Structura Biotechnology @structurabio
Algorithms, Software and Systems for Cryo-EM. Makers of CryoSPARC. structura.bio Toronto, Ontario Joined May 2016-
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My grandfather built motors that powered big machines. In a lab not so different from his workshop, my colleagues and I uncovered the assembly of the bacterial motor. Today, this discovery has been published in @NatureMicrobiol #MolecularNodes #Discovery nature.com/articles/s4156…
Paper out @COSB_CRSB In collaboration with @IFSCUSP and @CryoEM_PNCC, bacterial Selenocysteine Synthase SPA-cryoEM structure was solved at high-resolution. First of several to come 💪🏻🎉
Using #CryoSPARC 3D Flexible Refinement to explore continuous heterogeneity in your #cryoEM data? Check out a new in-depth guide and video on preparing custom tetrahedral meshes that can improve 3D Flex results, plus potential pitfalls to avoid: guide.cryosparc.com/processing-dat…
Working on getting from 2D to 3D with #cryoEM data? Check out our newly updated #CryoSPARC guide page on Ab-Initio Reconstruction, with expanded algorithm descriptions, figures, and details about important parameters! guide.cryosparc.com/processing-dat…
Working on local refinement in #cryoEM? Check out our fully updated #CryoSPARC guide pages, featuring helpful theory notes, commonly adjusted parameters, a new video on mask creation methods, and updated case study processing EMPIAR-10073! guide.cryosparc.com/processing-dat…
I'm delighted to share that the peer-reviewed version of our work investigating the molecular effects of NDUFS4 knockout on mitochondrial complex I is now published in The EMBO Journal @MRC_MBU embopress.org/doi/full/10.10…
The new reference-based motion correction in @structurabio 's cryoSPARC is great! Processing for 110 kDa protein, difficult dataset to process due to the small particle with no defining features, so was hard to align. Left is before RBMC, Right is after.
Today is the second anniversary of DCI-Lausanne, and we're thrilled to share the incredible news: Our amazing team (especially Sergey and Inay), has just gifted us with the extraordinary achievement of a 1.12A ApoF structure from the Titan without an energy filter! 🚀 @DCI_EM
We are looking for a Software Engineer to join the #CryoSPARC team! Join us to work on exciting new #cryoEM software solutions: structura.bio/careers/softwa…
The 3D structure that powers our heart—myosin—finally unraveled with the help of #alphafold2 and cryo-EM with surprises nature.com/articles/s4158… nature.com/articles/s4158…
Our paper is now in @Nature: #CryoEM 6 Å reconstruction of #human cardiac thick filament C-zone in #mavacamten, showing #myosin heads, tails, #titin, #MyBP-C. Many implications for a 60-year mystery on #cardiac #muscle #physiology, #structure and #disease. shorturl.at/mwU16
We're doing it again! This time in Boston! Come join myself & some amazing #datascientists #cryoEM and #drugdiscovery folks to talk all things generative AI, protein structure and dynamics at "Structure and Drug Discovery in the Age of Data and AI" Oct 25 2023.
I have bid a fond farewell to my wonderful colleagues at the @MRC_MBU, and I'm excited to share that today I had a very warm welcome in my new adventure with the fabulous team at @structurabio!
