🧵 A new study published in @LancetMicrobe unveils significant advancements in understanding post-COVID-19 condition, also known as "long COVID." Let's dive into the key findings of this research. #LongCOVID #COVID19 1/8
🧵 A new study published in @LancetMicrobe unveils significant advancements in understanding post-COVID-19 condition, also known as "long COVID." Let's dive into the key findings of this research. #LongCOVID #COVID19 1/8
The study employed blood transcriptomics to analyze samples from 48 individuals with long COVID compared to 12 controls, aiming to identify non-invasive biomarkers for diagnosis and clinical management. 🧬🔬 2/8
Continuous presence of SARS-CoV-2 RNA, particularly antisense ORF1ab RNA, suggests the virus may remain active long after initial infection. This could explain some of the persistent symptoms of long COVID. #virology 4/8
Researchers also identified potential biomarkers. RNA levels of FYN and antisense SARS-CoV-2 were found to be reliable predictors of long COVID, offering a diagnostic method with high accuracy. #biomarkers 5/8
Clinical significance: Patient-reported symptom scores, such as anxiety and depression, were significantly associated with higher viral loads, underscoring the link between viral burden and mental health. #mentalhealth 6/8