Nature Chemical Biology @nchembio
A scientific journal devoted to publishing the most compelling research, opinion and analysis at the intersection of chemistry and biology. nature.com/nchembio New York, USA Joined March 2009-
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A new paper from the Roll-Mecak team revealed the structure of a tubulin code writer showing how it reads microtubule geometry and modification state of neighboring tubulins, enabling a spatial positive feedback loop for microtubule modification rdcu.be/dFLgf
A News & Views by Daniel Richter and Anna Lisa Vagstad highlights work @NatureComms on the ID and complete biosynthetic reconstitution of dehydrazoles, a new class of hypermodified RiPPs. Read it here rdcu.be/dFLfx and the original paper rdcu.be/dFLfv
Ting Liu and colleagues report UFL1, a UFM1-specific E3 ligase, as a regulator of replication fork degradation and the response to PARP inhibitors in BRCA1/2-deficient cells. rdcu.be/dFLdr
Cal-ID, a calcium-dependent protein proximity labeling tool, is finally published @nchembio! We (@nickingolia) present a simple, scalable, in vivo compatible, and versatile platform that connects calcium signals to biochemical labeling of proteins. rdcu.be/dFDrb
A Meeting Report highlights the latest research that convened at the 2023 Bringing Chemistry to Medicine symposium at St. Jude Children's Research Hospital focused on targeting dysfunctional gene regulation and other 'undruggable' processes rdcu.be/dE25H
A new paper reports the engineering of cytosine base editors with a narrow editing window and minimal off-target effects. Free to read link at rdcu.be/dE237
A News & Views by Martin Zacharias and Sebastian Springer highlights recent work @J_A_C_S on the design of peptide vaccines. Free to read link at rdcu.be/dE22d and link to the original article pubs.acs.org/doi/10.1021/ja…
Super psyched to see this published at last! We demonstrate a novel approach to slowing alpha-synuclein aggregation in #Parkinsons. A massive thank you to the @VendruscoloLab, @KnowlesLabCamb, Caughey, Ghetti and Sormanni labs. cam.ac.uk/research/news/… nature.com/articles/s4158…
A new paper from Zhimin Lu revealed that TERT was dephosphorylated by the protein phosphatase activity of the gluconeogenic enzyme FBP1, leading to inhibition of TERT nuclear translocation and telomere function. Free to read link at rdcu.be/dCMu9
A new paper developed a massively parallel screening platform for studying sensitivity of human signal peptides to Sec61 inhibitors. Free to read link at rdcu.be/dCMsx
So excited to see our work on "Profiling the proximal proteome of the activated μ-opioid receptor" using APEX-based proximity labeling and quantitative mass spec published today. It is the result of an amazing team effort! nature.com/articles/s4158… #TeamMassSpec #Proteomics #GPCR
I am excited to share that my first first-author publication from my graduate work with @DrewAdamsLab is out in @nchembio! Here, we used many small molecule probes to spotlight an underappreciated role of XPO1 as a chromatin factor: nature.com/articles/s4158… (1/9)
I'm thrilled to share, our work is online now @nchembio. Huge thanks to Ruma Banerjee, @YatrikShahLab @lyssiotis and all authors @rashi_singhal7 @SumeetASolanki @SAlibeckoff @Hannah_N_Bell and others.rdcu.be/dBSCb
A new paper reports the de novo design of amyloidogenic peptide traps. Read it here rdcu.be/dB3Ie
Excited to share E3-substrate tagging by ubiquitin biotinylation (E-STUB) @nchembio! E-STUB enables CUL-RING ligase substrate identification and may transform the way we study glues and PROTACs by directly studying substrate ubiquitylation. 1/ rdcu.be/dBZKx
A new paper reports the design of synthetic transmembrane proteins to regulate a target cytokine receptor. Free to read link at rdcu.be/dBTCy
A new paper from @Wiegand_lab @sapunp1 @MichaelsLabETH reveals a crust-like β-sheet structure is formed on the surface of FUS droplets during aging. Free to read link at rdcu.be/dBTAF
