Doudna Lab @doudna_lab
News from Jennifer Doudna's lab at @UCBerkeley @igisci. Tweets from lab members and not Jennifer Doudna unless signed JD. Tweets represent personal views only. doudna.berkeley.edu Berkeley, CA Joined December 2015-
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The future of genome editing is in vivo! Check out our latest @PNASNews perspective from @doudna_lab. Had a lot of fun discussions with @kevin_wasko and @JRo_Hamilton about the past, present, and future of in vivo delivery. pnas.org/doi/10.1073/pn…
How genome editing can be more efficacious and accessible in the future. Delivery of editors without virus vectors. pnas.org/doi/10.1073/pn… @PNASNews @doudna_lab @connortsuchida @UCBerkeley
The Hachiman defense system functions through sensing genome integrity. Beautiful structure function study by the @doudna_lab. Congrats @owen_t_tuck @ben_a_adler et al! biorxiv.org/content/10.110…
A beautiful story by two terrific scientists!! Finally Hachiman has a mechanism!!
A beautiful story by two terrific scientists!! Finally Hachiman has a mechanism!!
Congrats Owen and Ben on this great work!
Mechanism of the Hachiman immune system finally deciphered A beautiful study from the Doudna lab shows that Hachiman is a genome integrity sensor biorxiv.org/content/10.110… Congrats @doudna_lab and colleagues!
Hachiman is hot off the (preprint) presses! @owen_t_tuck and I in @doudna_lab present a model for how this broad-activity defense system recognizes genome integrity, a core feature of phage infection. Check out the preprint and Owen's thread for the news:
Hachiman is hot off the (preprint) presses! @owen_t_tuck and I in @doudna_lab present a model for how this broad-activity defense system recognizes genome integrity, a core feature of phage infection. Check out the preprint and Owen's thread for the news:
New preprint on phage defense from the lab co-led by @owen_t_tuck and @ben_a_adler - check it out!
New preprint on phage defense from the lab co-led by @owen_t_tuck and @ben_a_adler - check it out!
The first paper of this year, “Engineering self-deliverable ribonucleoproteins for genome editing in the brain”, is officially out @NatureComms. This is the first project of my postdoc @doudna_lab, where we focused on delivery method development for CRISPR genome editors in the…
Very happy to share my first postdoc paper! We predicted the structures of 67,715 viral proteins to study their evolution and function. In addition to lots of cool findings, I hope this structural resource is helpful to the community! biorxiv.org/content/10.110…
In vivo human T cell engineering with enveloped delivery vehicles go.nature.com/47vW1Rp
The @DanaherCorp @igisci @berkeleyMCB Beacon for CRISPR Cures aims to solve an "unsolvable" challenge: how to develop such cures for "rare" diseases that, at present, have low to zero commercial value. statnews.com/2024/01/09/dou… As @Jasonmmast @statnews explains, doing so will…
Only in the @UofCalifornia system can we leverage clinical expertise @UCSF w/ CRISPR editing @UCBerkeley & cell manufacture @UCLA to partner with @DanaherCorp to advance therapies for patients with rare diseases @doudna_lab @UrnovFyodor @Kohn_Lab @igisci ucsf.edu/news/2024/01/4…
Grateful to be part of this team of "superheroes" partnering with @DanaherCorp to bring CRISPR to bear on the space of rare diseases, starting with Artemis-deficient SCID and HLH, and eventually other inborn errors of immunity! Where would the Avengers be without SHIELD?
Grateful to be part of this team of "superheroes" partnering with @DanaherCorp to bring CRISPR to bear on the space of rare diseases, starting with Artemis-deficient SCID and HLH, and eventually other inborn errors of immunity! Where would the Avengers be without SHIELD?