How does the cytokine storm lead to inflammation via MAPKs? New in @ScienceMagazine our structure of the MAP2K MKK6 activating MAP #kinase p38 shows how the signal transmits by @PaulineJYX and @ErikaPellegri13 a great collaboration @gervasiolab on MD science.org/doi/10.1126/sc…
Sjors Scheres @SjorsScheres
15K Followers 660 Following Joint Head of Struct. Studies @MRC_LMB #RELION, #cryoEM, #amyloids, #OpenScience All opinions my own. Same name on https://t.co/7ZvFwboaIY and https://t.co/DCRukHhSh7
Misha Kudryashev 🔬.. @MishaKudryashev
4K Followers 971 Following Group Leader at the Max Delbruck Center for Molecular Medicine @MDC_Berlin Professor in Charité – Universitätsmedizin Berlin Science / Biophysics / Cryo-EM
Kelly Nguyen @KellyTHD_Nguyen
5K Followers 1K Following Group Leader @MRC_LMB /Structural Biologist/Biochemist. Amateur baker in free time #RNAworld #spliceosome #telomerase #telomeres #cryoEM #Xraycrystallography
Imaging_Artifact @ImagingArtifact
3K Followers 3K Following Sharing the good and the bad of electron microscopy and related ❄️🔬Ice crystal hall of fame 🧊🏆 #ElectronMicroscopy #CryoEM #TeamTomo
Basil Greber @BJ_Greber
5K Followers 1K Following Structural Biologist: #CryoEM #Transcription #DNArepair. MRC career development fellow/team leader at @ICR_London. Views my own. @[email protected]
Brady Johnston @bradyajohnston
15K Followers 2K Following structural biologist, scientific animator, creator of #MolecularNodes, he/him #rstats #b3d mstd: [email protected] bsky: @bradyajohnston.bsky.social
Liz Kellogg ❄️�.. @kellogg_liz
4K Followers 1K Following Assoc. Member @St Jude Structural Biology, Pew Biomed. Scholar 2021, Margaret Dayhoff Oakley Awardee 2023, Co-host of #ThePlungePodcast w/@mcianfro & @mimi1inh
Karolin Luger @LugerLab
9K Followers 1K Following (she/her). Chromatin and cryoEM afficionada. Still a fan of crystallography. @Nucleosomepolice on bsky. Here today, blue tomorrow. Opinions are my own.
Andreas Boland @BolandLab_GE
4K Followers 3K Following https://t.co/RfDg6e8gDU Biochemistry and Structural Biology @UNIGEnews; views are my own 🇩🇪 🇨🇭 🇬🇧 RT ≠ endorsement
EMDB - EMPIAR @EBI @EMDB_EMPIAR
6K Followers 4K Following Home of the Electron Microscopy Public Image Archive (EMPIAR) and the Electron Microscopy Data Bank (EMDB)
Ben Engel @bengeliscious
8K Followers 3K Following https://t.co/fKnd53tQsT @biozentrum Exploring cells with #CryoEM. Plants and algae in a changing climate. ❄🔬 OF 🌿 4THE 🌍! @[email protected]
Wim Hagen @WimJHH
4K Followers 588 Following Cryo-EM. Playing drums with the world-famous Janse Bagge Bend.
Ieva Drulyte @IevaDrulyte
2K Followers 1K Following Structural biologist, baker, runner | #CryoEM @thermofisher 🔬🇳🇱 | PhD @AstburyCentre 🇬🇧 | Opinions definitely my own | She/her
Ali Punjani @a_punjani
1K Followers 54 Following CEO of Structura Biotechnology Inc, makers of cryoSPARC software for single-particle cryo-EM analysis. PhD student studying ML/AI in Toronto.
Kelvin Lau always @kl.. @klausenhauser
3K Followers 3K Following 🇨🇦🇭🇰👨🔬@ protein production and structure facility 🇨🇭Equally #proteins #plants #transit #cats #politics. My views here
Lander Lab @LanderLab
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Ariane Briegel @BriegelAriane
4K Followers 1K Following Professor at the Institute of Biology, Leiden University, Co-director NeCEN @[email protected]
Nerys Thornhill @NerysThornhill
0 Followers 20 Following
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101 Followers 163 Following ディスクゴルフを時々やっています。時々ですが本気です。PDGA#50695
Woody @Woodger_Faugas
157 Followers 481 Following MS3 @UCSF via @NorthwesternU, et al.・medical knowledge, medtech, & law・he/him・opinions ⇨ my own
YCF @144491CHA
0 Followers 4 Following
Markel Martínez-Carr.. @markelmc
6 Followers 74 Following Postdoctoral Researcher - Structural Biology - interested in archaeal DNA replication
brijesh patel @brijesh6080
138 Followers 2K Following Provide Web App and App, Soft Ware solution and Dedicated developer in Reactjs, React Native, Nodejs, Python, Laravel, WP, Ofice 365. skype id : brijpatel6080
Nicholas Palmer @NicholasJPalmer
13 Followers 47 Following PhD student at UPenn in Biochemistry and Molecular Biophysics I like science, programming, and other random crap.
countrytractor @countrytractor1
5 Followers 92 Following
Lea Hoffmann @Lea_Hoff_
14 Followers 21 Following #PhDStudent @MoellerGroup #cryoEM #structuralbiology @UniOsnabrueck
陳博邦 @popangchen
1 Followers 51 Following
이인균 @iingyun738495
0 Followers 9 Following
The Postdoctoral @thepostdoctoral
20K Followers 22K Following #postdoc #postdoctoral #postgraduate #fellowship #sciencejobs #postdocjobs #scholar #grants #research #job • Tag us with #thepostdoctoral or @thepostdoctoral
Peter Horanyi @pshoranyi
177 Followers 819 Following membrane protein crystallographer and biophysicist at UCB
Goldman Lab @GoldmanLab
672 Followers 583 Following Prof Adrian Goldman’s lab @BioEnvHel @helsinkiuni @UniversityLeeds (Group Page: https://t.co/ZT8Fpz0PIS) #MembraneProtein #StructuralBiology. Tweets by lab members.
