Wireframe Ventures @WireframeVC
We specialize in helping extraordinary seed-stage founders on a mission to improve the health of people and planet wireframevc.com San Francisco, CA Joined September 2016-
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Raising $150M wasn’t the only headline. Discovery is nothing without delivery ENV-294, our lead drug for #atopicdermatitis, has entered Phase 1b. A completely new way of tackling this disease, and potentially others across #inflammation, is playing out in patients. Experience…
Celebrating another incredible milestone for @wireframe family co @lifeschemistry. Using AI to find new cures from nature & power a diverse pipeline of high value assets entering the clinic.
Celebrating another incredible milestone for @wireframe family co @lifeschemistry. Using AI to find new cures from nature & power a diverse pipeline of high value assets entering the clinic.
Exciting milestone for Argon AI—we’ve raised a $5.5 million seed round led by @CrosslinkCap and @WireframeVC , with support from @ycombinator , @pioneer_fund , and industry operators. Grateful to our customers for their trust and our investors @ThePhilBoyer, @harsh1,…
Proud to see portco @PhytoformLabs team up with @corteva to deploy AI‑driven gene editing on corn—fine‑tuning two native genes for disease resilience without GMOs. Another milestone pushing biotech from lab to field 🌍🌽 agfundernews.com/phytoform-and-…
“Our mission isn't just to uncover nature's chemistry, it's to translate these discoveries into treatments that could change lives today.” Enveda’s founder @viswacolluru spoke with @BBC about how life’s chemistry is a critical source of new medicines in #TheNextFrontier series.
“Our mission isn't just to uncover nature's chemistry, it's to translate these discoveries into treatments that could change lives today.” Enveda’s founder @viswacolluru spoke with @BBC about how life’s chemistry is a critical source of new medicines in #TheNextFrontier series.
On the cover… The Great Unknown: Chemistry’s Untapped Frontier in Understanding Life Behind every groundbreaking biological discovery lies a hidden chemical dance—millions of unseen reactions occurring every second. Our research published in @GENBiotechJrnl spotlights…
Looking for cracked entrepreneurial devs to join us in building the world's first "Async AI Software Engineer" DMs open :)
More than a clinical milestone – this marks real momentum for our lead asset. Our first-in-class oral therapeutic, ENV-294, cleared a major Phase I milestone with favorable safety results and it's showing potential to transform care for #atopicdermatitis patients. Read more:…
Climate resilience is a new market being built in real time. At our #SFClimateWeek2025 panel on Engineering Global Resilience, leaders from Google, Gridware, Understory & Nephila shared challenges & new tech approaches to managing climate risk 👇 wireframevc.com/community/sf-c…
The US battery storage market will 10x by 2035. Without optimization, billions get left on the table. Portco @tybaenergy is the autopilot for batteries, ensuring assets sell power at peak value—turning volatility to profit. Read about their $13.9M Series A heatmap.news/climate-tech/t…
#Asthma affects >250M people worldwide and has seen no new meaningful drug approvals in over a decade. Today, Enveda is announcing that we are expanding our first-in-class lead asset, ENV-294 in asthma, along with a world-class Asthma Advisory Board. Read more here:…
The energy industry is facing unprecedented changes — rising #electricity demand, evolving markets, and a shifting political landscape. The road ahead is full of opportunities for #energystorage, but also new challenges. We share four predictions for 2025 bit.ly/42JPunB
We’re thrilled to introduce something special today… The inaugural issue of 𝗜𝗻-𝗩𝗲𝗱𝗮, a periodic collection of our thoughts and findings at the intersection of technology, science, and humanity. We believe sharing the stories, breakthroughs, and perspectives that shape…
What if you had a platform that can simultaneously discover new targets *and* leads at scale? Just how many molecules exist in the entire plant kingdom? Read on to find out in this inaugural edition of In-Veda from @lifeschemistry
What if you had a platform that can simultaneously discover new targets *and* leads at scale? Just how many molecules exist in the entire plant kingdom? Read on to find out in this inaugural edition of In-Veda from @lifeschemistry
Heating & cooling buildings is the largest energy cost in real estate. Geothermal HVAC solutions from Bedrock Energy will cut costs by 50% while reducing harmful emissions. Congrats to the team on raising a $12M Series A to scale across the U.S. 🏢 axios.com/pro/climate-de…
Exciting news: @lbernicker’s has been promoted to Partner at @WireframeVC! In 3 short years, she's made significant contributions through strategic investments and unwavering support. Read more: wireframevc.com/community/lily… #VCWins #WomenInVC
The Climate Compass report—co-authored by Wireframe’s @lbernicker—highlights a new wave of climate startups making an impact, incl. portfolio co’s Xcimer, @salientpredict, @caladan_bio, and @GridwareInc. Read the full report here: climatecompassreport.com/report
The human & financial toll of climate disasters? 1.6B lives & $2T (per @iccwbo). We must invest in resilience: 🚀 Faster disaster response (@NearSpaceLabs) ⚡️ Grid protection (@GridwareInc) 🌦️ Smarter forecasts (@salientpredict) learn more: wireframevc.com/community/inve…
Phytoform’s AI technology CRE.AI.TIVE can redesign plant DNA to futureproof our food supply. synbiobeta.com/read/ai-meets-… Our foundation plant genomic model, detailed in a paper published today on the pre-print platform BioRxiv biorxiv.org/content/10.110… #AI
Matt Eggers 🇺🇸�... @EggersMatt
8K Followers 1K Following Surfing the leading edge of #Climatetech since ‘06. Early-stage VC at @PreludeVC. YIMBY. Bike advocate. As a kid in rural Iowa, my phone # was just 4 digits.
