Structure @Structure_CP
Structure is a monthly publication of @CellPressNews dedicated to research at the cutting edge of #structuralbiology. Tweets are by the Editors. cell.com/structure/home Cambridge, MA, USA Joined August 2012-
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Online now! Structural and functional characterization of itaconyl-CoA hydratase and citramalyl-CoA lyase involved in itaconate metabolism of Pseudomonas aeruginosa dlvr.it/T63wpj
Online now! Structural and functional insights into yeast Tbf1 as an atypical telomeric repeat-binding factor dlvr.it/T63hTV
Online now! Constitutive activity of ionotropic glutamate receptors via hydrophobic substitutions in the ligand-binding domain dlvr.it/T63KTF
In our new #cryoFIB #cryoET preprint we imaged actin filaments in very fast moving Plasmodium falciparum sporozoites. We shed some light on the mechanism of gliding motility and find unexpectedly long and large actin bundles in the cytoplasm and nucleus! biorxiv.org/cgi/content/sh…
Happy to share FID-Net-2 to transform complex #NMR data👇 Using dedicated pulse sequences FID-Net-2 generates high-quality quantitative aromatic 13C-1H maps and accurate uncertainties for the transform. biorxiv.org/content/10.110… @gogulan_k @bhu_vaibhav @TheCrick @UCLLifeSciences
Years after the idea and preliminary experiments, Claire Coupland's amazing structure of the endogenous vacuolar- or vesicular-ATPase in its native vesicle is now in bioRxiv "High resolution cryo-EM of V-ATPase in native synaptic vesicles" biorxiv.org/content/10.110…
New publication on the structure and allosteric regulation of Alzheimer’s target SHIP1 from @Dr_WillB, @Ogileadi, @ARUK_ODDI, @KavliOxford. Including an @XChem_DLS fragment screen with 91 structures. authors.elsevier.com/sd/article/S09…
Online now! OPUS-Rota5: A highly accurate protein side-chain modeling method with 3D-Unet and RotaFormer dlvr.it/T5vTZv
Team headed by @Dr_WillB & Opher Gileadi @CMD_Oxford @ARUK_ODDI determined the apo, and magnesium and phosphate-bound structures of the phosphatase and C2 domains of SHIP1. They also reported 91 fragment bound structures of SHIP1. cell.com/structure/full…
Happy #EarthDay2024 ! Have you considered how your research impacts the Earth? Check out this collection in @MolecularCell for some examples of labs trying to help reduce the negative impact and trying to have a positive impact - cell.com/molecular-cell…
📣 Register now – the @HorizonsMolBio conference will take place @mpi_nat from Sep 9 to 12. It connects scientists from different fields & gives insights into #MolecularBiology. Organized by students @ IMPRS for Molecular Biology @uniGoettingen. horizons.uni-goettingen.de/registration/i…
📣 Register now – the @HorizonsMolBio conference will take place @mpi_nat from Sep 9 to 12. It connects scientists from different fields & gives insights into #MolecularBiology. Organized by students @ IMPRS for Molecular Biology @uniGoettingen. horizons.uni-goettingen.de/registration/i…
Team headed by Cheng-Cai Zhang investigated the dynamic interactions of two modules from a nonribosomal peptide synthase by X-ray crystallography and activity assays. A conserved "RGXR" motif mediates these interactions cell.com/structure/full…
Team headed by Anthony Kossiakoff @UChicago solved the cryo-EM structure of the TonB-dependent transporter PhuR. The structure reveals the presence of an extracellular bound heme and molecular basis for heme recognition and uptake cell.com/structure/full…
Team headed by Quan Chen & Haiyan Liu at the University of Science and Technology of China, Hefei used a neural network-based model to design proteins containing a cavity with the shape of a small molecule and solved two crystal structures. cell.com/structure/full…
New #ModelAngelo software builds atomic models quickly and accurately, and is able to identify previously unknown proteins from #cryoEM maps. Read more about the programme, developed by @jamaliki1998, @LMB_PhD student in @SjorsScheres group: www2.mrc-lmb.cam.ac.uk/modelangelo-so… #LMBResearch
Take a look at our new preprint on the molecular architecture of synaptic vesicles purified from mouse brains and in neurons grown on grids biorxiv.org/content/10.110… 🧵👇
Team headed by @alastairstewart & their collaborators determined cryo-EM structures of the rotor-less F1-ATPase, which reveal a series of conformational states during the ATP hydrolysis cycle @VictorChangInst cell.com/structure/full…
Antoniya Aleksandrova, Edoardo Sarti & @LucyRForrest describe EncoMPASS, a database for relating integral membrane proteins of known structure based on sequence, structure and symmetry in their new Structure paper cell.com/structure/full…
Online now! Mapping structural and dynamic divergence across the MBOAT family dlvr.it/T5dP1z
Many congratulations to @WilliamWuZhiyi and his work on KDEL trafficking now online in @Structure_CP - sciencedirect.com/science/articl… In collaboration with Kathryn Smith, Andreas Gerondopoulos, Tomoaki Sobajima, Joanne L. Parker, Francis Barr and @inwardopen.