Wangweize @Wangweize367324
0 Followers 18 Following
Sourabh Kundu @Sourabh_bio
6 Followers 147 Following
Nanometria @nanometria
23 Followers 53 Following We provide cutting-edge solutions to meet your research and development challenges in microscopic data analysis.
Tom Helin @TomHelin317681
72 Followers 2K Following
Malibongwe Ntombela @okuhle354
38 Followers 297 Following
KakoRF23 @KakoRf23
2 Followers 52 Following PhD in single-particle cryoEM (nerd), Wicked Problems co-founder, and lucky
De Biasio Lab @De_Biasio_group
42 Followers 69 Following We're a lab based at @KAUST_news using Cryo-EM to study DNA replication and repair complexes.
Biao Qiu @BiaoQiu1
139 Followers 211 Following
Thara Antony @AntonyThara
123 Followers 786 Following Passionate about Molecular Biology, Epigenetics and DNA Replication Research
Mervey401 @mervey_401
2 Followers 32 Following
Jiyoon Lee @Jiyoon_molbio
4 Followers 20 Following BG Lab @ Gachon University 1st semester of master's Biomolecular Geometry 🧸e-mail: [email protected] #cryoem #smc
Micheal o מִיכָ�.. @StuartPrower
880 Followers 4K Following Health Sciences. Spanish sympathizer of the Jews. Against all Totalitarianisms. Down with identity Postmodernism. Islam out of Europe
Yuchi @Yuchi681817
5 Followers 8 Following
Magic W.W. @csuxuwang
1 Followers 81 Following
v29 @v49670
17 Followers 296 Following
ਸ਼ਬਦ* @SakshamSehgal
638 Followers 6K Following 𐨀𐨁𐨣𐨿𐨡𐨿𐨪𐨀𐨯𐨿𐨨𐨅 𐨢𐨅𐨱𐨁 𐨭𐨿𐨪𐨬𐨆 𐨦𐨃𐨱𐨡𐨿 𐨡𐨿𐨩𐨂𐨨𐨿𐨣𐨎 𐨯𐨱𐨯𐨿𐨪𐨯𐨌𐨟𐨨𐨨𐨿 𐨀𐨁𐨣𐨿𐨡𐨿𐨪 𐨟𐨌 𐨪𐨠𐨁𐨣𐨁𐨌𐨪𐨁𐨮𐨏
Alexandra Naplavova @a_naplavova
1 Followers 15 Following
Rahul Sharma @rahulbki
119 Followers 228 Following
rdk31 @rdk311
43 Followers 428 Following dancing with electrons in ice / ml / nix / https://t.co/yZYj4mco0s
Beta_unfold @BetaUnfold
20 Followers 170 Following
Kushagra Payal @memeion123
20 Followers 407 Following
shuai wu @shuaiwu864314
0 Followers 5 Following
Tanakan Paladkong @TanakanPaladko1
3 Followers 111 Following
相对自由 绝对�.. @WofeLife
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lucas DAVID @lucasDA02745560
6 Followers 66 Following
Nano Science and Tech.. @ITBreakCom
2 Followers 73 Following Fostering Innovation, Empowering Futures: NSTC - Where Science Shapes Tomorrow.
Srijita Acharya @SrijitaAcharya1
8 Followers 35 Following
trisha rice @trishar03292950
78 Followers 157 Following
Elisabetta Massone @EMassone2
151 Followers 2K Following I adore Knowledge; the Devil does nothing for free. You can check my CV and on my LinkedIn Account. Thank you.
