Marnix Medema @marnixmedema
Professor of Bioinformatics at Wageningen University, Visiting professor at Leiden University. Natural product discovery, microbiomes, method development. marnixmedema.nl Wageningen, The Netherlands Joined February 2010-
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Wouldn't it be nice to do complex #NatualProducts #GenomeMining analyses on large datasets with hundreds or thousands of genomes? With #BGCFlow, we may have a solution for you: academic.oup.com/nar/advance-ar… [1/4]
Thanks for the superb hospitality! Was great to catch up with you, your team and your colleagues!
Thanks for the superb hospitality! Was great to catch up with you, your team and your colleagues!
Great to see @elena_delpup & @rosina_to participating in the @mzmine_project #workshop taking place in Prague this week! We also have Niek de Jonge there to explain #matchms and #MS2Query! 😎 #CompMetabolomics #metabolomics #massspectrometry
Great to see @elena_delpup & @rosina_to participating in the @mzmine_project #workshop taking place in Prague this week! We also have Niek de Jonge there to explain #matchms and #MS2Query! 😎 #CompMetabolomics #metabolomics #massspectrometry
Early train to Berlin for undoubtedly an intense and fun workshop on plant microbiomes hosted by the Max Planck Gesellschaft @maxplanckpress
New Scientific Director is being seeked at our institute, @LeidenBiology 🇳🇱 deadline 25 April 2024 -please share with your network universiteitleiden.nl/en/vacancies/2…
Job Alert! Join our group as a postdoc @LUCID_LUMC to unravel the mysteries of tumor-microbiome interactions. For details, see lumc.nl/en/about-lumc/… or contact us directly!
Very nice work by Nataliia Machushynets, and great @NWO_TTW NACTAR team work with Karol and @BDragonMaster on combining genome mining, metabolomics, bioactivity screening and chemical synthesis.
Very nice work by Nataliia Machushynets, and great @NWO_TTW NACTAR team work with Karol and @BDragonMaster on combining genome mining, metabolomics, bioactivity screening and chemical synthesis.
How to pick a problem. Today in @CellCellPress. 1/53 cell.com/cell/fulltext/…
Interested in natural product biosynthesis? Working on tailoring enzymes but frustrated by the lack of a dedicated repository? Us too! That’s why we created MITE – the Minimum Information about a Tailoring Enzyme doi.org/10.26434/chemr…
Exciting GIM meeting in Shanghai coming up this fall: gim-mes2024.org The website is now live and registration open. @tilmweber and I will be chairing a session on AI for Biotechnology/Synthetic Biology.
Our paper on #Logomotif is out in @JMolBiol, a database for transcription factors in #Actinobacteria. Only well curated TFs included, but version 2 is in the planning. Awesome work by @HannahAugustijn with @marnixmedema @SebaRigali and colleagues. sciencedirect.com/science/articl…
We are hiring: PhD student - Machine learning in plant regulatory genomics, Ghent VIB-UGent Center for Plant Systems Biology. More info at vandepoelelab.be/Jobs
We are hiring: PhD student - Machine learning in plant regulatory genomics, Ghent VIB-UGent Center for Plant Systems Biology. More info at vandepoelelab.be/Jobs
One week to go!
Our paper on the nanoRAPIDS platform is out in @CommsChem. The analytical pipeline nanofractionates 10 ul complex culture extract into 384 wells and then determines high-res mass and bioactivity of all peaks. doi.org/10.1038/s42004…
Highly relevant @ISMEJournal review for the SynCom enthusiasts by Jiayi Jing, @PaolinaGarbeva, @RaaijmakersJM and @marnixmedema Strategies for tailoring functional microbial synthetic communities academic.oup.com/ismej/advance-…
It was great fun putting this together, spearheaded by Jiayi, who is also doing amazing stuff with SynComs in the lab/greenhouse at the moment... This paper discusses comp. design principles, with a focus on better utilizing functional traits, in feedback loops with experiments.
It was great fun putting this together, spearheaded by Jiayi, who is also doing amazing stuff with SynComs in the lab/greenhouse at the moment... This paper discusses comp. design principles, with a focus on better utilizing functional traits, in feedback loops with experiments.
