Marco Trujillo @TrujilloLab
Fascinated by ubiquitination. Works at the RWTH Aachen University. Tweets are my own. @trujillolab.bsky.social trujillolab.com Aachen, NRW, Germany Joined August 2011-
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Marco Trujillo retweeted
Thrilled to share that our manuscript on the differential roles of tomato ubiquitin E1 enzymes in development and host immunity is now published in Molecular Plant Pathology! 🎉 Check it out here: bsppjournals.onlinelibrary.wiley.com/doi/epdf/10.11… Huge thanks to Bangjun, Chaofeng, and Xuanyang for their…
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Marco Trujillo retweeted
Life’s “operating system” is a universal genetic code. For billions of years it seemed frozen. In ChemCatChem we explain why it looks this way - and how we might carefully expand it. DOI: doi.org/10.1002/cctc.2… #GeneticCode #LifeEngineering #SyntheticBiology #Xenobiology
Marco Trujillo retweeted
Excited to showcase published version of our covalent destabilizing MYC degrader in @angew_chem that stereoselectively targets an IDR C203 in MYC! Congrats to Hannah Rosen and Kelvin Li & thanks to #TomMaimone, @NovartisScience & @TheMarkFdn! onlinelibrary.wiley.com/doi/10.1002/an…
Marco Trujillo retweeted
I’m hiring a postdoc biochemist for my team at @TelAvivUni (ISF_NCSF-funded) 🔬 Focus: protein purification, PPI, ubiquitin biology & targeted protein breakdown in plant drought response 🌱☀️ 📩 Send a cover letter & CV to [email protected]
Marco Trujillo retweeted
De novo design of light-responsive protein–protein interactions enables reversible formation of protein assemblies ift.tt/rc5lnRI
Marco Trujillo retweeted
Insecticides made of RNA could offer a safer and more targeted weapon against crop pests. Learn more: scim.ag/41caemw #ScienceMagArchives
Marco Trujillo retweeted
A new #ScienceReview looks at a different approach to drug discovery that may enable drugging of unconventional targets through stabilization of macromolecular complexes with molecules known as “LOCKTACs.” Learn more: scim.ag/4lAiKmF
Marco Trujillo retweeted
Photoexcited CRY1 physically interacts with ATG8 to regulate selective autophagy of HY5 and photomorphogenesis in Arabidopsis (Lu Jiang , Shilong Zhang , et al) doi.org/10.1093/plcell… @ASPB #PlantSci
Marco Trujillo retweeted
The Green Revolution saved 1-2 billion lives globally. Activists say it was a failure. They’re lying! @stuartsmyth66 geneticliteracyproject.org/2025/08/25/vie…
Marco Trujillo retweeted
Back from holidays. During this time, we published two papers about engineering FLS2-flg22 perception, to expand the recognition spectrum, and one News & Views highlighting them: rdcu.be/eBbgd rdcu.be/eBbgk rdcu.be/eBbgm
Marco Trujillo retweeted
PepMLM is out in @NatureBiotech! 🎭Want a short binder for any target? Just input its sequence + desired binder length → PepMLM unmasks it. Simple? No way? The results speak for themselves. 👇 📜: nature.com/articles/s4158… 💻: github.com/programmablebi… 🤗: huggingface.co/ChatterjeeLab/……
Marco Trujillo retweeted
Natural plant populations maintain diverse resistance genes, but crops often lack this diversity, making them vulnerable to rapidly evolving pathogens. @XiaoxiaoZhangA et al. used DNA shuffling on barley Mla7 and Mla13 genes to create MLA variants, some gaining the ability to…
Marco Trujillo retweeted
A review coauthored with Dr. Shuai Huang of Ohio State University on the role biomolecular condensates in plant immune regulation. This emerging field is fascinating, yet still awaits major technological advances to move beyond current limitations. authors.elsevier.com/sd/article/S19…
Marco Trujillo retweeted
🆕 JUST OUT: #Extracellularvesicles: cargo loading, degradation and secretory pathways, and their intersection with #autophagy Prof. Kasper M.A. Rouschop（Maastricht University Medical Center+） 💥 Read now: oaepublish.com/articles/evcna… #EVs #Exosomes @Takahide_Matsui,@sanjeevtmc
Marco Trujillo retweeted
💚My New Cover for @thewoolab @Harvard 💙 This art illustrates the discovery that #cereblon, a key protein in the cell’s waste disposal system, recognizes small chemical tags called #cyclic_imides (shown here in green at the tips of proteins). These naturally form at the end of…
Marco Trujillo retweeted
Finally published. A big thank you to all contributors: Barley resistance and susceptibility to fungal cell entry involve the interplay of ROP signaling with phosphatidylinositol‐monophosphates - Weiß - 2025 - The Plant Journal - Wiley Online Library onlinelibrary.wiley.com/doi/10.1111/tp…
Marco Trujillo retweeted
Undruggable ‘disordered’ proteins become druggable with new AI techniques from David Baker. @ScienceMagazine science.org/doi/10.1126/sc…
Marco Trujillo retweeted
RNF114 is an E3 ligase that can recognize ADP-ribose and ubiquitin with separate domains. A proteomics approach is developed using these domains to map ADP-ribosyl-ubiquitylation sites nature.com/articles/s4158…
Marco Trujillo retweeted
Are mini proteins the new antibodies? Mini proteins are highly stable, easy to manufacture, and very quick to design thanks to recent AI methods. Unlike mAbs, there is a large body of structural data to train machine learning models on to generate de novo mini protein binders.…
Marco Trujillo retweeted
SIZ1 SUMOylates and stabilizes WRI1 to safeguard seed filling and fatty acid biosynthesis under high-temperature stress (Ruihua Huang , Mengrui Wen , Bojin Feng , et al) doi.org/10.1093/plcell… @ASPB #PlantSci
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