IGI is teaming up with @DanaherCorp to focus on creating treatments for two rare immune disorders! We hope to scale this work into a #CRISPR platform in which a new medicine for any genetic disease can be rapidly developed. Learn more: ow.ly/aElX50Qp2qn #RareDisease
Excited to lead the Artemis-SCID project team for the new @igisci @DanaherCorp collaboration to advance CRISPR therapies for rare diseases @UCSFChildrens! @doudna_lab @UrnovFyodor @Kohn_Lab @UCSF @UCSFPediatrics Here's the non-paywall IGI press release
Excited to lead the Artemis-SCID project team for the new @igisci @DanaherCorp collaboration to advance CRISPR therapies for rare diseases @UCSFChildrens! @doudna_lab @UrnovFyodor @Kohn_Lab @UCSF @UCSFPediatrics Here's the non-paywall IGI press release
Frances Arnold @francesarnold
66K Followers 779 Following Innovation by evolution, Linus Pauling Professor at Caltech, Nobel Prize in Chemistry (I am an engineer of the biological world)
David R. Liu @davidrliu
64K Followers 59 Following Professor at Harvard, Broad Institute, & HHMI. Our lab integrates chemistry & evolution to illuminate biology & enable new therapeutics. IG/Threads: @davidrliu1
Nature Biotechnology @NatureBiotech
302K Followers 2K Following Publishing the very best of biotech science and business. Part of @SpringerNature and @NaturePortfolio. On Facebook (natbiotechnol) & IG (nature.biotechnology)
Patrick Hsu @pdhsu
30K Followers 3K Following co-founder @ArcInstitute, @BerkeleyBioE professor | researcher & investor in genome editing, biotech, AI | 🇨🇦 @harvard @broadinstitute @editasmed, Fast Grants
Arjun Raj @arjunrajlab
25K Followers 2K Following Just another LLM. Tweets do not necessarily reflect the views of people in my lab or even my own views last week. https://t.co/fZAnUCqd12
Molecular Cell @MolecularCell
125K Followers 582 Following Molecular Cell is a Cell Press journal that aims to publish the best papers in molecular biology.
Fyodor Urnov @UrnovFyodor
15K Followers 533 Following Gene editor + Professor of Molecular Therapeutics @berkeleyMCB + Director of @igisci @danahercorp Beacon for CRISPR Cures.
Niko McCarty 🧫 @NikoMcCarty
23K Followers 861 Following Writing and editing stories about scientific progress, especially in biology. Founding Editor @AsimovPress Head of Creative @AsimovBio
Dan Nomura @DanNomura
17K Followers 9K Following Professor of Chemical Biology and Molecular Therapeutics at UC Berkeley; Departments of Chemistry and Molecular and Cell Biology
Nicole M. Gaudelli @NicoleGaudelli
5K Followers 269 Following EIR @GVteam, dreamer, inventor of ABE. Interested in genomic medicine and next-generation application of gene editing tools. Leonardo’s & Isabella’s Mom.
Karolin Luger @LugerLab
9K Followers 1K Following (she/her). Chromatin and cryoEM afficionada. Still a fan of crystallography. @Nucleosomepolice on bsky. Here today, blue tomorrow. Opinions are my own.
Mo Khalil @MoKhalilLab
8K Followers 2K Following Prof. @ Boston University and Wyss Institute. Understanding the natural world by building a synthetic one. website: https://t.co/PyjGQRHoUy
Innovative Genomics I.. @igisci
16K Followers 940 Following Using genome engineering to solve humanity’s greatest problems in health, climate & sustainable agriculture. Partnership between @UCBerkeley and @UCSF. #CRISPR
Jason Sheltzer @JSheltzer
17K Followers 2K Following Assistant prof at @YaleMed. Interested in aneuploidy, mitotic kinases, drug targeting, CRISPR, and promoting diversity in science. Co-founder @MelioraTx.
Jay Bradner, M.D. @jaybradner
22K Followers 938 Following Physician-scientist making medicines with friends, memories with family. EVP R&D and CSO at Amgen
Rockefeller Universit.. @RockefellerUniv
20K Followers 1K Following The Rockefeller University is a world-renowned center for research and graduate education in the biomedical sciences, chemistry, bioinformatics and physics.
James Olzmann @OlzmannLab
10K Followers 7K Following Associate Professor @UCBerkeley & Investigator @czbiohub. Lipid droplets, ferroptosis, ubiquitin, chembio, molecular therapeutics. Diversity, equity, inclusion.
