Rachel Harding @LabScribbles
Principal Investigator Huntington's Disease Research @TheSGCOnline, Assistant Prof Dept Pharmacology & Toxicology @UofT, Editor-in-chief @HDBuzzFeed, she/her labscribbles.com Toronto, Ontario Joined December 2015-
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Rachel Harding retweeted
We couldn't be prouder of @LabScribbles who joined @UofTPharmacy as an Assistant Professor! Please join us in congratulating Dr. Harding on this remarkable achievement! 📲 thesgc.org/news/dr-rachel…
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Rachel Harding retweeted
We're pleased to welcome Assistant Prof. Rachel Harding (@LabScribbles) to the Department of Pharmaceutical Sciences at UofTPharmacy! Prof. Harding's research aims to unravel the complexities of Huntington’s disease & forge new paths for therapeutics 📖⬇️ pharmacy.utoronto.ca/news-announcem…
Rachel Harding retweeted
Huntingtin is an RNA binding protein and participates in NEAT1-mediated paraspeckles pubmed.ncbi.nlm.nih.gov/39028820/ Awesome study by Manisha Yadav, @LabScribbles , @pouladi , @hansenhe7 and Pearson Labs
Rachel Harding retweeted
@LabScribbles was recently honored with the @hdfcures Nancy S. Wexler Young Investigator Prize. The foundation has also provided funding to support Dr. Harding's research on the interaction between the Huntingtin protein and HAP40. thesgc.org/news/dr-rachel…
Rachel Harding retweeted
A win for @thesgconline’s Rachel and her scientific and #openscience leadership!
A win for @thesgconline’s Rachel and her scientific and #openscience leadership!
Rachel Harding retweeted
We are proud of our very own @LabScribbles! Rachel has been working on #HuntingtonsDisease at SGC-Toronto with a strong ethos of #OpenScience and collaboration. Congratulations, Rachel, on this well-deserved recognition!
We are proud of our very own @LabScribbles! Rachel has been working on #HuntingtonsDisease at SGC-Toronto with a strong ethos of #OpenScience and collaboration. Congratulations, Rachel, on this well-deserved recognition!
Rachel Harding retweeted
Now peer-reviewed: rdcu.be/dJ7IY ... and just funded by a 5-year #CIHR grant to see with @fgentile9,@LabScribbles,@thesgconline, @chem4biology and a growing number of chemistry labs what this expanding non-commercial chemistry space can do for hit finding.
Now peer-reviewed: rdcu.be/dJ7IY ... and just funded by a 5-year #CIHR grant to see with @fgentile9,@LabScribbles,@thesgconline, @chem4biology and a growing number of chemistry labs what this expanding non-commercial chemistry space can do for hit finding.
Rachel Harding retweeted
Today is the International Day of #HuntingtonsDiseaseAwareness. Read more about the recent visit of the @HuntingtonSC to the SGC. Families saw firsthand the progress of @LabScribbles' group in #HDResearch. ▶️thesgc.org/node/1649788
Rachel Harding retweeted
How benchmarking challenges and data in the public domain will guide development in AI-based methods and breakthroughs in #drugdesign on a scale analogous to that seen for protein fold prediction? @mattschap @LabScribbles @CherylArrowsmi1 @HalabelianLab nature.com/articles/s4158…
Rachel Harding retweeted
Through #OpenScience collaborations, we make our research outputs available to the scientific community with no strings attached. If you haven't already, check @LabScribbles and @CherylArrowsmi1 last preprint on #Huntingtonsdisease biorxiv.org/content/10.110…
Rachel Harding retweeted
In-depth perspective on the first CACHE challenge in @NatRevDrugDisc nature.com/articles/d4157… #compchem @thesgconline @consciencemeds
Rachel Harding retweeted
A new study demonstrates for the first time the ability of Huntingtin protein to directly bind to RNA species. Read our preprint and learn more about the role of a specific RNA, called NEAT1, in connecting with Huntingtin within cells. 📰 biorxiv.org/content/10.110…
Rachel Harding retweeted
CACHE#1 results are in: bit.ly/48zjBhI. No prior ligand for the target. 1955 compounds predicted by 23 experts. 7 convincingly confirmed experimentally. This is the state-of-the-art. Exploration of modern AI techniques in 6 of the 7 top performing methods. #compchem
Rachel Harding retweeted
"A protein implicated in a disease, remains a lock without a key unless a molecule can be found to bind to it and deter its harmful effects". Glad to see @globeandmail featuring CACHE Challenges in their piece on AI-guided #drugdiscovery. @consciencemeds theglobeandmail.com/canada/article…
Rachel Harding retweeted
@mattschap, @LabScribbles and Derek Wilson identified a chemical handle that binds to USP3 without affecting its normal function. This compound provides a foundation for future USP3-recruiting DUBTACs to rescue targets from proteasomal degradation. pubs.acs.org/doi/10.1021/ac…
Rachel Harding retweeted
Announcing the 5th CACHE challenge. Predict novel antagonists for MCHR1, a GPCR with no structure in the PDB but hundreds of known ligands... Compounds will be tested in Bryan Roth @zenbrainest lab at UNC and results published. Apply by Feb 14th. bit.ly/484U7Zi #compchem
Rachel Harding retweeted
Steady progress from uniQure - promising data to end the year - ift.tt/aqYxPHZ
Rachel Harding retweeted
A lay introduction to the @NeuroLibre publishing initiative conp.ca/about-neurolib… Big thank you to Patrick Bermudez, Rachel Harding (@LabScribbles), Estrid Jakobsen (@Estrid_J) and the CONP Communication Committee on putting this together!
Rachel Harding retweeted
A chemical handle that binds to but does not inhibit USP3... In principle it could serve as a starting point for future USP3-recruiting DUBTACs to rescue targets from proteasomal degradation. @thesgconline Fun collab. with @LabScribbles and Derek Wilson! bit.ly/41sxlbo
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