Sjors Scheres @SjorsScheres
15K Followers 658 Following Joint Head of Struct. Studies @MRC_LMB #RELION, #cryoEM, #amyloids, #OpenScience All opinions my own. Same name on https://t.co/7ZvFwboaIY and https://t.co/DCRukHhSh7Protein Data Bank @PDBeurope
22K Followers 872 Following PDBe is a founding member of the wwPDB. The PDBe team is also responsible for the PDBe-KB, AlphaFold DB and 3D Beacons resources.rcsb pdb 💉🧬💻.. @buildmodels
14K Followers 473 Following RCSB PDB promotes a structural view of biology. Funded by @NSF, @thenci, @NIAIDNews, @NIGMS, @NIH, & @doescience. Contact [email protected] with service questions.Sergey Ovchinnikov �.. @sokrypton
12K Followers 3K Following Scientist, Assistant Professor @MITBiology, #FirstGen, ProteinBERTologistStructura Biotechnolo.. @structurabio
5K Followers 449 Following Algorithms, Software and Systems for Cryo-EM. Makers of CryoSPARC.Sam Horrell 🗿 @DrHorrell
5K Followers 5K Following Structural Biology Facility Manager @ImperialCollege. Expect protein crystallography🧬💎🎇, Boardgames♟️, D&D🎲, MTG🧙, and birds called Nori and Kili 🦜🦜とりさん @biochem_fan
6K Followers 4K Following とりさん。学問(≠研究)を楽しむ程度の能力。 生合成経路・天然物化学・酵素反応機構・構造生物学・プログラミングが好き。言語や古典文学にも手を出したり。ただの下手の横好き。 科学におけるオープンソース・オープンデータ原理主義者。 言うまでもなく、全ては個人の意見・感想です。 注意:持病のため気分の波あり。鬱発言多しMRC Laboratory of Mol.. @MRC_LMB
26K Followers 1K Following MRC Laboratory of Molecular Biology aims to understand biological processes at the molecular level to help tackle human health problems and disease.JCIM & JCTC Journals @JCIM_JCTC
9K Followers 975 Following Tweets from Journal of Chemical Information and Modeling (JCIM) and Journal of Chemical Theory and Computation (JCTC) from @ACSPublicationsSyma Khalid @ProfSyK
8K Followers 3K Following Prof of Computational Microbiology. Oxford Biochemistry & St Anne’s College. Bacterial Cell Envelopes. Chair of @hecbiosim. #computationalmicrobiology #LFC 🌈Misha Kudryashev 🔬.. @MishaKudryashev
4K Followers 971 Following Group Leader at the Max Delbruck Center for Molecular Medicine @MDC_Berlin Professor in Charité – Universitätsmedizin Berlin Science / Biophysics / Cryo-EMEMDB - EMPIAR @EBI @EMDB_EMPIAR
6K Followers 4K Following Home of the Electron Microscopy Public Image Archive (EMPIAR) and the Electron Microscopy Data Bank (EMDB)Cynthia Wolberger @CWolberger
6K Followers 278 Following Professor and Director, Biophysics and Biophysical Chemistry @BiophysJHMed @HopkinsMedicine, structural biologist, fan of the active voice. I post preprints.Max Planck Institute .. @MPIbp
5K Followers 441 Following Our research concerns biological membranes with particular emphasis on the structure and function of membrane proteins. #Biophysics #cryoEM #structuralbiologyRhys Grinter @Rhys__G
2K Followers 1K Following Lab Head in the Department of Microbiology at Monash University studying the structural basis of bacterial disease.Liz Kellogg ❄️�.. @kellogg_liz
4K Followers 1K Following Assoc. Member @St Jude Structural Biology, Pew Biomed. Scholar 2021, Margaret Dayhoff Oakley Awardee 2023, Co-host of #ThePlungePodcast w/@mcianfro & @mimi1inhAndreas Boland @BolandLab_GE
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67K Followers 979 Following The European Molecular Biology Laboratory drives visionary basic research and technology development in the life sciences. https://t.co/7IVx6E26AOAnastassis Perrakis @TassosPerrakis
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583 Followers 555 Following Molecular biology and biophysics to understand ion channel function and evolution. Views expressed here are mine, not necessarily my colleagues'.Kuldeep Jangid @kuldeep_jangid9