How benchmarking challenges and data in the public domain will guide development in AI-based methods and breakthroughs in #drugdesign on a scale analogous to that seen for protein fold prediction? @mattschap @LabScribbles @CherylArrowsmi1 @HalabelianLab nature.com/articles/s4158…
💊 Accessing natural vaccine adjuvants. 💉 nature.com/articles/s4158… 👍 Thanks @v_courdavault for this collaboration to write a spotlight @nchembio on the awesome @AnneOsbourn1 lab report (nature.com/articles/s4158…) 👏 @BBVEA2106_Tours @UA_Recherche @FacSante_Angers @chu_angers
Carolyn Bertozzi @CarolynBertozzi
77K Followers 3K Following Prof. @StanfordUChem; Baker Family Director, @Stanford_ChEMH; @HHMINews Investigator; EIC of @ACSCentSci; She/Her 🏳️🌈
Frances Arnold @francesarnold
65K Followers 774 Following Innovation by evolution, Linus Pauling Professor at Caltech, Nobel Prize in Chemistry (I am an engineer of the biological world)
Nature Biotechnology @NatureBiotech
302K Followers 2K Following Publishing the very best of biotech science and business. Part of @SpringerNature and @NaturePortfolio. On Facebook (natbiotechnol) & IG (nature.biotechnology)
Ingo Hartung @HartungIngo
14K Followers 780 Following MedChem @Merckgroup; drug discovery nerd in oncology, immunology & targeted protein degradation, soccer, politics or tapas can get into the way; my own views
Dan Nomura @DanNomura
17K Followers 9K Following Professor of Chemical Biology and Molecular Therapeutics at UC Berkeley; Departments of Chemistry and Molecular and Cell Biology
Craig Crews @CraigMCrews
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Jay Bradner, M.D. @jaybradner
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bryan dickinson @chembioBryan
6K Followers 1K Following chemical/synthetic biologist but generally motivated by making molecules that do stuff, dad, @uchicago professor of chemistry
Jeremy Baskin @basktastic
5K Followers 1K Following Click chemist, cell biologist, #chembio & #lipidtime enthusiast, occasional classical pianist (he/him). Also @[email protected]
ChemBioChem @ChemBioChem
11K Followers 2K Following Rapid. Fair. Unbiased. Core journal for breakthroughs across all areas at the interface of chemistry & biology. #ChemBioTalents. Published by @ChemEurope.
Marnix Medema @marnixmedema
6K Followers 2K Following Professor of Bioinformatics at Wageningen University, Visiting professor at Leiden University. Natural product discovery, microbiomes, method development.
Olalla Vázquez @OlallaLab
7K Followers 4K Following Professor of Chemical Biology at @Uni_MR. Optochemical tools for controlling biological processes at molecular level. Epigenetic chemical probes. Be Light!✨✨
Dirk H. Trauner @DirkTrauner
16K Followers 12K Following Penn Integrates Knowledge Professor, Natural Product Aficionado, Photopharmacologist, Fox Terrierist, and Unfulfilled Architect. #firstgen
Laura Kiessling @ChemicalBiology
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Georg Winter @georg_e_winter
4K Followers 993 Following Chemical Biologist with passion for Cancer Research, Targeted Protein Degradation & Transcription.Scientific Founder of Proxygen & Solgate. Pats Fan. Dad.
Nature Reviews Drug D.. @NatRevDrugDisc
38K Followers 479 Following Editorial team of Nature Reviews Drug Discovery.
Ben Schumann @DrGlycoBen
4K Followers 1K Following Group Leader @TheCrick and @Impchemistry. We are making next-generation chemical tools to understand glycans in biology. @[email protected]
Michael C. Jewett @MichaelCJewett
7K Followers 483 Following Professor of Bioengineering, Stanford University
Stephan Hacker @StephanHacker2
5K Followers 2K Following Assistant Professor @LeidenScienceEN. Covalent inhibitors and chemoproteomics for antibiotics. Views my own. Also on https://t.co/OnUZrMJH69 and https://t.co/5xQ0wrIide. he/him/his.
James Olzmann @OlzmannLab
10K Followers 7K Following Associate Professor @UCBerkeley & Investigator @czbiohub. Lipid droplets, ferroptosis, ubiquitin, chembio, molecular therapeutics. Diversity, equity, inclusion.