Leslie Vosshall PhD @leslievosshall
24K Followers 918 Following VP/CSO @HHMInews & Head of #VosshallLab @rockefelleruniv Toward Excellent, Diverse, Equitable, Inclusive, & Open Science MASTODON: @[email protected]
Omar Abudayyeh @omarabudayyeh
7K Followers 2K Following McGovern Fellow @mcgovernmit by way of @broadinstitute | @harvardmed |@MIT Molecular tool lab. Co-founder @Sherlock_bio & https://t.co/GnLoSlRvsZ & https://t.co/ElMMNGf8bL
Michael C. Jewett @MichaelCJewett
7K Followers 483 Following Professor of Bioengineering, Stanford University
snipe @realeasymonies
9 Followers 77 Following
Juliana Smetana @SmetanaJu
0 Followers 4 Following
JUST FOR FUN 😎 @FunnyBlogger_
177 Followers 2K Following
Jorge @Jorge197152
2 Followers 2K Following 🇪🇺🇵🇹☃️🇨🇭⛏️⛑️ #ForeignAffairsAnalyst #Geopolitics Comparison between Developing and Developed Countries. @UN @NASA @USGS @AirForceTimes
Yee Kwan Law @YeeKwanLaw2
124 Followers 536 Following 1st year PhD Student at MUW/@gsf_lab (CeMM). Biochemistry graduate from Univ (Oxford). Interested in structural and chemical biology of transporters, immunology
Gina Boubion @GinaBoubion
797 Followers 794 Following Director of Careers @columbiajourn @columbiajournMA. Former newspaper reporter. East LA-born, NYer forever.
r alan @RRalan49
31 Followers 299 Following
Anwchai @anwchai
243 Followers 2K Following
prashant gole @prashantgole25
21 Followers 388 Following
Guyon Virginie @v_guyon
32 Followers 152 Following
metavalent stigmergy @metavalent
449 Followers 4K Following The process by which novel insights, intuitions, understandings, ideas, or concepts originate, germinate, blossom, propagate, and instantiate DCNs and DCNRs.
Yasmim @wxyasmimz
0 Followers 53 Following
Andrija Ekmedzic @Korolev2015
344 Followers 1K Following PhD in aeronautics, former Airbus employee, now his own boss, FA level 1 football coach
Andrea Manrique Rinc�.. @i_treg
125 Followers 289 Following Scientist in love with T cells, working with cancer immunotherapy. Biologist from @UdeA, PhD from @Unicamp, Postdoc at @sangerinstitute and @Cambridge_Uni
Nirai Goivndasamy @niraigovi
120 Followers 565 Following Science, technology and innovation enthusiast | Working towards bringing cultured meat to market 🐟🥩🍔
Shalini Yadav @shalini_yadav_
217 Followers 121 Following Postdoctoral Researcher at Max-Planck-Institut für Kohlenforschung
Lriv @Lriv44970703
244 Followers 2K Following
Isabella Murray @ig_murray
2 Followers 20 Following UC Berkeley undergraduate, MCB and Microbial Biology '26.
Purelite Art @PureliteArt
2K Followers 4K Following Owen is a photographer and artist specialising in creating stunning and unique images with over 40 years of experience as a photographer and artist.
hhgghjio @djjcjsjskzkz
1 Followers 19 Following
Okoye Hyginus Ekenedi.. @ekeneokoye26
712 Followers 8K Following QAQC and Technical Service Chemist 🧪 Field: Oil and Gas, Energy, Quality Assurance, Business Innovation, Oilfield Chemistry ⚗️🧪
Thomas Lab @DThomasLab
225 Followers 246 Following We study the role and regulation of NADPH oxidases in immunity - https://t.co/NGi4HtxMNN
Laudonia Lidia Dipalo @L_Lidia_Dipalo
0 Followers 44 Following
Hermine Mohr @Hermine_Mohr
107 Followers 177 Following Scientist, Neuroendocrine Cancer, Virology, Project management, Mother
Anagha Krishnan @anaghakrishnana
37 Followers 114 Following PhD Candidate @UniofOxford @theNCI @NIHOxCam Founder, Science Unlocked @PeteyGreeneProg Fulbright, Goldwater scholar math models of the immune system & cancer
Kush Coshic 🇮🇳 @KushCoshic
77 Followers 244 Following Postdoctoral Fellow at Max Planck Institute of Biophysics
Nancy Riffle @nriff
38 Followers 157 Following
Vaishnavi Mukkawar @VaishnaviMukka1
78 Followers 326 Following Senior Research Fellow at NIPGR😃🌾 Former PhD Student at Durham University, UK 🇬🇧 Studying stress tolerance mechanism in rice You can also call me ‘Navi’ ☺️
Aung Naing @AungNai47641843
27 Followers 171 Following
Constantine Tarabanis.. @DrCardioCon
171 Followers 800 Following Future chief resident @NYULangone. AI-ECG research 🫀 MD @HarvardMed, BA @Harvard. Opinions my own.