On the fourth day of the @lorentzcenter workshop on Deciphering Microbiome Functions, @Neha10GT explains how to use metabolomics to identify the roles of molecules in microbiome interactions.
We are hiring! PhD position in collaboration with WUR Host-Microbiome Interactomics and WFBR. The candidate will develop and apply machine-learning algorithms to predict substrate specificities of carbohydrate-acting enzymes from gut bacteria. academictransfer.com/nl/339425/phd-…
one important reason we haven't reached an "alphafold moment" for biological data beyond protein structures: datasets for protein structure are consistent and uniform. x-ray crystallography or cryo-EM data provide absolute atomic coordinates, meaning that the data is…
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Justin van der Hooft @jjjvanderhooft
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Pieter Dorrestein @Pdorrestein1
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Dr Katherine Duncan @kate_duncan
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Max Planck Institute .. @MPI_CE
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VanDerHooft_CompMetab.. @vdHooft_CompMet
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Giannis Stringlis @GStringlis
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Pablo Iván Nikel @pa.. @PabloINik
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Nadja Cech @nadjacech
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Chenxin Li, PhD (@che.. @ChenxinLi2
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Kathrin Wippel @kathywippel
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Aoyang Chen @aoyangchen
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Darren Holland @holland_dch
150 Followers 239 Following Postdoctoral Research Associate | Chooi Group | School of Molecular Sciences | The University of Western Australia
Lauren Murray @laurenammurray
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NPGMgroup @NPGMgroup
18 Followers 13 Following We build tools, platforms, cell factories and we love Actinomycetes and their natural products!
Vanessa R Marcelino @hologenomics
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78 Followers 124 Following PhD student, Link Lab, Princeton University; Bacterial natural products; Ribosomally synthesized and post-translationally modified peptides (RiPPs); Graspetides
Drew Carson @DrewCarson712
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Seppe Kuehn Lab @SeppeKuehnLab
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Carlos N. Lozano-Andr.. @neftalyl
712 Followers 3K Following Postdoctoral researcher at DTU Bioengineering exploring the natural role of secondary metabolites produced by B. subtilis | 🇨🇴🇬🇦|
Aleksandra Kushnareva @AlexKushnareva
15 Followers 52 Following PhD at @Saar_Uni | Member of @gurevichlab group at @Helmholtz_HIPS | Microbial genome mining, (phylo/meta)genomics #bioinformatics #naturalproductdiscovery
Lisa Vader @lisavader99
29 Followers 34 Following
Dora Ferreira @DoraMFerreira
55 Followers 153 Following PhD candidate at #Naicons and @MAGicMOLFUN, working to discover new natural products 🧫👩🏻🔬
Annette Lien @LienAnnett21449
31 Followers 15 Following PhD student @WUR, bioinformatics for natural product discovery
Luca Salvi @lucasalviii
33 Followers 38 Following PhD student, University of Tübingen, Germany. Microbial natural products researcher 🧫🔬
Adriana Romero Otero @AdrianaRomeroOt
29 Followers 72 Following Chemistry ⚗️🧪 fungi 🍄🧫 nature and food lover
Judit Szenei @JudSzn
29 Followers 96 Following @MAGicMOLFUN Doctoral Candidate at @DTUBiosustain 🧩 Currently busy with halogenases (she/her)Wouldn't it be nice to do complex #NatualProducts #GenomeMining analyses on large datasets with hundreds or thousands of genomes? With #BGCFlow, we may have a solution for you: academic.oup.com/nar/advance-ar… [1/4]
Great to see the work of our team (including @DPortik, @itzhak_mizrahi, @ivanliachko , @PacBio, @tplsmith, @MishaKolmogorov, @marnixmedema, and many others) highlighted in this excellent review!
