It has taken a lot of work and a long journey, at the end we show that there is a colloidal way amino acids stabilize proteins. A great collaboration with Alfredo Alexander-Katz that proposes new theory on colloidal stability. Just published in @Naturerdcu.be/eFrqm
How do chromatin remodelers use #IDRs to find their TF binding partners? Check out San’s tweetorial about SWI/SNF (cBAF) subunit ARID1A and β-catenin, now online at Mol Cell
How do chromatin remodelers use #IDRs to find their TF binding partners? Check out San’s tweetorial about SWI/SNF (cBAF) subunit ARID1A and β-catenin, now online at Mol Cell
My lab has postdoc openings in the following areas: 1) Structural biology and single molecule biophysics; 2) Developing novel genome editing methods; and 3) Protein and RNA engineering. Please share the info with your trainees, and RT please. 🙏
postdocs.yale.edu/yale-postdocto…
🚨🚨Please RT! 📢📢
Still time to submit short talk abstract for EdinPBS2025!
Five themes this year:
· Mechanobiology
· Protein pattern formation
· 4D Genome
· Stochastic biology
· Biohydrodynamics
bit.ly/EdinPBS2025
📢New paper alert!! With @boothbylab@alexholehouse@fried_lab we take a look at how an entire proteome survives desiccation. TLDR: Desiccation tolerance is encoded in specific residues on the protein surface, and occurs primarily in biosynthetic enzymes. shorturl.at/U5VS1
Super excited to share our latest work looking at mechanisms that contribute to local hexatic and nematic ordering in tissue monolayers!
Intercellular friction and motility drive orientational order in cell monolayers | PNAS pnas.org/doi/10.1073/pn…
Excited about the to-the-point and insightful perspective on our coarse-grained DNA-protein modelling and classification work by @petr_sulc in @BiophysJdoi.org/10.1016/j.bpj.…
We are excited to announce our new manuscript is on bioRxiv edin.ac/3z7hhBH. We use super-resolution imaging, molecular biology and polymer simulations to show that nuclear RNA forms an interconnected network of microgels. Well done everyone!
Obituary: Roeland Nolte 1944-2024. I wrote this with Bert Meijer about our dear friend. Quoting Hávamál (Viking text): I know one thing which never dies: the reputation of each man. Roeland´s good reputation will certainly live forever. @NatureNano see:
rdcu.be/dDcT0
Want to model protein-mediated DNA compaction/condensation at a coarse-grained level and classify the resulting complexes? Check out our latest preprint with Laura Filion's lab @UniUtrechy and @WV_Lab@EdinburghUni! A summary (1/n) biorxiv.org/content/10.110…
Super excited about our latest preprint where we show that HIV integrase (IN) can compact the viral DNA genome. Great collaboration with @WV_Lab, @DeFeyterGroup, @zegerdebyser, and Laura Filion. A summary 🧵 (1/n)
doi.org/10.1101/2024.0…
3K Followers 4K FollowingEmpowering scientists with tools that reveal crucial insights not available before, at the molecular and cellular level | Dynamic single-molecule & Cell avidity
541 Followers 548 FollowingGroup Leader at the VIB – KU Leuven Center for Cancer Biology @vib_ccb and @Onco_KULeuven interested in tumour evolution, single-molecule multi-omics, and AI
445 Followers 2K FollowingEnjoying life one molecule at a time / Postdoc @UWproteindesign / ex @Stanford / PhD @LMU_Muenchen / tweeting in English, thinking in Bavarian, coding in Python
468 Followers 276 FollowingAgnes Noy research account: Senior Lecturer at the University of York. DNA, biophysics, modelling, supercoiling, and much more. Active in @agnesnoy.bsky.social
94 Followers 279 FollowingScience/Arts/Life, Neuroscience PhD student @bcm_neurosci | *My views do not reflect those of my institution* | 24岁清纯男「前」大学生 头很大
2K Followers 4K FollowingSingle molecule biophysicist, Tenure track assist. prof. at the University of Groningen. Enjoys food, bouldering, silliness & science. @biophysk.bsky.social
244 Followers 383 FollowingBeckman fellow ,UIUC . DPhil., University of Oxford. Computational Biophysics. I make 🧬 and 🧬 like objects move on a computer.
2K Followers 2K Following@RoyalSociety University Research Fellow @EdinburghUni @PhysAstroEd. @ERC_Research StG on Topologically Active #DNA Materials. Always learning 🧬
3K Followers 2K FollowingAt Fusion Conferences, we believe that bringing like-minded professionals, academics, and researchers together is an opportunity to make a real impact.
3K Followers 4K FollowingEmpowering scientists with tools that reveal crucial insights not available before, at the molecular and cellular level | Dynamic single-molecule & Cell avidity
2K Followers 1K FollowingPhysicist, biologist, all-round scientist. The views I express on twitter are mine alone and not those of my employer. Find me on @sciorama.bsky.social
681 Followers 956 FollowingComputational Biophysicist - Interested in Mechanobiology and Hybrid QM/MM methods - Associate Professor at the Department of Physics at Auburn University
709 Followers 543 FollowingAssociate Professor, Baylor College of Medicine, Rice Bioengineering. Chromatin, transcription, cancer epigenetics, and therapeutics.
226 Followers 457 FollowingBusiness Development Executive @edininnovations @compfluids @edinburghuni. @SOFI_CDT alumnus. Love yoga and dance. Newbie gardener. Views my own.
2K Followers 481 FollowingResearch lab @MRC_HGU, @EdinburghUni. We study DNA and chromatin structure to understand gene regulation and genome stability. Tweets by @chromatinlab members!
244 Followers 383 FollowingBeckman fellow ,UIUC . DPhil., University of Oxford. Computational Biophysics. I make 🧬 and 🧬 like objects move on a computer.
94 Followers 279 FollowingScience/Arts/Life, Neuroscience PhD student @bcm_neurosci | *My views do not reflect those of my institution* | 24岁清纯男「前」大学生 头很大
541 Followers 548 FollowingGroup Leader at the VIB – KU Leuven Center for Cancer Biology @vib_ccb and @Onco_KULeuven interested in tumour evolution, single-molecule multi-omics, and AI
2K Followers 255 Following#Chromatin biologist/biophysicist at @NIG_idenken @SokendaiU in Japan. My career and work https://t.co/Q0x6DVCOvW
Chromatin is very dynamic and flexible, NOT regular!!!
468 Followers 276 FollowingAgnes Noy research account: Senior Lecturer at the University of York. DNA, biophysics, modelling, supercoiling, and much more. Active in @agnesnoy.bsky.social
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