Current Opinion/Research in Structural Biology @COSB_CRSB
Editors of Current Opinion & Current Research in Structural Biology. Opinions are our own. All aspects of molecular structure & dynamics of macromolecules journals.elsevier.com/current-opinio… Joined May 2019-
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Protein function relies on subtle structural changes. GraSp-PSN web server aids in analyzing protein structures beyond atom contacts, assessing global connectivity and perturbations. Access it here pople.mbu.iisc.ac.in and read about it here sciencedirect.com/science/articl…
Molecular dynamics simulations reveal spontaneous binding of Coagulation Factor V to phosphatidylserine-containing membranes, shedding light on conformational dynamics and lipid-protein interactions. sciencedirect.com/science/articl…
Congrats to You Min Ahn, Janesha Maddumage @JaneDazzy and @ChorizoSzeto for their beautiful work now published "The impact of SARS-CoV-2 Spike mutation on peptide presentation is HLA allomorph-specific" doi.org/10.1016/j.crst… @ElsevierConnect @COSB_CRSB
CD8+ T cells play a key role in fighting viral infections like SARS-CoV-2. Studying their response to Spike protein mutations can help understand vaccine efficacy. sciencedirect.com/science/articl…
Orange carotenoid proteins in cyanobacteria protect against excess light. They switch from an inactive orange form to an active red form in response to blue-green light. Recent studies reveal their structures and potential biotech applications. sciencedirect.com/science/articl…
Publish in CRSB special issue! Special content articles attract 20% more citations and are downloaded on ScienceDirect twice as often within the first 24 months than articles published in regular issues! sciencedirect.com/journal/curren…
Call for papers in CRSB! Special Issue on "Recent advancements of artificial intelligence in structural biology." Submit your manuscript by 9/30! sciencedirect.com/journal/curren…
I'm pleased and grateful to share that our review on Multiscale Biomolecular Simulations in the Exascale Era has just been published in Current Opinion in Structural Biology @COSB_CRSB sciencedirect.com/science/articl… [1/3]
Homorepeats are repeated segments of amino acids found in proteins across all kingdoms of life. They play vital roles in biology but are also linked to diseases. Mostly found in disordered proteins, new methods are revealing their structures and functions sciencedirect.com/science/articl…
Our review "Machine learning approaches in predicting allosteric sites" with F Nerin @ALLODD_ITN is now open access at @COSB_CRSB @elsbiomedchem sciencedirect.com/science/articl…. The full issue on "Sequences & Topology" and #allostery is now open! Read it here: sciencedirect.com/journal/curren…
Fascinating read on allostery, perhaps the most important concept in the regulation of cellular processes: All over or overall – Do we understand allostery? sciencedirect.com/science/articl…
Some proteins have tangled structures like knots, which can't be untangled easily. Such knots might help proteins perform specific tasks and resist damage. Learn more about the study of knotted proteins in COSB! sciencedirect.com/science/articl…
There are LSD1 modulators in the clinic, but although degraders & inhibitors (mostly αKG-competitve) have been developed for Jumonji demethylases, they aren’t yet being tested in patients quite yet, as summarized in this nice recent @COSB_CRSB review. Now switching gears.../8
Paper out @COSB_CRSB In collaboration with @IFSCUSP and @CryoEM_PNCC, bacterial Selenocysteine Synthase SPA-cryoEM structure was solved at high-resolution. First of several to come 💪🏻🎉
Proteins often regulate their own activity through flexible regions, which can inhibit protein or DNA binding and control complex formation. Despite being challenging to study, understanding these interactions helps uncover biological mechanisms. sciencedirect.com/science/articl…
Amyloidoses are deadly diseases caused by proteins clumping into harmful structures in the body. Technologies like NMR and cryo-EM help understand these structures, leading to targeted therapies using molecules and antibodies. sciencedirect.com/science/articl…