lenatschki @lenatschki
48 Followers 305 Following
khomaini hasan @lesanrego
362 Followers 639 Following Protein Engineering Scientist, Masaryk University Alumnae, Roadbiker, IUBMB, Bandung-Chapter, member of MABBI,and Faculty of Medicine, Unjani, Indonesia
shah @AsbaqAbbas
2 Followers 23 Following
Bruno @Bruno3584312677
15 Followers 81 Following
Kele_Lab (Chem. Biol... @ChemBiolHun
197 Followers 198 Following
Thiwanka Jayasiri (TJ.. @ThiwankaCJayasi
212 Followers 2K Following Re-design the way we compute @AntiumS
Innovative Genomics I.. @igisci
16K Followers 940 Following Using genome engineering to solve humanity’s greatest problems in health, climate & sustainable agriculture. Partnership between @UCBerkeley and @UCSF. #CRISPR
Feng Zhang @zhangf
50K Followers 42 Following Researcher at Broad Institute and McGovern Institute at MIT.
Jacob Corn @jcornlab
5K Followers 508 Following Genome editing, functional genomics, and cells figuring out how to eat themselves without dying. Professor of Genome Biology at ETH Zürich.
Martin Jinek @MartinJinek
4K Followers 344 Following Biochemist, structural biologist, CRISPR enthusiast
Esha @ArshadEsha99665
50 Followers 144 Following
Petr Skopintsev @PetrSkopintsev
66 Followers 105 Following
Zehan Zhou @ZehanZhou
99 Followers 591 Following PhD student @doudna_lab. Interested in all things RNA!
The Banfield Lab @BanfieldLab
9K Followers 444 Following Located at the University of California-Berkeley. Purveyors of Microbial Ecology, Bioinformatics, & Nanogeoscience. RT≠endorsements.
Jill Banfield @BanfieldJill
8K Followers 3 Following Prof Microbial Metagenomics, UC Berkeley, Member of National Academy of Science, Royal Society, and the Australian Academy of Science
ron boger @ronboger
727 Followers 997 Following phd student @doudna_lab @UCB_Biophysics, interested in computation and biology. previously google x, system 1 bio, johns hopkins
Benjamin L. Oakes @BenjaminLOakes
864 Followers 582 Following CEO, Co-Founder @scribetx | at the interface of molecular and genetic engineering to treat disease with #CRISPR
Erin Doherty @Ee_Doherty
900 Followers 988 Following Postdoc @Doudna_Lab || @UCDChem Beal lab alum RNA Chemical Biology || she/her CIRM Postdoctoral Fellow || Former NIH F31 & NIH T32
Linda T. Vo @T_lindavo
1K Followers 842 Following 🧬🧫 Biotech creation @ThirdRockV | Former PI @igisci | @nsf PhD @harvardmed @G_Q_Daley | @damonrunyon Postdoc @atUCSF @kickassscience1
Rubin Lab @therubinlab
551 Followers 99 Following News from the Rubin Lab 🧬🧫 We conduct DNA-level editing of microbial communities for understanding and control. Managed by lab members. @igisci @UCBerkeley
Honglue Shi @honglue1
259 Followers 327 Following @JCChildsFund Fellow in @doudna_lab @igisci @UCBerkeley | PhD in the Al-Hashimi lab @DukeU | genome editing | DNA and RNA dynamics | biophysics | he/him
Demis Hassabis @demishassabis
357K Followers 125 Following Co-founder & CEO @GoogleDeepMind - working on AGI. Trying to understand the fundamental nature of reality. Also revolutionising drug discovery @IsomorphicLabs
Jason Nomburg @nomburg
244 Followers 292 Following Postdoc in @Doudna_lab. PhD @VirologyHarvard in the DeCaprio and Meyerson labs. I study viruses using bioinformatics.
Katalin Kariko @kkariko
70K Followers 263 Following I am a scientist, working on the therapeutic use of in vitro transcribed mRNA.