cryoEM Papers @cryoEM_Papers
13K Followers 0 Following I'm a bot that surveys the cryoEM literature for you! Operated by @fredericpoitev1 & @CorneliusGati, adapted from PaperBots twitter app developed by @fxcoudert
Sjors Scheres @SjorsScheres
15K Followers 660 Following Joint Head of Struct. Studies @MRC_LMB #RELION, #cryoEM, #amyloids, #OpenScience All opinions my own. Same name on https://t.co/7ZvFwboaIY and https://t.co/DCRukHhSh7
Tamir Gonen 🎗️ @gonenlab
6K Followers 526 Following Professor @UCLA School of Medicine @HHMINEWS Investigator; Membrane proteins; #cryoEM; crystallography; #MicroED; #firstgen; Opinions my own. 👋👋👋🎗️
Misha Kudryashev 🔬.. @MishaKudryashev
4K Followers 971 Following Group Leader at the Max Delbruck Center for Molecular Medicine @MDC_Berlin Professor in Charité – Universitätsmedizin Berlin Science / Biophysics / Cryo-EM
ChimeraX @UCSFChimeraX
7K Followers 15 Following UCSF ChimeraX - software for visualizing biomolecules
Kelly Nguyen @KellyTHD_Nguyen
5K Followers 1K Following Group Leader @MRC_LMB /Structural Biologist/Biochemist. Amateur baker in free time #RNAworld #spliceosome #telomerase #telomeres #cryoEM #Xraycrystallography
Imaging_Artifact @ImagingArtifact
3K Followers 3K Following Sharing the good and the bad of electron microscopy and related ❄️🔬Ice crystal hall of fame 🧊🏆 #ElectronMicroscopy #CryoEM #TeamTomo
Basil Greber @BJ_Greber
5K Followers 1K Following Structural Biologist: #CryoEM #Transcription #DNArepair. MRC career development fellow/team leader at @ICR_London. Views my own. @[email protected]
Dimitry Tegunov @DTegunov
4K Followers 662 Following Mostly #cryoEM-related tweets. Group leader at a biotech company. Views expressed are strictly my own.
Liz Kellogg ❄️�.. @kellogg_liz
4K Followers 1K Following Assoc. Member @St Jude Structural Biology, Pew Biomed. Scholar 2021, Margaret Dayhoff Oakley Awardee 2023, Co-host of #ThePlungePodcast w/@mcianfro & @mimi1inh
Andreas Boland @BolandLab_GE
4K Followers 3K Following https://t.co/RfDg6e8gDU Biochemistry and Structural Biology @UNIGEnews; views are my own 🇩🇪 🇨🇭 🇬🇧 RT ≠ endorsement
EMDB - EMPIAR @EBI @EMDB_EMPIAR
6K Followers 4K Following Home of the Electron Microscopy Public Image Archive (EMPIAR) and the Electron Microscopy Data Bank (EMDB)
Ben Engel @bengeliscious
8K Followers 3K Following https://t.co/fKnd53tQsT @biozentrum Exploring cells with #CryoEM. Plants and algae in a changing climate. ❄🔬 OF 🌿 4THE 🌍! @[email protected]
Wim Hagen @WimJHH
4K Followers 588 Following Cryo-EM. Playing drums with the world-famous Janse Bagge Bend.
The Nogales Lab @NogalesLab
7K Followers 115 Following The Nogales Lab at UC Berkeley. #CryoEM #Transcription #Microtubules #ChromatinModification #Telomerase Twitter account managed by lab members.
MRC Laboratory of Mol.. @MRC_LMB
26K Followers 1K Following MRC Laboratory of Molecular Biology aims to understand biological processes at the molecular level to help tackle human health problems and disease.
Ieva Drulyte @IevaDrulyte
2K Followers 1K Following Structural biologist, baker, runner | #CryoEM @thermofisher 🔬🇳🇱 | PhD @AstburyCentre 🇬🇧 | Opinions definitely my own | She/her
Ali Punjani @a_punjani
1K Followers 54 Following CEO of Structura Biotechnology Inc, makers of cryoSPARC software for single-particle cryo-EM analysis. PhD student studying ML/AI in Toronto.
New York Structural B.. @NYSBC_Science
133 Followers 65 Following A global leader in integrated tructural biology, providing unsurpassed instrumentation, expertise, and training in X-ray crystallography, NMR, and cryoEM.