Jeff Chen @Jeff_Y_Chen
45 Followers 146 Following PhD student in Chemistry at the University of Illinois Urbana-Champaign
GPR @gnropimienta
0 Followers 46 Following
Yodysseus @YodysseusX
0 Followers 117 Following
La-teez @_lateez
13 Followers 157 Following Chemical biologist making bespoke science and tech designs #glycotime #chemistry #neurodivergent
Rupali Singh @RupaliS77891425
11 Followers 124 Following Incoming PhD student at NYU | MS Chemistry (IISER Mohali)
Engineer @Enginee21030126
25 Followers 208 Following
Ali Kheirandish @AliKheirandish4
133 Followers 3K Following
Grzegorz @Grzegorz_1997
2 Followers 30 Following
Gözde Begüm @Leafyy38
1 Followers 24 Following
Adeline Yong @adelineeyong
210 Followers 242 Following Synapses and activity • Postdoc Jan lab @UCSF • PhD @rhuganir lab @HopkinsNeuro
Andrew B. @blakezero8
20 Followers 88 Following
Deacon Michael Hogan @Deaconmike53
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Blockchain Virtuoso @BlockVirtuoso
27 Followers 69 Following Empowering individuals to take control of their financial futures 💪 Follow along as we leverage the power of blockchain and digital assets! #Empowerment
Melinda Alexáné Bab.. @blattarium
8 Followers 208 Following subject librarian for biology & chemistry @deenklibrary | zoologist - animal personality • collective behaviour • arthropods
S26 @DelphiBelle26
50 Followers 307 Following
Mehmet ÇINAR @mehmet_cinar_
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Laércio Barros #LIFE.. @LaercioBarross
7 Followers 325 Following Explorando a beleza e a grandiosidade da natureza em cada frame. Encante-se com os vídeos que capturam a essência selvagem do nosso mundo. 🌿🌍✨ #VídeosNatureza
Belen Sundberg @SundbergBelen
37 Followers 179 Following PhD candidate studying protein allostery @glasgow_lab @Columbia
みやした @emimimi_1206nyk
420 Followers 779 Following Kyoto Univ. d2 んぽちゃむグッズください。コーヒー/アイドル/ME:I/坂道とハロプロ/RNA
hanauta @hanauta39918848
15 Followers 46 Following 顕微鏡観察、絵本、Dale Chihulyの作品が好きです。 ぼーっとする時間を大切にしています😍
Gessie Anne Lopes MD @GessieAnneLopes
1K Followers 5K Following Médica Internista, Oncologista e Hematologista pela PUC/RS. Bacharelado em Filosofia UFRGS. Titular Especialista da SBC, ABHH e SBTMO.
Engel el Gozeriano �.. @promielocitico
96 Followers 2K Following Health defender of individual freedom, private property and equality before the law. Against all totalitarianisms. Islam outside Europe
🧚🏻♂️ @pixiegurllll
29 Followers 2K Following
Kornél Hevesi @KornelHevesi
0 Followers 23 Following
Sangyun Han @sangyun_han_
13 Followers 139 Following Post-bac researcher at Heo Lab, KAIST 🐥 🔎Optogenetics, CRISPR, and Molecular Neuroscience
Robinson Research Gro.. @CVR_Research
655 Followers 192 Following Twitter feed of Prof. Dame Carol Robinson's Research Group managed by her current group members @KavliOxford @OxfordChemistry
Kerisa @IsaKerisa
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hamidreza @haho1111111
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Catorose99 @catorose99
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Yak Deng @YDDeng12
26 Followers 211 Following
SANJAY @SANJAY01876685
2 Followers 41 Following
Heather Cooper @HeatherCoo37473
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Marco de Paulis @M_dp6000
1 Followers 24 Following
Reza Rohani @rezarohani_xyz
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Shu @Shu1421652
10 Followers 73 Following
Behnam Yousefi @behnam_bme
39 Followers 169 Following PostDoc Researcher in computational biomedicine at @UKEHamburg #ComputationalBiomedicine, #DeepLearning, #NetworkBiology
TopazStudios.com @TopazStudiosCOM
2K Followers 5K Following ONE chronic #illness to #disabled—follow @RenegadeRes—#longcovid #ckd #IgG #kidney #mecfs #pots #mcas #dysautonomia #pem #mitochondria $ltnc #lockdin #health
Bhaskar Maji @Bhaskar73401224
53 Followers 307 Following
Dr.Hussam @abdullah19471
466 Followers 3K Following PhD in Biochemistry, clinicl biochemistry and Molecular biology