28 Followers 430 Following Structural and computational biologist. PhD scholar @IIT Roorkee #X- ray Crystallography #Cryo-EM #Molecular Biology #Drug discoveryjoghie_ertanto @critical_room
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14 Followers 53 Following Neuroscience PhD student in the Jayaraman Lab at UTHealth HoustonMichael Epp @Michael_A_Epp
12 Followers 389 Following Research technician in the Li lab at the Stowers Institute for Medical Researchうさぎ @usagi_pharm_62
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1 Followers 64 FollowingFreeRadical @0FreeRadical0
318 Followers 613 Following Working to create a better future. Fan of rational thinking. It's ok to change your mind when presented with new info. Science, facts, and cats.Amer A Hossain @amer_hossai1
297 Followers 753 Following Postdoc in the @J_Maciejowski Lab @MSKCancerCenter | PhD from @MarraffiniLab @RockefellerUniv studying DNA repair proteins in bacteria-phage conflictsJake Hill @JakeAHilll
17 Followers 88 Following PhD student at Bradford/Leeds | X-ray Crystallography and protein dynamicsElisabetta Massone @EMassone2
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28 Followers 114 Following Cells and tissues interact with and respond to their physical environment's shape, which they can also modify through growth, remodeling, or active forces.VachaLab @LabVacha
749 Followers 117 Following Biological membranes, proteins and their interactions. @CEITEC_BrnoJack Zhang Lab @zhang_lab
1K Followers 732 Following Jack (Kai) Zhang Lab at Yale University Intracellular Transport, Cell Motility, Mitochondria, Cryo-EM/ET Methodology -- Cellular Structures, Life & HealthPhung Cheng Fei @salmon_shitake
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95 Followers 420 FollowingCAELUS UBILIBET Stat. @didactist
584 Followers 5K Following Hyperdidactist. Philologist; Obstinated-Criticist. Support Ecology-Economy of Minds PhD ENGINEER {semantic,graphic}memory IN SCIENCE We Trust. #TheoryWaveHey Gang @HeyGang6901
16 Followers 140 FollowingRahul Mehta @RM_SGMCB_CryoEM
291 Followers 2K Following Member of Max Planck Research Group @Małopolskie center of biotechnology, laboratory of Dr. Sebastian Glatt, overly fond of RNAs Structural biology, cryo-EMAndrew X Ye @Andrew_XYe
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69 Followers 1K Following Computational Biophysical Chemistry PhD student @UArkansas 🔎 Ribosomes. Learning to be in “NOW”. Heal my NS. Neurodivergent. Mental Heath Advocate. Teacher.🐢Emmanuel Afriyie @eafriyie5
5 Followers 14 FollowingQuentin Smith @Q_M_Smith
276 Followers 335 Following PhD student interested in #CRISPR-Cas systems. Currently @MRC_LMS (@RuedaLab). Tweets are my own.songxin @songxin230223
15 Followers 114 FollowingSandi Sufiandi, Ph.D. @sandisufiandi
346 Followers 422 Following Physical Biochemistry Researcher and Coordinator of Cryo EM based Research Development at The National Research and Innovation Agency - BRINJ. @qq_cc_j
29 Followers 695 FollowingRobert Dilley @RobertLDilley
322 Followers 1K Following Oncology fellow @DanaFarber, postdoc in Walter lab @HMS_BCMP, studying macromolecular maintenance and cancer, husband of @Leela_Chakra, he/himSjors Scheres @SjorsScheres
15K Followers 658 Following Joint Head of Struct. Studies @MRC_LMB #RELION, #cryoEM, #amyloids, #OpenScience All opinions my own. Same name on https://t.co/7ZvFwboaIY and https://t.co/DCRukHhSh7Protein Data Bank @PDBeurope