Membrane Protein PDB @MemProtPDB
1K Followers 10 Following Listing publications containing membrane protein structures. #MembraneProteins #PDB #transporter #ionchannel #GPRC #cryoEM #crystallography #NMR #cryoET
Christos Gatsogiannis @gatsogia
975 Followers 811 Following Professor@WWU_Münster, IMPB, Center for Soft Nanoscience, CryoEM of complex nanosystems
Thorsten Wagner @pixelbaumarkt
735 Followers 199 Following Project group leader @mpimoph (@intein Lab). 🐘 [email protected]
Alister Burt @AlisterBurt
2K Followers 1K Following ❄️🔬 cryo-EM @genentech views my own - love imaging and open source (especially 🐍) prev. @MRC_LMB @napari_imaging @IBS_Grenoble
Structural Biology Co.. @ActaCrystF
2K Followers 203 Following Acta Crystallographica Section F: Structural Biology Communications is a structural biology communications journal published by the @IUCr
UCSC_CryoEM @CryoemUcsc
413 Followers 559 Following Biomolecular Electron Microscopy Facility at UC Santa Cruz Structural biology Cryo-electron Microscopy More to come...
MRC MBU @MRC_MBU
3K Followers 275 Following Research at the MRC Mitochondrial Biology Unit is focussed on the involvement of mitochondria and their dysfunction in an ever-increasing range of human disease
the Peijun Zhang Lab @GroupZhang
943 Followers 29 Following We are the Zhang Lab @Oxford We use #cryoEM and #cryoET to study viruses, viral proteins, protein assemblies, and membrane proteins.
CryoVR @CryoVR
252 Followers 69 Following Virtual reality training program for #cryoEM procedures developed at Purdue University. Funded by @NIH_CommonFund. Free modules available at our website #VR
NanoSoft @NanoSoftCryoEM
433 Followers 606 Following Development and sales of innovative tools for CryoEM sample preparation
Ben Barad is now @tom.. @benjaminbarad
2K Followers 1K Following Structural Biologist • Programmer • Coffee Roaster • Assistant Professor @ OHSU • he/his/him • 🦋 @tomo.science
Agard Lab @AgardLab
848 Followers 79 Following Structural Biology/Biochemistry Lab @UCSF #cryoEM Tweets by lab members
Eddie Pryor @eddiepryor13
478 Followers 806 Following Technology Director, Cryo-EM Workflows at Thermo Fisher. Interested in Cryo-EM, Crystallography, Canines, Cycling, Cooking, and Alliteration. Views are my own.
Tim Grant @GrantCryoEMLab
1K Followers 209 Following cryo-EM structures and methods development, cisTEM development
Hannah R Bridges @HannahRBridges1
406 Followers 357 Following Biochemist and Structural Biologist|Cryo-EM Application Scientist at @structurabio|Amateur artist|All views my own|@[email protected]
Helix BioStructures @HLXBIO
488 Followers 2K Following Helix Biostructures is a structural biology CRO providing structure-based drug design services to early-stage through Fortune 500 drug discovery companies.
Proteoma @ProteomaCryoEM
290 Followers 180 Following We are both a company that specializes in cryoEM and a hub for discussion on methods and advances in the field. Follow us for tips, events, resources, and more.
Mohammad Jafari @MMJ_cryoEM
171 Followers 133 Following Senior scientist @pmcancercentre and assistant professor @UofT. Interested in cryoEM and structural biology.
David Dranow, Clone m.. @GntlmnScientist
2K Followers 499 Following he/him, Jewish, retired PhD candidate, habitual x-ray crystallographer, recovering electron microscopist, native Californian, views expressed here are my own
Daniel Asarnow @dabiophysicist
513 Followers 509 Following Postdoctoral scholar in @veeslerlab @UW I talk to students
Valentin Peretroukhin @valentinp
388 Followers 269 Following 🇨🇦🛩🤖🧬; Research Scientist @structurabio
ARC CCeMMP @CCeMMP
761 Followers 336 Following ARC Industrial Transformation Training Centre for Cryo-electron Microscopy of Membrane Proteins. Enabling tomorrow's industrial expansion in drug design.
Grigorieff Lab @GrigorieffLab
991 Followers 94 Following We strive to develop new and improved methods in electron cryo-microscopy (cryo-EM) that increase the resolution of 3D reconstructions of biological structures
DECTRIS Ltd. @DECTRIS_News
2K Followers 3K Following We make X-ray and electron detectors and love crystallography, mountains, XRD, EM, biking, PXRD, SAXS, research, CT, XRF, hiking, EXAFS, XANES & high-tech.