Intrinsically disordered proteins can take on many shapes. Studies show changes in their shape can affect how they interact with other molecules, impacting various cellular processes. Conformational entropy in molecular recognition: sciencedirect.com/science/articl…
Scientists traditionally used computational methods to study biomolecular electrostatics. Now, advanced experimental tools based on NMR enable direct measurement of electrostatic potentials around biomolecules! sciencedirect.com/science/articl…
Neurodegenerative diseases involve proteins clumping abnormally in the brain. Recent findings show these proteins can separate into liquid-like structures in cells, possibly leading to solid clumps linked to disease. sciencedirect.com/science/articl…
New COSB issue available on Folding and Binding (2024)! Edited by Dyson & Wright sciencedirect.com/science/articl…
Sam Horrell 🗿 @DrHorrell
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30 Followers 59 Following Research line focuses on the study of the light perception, photosynthesis, and photoprotection mechanisms in cyanobacteria & their potential applications ☀️🦠Gard Otnes @EnsligS
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348 Followers 457 Following Fostering Research and Innovation through Cryo-EM based Research Development at The National Research and Innovation Agency (BRIN)Jógvan Magnus Haugaa.. @foeroyingur
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32 Followers 354 FollowingAlfred Hartojo @AlfredHartojo29
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1K Followers 2K Following Revealing the hidden world of shape shifting enzymes using Cryo-EM. Senior research associate at Newcastle University, UK.Toma Ikeda @Research_toma
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1K Followers 1K Following @Stanford Postdoc • @UCBerkeley PhD Biophysics • @hdfcures fellow • Protein misfolding linked to neuro diseases • Single-molecule tools• Space/Pisco enthusiastSigrid Milles @MillesSigrid
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7K Followers 724 Following Structure is a monthly publication of @CellPressNews dedicated to research at the cutting edge of #structuralbiology. Tweets are by the Editors.Andreas Boland @BolandLab_GE
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3K Followers 2K Following A #newPI and lecturer at @ourANU | researching bacterial thiol redox pathways and virulence factors | community builder | storyteller | views my own | she/herSyma Khalid @ProfSyK
8K Followers 3K Following Prof of Computational Microbiology. Oxford Biochemistry & St Anne’s College. Bacterial Cell Envelopes. Chair of @hecbiosim. #computationalmicrobiology #LFC 🌈Pratyush Tiwary @tiwarylab
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3K Followers 807 Following X-ray wrangler | enzyme engineer | crystal wizard Building a new beamline and being stupidly excited about it! Views are my own. she/herWolf Lab @HiCryoEM
3K Followers 4K Following Cryo-EM on Okinawa! Structural Biology. Biophysics. Virology. Microbiology. OIST. Opinions are my own. 🇦🇹🇪🇺🇺🇸🇯🇵🇮🇱🇹🇼🇪🇸🇱🇰🇧🇷🇻🇪🇺🇦🇲🇽Basil Greber @BJ_Greber
5K Followers 1K Following Structural Biologist: #CryoEM #Transcription #DNArepair. MRC career development fellow/team leader at @ICR_London. Views my own. @[email protected]MRC Laboratory of Mol.. @MRC_LMB
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349 Followers 203 Following Structural biologist and protein biochemist. Interested in bacterial pathogenesis and host-microbiome interactions. Junior Group Leader at @LeibnizFMP.Karen C. Glass, PhD @KarenGlassLab
705 Followers 980 Following Associate Professor of Pharmacology, University of Vermont College of Medicine We study how the histone code is read and what the words mean. #epigeneticsReid Alderson @ReidAlderson
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366 Followers 556 Following Professor of Chemistry. Magnetic Resonance; Structural Biology, Biochemistry; Copper homeostasisRadfordLab @RadfordLab