22K Followers 872 Following PDBe is a founding member of the wwPDB. The PDBe team is also responsible for the PDBe-KB, AlphaFold DB and 3D Beacons resources.rcsb pdb 💉🧬💻.. @buildmodels
14K Followers 473 Following RCSB PDB promotes a structural view of biology. Funded by @NSF, @thenci, @NIAIDNews, @NIGMS, @NIH, & @doescience. Contact [email protected] with service questions.Kresten Lindorff-Lars.. @LindorffLarsen
13K Followers 2K Following Protein and coffee lover, father of two, professor of biophysics and sudo scientist at the #LinderstrømLang Centre for Protein Science 🇩🇰 Same usr @ 🦋Structura Biotechnolo.. @structurabio
5K Followers 449 Following Algorithms, Software and Systems for Cryo-EM. Makers of CryoSPARC.Tamir Gonen 🎗️ @gonenlab
6K Followers 528 Following Professor @UCLA School of Medicine @HHMINEWS Investigator; Membrane proteins; #cryoEM; crystallography; #MicroED; #firstgen; Opinions my own. 👋👋👋🎗️MRC Laboratory of Mol.. @MRC_LMB
26K Followers 1K Following MRC Laboratory of Molecular Biology aims to understand biological processes at the molecular level to help tackle human health problems and disease.Tristan Croll @CrollTristan
4K Followers 479 Following Principal Scientist at Altos Labs. Making data-based macromolecular modelling faster, more accurate and a bit more fun. Devoted husband and father.Syma Khalid @ProfSyK
8K Followers 3K Following Prof of Computational Microbiology. Oxford Biochemistry & St Anne’s College. Bacterial Cell Envelopes. Chair of @hecbiosim. #computationalmicrobiology #LFC 🌈Misha Kudryashev 🔬.. @MishaKudryashev
4K Followers 971 Following Group Leader at the Max Delbruck Center for Molecular Medicine @MDC_Berlin Professor in Charité – Universitätsmedizin Berlin Science / Biophysics / Cryo-EMEMDB - EMPIAR @EBI @EMDB_EMPIAR
6K Followers 4K Following Home of the Electron Microscopy Public Image Archive (EMPIAR) and the Electron Microscopy Data Bank (EMDB)The Nogales Lab @NogalesLab
7K Followers 115 Following The Nogales Lab at UC Berkeley. #CryoEM #Transcription #Microtubules #ChromatinModification #Telomerase Twitter account managed by lab members.Prof. Hao Wu @WuLabHarvard
5K Followers 172 Following Asa and Patricia Springer Professor of Structural Biology @ Harvard Medical School and Boston Children’s Hospital. #immunology #structure_biologyCynthia Wolberger @CWolberger
6K Followers 278 Following Professor and Director, Biophysics and Biophysical Chemistry @BiophysJHMed @HopkinsMedicine, structural biologist, fan of the active voice. I post preprints.Max Planck Institute .. @MPIbp
5K Followers 441 Following Our research concerns biological membranes with particular emphasis on the structure and function of membrane proteins. #Biophysics #cryoEM #structuralbiologyKarolin Luger @LugerLab
9K Followers 1K Following (she/her). Chromatin and cryoEM afficionada. Still a fan of crystallography. @Nucleosomepolice on bsky. Here today, blue tomorrow. Opinions are my own.Lander Lab @LanderLab
6K Followers 397 Following Electron Microscopy Socialism | Dept. of Structural & Computational Bio, Scripps ResearchDavid Dranow, Clone m.. @GntlmnScientist
2K Followers 499 Following he/him, Jewish, retired PhD candidate, habitual x-ray crystallographer, recovering electron microscopist, native Californian, views expressed here are my ownJosie Ferreira @J0Ferreira
480 Followers 347 Following #NewPI Exploring unusual parasite structures with cryoET | @wellcometrust Career Development fellow @ismb_london @UCL | Previously @HFSP fellow @CssbHamburgSophie Zinn-Justin @szinn3