Joey Davis @jhdavisla.. @jhdavislab
885 Followers 277 Following Father & nerd. Working to understand the assembly, structure, and function of molecular machines using cryo-EM and mass spectrometry. MIT | Biology | Bldg. 68
AstraZenecaUK @ASTRAZENECAUK
5K Followers 363 Following Pushing the boundaries of science for patients, creating value for the UK. Not responsible for external links. Community guidelines: https://t.co/8Z69SsViVS
SoCal Cryo-EM @SoCalCryoEM
223 Followers 192 Following Connecting cryo-EM researchers across Southern California.
Linkam Scientific Ins.. @linkamstages
817 Followers 2K Following We design and manufacture temperature and environmental control devices for microscopes, spectrometers and more, for enhanced sample analysis.
Filippo Mancia @pippomancia
4K Followers 3K Following Professor @ColumbiaPS @Columbia - Membrane protein biochemist & structural biologist - Airmiles expert - #Panarea aficionado - #ManciaLab #instagram @mancialab
Elizabeth Villa @TheVillaLab
5K Followers 1K Following biophysicist @ucsdbiosciences @hhminews, cell exploration, molecular anthropology @[email protected]
Melody Campbell @MelodyGCampbell
2K Followers 747 Following Assistant professor @FredHutch studying dynamic cell surface proteins using #cryoEM | ❄️🔬🧫🎨 | she/her
Ellen Zhong @ZhongingAlong
7K Followers 902 Following Assistant Professor @PrincetonCS. #proteins247 #ml #cryoem #compbio #cryodrgn ❄️🐉#ai4science Prev: @MIT @DeepMind @DEShawResearch
Fromme Lab @Fromme_Lab
905 Followers 731 Following We study how cells sort important stuff around their insides and to their outsides | Golgi aficionados | @Cornell & @CornellMBG | Tweets by lab members
Arvinas @ArvinasInc
3K Followers 259 Following A revolutionary approach to protein degradation therapeutics. https://t.co/eppnBxVbQi
Institute for Protein.. @UWproteindesign
15K Followers 664 Following We create proteins that solve challenges in medicine, technology & sustainability // Co-developers of @Foldit // @UWMedicine | https://t.co/1PR2DtKdeB
PiperProteinProductio.. @PiperProteins
3K Followers 146 Following Scientific illustrations and animations playground for #SciVis🔎💡🎨 Mostly using #Blender3D and #cryoEM data. Views&Arts by @SarahJ_Piper. Insta: piperproteins
Wah Chiu @WahChiu1
478 Followers 80 Following CryoEM investigator and Professor at Stanford University
Harvard Cryo-EM Cente.. @HC2EM
1K Followers 2K Following Consortium formed by Harvard Medical School, Dana-Farber Cancer Institute, Boston Children’s Hospital, & Massachusetts General Hospital. @harvardmed 🟦☁️ @HC2EM
Shuimu Biosciences @ShuimuBio
94 Followers 321 Following Unveil the mystery of your target with our CryoEM platform. | The official account of Shuimu BioSciences | Please contact with 📧 [email protected]
Quantum Detectors @QDetectors
403 Followers 716 Following Cutting edge detector technology for world leading laboratories.
Jacob Lewis 🧬 📷 @Jacob_Lewis90
447 Followers 539 Following Group leader @MolHorizons @UOW studying all things DNA replication | DECRA fellow & NHMRC Investigator
BBA @BBAjournals
3K Followers 5K Following A set of journals encompassing biochemistry, biophysics, molecular biology, cell biology, genomics, bioinformatics, metabolomics, proteomics & systems biology.