Megan Hochstrasser @thecrispress
2K Followers 2K Following Director of Publishing @ArcadiaScience Prior: #SciComm @igisci, PhD @doudna_lab she/her @meganhoch.bsky.social on BlueSky
Kai Chen @kaichen_1990
1K Followers 390 Following Protein engineering, gene editing, synthetic chemistry/biology. PhD (09/15-05/20) with @francesarnold, postdoc (07/20-now) @doudna_lab.
Brittney Thornton @BW_Thornton
174 Followers 145 Following PhD Candidate at @UCBerkeley in @SavageCatsOnly 🐱, @Doudna_Lab 🧬, @BerkeleyMCB 🐻
Christine He @christine_y_he
674 Followers 808 Following Genomic applications @nanopore 🧬 | bioinformatics, metagenomics, microbiomes 🦠 | previously postdoc @ucberkeley, PhD @georgiatech
Jun-Jie Gogo Liu @GogoLiu
517 Followers 234 Following Associate Professor @Tsinghua_Uni focusing on RNA-Biology and Gene-Editing Tech Development || Joint-postdoc @doudna_lab & @Nogaleslab
Laura Hofman @lauraxhofman
222 Followers 202 Following Research scholar UC Berkeley @doudna_lab | previously @prinsesmaximac | @ONE Youth Ambassador
Abdullah Syed @abdullah_m_syed
287 Followers 273 Following NSERC postdoc @doudna_lab @GladstoneInst working on gene editing and SARS-CoV-2| PHD @TheChanLab
Ben Adler @ben_a_adler
2K Followers 1K Following Postdoc @ Doudna Lab - UC-Berkeley | Bacteriophage engineering | CRISPR | Biotechnology | Microbiology | All Combinations Thereof | He/him. Opinions my own.
Matthew Kan, MD, PhD @matthewjkan
2K Followers 1K Following Pediatrician-scientist & genome editor • Assistant Adjunct Professor of Pediatric Allergy/Immunology @UCSF • @Doudna_Lab and Puck Lab • @PSDP_AMSPDC Fellow
Mohammad Saffari Doos.. @MSDoost
36 Followers 32 Following
em @emileedle_
318 Followers 499 Following PhD candidate in the Cleves Lab @ Carnegie/JHU CMDB studying coral symbiosis 🪸 | Former: UCB IGI CRIPSR-Cas, Roche Seq. Diagnostics | PADI DM 🌊 | (she/her)
Ryan Allen @ryanallen1_
76 Followers 55 Following medical student @mayoclinic, @ucberkeley alum, co-founder @zone7health
Peter Hyungjun Yoon @PeterHYoon
109 Followers 239 Following
Dylan Smock @Dylan_Smock
274 Followers 544 Following UCLA MBIDP. Graduate student at @Kohn_Lab. Biochemistry & Microbiology. Passionate about RNA, microbes & greater diversity in science!!🧪🧬
Cindy Sandoval Espino.. @CindySE27
167 Followers 192 Following Bertozzi lab grad student| Stanford Biochem 👩🏽🔬🌲🤍❤️| Doudna Lab Technician 👩🏽🔬| Cal c/o 2019 👩🏽🎓🐻💙💛
Ross Wilson @RossWilsonLab
890 Followers 162 Following CRISPR whisperer in perpetual training. We're working to enable safe & accessible delivery of genome editing therapeutics. @igisci @UCBerkeley https://t.co/89o53zRYUa
Brady Cress @bradyfcress
1K Followers 2K Following Principal Investigator @igisci @UCBerkeley | Microbiome Editing | Postdoc @Doudna_lab | PhD @RPI Chemical & Biological Engineering | Hiring!
Josh Cofsky @JoshCofsky
268 Followers 56 Following Postdoc in the Kruse lab, @HMS_BCMP previously @doudna_lab / Kuriyan lab grad student in @berkeleyMCB
Tina Liu @tinaliu_phd
648 Followers 537 Following Assistant Prof of Molecular Bio & Biochem @RutgersCABM | Exploring & Engineering CRISPR-Cas systems | Former @doudna_lab postdoc | PhD @RapoportLab
Chunyu Zhao @zhaocy_1
140 Followers 133 Following Bioinformatics Scientist Lab of Katie Pollard @czbiohub @GladstoneInst ❤️👩💻🧬🥊
Elizabeth Applegate @lil_lizgate
83 Followers 130 Following Research assistant in the @doudna_lab at @igisci 🧬🔬 @UCBerkeley grad 🐻 Premed 🩺
Haridha Shivram @H_Shivram
356 Followers 325 Following Bioinformatics Scientist @Genentech Postdoc @doudna_lab @igisci. PhD @UTAustin - Host-pathogen interactions and Genomics. Views are my own.