96 Followers 79 Following Co-head of the structural biology team #I2BC_INTGEN at #I2BC Paris-Saclay #CEA Paris-Saclay, I am fond of protein structures, e-biking, diving, exploringStructural Biology-Ch.. @DBSC_IP
786 Followers 293 Following The department of Structural Biology and Chemistry at Institut PasteurChris Waudby @chris_waudby
2K Followers 1K Following Lecturer in Biomolecular NMR @school_pharmacy. Pianist, opera lover, swimmer and cyclist with an inadvertent interest in religion and science. He/him 🏳️🌈Sarah Piper @SarahJ_Piper
2K Followers 1K Following Postdoctoral Researcher @MIPS_DDB @MonashUni in Melbourne. Interested in #cryoEM ❄🔬 #SciVis🔎💡🎨 Views and Arts are my own. Founder of @PiperProteins She/herKausik Chattopadhyay @KausikChatt
1K Followers 811 Following Professor @DBS_IISERM, @IISERMohali. (We study structure-function mechanism of pore-forming proteins). Editorial Board Member @JBacteriology @ASMicrobiologyHelen Walden @hw1o9
3K Followers 3K Following Scientist, mother, feminist, drinker. Views most emphatically mine. She/HerEngin Özkan @Enozkan1
337 Followers 732 Following @UChicagoBMB. Likes molecular structures, cells, circuits and everything in between. Dislikes stepping on LEGO pieces.Alex J. Vecchio @Vecchiology
726 Followers 1K Following Asst Prof/PI @Jacobs_Med_UB • Structural biology of tight junctions & other small membrane protein-comprised assemblies • #BillsMafia #letsgobuffaloPhill Stansfeld @pstansfeld
2K Followers 2K Following Professor of Computational Biochemistry. School of Life Sciences & Department of Chemistry, University of Warwick. @memprotmd. @pstansfeld.bsky.socialRandy Read @RandyJRead
470 Followers 82 Following Interested in methods for structural biology, particularly likelihood-based. Contributor to Phenix and CCP4. Also found as @[email protected].Andrea Thorn @ThornLab
2K Followers 438 Following Scientist.🥼🧪💻Warriorsage 🦠 Viruses. Anthropogenic accidents. Macrofungi. AI methods in #StructuralBiology #CryoEM #crystallography @harbor_unihh - she/herPhil Biggin 🇪🇺 @philbiggin
2K Followers 420 Following Computational biochemist, interested in neuronal signalling at the atomic level and computer-aided drug design. All views my own. @[email protected]Rommie Amaro @RommieAmaro
8K Followers 1K Following Professor @UCSanDiego. Computational chemist & biophysicist, multiscale modeler. Viruses. Cancer. Unapologetically molecular.Theoretical & Computa.. @CompBioPhys
4K Followers 249 Following news and views from the research groups of H. Grubmüller, B. de Groot and A. Godec @mpi_nat Göttingen, Germany, Imprint: https://t.co/LsGpAHa8MPiScience journal @iScience_CP
9K Followers 2K Following iScience is the interdisciplinary journal from Cell Press publishing across life, physical, earth and health sciences.Scott C Blanchard @TheBlanchardLab
2K Followers 1K Following Member, Endowed Chair; Department of Structural Biology, St. Jude Children's Research Hospital @StjudeResearch @StJudeStructBio @TheBlanchardLabKozo Tomita Lab: RNA .. @RnaLaboratory
301 Followers 131 Following Department of Computational Biology and Medical Sciences, Graduate School of Frontier Sciences, The University of Tokyo Kashiwa, Chiba 277-0882, JapanNils Walter Lab @NilsWalterLab
2K Followers 223 Following We study cool RNAs - reaching unprecedented single molecule sensitivity with fancy microscopes and answering the question of how cellular life worksIISc Bangalore @iiscbangalore