Carolyn Bertozzi @CarolynBertozzi
77K Followers 3K Following Prof. @StanfordUChem; Baker Family Director, @Stanford_ChEMH; @HHMINews Investigator; EIC of @ACSCentSci; She/Her 🏳️🌈
Frances Arnold @francesarnold
65K Followers 774 Following Innovation by evolution, Linus Pauling Professor at Caltech, Nobel Prize in Chemistry (I am an engineer of the biological world)
David R. Liu @davidrliu
64K Followers 59 Following Professor at Harvard, Broad Institute, & HHMI. Our lab integrates chemistry & evolution to illuminate biology & enable new therapeutics. IG/Threads: @davidrliu1
Nature Biotechnology @NatureBiotech
302K Followers 2K Following Publishing the very best of biotech science and business. Part of @SpringerNature and @NaturePortfolio. On Facebook (natbiotechnol) & IG (nature.biotechnology)
Ingo Hartung @HartungIngo
14K Followers 780 Following MedChem @Merckgroup; drug discovery nerd in oncology, immunology & targeted protein degradation, soccer, politics or tapas can get into the way; my own views
Dan Nomura @DanNomura
17K Followers 9K Following Professor of Chemical Biology and Molecular Therapeutics at UC Berkeley; Departments of Chemistry and Molecular and Cell Biology
Craig Crews @CraigMCrews
9K Followers 1K Following Yale Professor, Founder of @ArvinasInc, https://t.co/YoR6Yo3d3u Mastodon account: @[email protected]
Jordan Meier @doc_jlmeier
4K Followers 670 Following Chemical biologist, basketball aficionado, proud homebody. My tweets are my own.
Guillaume Laconde @Glaconde34
4K Followers 115 Following Medicinal chemist, specialized on PROTAC and #TPD technology OXELTIS Scientist, https://t.co/F8c4eERuOA Communication Deputy for the SCT, https://t.co/8j34whJXIQ Tweets = my own.
Jay Bradner, M.D. @jaybradner
22K Followers 938 Following Physician-scientist making medicines with friends, memories with family. EVP R&D and CSO at Amgen
Stuart Schreiber @SchreiberStuart
11K Followers 367 Following Truth-seeking scientist; equal parts Cajun, Mississippian, Irish, Hungarian.
Covalent Modifiers @CovalentMod
4K Followers 348 Following A feed for the blog https://t.co/pXYAKACULR. Discusses the covalent modification of proteins. Available on bsky and mass std don
bryan dickinson @chembioBryan
6K Followers 1K Following chemical/synthetic biologist but generally motivated by making molecules that do stuff, dad, @uchicago professor of chemistry
Jeremy Baskin @basktastic
5K Followers 1K Following Click chemist, cell biologist, #chembio & #lipidtime enthusiast, occasional classical pianist (he/him). Also @[email protected]
ChemBioChem @ChemBioChem
11K Followers 2K Following Rapid. Fair. Unbiased. Core journal for breakthroughs across all areas at the interface of chemistry & biology. #ChemBioTalents. Published by @ChemEurope.
Marnix Medema @marnixmedema
6K Followers 2K Following Professor of Bioinformatics at Wageningen University, Visiting professor at Leiden University. Natural product discovery, microbiomes, method development.
drug hunter @drughuntersite
9K Followers 23 Following the science of drug discovery, distilled for industry innovators. discover more by subscribing at: https://t.co/FnfsOmSXe4
Olalla Vázquez @OlallaLab
7K Followers 4K Following Professor of Chemical Biology at @Uni_MR. Optochemical tools for controlling biological processes at molecular level. Epigenetic chemical probes. Be Light!✨✨
Dirk H. Trauner @DirkTrauner
16K Followers 12K Following Penn Integrates Knowledge Professor, Natural Product Aficionado, Photopharmacologist, Fox Terrierist, and Unfulfilled Architect. #firstgen
Nature Reviews Clean .. @natrevcleantech
189 Followers 92 Following Reviewing and amplifying clean technology research, from science to society. Launching in January 2025 from the Nature Portfolio.
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698 Followers 479 Following Chemically dissecting host-microbe interactions @MCDB_Yale. Tweets by lab members.