Joshua Posamentier @posamentier
3K Followers 976 Following GP @CongruentVC investing in awesome companies that solve global climate problems plus a dad and husband and more: 🚴🍩⚛️🥖⛷🏄♂️☢️🎶🥁📷🍿
Craig Lawrence @clawrence
12K Followers 5K Following Investing in companies leading the energy transition @energyventures. Studied @texas_univ @Stanford. Worked @IDEO @Accel @SunEdison @SolarBridgeTech @SunPower
Harsh @harsh1
2K Followers 489 Following managing partner @wireframevc｜ex: founder, engineer, natsec investor｜husband & father｜india ‣ chicago ‣ sf
Sophie Purdom @SophiePurdom
11K Followers 2K Following investing in early stage 🌎 startups @planeteercap & writing about the future of @climatetech_vc
ian @IanRountree
12K Followers 3K Following I believe individuals can change the world and started @cantos to enable them.
Dimitry Gershenson �... @d_gershenson
5K Followers 4K Following Now on Bluesky: https://t.co/9TbZoppkoT Funding climate entrepreneurs @enduring_planet // Dir at @getecosafi
Viswa Colluru @viswacolluru
1K Followers 335 Following Founder & CEO @envedabio I Son, husband, and teammate I India ‣ US for PhD @UWMadison I Love solving hard problems with amazing people
nvo @nickvanosdol
8K Followers 998 Following energy tech enthusiast • short fiction enjoyooor • shooter of rinky dink film photos • sub for b2b sustainability musings here ⤵️ • ˚₊‧ ☾ ｡⋆ ꒰ა♥︎໒꒱ ⋆｡
Enveda @lifeschemistry
2K Followers 93 Following Engineering new drugs from nature with knowledge graphs, metabolomics, and ML
Janice Chen @janiceschen
4K Followers 400 Following Co-founder @mammothbiosci. PhD from @doudna_lab | @UCBerkeley MCB
VSC @VSCPR
3K Followers 4K Following We are a band of strategists, storytellers and data nerds obsessed with helping Davids crush a sea of Goliaths, through unfair amounts of awareness.
Solugen @solugen
5K Followers 294 Following Innovative chemical solutions for the toughest industrial challenges.
Ramez Naam @ramez
53K Followers 8K Following Climate and clean energy investor. Author of 5 books. Energy & Environment co-chair @SingularityU. Trying to build a better world.
Jonah Kallenbach @jonahkallenbach
797 Followers 2K Following On sabbatical. Previously founder & CEO @reverielabs, AB/SM in CS from @hseas.
Keegan Reynolds @KeeganReynolds7
955 Followers 1K Following Romans 12:12 | 25 🇺🇸 The People’s Government (Podcast):
Sychev Pavel @pavlitosy4
10K Followers 2K Following Founder @cryptonxyz & @OpenAcademyAI 📚 Build EdTech in WEB3 🥇 KOL 600k+ Binance Awards 2022, Bitget Awards 2024 | DM is open 🤝
Mario Bollini @mario_bollini
259 Followers 1K Following Atlas product lead @bostondynamics. Views my own.
Arkim AI @Arkim_AI
19 Followers 112 Following AI tools for the next generation of equipment maintenance and management. Partnered with NVIDIA's Inception Program and Databricks Launch Program
Sara Rinehart @sarafknrinehart
66 Followers 349 Following Founder of Beauty Genome ✦ Writer of Loud Girls Finish First ✦ Startup confessions, beauty heresies & woo-woo tech spells.