176K Followers 73 Following The official Twitter account of the Indian Institute of Science (IISc)ChristiansonLaborator.. @ChristiansonLab
2K Followers 494 Following Biological chemist and protein crystallographer; professor and former department chair @PennChemistry; Chesapeake Bay sailor, homeport Annapolis, Maryland.Jay Brito Querido @Jayquerido
862 Followers 758 Following Assistant Professor at the @UMichMedSchool and Research Assistant Professor at the @UMLifeSciencesJack Zhang Lab @zhang_lab
1K Followers 732 Following Jack (Kai) Zhang Lab at Yale University Intracellular Transport, Cell Motility, Mitochondria, Cryo-EM/ET Methodology -- Cellular Structures, Life & HealthDeepti Jain @deepjxtal
974 Followers 580 Following Structural Biologist, Associate Professor, Transcription Regulation, Flagella, Biofilm, PseudomonasVachaLab @LabVacha
749 Followers 117 Following Biological membranes, proteins and their interactions. @CEITEC_BrnoTHE DUMENIL LAB @DumenilLab
677 Followers 344 Following Whatever it takes to discover exciting new mechanisms of host pathogen interactionsIOCB Prague @IOCBPrague
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1K Followers 911 Following Assistant Professor @yourUMG @uniGoettingen, Group Leader @mpi_nat ; Structural biology of gene expression. https://t.co/9fwC20BvzUÖzkan Yildiz @Oezkan_YildizZ
141 Followers 294 FollowingSvetlana Dodonova @Sveta_Dodonova
1K Followers 287 Following Group Leader at EMBL Heidelberg. Cryo-EM fan ❄️❄️❄️ Opinions are my ownTanjaMittag @TanjaMittag
3K Followers 667 Following Member, Department of Structural Biology, St. Jude Children's Research Hospital @StJudeResearch @StJudeStructBio. Opinions my ownIDPseminars @IDPseminars
3K Followers 119 Following Virtual seminar series focusing on intrinsically disordered proteins. Seminars every month. Run by @alexholehouse and @proteinmagnusRadfordLab @RadfordLab
2K Followers 182 Following Radford/Brockwell and associated groups, based in the @AstburyCentre. Studying protein folding and the effects of force. Tweets are by members of the lab group.Kamel Elomari @ElOmariKamel
36 Followers 48 Following Senior Beamline Scientist at Diamond Light Source Lecturer in Biochemistry at Somerville CollegeDepartment of Biochem.. @BiochemOxford
3K Followers 267 Following Twitter stream for the Department of Biochemistry, @UniofOxfordYeates Lab @Yeates_Lab
195 Followers 13 Following Lab twitter account for the Todd Yeates group @UCLARoger Castells @rcastellsg
1K Followers 2K Following Biotechnologist - Postdoc @UCLA @Yeates_Lab // PhD @JohnInnesCentre & BSc @UABBarcelona / SciEd @whatifnet // #cryoEM #proteindesign #ai #dlMembrane Protein PDB @MemProtPDB
1K Followers 10 Following Listing publications containing membrane protein structures. #MembraneProteins #PDB #transporter #ionchannel #GPRC #cryoEM #crystallography #NMR #cryoETGur Lab @itugurlab
435 Followers 47 Following GUR Biomolecular Engineering Laboratory. Specializes in #ComputationalModeling #PeptideInhibitors #MotorProteins #Transporters #ProteinEngineeringEdward T Eng @edward_eng
2K Followers 622 Following a scientist and manager at the New York Structural Biology Center, SEMC & NCCAT - https://t.co/4F3rtLp5TT - Views are my own, RT/Likes do not imply endorsement.Hummer Lab @HummerLab
2K Followers 94 Following Molecular simulations and computational biophysics @MPIbpMagnetic Resonance Ne.. @nmr900
6K Followers 52 Following Curating Magnetic Resonance news since 2011, no endorsements, use #NMRchat New MR Chat ! Upcoming Magnetic Resonance Events in 2024 ✈️🧲 https://t.co/nfZnYf1HDqFrank Sobott @FrankSobott