Russell Johnson @RussJKJohnson
2K Followers 1K Following Chief Editor for @nchembio so chemistry/chemical biology/biomaterials tweets dominate. Views my own etc… (he/his) @[email protected]
Kohli Lab @KohliLab
648 Followers 260 Following Studying DNA-modifying enzymes & pathways that add complexity to genomes. Tweets crowdsourced from overworked lab members & not Rahul Kohli unless tagged #RMK.
Daniel Heller @Dan_A_Heller
4K Followers 3K Following Head of the Cancer Nanomedicine Laboratory at Memorial Sloan Kettering Cancer Center and Weill Cornell Medicine. All opinions are my own.
Liron Bar-Peled @LironBarPeled
1K Followers 356 Following studying intersection of signaling, metabolism and chemical biology Asst professor @MGHCancerCenter and @harvardmed
The Hackenberger Grou.. @PhosphorusFive
2K Followers 406 Following We are a Berlin-based #chemicalbiology group thrilled about modifying proteins to advance biological research and drug development.Also known as the Hackenbees!
Ville Paavilainen �.. @v_paavilainen
901 Followers 743 Following Group leader at the Institute of Biotechnology @helsinkiuni. My lab studies ER proteostasis modulating natural products.
Aditya Kunjapur @kunjapur
3K Followers 3K Following Assistant Professor @UDChBE @UDelaware | Expanding the repertoire of microbial chemistry and sending positive vibes | #synbio https://t.co/4VVWd3IuKj
Park Lab at UC Berkel.. @EParklab
292 Followers 80 Following lab of Prof. Eunyong Park at @berkeleymcb @QB3Berkeley using biochemistry&cryo-EM to study mechanisms of protein transport and quality control pathways
Gary Patti @gjpattij
842 Followers 204 Following metabophile ( muh-tab-uh-fīl′ ) : a person obsessed with all things metabolism, metabolomics
Rohit V. Pappu @PappulabWashU
5K Followers 544 Following Pappu Lab at Washington University in St. Louis
Ed Chouchani @echouchani
3K Followers 326 Following Faculty @DanaFarber @HarvardCellBio Co-founder @matchpointtx
X David Li Lab @XDavidLiLab1
666 Followers 213 Following Professor in HKU Chemistry. Epigenetics and Chemical Biology.
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Yi Tang @yitang_ucla
1K Followers 165 Following Professor, UCLA. EIC, Journal of Industrial Microbiology and Biotechnology.
Paolo De Los Rios @PaoloDeLosRios
998 Followers 666 Following Private account. Statistical and Biological Physics @ EPFL. My opinions (the few I have) are mine. Non-equilibrium and ML enthusiast.
Matt Volpe 🏳️.. @MatthewRVolpe
312 Followers 489 Following Scientist @ConcertoBio, former Financial Secretary @hgsuuaw, theater kid, Enthusiastic (though occasionally misguided) baker | he/him/his
Rachelle Gaudet @RachelleGaudet
1K Followers 618 Following Structural Biologist, Lindy Hop fanatic and amateur nature photographer. On Mastodon @[email protected]
BMJMedicine @BMJMedicine
19K Followers 197 Following A new #openaccess journal from #TheBMJ for specialist research that promotes multidisciplinary collaboration to improve the health of patients
Pat Sharp @PatSharpChem
546 Followers 1K Following Scientific co-founder Gate Bio | curing disease | prev: @Merck medicinal chemistry
Nature Outlook @NatureOutlook
11K Followers 682 Following Nature Outlooks are supplements to Nature, filled with infographics, features and comment about issues of scientific interest.
⌬Nessa Carson @SuperScienceGrl
17K Followers 3K Following Digital chemist | "Aggressively sciency'' | Buchwald-Hartwig = best reaction | Making lab science faster and better | She/her
J. Fernando Bazan @jfernandobazan
726 Followers 2K Following biotech catalyst+connector / cracks struc puzzles! / protein deep-folding & engin 4 bioTx+drug disco / molec recognition+signal mechs in cytokine/R sys / Tico!
Gilles Gouspillou @GGouspillou
1K Followers 941 Following Scientist interested in skeletal muscle physiology, mitochondrial biology and aging.