Chris Horne @ChrisH_NZ
516 Followers 730 Following 🇳🇿 Kiwi structural biologist working on Kinases and Pseudokinases @WEHI_research | @WEHI_Postdocs | Up the Blackcaps 🏏
Delmic @delmicbv
796 Followers 3K Following Delmic is a passionate high-tech company that develops powerful and user-friendly solutions for light and electron microscopy.Check out our latest preprint! We use #CryoEM continuous heterogeneity analysis to model how ATP-hydrolysis triggers structural changes in an AAA+ helicase that drive DNA unwinding – a fundamental step in replication! biorxiv.org/content/10.110… #CryoEM #DNAReplication @structurabio
My grandfather built motors that powered big machines. In a lab not so different from his workshop, my colleagues and I uncovered the assembly of the bacterial motor. Today, this discovery has been published in @NatureMicrobiol #MolecularNodes #Discovery nature.com/articles/s4156…
Cryo-EM structures of adenosine receptor A3AR bound to selective agonists | Nat Commun doi.org/10.1038/s41467…
Newly published cryo-EM structures of the human bitter taste receptor TAS2R14 are shedding new light on how the human tongue can recognize more than 100 structurally diverse tastant compounds associated with bitter flavours. chemistryworld.com/news/microscop…
Did you know we were first to achieve Cryo-EM 3D reconstructions surpassing 3/4 Nyquist resolution with a direct detector? Learn more on our timeline cataloging the many big breakthroughs that make up our unique history. Visit: directelectron.com/timeline/
Mechanical activation opens a lipid-lined pore in OSCA ion channels. @Nature. Check the #cryoEM #structure of this #ionchannel in the UniTmp database: pdbtm.unitmp.org/entry/8xaj nature.com/articles/s4158…
@MiTeGen Newsletter Is Out - Features: Acta Cryst D Paper - in situ Screening & Data Collection from Microcrystals - Have You Tried Our Loops Yet? - Two Crystallography Workshops - #CryoEM Storage and Shipping System - Upcoming Events - News - Read -> zurl.co/02xG
Paper out @COSB_CRSB In collaboration with @IFSCUSP and @CryoEM_PNCC, bacterial Selenocysteine Synthase SPA-cryoEM structure was solved at high-resolution. First of several to come 💪🏻🎉
Beautiful in situ structures of the V-ATPase from @RubinsteinJohn - 10 years ago I was amazed on what #cryoEM could do for these structures - now we can see them in native environments! High resolution cryo-EM of V-ATPase in native synaptic vesicles biorxiv.org/content/10.110…
Sharing our work on developing counter-measures against porcine-deltacoronavirus (PDCoV) which is also infecting humans! Led by @RexhepajMegi @YoungjunPark11 & Lisa Perruzza w Fabio Benigni @HHMINEWS @UWBiochemistry biorxiv.org/content/10.110… 1/15
Congrats to all the participants of the 2024 @cshlcourses cryoEM course, and special congrats to Team 3: @Nancy_Jaiswal23, @Denjoi1, Edem Gavor, the winners of this year’s competition! We hope you all had a great time and share the knowledge you’ve gained with others!
Our @arc_gov_au @CCeMMP SPA workshop has come to an end - thank you all for joining!🥳 Special thanks to the expert instructors Aidan, Matt, Hamish and Sepideh!👏 #cryoEM #SPA @bluesocks81 @SValimehr @AidanGrosas
.@UniUtrecht researchers unveiled how a sugar-based receptor triggers opening of a human coronavirus spike. These #cryoEM findings enhance our understanding of mechanisms that the viruses may employ to gain entry into our cells. ➡️ ter.li/4fzdk5 bit.ly/4a1bwTE
Researchers use time-resolved #cryoEM to reveal conformational changes during G-protein activation by the β2-adrenergic receptor. This method could be used to mechanistically dissect other GPCR signaling events. @MPapasergiScott @Guille_PH ow.ly/fNWA50QVxwb
We have exciting news on NTCP! In our very recent study - now out in @NatureComms - we found out how NTCP interacts with the antiviral drug bulevirtide. Congratulations to @Hongtao_Liu2019 and the rest of the team #SLC #CryoEM Find out more here: rdcu.be/dBT8p
@DawidZyla @klausenhauser @Guillawme They should be extremely close, like to 1 resolution shell, if the same masks and phase randomization starting resolution are used (defaults are 75% the res @ 0.143 for CS and res @ FSC= 0.8 for Relion) discuss.cryosparc.com/t/different-re…
Thanks to all who attended the #BPS2024 #CryoEM subgroup, to all the superb speakers, and big thanks to @mcianfro for organizing a fantastic meeting (and a lively mixer afterwards with lots of great conversations!)
Thanks everyone for attending our 3 Day single-particle #cryoEM workshop. Huge thanks to all our teachers and helpers as well 🤩 @arc_gov_au @CCeMMP
Yesterday Blender, today we go to @cryosparc land! 🧊 Full house for Day 1 of the @CCeMMP single particle #cryoEM workshop with expert guides Matt, Brian, Sepideh and Michael (✈️ from QLD). Anyone recognise the molecule yet? 😅 @arc_gov_au @CCeMMP
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