2K Followers 1K Following Mass speccie in Leeds (Astbury, FBS, the lot) Chemist using Physics to study Biology. European. Well travelled, for work and fun.Siewert-Jan Marrink @CG_Martini
2K Followers 0 Following Martini lover. Shaken, stirred or self-assembled.STAR Protocols @STARProtocols
6K Followers 202 Following STAR Protocols offers open access peer-reviewed protocols that are structured, transparent, accessible & reproducible. Lead Editor Jeremy Petravicz @JeremyNeuroAksimentievLab @aksimentievLab
1K Followers 86 Following We explore fascinating phenomena at the interface of physics, biology, and nanotechnology at the University of Illinois.Aravind Penmatsa @PenmatsaLab
1K Followers 104 Following Associate Professor at the Molecular Biophysics Unit, IIScMargot Riggi @MargotRiggi
573 Followers 365 Following Molecular animator, molecular biologist and biochemistIn our new #cryoFIB #cryoET preprint we imaged actin filaments in very fast moving Plasmodium falciparum sporozoites. We shed some light on the mechanism of gliding motility and find unexpectedly long and large actin bundles in the cytoplasm and nucleus! biorxiv.org/cgi/content/sh…
Happy to share FID-Net-2 to transform complex #NMR data👇 Using dedicated pulse sequences FID-Net-2 generates high-quality quantitative aromatic 13C-1H maps and accurate uncertainties for the transform. biorxiv.org/content/10.110… @gogulan_k @bhu_vaibhav @TheCrick @UCLLifeSciences
Years after the idea and preliminary experiments, Claire Coupland's amazing structure of the endogenous vacuolar- or vesicular-ATPase in its native vesicle is now in bioRxiv "High resolution cryo-EM of V-ATPase in native synaptic vesicles" biorxiv.org/content/10.110…
New publication on the structure and allosteric regulation of Alzheimer’s target SHIP1 from @Dr_WillB, @Ogileadi, @ARUK_ODDI, @KavliOxford. Including an @XChem_DLS fragment screen with 91 structures. authors.elsevier.com/sd/article/S09…
Happy #EarthDay2024 ! Have you considered how your research impacts the Earth? Check out this collection in @MolecularCell for some examples of labs trying to help reduce the negative impact and trying to have a positive impact - cell.com/molecular-cell…
📣 Register now – the @HorizonsMolBio conference will take place @mpi_nat from Sep 9 to 12. It connects scientists from different fields & gives insights into #MolecularBiology. Organized by students @ IMPRS for Molecular Biology @uniGoettingen. horizons.uni-goettingen.de/registration/i…
We are happy to announce that this year's Horizons in Molecular Biology will be held in Göttingen from September 9th to 12th. Register for Horizons 2024 now through: survey.academiccloud.de/index.php/4775…. #Horizons2024 #MolecularBiology #ScienceConference
New #ModelAngelo software builds atomic models quickly and accurately, and is able to identify previously unknown proteins from #cryoEM maps. Read more about the programme, developed by @jamaliki1998, @LMB_PhD student in @SjorsScheres group: www2.mrc-lmb.cam.ac.uk/modelangelo-so… #LMBResearch
Take a look at our new preprint on the molecular architecture of synaptic vesicles purified from mouse brains and in neurons grown on grids biorxiv.org/content/10.110… 🧵👇
Many congratulations to @WilliamWuZhiyi and his work on KDEL trafficking now online in @Structure_CP - sciencedirect.com/science/articl… In collaboration with Kathryn Smith, Andreas Gerondopoulos, Tomoaki Sobajima, Joanne L. Parker, Francis Barr and @inwardopen.