Bioga @BiogaGalicia
2K Followers 648 Following Cluster Tecnolóxico Empresarial das Ciencias da Vida de Galicia
Stuart Cantrill @stuartcantrill
21K Followers 3K Following Wine, chemistry, words & snark. Husband, Dad, Editorial Director (@NaturePortfolio) & pedant. Views ranty, but all mine. He/Him. https://t.co/YXJud9BVJ4
James Butcher @Journalologist
2K Followers 1K Following I help editors and publishers create impactful journals. Ex Lancet. Ex Nature Portfolio. Best years are ahead of me.
Ardem Patapoutian @ardemp
51K Followers 300 Following @scrippsresearch Professor. @HHMINEWS Investigator. @NobelPrize Physiology or Medicine 2021. Research: touch & other forms of pressure sensing
Tom Grossmann @TomNGrossmann
2K Followers 494 Following Chemistry professor @VUamsterdam (my views) #peptidomimetics | #proteomimetics | #incypro | co-founder #incircular
Ellie Kincaid @ellie_kincaid
2K Followers 659 Following Editor, @RetractionWatch. Previously: WebMD/Medscape, Forbes, WSJ. Tips: [email protected]
Chemjobber @Chemjobber
45K Followers 6K Following 1. A blog 2. Towards a quantitative understanding of the quality of the chemistry job market | #chemjobs: permanent industry/academia, #chempostdoc: postdocs
Buck Samuel @microbeMinded
3K Followers 5K Following organismal biologist | PI @BCM_Microbiome | continually amazed by microbes and their superpowers | #microbiome #Celegans | he/him (@microbeMinded.bsky.social)
Kelly Nguyen @KellyTHD_Nguyen
5K Followers 1K Following Group Leader @MRC_LMB /Structural Biologist/Biochemist. Amateur baker in free time #RNAworld #spliceosome #telomerase #telomeres #cryoEM #Xraycrystallography
Hojong Yoon @hojong_yoon
673 Followers 278 Following NCI K99/R00 postdoc @broadinstitute @DanaFarber | PhD @Harvard @DFCI_ChemBio | BS @SNU_pharm | Protein degradation, Induced proximity, Drug discovery
Katherine A Donovan @kdonovan1008
2K Followers 368 Following 🇳🇿 Kiwi | Scientist @DanaFarber @harvardmed | Targeted Protein Degradation | Chemoproteomics | Tweets are my own.
Johnson Lab UNC @JohnsonGroup
2K Followers 251 Following Student-run Twitter page for Jeffrey Johnson’s lab at UNC Chapel Hill | Cutting-edge Catalysis and Natural Products Synthesis
Sarah Reisman @sarah_reisman
18K Followers 871 Following Bren Professor of Chemistry @Caltech| AE at JACS|Editorial Board @OrgSynth|Organic chemist and mom|Views are my own|she/her
Cell Stem Cell @CellStemCell
56K Followers 69 Following A monthly journal at the forefront of stem cell science and policy. Posts & opinions from Editor-in-Chief, Dr. Sheila Chari
PLOS @PLOS
158K Followers 12K Following #Mastodon - @[email protected] Breaking boundaries. Empowering researchers. Opening Science.
Dr Laura Sanchez @DrLauraSanchez
4K Followers 2K Following I am a Scientist. #imaging #massspec #biofilms 🧫 #microbialcommunities 🧀 #ovariancancer 💊 Associate Professor Chemistry and Biochemistry @ucsc she/her
Communications Chemis.. @CommsChem
6K Followers 1K Following An open access @NaturePortfolio journal publishing high-quality primary research articles, reviews and commentary in all areas of the chemical sciences.
EMBO @EMBO
36K Followers 1K Following European organization of 2,000+ researchers that promotes excellence in the life sciences and helps to build a thriving research environment
Genome Biology @GenomeBiology
93K Followers 486 Following Tweets about latest articles in the journal Genome Biology, conferences & more. Part of @SpringerNature. Also read our blogs (https://t.co/7GgHTUIKaX).
The SGC Frankfurt @thesgcfrankfurt
429 Followers 151 Following At SGC Frankfurt we develop selective inhibitors for the validation of new targets. We share our science with the community!
Brennan Group @GroupBrennan
992 Followers 427 Following News and updates from the Brennan Group. Part of the Centre for Medicines Discovery Oxford and the ARUK Oxford Drug Discovery Institutue.