Connor Tsuchida @connortsuchida
945 Followers 710 Following Something new | @ForbesUnder30 ‘24 | BioE PhD @doudna_lab @UCBerkeley, @UCSF, & @IGIsci ‘23 | Via @UW @Pfizer @NYUlangone @WyssInstitute
AbbyLabby @AbbyLabby_
485 Followers 461 Following Therapeutic Editing @ Lilly. Former postdoc @ Doudna Lab & trained @ Pitt #bioE #regenmed #immuno. Science nerd, podcasts, music &🐱Tweets are personal views
Gavin Knott @gavinjknott
1K Followers 793 Following RNA Biochemist | Nucleic Acid Sensors | CRISPR | Lab Head @MonashBDI | Postdoc @doudna_lab | Ph.D. UWA. Views my own.
Audrey Lapinaite @Sarkele1
1K Followers 1K Following Asst. Prof. @ ASU Interested in: snoRNAs, RNA modifications, RNA-protein interactions, CRISPR biology Trying out Mastodon: @[email protected]
Patrick Pausch @patrick_pausch
1K Followers 752 Following Group Leader @VU_LT LSC-@EMBL - CRISPR, Gene Editing and Microbiology
Enrique Lin Shiao @enrique_lins
3K Followers 741 Following Principal #Venture #Investments @CF_Foundation #Scientist #Postdoc🧑🏻🔬@doudna_lab🧬#geneediting🎙@caminosciencia #podcast #sisepuede 🇨🇷🇹🇼🇺🇸
Jennifer R Hamilton @JRo_Hamilton
2K Followers 1K Following CRISPR + gene therapy delivery 👩🔬 NIGMS K99 @doudna_lab & women in enterprising science fellow @igisciThe future of genome editing is in vivo! Check out our latest @PNASNews perspective from @doudna_lab. Had a lot of fun discussions with @kevin_wasko and @JRo_Hamilton about the past, present, and future of in vivo delivery. pnas.org/doi/10.1073/pn…
How genome editing can be more efficacious and accessible in the future. Delivery of editors without virus vectors. pnas.org/doi/10.1073/pn… @PNASNews @doudna_lab @connortsuchida @UCBerkeley
The Hachiman defense system functions through sensing genome integrity. Beautiful structure function study by the @doudna_lab. Congrats @owen_t_tuck @ben_a_adler et al! biorxiv.org/content/10.110…
A beautiful story by two terrific scientists!! Finally Hachiman has a mechanism!!
New preprint! @ben_a_adler and I @doudna_lab, in collaboration with @Emy_nim and @JoePogliano, unveil a mechanism for Hachiman immunity. The punchline - Hachiman is a genome integrity sensor. @UCB_Chemistry @igisci @HHMINEWS biorxiv.org/content/10.110… 🧵 1/14
Congrats Owen and Ben on this great work!
New preprint! @ben_a_adler and I @doudna_lab, in collaboration with @Emy_nim and @JoePogliano, unveil a mechanism for Hachiman immunity. The punchline - Hachiman is a genome integrity sensor. @UCB_Chemistry @igisci @HHMINEWS biorxiv.org/content/10.110… 🧵 1/14
Mechanism of the Hachiman immune system finally deciphered A beautiful study from the Doudna lab shows that Hachiman is a genome integrity sensor biorxiv.org/content/10.110… Congrats @doudna_lab and colleagues!