Our first all-atom structural dynamics of MUCINS effort is live at @biorxivpreprint biorxiv.org/content/10.110… Please give it a read & send feedback! 🤓 #glycotime #compchem
📢WHAT DO WE WANT?! MUCINS! WHEN DO WE WANT'EM?! NOW! YOU ASKED FOR IT!! @mia_rosenfeld @RommieAmaro and I have a new preprint out documenting our all-atom modeling and simulation of respiratory MUCINS!!! Please read and give constructive feedback!! biorxiv.org/content/10.110…
📩Abstract submission is open for the "2nd BioExcel Conference on Advances in Biomolecular Simulations" 🗓️ 20 - 23 October 2024 📍Brno, Czech Republic ℹ️ Information and submission ➡️ bit.ly/3TBqidQ Some great speakers lined up❗️ ⭐️Registration opens 15 April 2024
Ready to apply to our Postdoctoral Fellowships 2024 call? Get all the steps right! 1️⃣Learn about funding basics 2️⃣Check your eligibility 3️⃣Hunt host organisations 4️⃣Draft your application 5️⃣Get feedback from experts 6️⃣Submit your application! More info: europa.eu/!dB783t
When I joined David Barford's group @MRC_LMB it was with the goal of using my cryo-ET and computational skills to help them understand funky biology. I joined @TDendooven and @StanislauY's efforts to average the native gamma tubulin ring complex (γTuRC) from tomograms of SPBs
A new study @ScienceMagazine by @valeroche @marechal_nils @LynnZechiedrich + al. on 1 of the coolest molecules - #DNA gyrase - provides structural support to a 45 yrs old sign inversion model of DNA🧬 supercoiling regulation also published @ScienceMagazine
We are happy to share our research published. Substrate specificity of Mycobacterium tuberculosis tRNA terminal nucleotidyltransferase toxin MenT3 academic.oup.com/nar/article/do…
The new @EMDB_EMPIAR cryo-electron tomography (cryo-ET) browser allows you to see proteins up close in the cellular environment. Over 1,800 high-resolution reconstructed tomograms from cryo-plasma-FIB milled Chlamydomonas reinhardtii cells are available. ebi.ac.uk/about/news/ann…
Nanodomains confining FUS and nanodomains confining RNA have distinct properties, but RNA nanodomains observed here should not be consisted of RNA since there’s only 50 pM RNA in 10 uM FUS. Therefore, it’s likely that two types of nanodomains are formed by two distinct levels of…
We are very excited to share the structure of the T. brucei MCC and a putative activation mechanism! Out now in structure: cell.com/structure/full…
Register today for this free @SynBioBeta event: synbiobeta.zoom.us/webinar/regist…
Are you coming to the 2024 Dutch Peptide Symposium, May 31 at VU Amsterdam O2 auditorium? We have some exciting invited speakers confirmed, and now we need you! Registration is open until 20 May, abstracts until 1 May, all on dutchpeptidesymposium.com