AR_Shane54 @Artshane54
164 Followers 885 Following Founder-Shane Solutions LLC Inventor of Neuratherm Power Systems
EzMarkett @EzMarkettt
7 Followers 191 Following End-to-End podcast production for VCs, B2B teams & Tech founders.
Georg "Arch" Bool @ASIshallcome
12 Followers 350 Following Innovator in Artificial Intelligence Field Advancing modern theories and AI architectures LOOKING FOR AI ANGEL INVESTORS Alignment | Superintelligence
James L H Bartlett @jameslhbartlett
81K Followers 48K Following I enjoy business, innovation, life-long learning & to #ChangeTheWorld to help others. Entrepreneur, interim CxO, investor, adventurer, thinker & do-er. NO DMs!
Sammy Kalejaiye @CoachKalejaiye
2K Followers 3K Following Assistant Coach, @LincolnMBB | Player Development • Culture • System Builder Founder @kanext360 | Live Evaluation + Team Infrastructure
Marco Pascha @34marcopascha
323 Followers 7K Following Passionate about EdTech& AI.Focused on innovative learning solutions and emerging tech.Sharing projects and insights to help shape the future together...
capitalgambit @CapitalgambitAi
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Anchor House @anchor_house
8 Followers 259 Following if you have the boat. or have friend or connection have the boat. yacht. show video to them they can understand this product instainly.
Dagfinn Holme @finny12_dh3501
73 Followers 1K Following Inventor, Founder, record breaking LCOE and ROI for solar energy with https://t.co/3eH8i6CFkf
Chai @Chainames
376 Followers 7K Following
Michael Fenn @mbfennjr
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Falahuddin @Falahuddin23
228 Followers 7K Following Crypto, Metaverse, Web3, Nexus, AI, computer scientist, IT system integrator turned digital angel investor #Sandbox 8x #Solana 22x #OM 6x
detainment @detainment76920
40 Followers 4K Following
Barsar @Barsar9070634
12 Followers 224 Following
Arguirjip @Arguirjip3276
10 Followers 221 Following
Evatar.ai @Evatar_ai
21 Followers 184 Following AI agents that automate the full content lifecycle: create → post → engage → improve
SEBASTIAN MONSALVE @SEBASTIANM64334
295 Followers 7K Following
ecoCFO @ecoCFOllc
144 Followers 328 Following ecoCFO provides accounting, financial modeling, CFO advisory, grants management, and capital markets services for startups and nonprofits in the climate sector.
Bitwala @Bitwala
14K Followers 2K Following OWN YOUR FUTURE. LIVE ON CRYPTO. Grow your wealth by managing bitcoin, ether & euros securely in one app. Spend instantly with your bank account & Visa card.
Proven @getproven
83 Followers 1K Following A platform to create communities of companies you trust from Perk Management to Vendor Organization.
ceejoy @CeejoyWjoy11683
2 Followers 47 Following
0xTSV @0xTSV
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Austin Hill @austinhill
18K Followers 12K Following Cofounder @ Machine Phase Systems | Solving humanity’s biggest challenges one atom at a time. x Blockstream, ZeroKnowledgeSystems, InJoy
National Grid Partner... @ngpartners_
2K Followers 2K Following National Grid Partners is the venture investment and innovation arm of National Grid plc. #NGPartners #ThePotentialOfEnergy
Mer @Telltoyfu
1 Followers 937 Following
Meg McNulty @meggmcnulty
344 Followers 1K Following building the future of hardware | alumna @stanford @sandboxaq | deeptech, edge compute + caffeine | founder @ stealth
Quattau @quattau68802
31 Followers 961 Following
Phytoform @PhytoformLabs
526 Followers 575 Following Making agriculture sustainable & unlocking the genetic potential of plants.
LucasArielFer @LucasAr16078596
89 Followers 981 Following
Nicholas Marquardt @NickAMarquardt
48 Followers 246 Following
Peter J @pjchicago88
145 Followers 869 Following work in food. love talking about finance, food ops, cpg, and fast casual.
Logan DeSouza @logan_desouza
179 Followers 743 Following M&A, VC, and Emerging Company Attorney @KOlawyers | No Legal/Investment Advice | Former @PaulWeissLLP | @dukelaw | Boulder, CO
PandoraMotley @481l3mVg6F2ndT6
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Swamini Khanvilkar @swamini_
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Josh Breite @joshbreite
695 Followers 5K Following Engineer @joinpogo | Prev Co-founder @_joinfire | @KERNEL0x block 7 | @joinatomic | @joinpogo | @northwesternu
All Raise @AllRaise
26K Followers 3K Following Move Money. Shift Power. Change Culture. When the venture capital ecosystem evolves, women and nonbinary investors and founders succeed.