Scripps Research @scrippsresearch
237K Followers 538 Following Scripps Research is one of the world's largest, private, non-profit biomedical research organizations. We are Science Changing Life.
We are super excited that our review on the sulfated metabolome is online in @nchembio today! Led by Gabriel and Snehal in the lab. Check it out! nature.com/articles/s4158…
Learned this weekend— on International Women and Girls in Science Day, nonetheless— that I was promoted to Full Professor!
Nothing like that 1st day feeling! @UFScripps !!
@Chrizzly_92 @eventuallyptrck We would like to thank @nchembio, Nicole Paczia from the @mpi_marburg metabolomics core facility and the whole @erblabs for support!
If you ever wondered how many purified enzymes work together in one pot, the answer is yes! Happy to share one of the last stories from my work in the @erblabs. Big thanks to first author @eventuallyptrck, @nchembio, Nicole Paczia (# notwitterhandle) and last but not least Tobi!
A new paper from @erblabs, @Chrizzly_92, @eventuallyptrck enabled a 54-step in vitro biosynthesis of the macrolide backbone of the antibiotic erythromycin from CO2. Open access: nature.com/articles/s4158…
Not official until the end of the year, but delighted to hear my department has voted in favor of promoting me to full professor! So grateful for my amazing students and collaborators, and family, that have made the science so enjoyable to do!!!
Speaking after the #NobelPrize announcement, Carolyn Bertozzi, one of the three winners, said this is just the beginning: “I think the field of click chemistry is still in its early stages. There’s probably many new reactions to be discovered.” nature.com/articles/d4158…
BREAKING NEWS: The Royal Swedish Academy of Sciences has decided to award the 2022 #NobelPrize in Chemistry to Carolyn R. Bertozzi, Morten Meldal and K. Barry Sharpless “for the development of click chemistry and bioorthogonal chemistry.”
Thrilled to be awarded an NIH Director's New Innovator Award! commonfund.nih.gov/newinnovator/A…
A new drug designed by scientists at @scrippsresearch turns the #COVID19 virus into a harbinger of its own doom. NMT5, described in @nchembio, coats SARS-CoV-2 with chemicals that alter the ACE2 receptor, blocking its entry into human cells. scripps.edu/news-and-event…
New paper in @nchembio showing that bile acids bind and inactivate an intracellular virulence regulator (HilD for the aficionados) in Salmonella. Check it out... rdcu.be/cWEWO
My @scrippsresearch colleagues just published @nchembio a new oral drug vs Covid that blocks ACE2 binding to the spike protein, inhibiting viral entry and infections in the experimental model nature.com/articles/s4158…
Regulation of human cells, based on external or physiological molecules, enables safer and more effective therapy. Ideally, #syntheticbiology tools should use endogenous human proteins & approved drugs. We present the INSPIRE platform @nchembio rdcu.be/cWmMN 1/5
Today we report in @nchembio the discovery and molecular basis of the first reported subtype-selective cyclophilin inhibitors. This work was a collaboration with the labs of Markus Seeliger and @VamsiMootha. drive.google.com/file/d/1HgJuxl… 1/9
Important resource for anyone interested in developing AI-based drug discovery - Therapeutics Data Commons (TDC), a collection of AI-solvable tasks, AI-ready datasets and curated benchmarks. Description published in @nchembio. nature.com/articles/s4158…
We can finally share our exciting collaborative work with @BurkeLabRNA and Heng Lab out today in @nchembio supported by NASA Exobiology and an ongoing Interdisciplinary Consortium in Astrobiology Research (ICAR) award! nature.com/articles/s4158…
So thankful to see that our paper leveraging non-neutralizing antibodies into broad-spectrum inhibitors for SARS-CoV-2 is now online in @nchembio! It has some fun updates, including that these ReconnAbs neutralize BA.2 and live virus! nature.com/articles/s4158…
Molecular makeover makes wimpy antibody a #SARS-CoV-2 tackler @nchembio doi.org/gqscxr phys.org/news/2022-09-m…
New in @nchembio: ReconnAbs neutralize #Omicron, including in experiments with live SARS-CoV-2 virus—research illustrating their therapeutic potential against COVID & other diseases. nature.com/articles/s4158…
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