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57K Followers 1K Following Bienvenue sur le compte officiel de l'EPFL. English account: @EPFL_enEPFL @EPFL_en
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1K Followers 733 Following Interested in cryoEM, cytoskeleton, and mechanosensation at the molecular level.Möglich Lab @MoeglichLab
383 Followers 305 Following Möglich Lab at the University of Bayreuth. https://t.co/oEx0RnRfI3Harald Janovjak @haraldjanovjak
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879 Followers 914 Following RNA Molecular Biology Laboratory - Université Libre de Bruxelles - Ribosome biogenesis, RNA processing, RNA modification, nucleolus, cancer, ribosomopathyBergeron Lab @BergeronLab
1K Followers 779 Following Structural biology, and beer. Not necessarily in that order. Based at King's College London.🇬🇧 🇪🇺 🇫🇷 🇯🇴 🇷🇺 🏴 🏴 🇲🇽 🇨🇳Matthew Solomonson @mattsolomonson
452 Followers 326 Following Associate Director, Genomic Data Visualization @ The Broad Institute of MIT and HarvardMatouschek Lab @TheMALab
264 Followers 122 Following Research group using cellular, molecular, biochemical, and structural biology to understand the ubiquitin proteasome system.Journal of Molecular .. @JMolBiol
5K Followers 3K Following Journal of Molecular Biology is run by scientists for scientists. Here to share exciting new research and news. Opinions of scientific editors.Hideaki E. Kato @emeKato
5K Followers 998 Following Professor at UTokyo. (postdoc @Stanford) / b.1986 / structural biology, protein engineering, rhodopsin, GPCR https://t.co/6mkl7Vi4qNCongratulations to @jinan_wang and our collaborators for first paper in @COSB_CRSB! GaMD simulations captured multiple times of spontaneous and highly accurate RNA binding to protein. Mechanism of RNA recognition by a Musashi RNA-binding protein sciencedirect.com/science/articl…
“Protein” no longer means what it used to sciencedirect.com/science/articl… happy to share our new opinion article in collaboration with MS Fornasari, @NPalopoli , Peter Tompa and Silvio Tosatto. @COSB_CRSB
Beautiful - the pump that keep giving!
I am glad to finally share our review on the impact of 2'-O-ribose methylation on various types of RNAs. @COSB_CRSB authors.elsevier.com/c/1bJJ2,LqArFv…
@SoBuelow look what just arrived- with your great image on the front cover. I shall send you a copy in the post. @COSB_CRSB. I’m biased of course, but this is a tidy volume of review articles on macro molecular assemblies- sciencedirect.com/journal/curren…
It was a good week in the Glass lab! MSPS student Saleh Alkrimi received an ACPHS Blythe scholarship, two PharmD students were recognized with faculty choice awards, and our recent work on the BRFP1 bromodomain was accepted in Current Research in Structural Biology @COSB_CRSB.
Structural biology will be key in the #COVID19 pandemic, said Professor Sir Tom Blundell, EiC of Current Research in Structural Biology. Listen to the full interview here: bit.ly/2UUOeJL @COSB_CRSB
We are proud to introduce our new Co-Editor-in-Chief of Current Opinion in Structural Biology: Ruth Nussinov. Ruth is a Professor at the School of Medicine, Tel Aviv University, & Senior Principal Investigator at the National Cancer Institute: bit.ly/2prNnVa @CO_CRSTBI
We’re super excited to share results we had been aiming for since the foundation of the lab! Multimodule NRPS structures! science.sciencemag.org/content/366/64…
Great TEDx talk by Nico Thomä on how protacs work as "molecular glue." A model for explaining science in accessible terms.
Thanks to @TEDxBasel and @LabThoma. Still blown away by how a small molecule can make two proteins stick #molecularglues. Beautiful work also by labs Ebert, @fischerlab1, Handa, Chopra & Chamberlain, @jaybradner, @kaelin_lab! m.youtube.com/watch?v=AsJzeL…
Congratulations to Wolfgang Baumeister of @MPI_Biochem, recipient of the Ivano Bertini Award 2019 @instructhub #IBSBC2019. Wolfgang has contributed so much to structural biology, and has 61 entries @PDBeurope. Find them all here: bit.ly/2V70fOm