Hachiman is hot off the (preprint) presses! @owen_t_tuck and I in @doudna_lab present a model for how this broad-activity defense system recognizes genome integrity, a core feature of phage infection. Check out the preprint and Owen's thread for the news:
New preprint! @ben_a_adler and I @doudna_lab, in collaboration with @Emy_nim and @JoePogliano, unveil a mechanism for Hachiman immunity. The punchline - Hachiman is a genome integrity sensor. @UCB_Chemistry @igisci @HHMINEWS biorxiv.org/content/10.110… 🧵 1/14
New preprint! @ben_a_adler and I @doudna_lab, in collaboration with @Emy_nim and @JoePogliano, unveil a mechanism for Hachiman immunity. The punchline - Hachiman is a genome integrity sensor. @UCB_Chemistry @igisci @HHMINEWS biorxiv.org/content/10.110… 🧵 1/14
The first paper of this year, “Engineering self-deliverable ribonucleoproteins for genome editing in the brain”, is officially out @NatureComms. This is the first project of my postdoc @doudna_lab, where we focused on delivery method development for CRISPR genome editors in the…
Very happy to share my first postdoc paper! We predicted the structures of 67,715 viral proteins to study their evolution and function. In addition to lots of cool findings, I hope this structural resource is helpful to the community! biorxiv.org/content/10.110…
In vivo human T cell engineering with enveloped delivery vehicles go.nature.com/47vW1Rp
The @DanaherCorp @igisci @berkeleyMCB Beacon for CRISPR Cures aims to solve an "unsolvable" challenge: how to develop such cures for "rare" diseases that, at present, have low to zero commercial value. statnews.com/2024/01/09/dou… As @Jasonmmast @statnews explains, doing so will…
Only in the @UofCalifornia system can we leverage clinical expertise @UCSF w/ CRISPR editing @UCBerkeley & cell manufacture @UCLA to partner with @DanaherCorp to advance therapies for patients with rare diseases @doudna_lab @UrnovFyodor @Kohn_Lab @igisci ucsf.edu/news/2024/01/4…
Grateful to be part of this team of "superheroes" partnering with @DanaherCorp to bring CRISPR to bear on the space of rare diseases, starting with Artemis-deficient SCID and HLH, and eventually other inborn errors of immunity! Where would the Avengers be without SHIELD?
What does an "Avengers Unite!" team to build CRISPR Cures look like? As @leilei_wuu @endpts explains ... endpts.com/jennifer-doudn… ... this requires 1- editing experts @igisci @berkeleyMCB: @doudna_lab @giannikopoulosp and yours truly. 2- world-leading clinicians with deep…
The fantastic folks involved in this work include @doudna_lab, @UrnovFyodor, @matthewjkan, @giannikopoulosp, @Kohn_Lab @UCLAstemcell, @UCSFChildrens, @UCSF, @UCSFPediatrics
IGI is teaming up with @DanaherCorp to focus on creating treatments for two rare immune disorders! We hope to scale this work into a #CRISPR platform in which a new medicine for any genetic disease can be rapidly developed. Learn more: ow.ly/aElX50Qp2qn #RareDisease
Excited to lead the Artemis-SCID project team for the new @igisci @DanaherCorp collaboration to advance CRISPR therapies for rare diseases @UCSFChildrens! @doudna_lab @UrnovFyodor @Kohn_Lab @UCSF @UCSFPediatrics Here's the non-paywall IGI press release
IGI is teaming up with @DanaherCorp to focus on creating treatments for two rare immune disorders! We hope to scale this work into a #CRISPR platform in which a new medicine for any genetic disease can be rapidly developed. Learn more: ow.ly/aElX50Qp2qn #RareDisease
What does an "Avengers Unite!" team to build CRISPR Cures look like? As @leilei_wuu @endpts explains ... endpts.com/jennifer-doudn… ... this requires 1- editing experts @igisci @berkeleyMCB: @doudna_lab @giannikopoulosp and yours truly. 2- world-leading clinicians with deep…
Congratulations on the approval of the first CRISPR based therapy! So many patients are going to benefit thanks to this technology and the work done to develop it! @doudna_lab @VertexPharma
I am excited and a bit overwhelmed with emotion at the news of the approval of CASGEVY in the UK. Going from the lab to an approved #CRISPR therapy in just 11 years is a truly remarkable achievement. (1/3)
Today I am excited to share our preprint “Rapid DNA unwinding accelerates genome editing by engineered CRISPR-Cas9” from @doudna_lab, with co-authors @kaichen_1990, Kasia Soczek, @owen_t_tuck, @Ee_Doherty, @BW_Thornton, Bryant Xu, and Marena Trinidad. biorxiv.org/content/10.110… 1/7
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