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Biochemistry @BiochemistryACS

An international forum for publishing exceptional, rigorous, high-impact research across all of biological chemistry. EIC: @AlannaSchepartz, @UCBerkeley pubs.acs.org/biochemistry Joined March 2016
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Biochemistry @BiochemistryACS

15 hours ago

Crowding agents are used to mimic intracellular environments, capturing biomolecules in more native conditions. Liebau et al. study the impact of different PEGs on tRNA synthetase, finding disparate impacts depending on length. pubs.acs.org/doi/10.1021/ac… @UWEC_chem @OhioState

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Biochemistry @BiochemistryACS

2 days ago

Consensus sequences are used extensively to predict protein function. Musila and Rokita offer a cautionary tale re this practice in their analysis of FMN-binding & catalytic residues in nitroreductases. pubs.acs.org/doi/10.1021/ac… #tbt @JHUArtsSciences @JohnsHopkins #flavins

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Biochemistry @BiochemistryACS

3 days ago

Photosynthesis pathways: Quinone herbicides binding to type-II reaction centers of purple bacteria suggest a QB-mediated link between the electron transfer inactive branch and the proton uptake pathway. From Ishikita and colleagues @UTokyo_News_en pubs.acs.org/doi/10.1021/ac…

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Biochemistry @BiochemistryACS

4 days ago

Halting headaches: Does the amylin 1 receptor play a role in migraines? @PatrickMSexton, Wootten & colleagues report a #cryoEM structure of AMY1R with the peptide CGRP & Gs protein, revealing new insights. pubs.acs.org/doi/10.1021/ac… @CCeMMP @MIPS_Australia @UTokyo_News_en #GPCR

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Biochemistry @BiochemistryACS

5 days ago

19F NMR tools: Zondlo and colleagues show that 4,4-difluoroproline is a broadly applicable tool for monitoring Pro conformation with applications in protein folding, intramolecular interactions and intrinsic disorder. pubs.acs.org/doi/10.1021/ac… #folding #disorder @UDelaware

BiochemistryACS Profile Picture

Biochemistry @BiochemistryACS

5 days ago

📢 Call for Papers! Biased Signaling is an upcoming Special Issue in Biochemistry organized by Executive Editor Bryan Roth (@zenbrainest) Learn more here and get your research seen by the global #Biochemistry community ➡ go.acs.org/91r

Biochemistry retweeted
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ACS Synthetic Bio @ACSSynBio

a week ago

Make sure you check out the fantastic artwork on the Issue #4 front cover! Learn the significance of this work in Kwanwoo Shin's Editorial in #ACSSyntheticBiology ➡️ go.acs.org/8Zr "Scientific progress relies on the maxim that scientific inquiry knows no bounds" 🤩

BiochemistryACS Profile Picture

Biochemistry @BiochemistryACS

a week ago

How does a mixed-valent diiron oxygenase help in the #biosynthesis of a copper chelator? @RosenzweigLab, Hoffman and colleagues @NorthwesternU use ENDOR to look at substrate binding, revealing the initial steps toward methanobactin. pubs.acs.org/doi/10.1021/ac… #bioinorganic

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Biochemistry @BiochemistryACS

a week ago

CO2 impacting signaling: Pawloski et al expand on initial reports of ubiquitin carbamylation, testing susceptibility of all amines & finding candidates that likely affect polyUb-mediated pathways in cells. pubs.acs.org/doi/10.1021/ac… #tbt #PTM @UofMaryland @JHUArtsSciences

BiochemistryACS Profile Picture

Biochemistry @BiochemistryACS

a week ago

Aldehyde dehydrogenases are of interest in understanding disease and #biocatalysis. Soulimane, @luismpadrela and colleagues @UL examine an unusual C-terminal extension found in thermophilic ALDHs, finding impacts on kinetics, stability & specificity. pubs.acs.org/doi/10.1021/ac…

Biochemistry retweeted
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American Chemical Society @AmerChemSociety

2 weeks ago

Did you know that the world’s deadliest animal is the #mosquito? A path towards new super-specific insecticides takes advantage of the unique biochemistry of mosquito larvae guts, as published in @J_A_C_S. Read more: brnw.ch/21wIQxE @ACSPublications #Research

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Biochemistry @BiochemistryACS

2 weeks ago

New issue! 📣 Read up on enhanced antibodies, microsatellites, proteasomes, ethylene formation, chitin production, and more! pubs.acs.org/toc/bichaw/63/8 Cover image: Auchus and colleagues @UMich explore how P450 11B2 catalyzes 3 consecutive oxidations. pubs.acs.org/doi/10.1021/ac…

BiochemistryACS Profile Picture

Biochemistry @BiochemistryACS

2 weeks ago

A three-continent collaboration explores the potential convergent evolution of glucanases, critical for grain germination in barley. pubs.acs.org/doi/10.1021/ac… #glycotime #plantbiochemistry #proteinevolution @KTHuniversity @TaipeiMedicalU @UniofAdelaide @IBMResearch @AucklandUni

BiochemistryACS Profile Picture

Biochemistry @BiochemistryACS

2 weeks ago

ICYMI: @SaSa10447 et al unravel the catalytic mechanism of an important antioxidant enzyme from M. tuberculosis, revealing how sulfoxides are reduced. Now an #ACSEditorsChoice paper! pubs.acs.org/doi/10.1021/ac… #mycobacteria

BiochemistryACS Profile Picture

Biochemistry @BiochemistryACS

2 weeks ago

Toward plastic recycling: @CourtadeGaston and colleagues characterized a PET-hydrolyzing cutinase from Fusarium solani pisi, revealing opportunities to improve enzyme activity and tune degradation products. pubs.acs.org/doi/10.1021/ac… #biocatalysis #tbt @NTNU @aalborg_uni

BiochemistryACS Profile Picture

Biochemistry @BiochemistryACS

2 weeks ago

📢 Call for Papers! Biased Signaling is an upcoming Special Issue in Biochemistry organized by Executive Editor Bryan Roth (@zenbrainest) Learn more here and get your research seen by the global #Biochemistry community ➡ go.acs.org/8R1

BiochemistryACS Profile Picture

Biochemistry @BiochemistryACS

2 weeks ago

The enzyme EFE can form ethylene or hydroxylate Arg (en route to guanidine), both of biotechnological interest. Chatterjee et al use substrate analogs and mutants to dig into active site interactions, enabling future applications. pubs.acs.org/doi/10.1021/ac… #metalloenzymes

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Biochemistry @BiochemistryACS

3 weeks ago

Cell death mechanisms: Zhu and colleagues @CUHKofficial show 4-hydroxyestrone protects against ferroptotic cell death and binds to protein disulfide isomerase, providing further support that PDI is a meaningful target to prevent ferroptosis. pubs.acs.org/doi/10.1021/ac… #cancer

BiochemistryACS Profile Picture

Biochemistry @BiochemistryACS

3 weeks ago

📢Call for Papers!📢 #Biochemistry is putting together a Virtual Special Issue Guest edited by Albert Bowers and Roberto Kolter to honor the late Christopher T. Walsh and the current research inspired by his work. More information ➡ go.acs.org/8OO

BiochemistryACS Profile Picture

Biochemistry @BiochemistryACS

3 weeks ago

Recent results are helping to understand how PI31 inhibits the 20S #proteasome, but how general are these results? Wang, Kjellgren & DeMartino test PI31's ability to inhibit additional forms, finding surprising differences. pubs.acs.org/doi/10.1021/ac… @UTSWMedCenter #proteostasis

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