusion in this gastrointestinal tumor may suggest a new entity related to previously reported myxoid epithelioid smooth muscle tumors in the vulvovaginal region, warranting further investigation.
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Genetic analysis of a patient with colorectal and oesophageal cancers identified a variant in the MSH2 gene, initially classified as uncertain but later linked to Lynch syndrome, emphasizing the need for thorough genetic evaluation in cancer cases.
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Virchows Archiv reports on a study of appendiceal goblet cell carcinoma (GCA) revealing that 17% of cases had coincident sessile serrated lesions or low-grade mucinous neoplasms. The study utilized paired next-generation sequencing for analysis.
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The Journal of Hematopathology reports a case of mixed-phenotype acute leukemia (MPAL) with BCR::ABL1 fusion, revealing distinct T-lymphoblastic and B-lymphoblastic/myeloblastic populations in different anatomical sites.
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The case presented involved a 64-year-old carpenter with nasal congestion and epistaxis. Imaging revealed a significant lesion, leading to a diagnosis of high-grade sinonasal adenocarcinoma associated with HR-HPV, underscoring clinical implications.
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A case study in Head and Neck Pathology details a 12-year-old male with mandibular epithelioid osteoblastoma, showing cortical expansion and tooth displacement. Imaging revealed a 4.7 cm mass with calcifications and periosteal reaction.
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A @HeadNeckPathol letter offers suggestions for enhancing the study including expanding sample sizes and utilizing larger spatial transcriptomics datasets. This could uncover additional immune-modulatory roles that weren't detected in the current analysis.
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A study in Comparative Clinical Pathology investigates the role of phosphotransfer enzymes in energy dysfunction during cryptococcosis. Findings show significant changes in enzyme activities in brain and lung tissues post-infection.
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Research shows that feeding Large White Boars with Aspilia africana leaf meal enhances serum protein levels and reduces cholesterol. Optimal results were observed at 5% inclusion, suggesting benefits for animal health and reproduction.
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Comparative analysis shows over 200 differentially expressed genes between PDTC and ATC, indicating a consistent downregulation in PDTC. These findings may inform future therapeutic strategies for thyroid cancer.
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Virchows Archiv reviews 43 cases of renal solitary fibrous tumors (SFT), highlighting their clinical and morphological features. The study applies a four-variable risk stratification based on age, size, mitotic activity, and necrosis.
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Virchows Archiv highlights the importance of histopathology in diagnosing invasive fungal infections, emphasizing the need for specialized infectious disease pathologists due to the complexity of fungal identification.
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Research involving 88,713 patients highlights the impact of different HER2 antibodies on diagnosing HER2-low breast cancer. Variability in results across laboratories could influence treatment decisions for trastuzumab-deruxtecan.
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The findings in Virchows Archiv reveal distinct morphological features in PML::JAK1 fusion sarcomas, including lobulated growth patterns and branching blood vessels. This adds to the complexity of diagnosing these tumors.
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Among 26 cases of LG DDLPS, 7.7% developed lung metastasis, indicating a more aggressive nature than previously thought. The findings published in Virchows Archiv stress the importance of accurate diagnosis and monitoring in liposarcoma cases.
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Virchows Archiv reports on two cases of HHV8-related multicentric Castleman disease diagnosed through splenectomy. Patients presented with splenomegaly and lymphadenopathy, revealing mixed histological patterns in tissue analysis.
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The Journal of Hematopathology documents a case of in situ follicular neoplasia (ISFN) found within a sebaceous lymphadenoma, a rare occurrence. This highlights the need for thorough evaluation of lymphoid-rich salivary gland tumors.
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The Journal of Hematopathology reports on a study validating the MDS-International Working Group's classification of myelodysplastic syndromes, applying it to 484 cases and confirming key associations with prognosis and clinicopathological features.
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The identification of the BMPR1B::AFF2 fusion in sinonasal tumors suggests that molecular subclassification can improve prognostic accuracy and treatment options, highlighting the evolving landscape of head and neck pathology diagnostics.
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RNA sequencing confirmed a novel FRK fusion in the oncocytic intraductal carcinoma case, suggesting its role in aberrant signaling pathways linked to cancer. This adds to the understanding of genetic diversity in this tumor type.
@HeadNeckPatholbit.ly/46cOlGB
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21K Followers 10K FollowingPresident of the Brazilian Society of Pathology
Surgical Pathologist -
Lapac Lab -
🔬Interested in GIPath
Teresina - Brazil 🇧🇷
5K Followers 127 FollowingThe leading force in European Pathology
VIAR is the ESP Official Journal
The European Congress of Pathology is organised by ESP #ESPCongress
#EveryDayPathology
13K Followers 2K FollowingPathologist (Professor), Meram Faculty of Medicine, Konya/Turkey; I lv #hemepath, #dermpath 💗Married and have 4 children, RT/Tw are not medical advice
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