Review paper out today @naturemethods on long-read #sequencing for #metagenomic: rdcu.be/dGeIj Great advancements on utility of @nanopore @PacBio forming novel insights in diversity and resolution. Great work by @D_Agustinho @fuyvei96 @traingene @BCM_HGSC @RiceCompSci
How can lab automation, machine learning, and high-throughput screening methods be combined to speed up the enzyme engineering process? We address this question in a new article in @NatureComms, out today: nature.com/articles/s4146…
📢This month's issue has an inside front cover from Wei Zhang & co @ShandongU on the biosynthetic logic and enzymatic machinery of approved fungi-derived pharmaceuticals and agricultural biopesticides Don't miss the full review on our website🔽 pubs.rsc.org/en/content/art…
Woah! 🤯 An isoprenoid that is prenylated with a prenylated prenyl group.
A unique cuticular hydrocarbon from the springtail Heteromurus nitidus. This new terpene type, a prenylated geranylated diterpene, highlights differences between Collembola and more advanced insects. See our article in J Nat Prod. doi.org/10.1021/acs.jn…
Although unfortunate reason to be home - I did get to spend some time with my dad for koningsdag - kings day.
Today at the Impostor Syndrome Workshop by @ana_pineda_ offered by @WUR Graduate Schools I found out about the HIGH5 strengths test high5test.com Here are my Top 5 Strenghts! test.high5test.com/test/ODSDGPW9S…
1. Believer 2. Catalyst 3. Self-Believer 4. Chameleon 5. Phylomath
Please join the group! We work on all aspects on plant specialised metaboism including gene discovery, biosynthesis, evolution and even applications e.g. biocatalysis and SynBio
Announcing the 2024 #MSCA calls! 🧑🔬🧬🔭🧑💻🚀 This year, €1.25 billion will support: 🟣 Doctoral & postdoctoral programmes 🟣 Collaborative research projects 🟣 Employment & training for up to 10,000 researchers! Help us make 🇪🇺 science and R&I shine! Apply today 🙌 1/4 🧵⤵️
Many to be grateful to! My mom, mentors, students, colleagues, Georgia Tech, collaborators, reviewers, letter writers, funding agencies and my seminar hosts! Thank you all! Humbled to be promoted to Associate with tenure! You all made a difference. This is your promotion too🍾🎉
#Congrats | @GTSciences faculty awarded tenure -Alex Blumenthal, School of Mathematics -Neha Garg @GT_CHEM -Gongjie Li, School of Physics -Jesse McDaniel @GT_CHEM -Alexander Robel @GeorgiaTechEAS -D Zeb Rocklin, School of Physics -Alberto Stolfi @GTBiology faculty.gatech.edu/celebrating-te…
A decade or two ago we could only dream of having genomes for all species of a major branch of the tree of life. Thanks to the Y1000+ Project, the dream is now reality! Kudos to @HittingerLab @DOpulente @Lab_LaBella @MarizethGroene1 & the whole TEAM science.org/doi/abs/10.112…
I'm glad to have contributed to this new preprint from @OConnor_lab! In this preprint, we look at how specialized metabolites are distributed across single cells across different organs using single cell metabolomics. 1/n biorxiv.org/content/10.110…
Got my personal copy of the "Most Delicious Poison" by @NKWhiteman. This masterpiece delves into the fascinating #naturalproducts of #plants/#fungi/#microbes and explores how animals have adapted to combat them. Can't wait to dive into its pages #coevolution #plantinteraction
Thanks @marnixmedema for making the trip to Tuebingen and giving an inspiring talk at the #IBMI symposium! To many more years of collaborative science together!
@PabloCruzMoral1 @AnnualReviews @AgusUndabarrena I hope everyone enjoys our article!!!!!
Sandra and I got married 25 years ago 💕
fantastic to have @BradMoore_SIO and family visiting in Leiden. This afternoon we went to see the beautiful flowerparade #bloemencorso
I might be biased, but Streptomyces are pretty cool: They not only make lots of antibiotics but also secrete umbrella toxins to interact with their microbial neighbours. Streptomyces umbrella toxin particles block hyphal growth of competing species nature.com/articles/s4158…
use of the plant extract library by @NatMart_Chembio to screen for bioactive molecules. Great story at the annual symposium @LeidenBiology
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