Shen-Tien Chi @shentienchi
235 Followers 2K Following Venture investor @ Novare Ventures Labs Startup and venture capital newsletter: https://t.co/HPAcbAQo3c
Tommy Leep @leepnet
10K Followers 768 Following Investing via Jetstream, the pre-seed fund for accelerating prosperity
Matt Eggers 🇺🇸�... @EggersMatt
8K Followers 1K Following Surfing the leading edge of #Climatetech since ‘06. Early-stage VC at @PreludeVC. YIMBY. Bike advocate. As a kid in rural Iowa, my phone # was just 4 digits.
Joshua Posamentier @posamentier
3K Followers 976 Following GP @CongruentVC investing in awesome companies that solve global climate problems plus a dad and husband and more: 🚴🍩⚛️🥖⛷🏄♂️☢️🎶🥁📷🍿
Harsh @harsh1
2K Followers 489 Following managing partner @wireframevc｜ex: founder, engineer, natsec investor｜husband & father｜india ‣ chicago ‣ sf
Nicole Kelner @NicoleKelner
18K Followers 1K Following Just trying to be the Leslie Knope of climate. Making climate art 🎨 Author of Electrify Everything: The Clean Energy Coloring Book
Sophie Purdom @SophiePurdom
11K Followers 2K Following investing in early stage 🌎 startups @planeteercap & writing about the future of @climatetech_vc
ian @IanRountree
12K Followers 3K Following I believe individuals can change the world and started @cantos to enable them.
Viswa Colluru @viswacolluru
1K Followers 335 Following Founder & CEO @envedabio I Son, husband, and teammate I India ‣ US for PhD @UWMadison I Love solving hard problems with amazing people
nvo @nickvanosdol
8K Followers 998 Following energy tech enthusiast • short fiction enjoyooor • shooter of rinky dink film photos • sub for b2b sustainability musings here ⤵️ • ˚₊‧ ☾ ｡⋆ ꒰ა♥︎໒꒱ ⋆｡
Enveda @lifeschemistry
2K Followers 93 Following Engineering new drugs from nature with knowledge graphs, metabolomics, and ML
Janice Chen @janiceschen
4K Followers 400 Following Co-founder @mammothbiosci. PhD from @doudna_lab | @UCBerkeley MCB
Chris Gibson @RecursionChris
8K Followers 1K Following Father/Husband/Scientist/Co-Founder & CEO $RXRX, “OG of TechBio,” “gentle giant,” Boards: @cellinobio @sltrib @biohiveutah - TechBio/cars/musings/typos/opinions
Ramez Naam @ramez
53K Followers 8K Following Climate and clean energy investor. Author of 5 books. Energy & Environment co-chair @SingularityU. Trying to build a better world.
Jonah Kallenbach @jonahkallenbach
797 Followers 2K Following On sabbatical. Previously founder & CEO @reverielabs, AB/SM in CS from @hseas.
National Grid Partner... @ngpartners_
2K Followers 2K Following National Grid Partners is the venture investment and innovation arm of National Grid plc. #NGPartners #ThePotentialOfEnergy
Absolute Climate @absclimate
63 Followers 37 Following Absolute Climate builds MRV that matches project claims to climate impacts
Samy Danesh ∞ @DaneshSamy
441 Followers 661 Following building AI Co-Workers for drug development @ai_argon (YC)
Cyrus Jia @theCyrusJia
163 Followers 189 Following Building @ai_argon (YC W24) // AI for Pharma Intelligence // prev @bridgewater @gopuff @USC
Caladan Bio @caladan_bio
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Applied Carbon @AppliedcarbonCo
117 Followers 40 Following Developer of mobile biochar production systems for commercial agriculture. Top 20 Finalist @Xprize Carbon Removal Competition
Inevitable podcast @inevitablemcj
7K Followers 620 Following A weekly podcast about the inevitable impacts of climate change, ft. experts & entrepreneurs rewriting industries for the future. Fka 'My Climate Journey.'
Activate @activatefellows
3K Followers 769 Following Accelerating scientific discoveries to drive innovation.
Pasture Bio @PastureBio
21 Followers 1 Following Vaccinating cattle for beef and dairy with less methane. Join us at https://t.co/IKyaJvippg
Gigascale @gigascale
587 Followers 2 Following We are Gigascale Capital, a new kind of VC firm supporting the next generation of companies solving the climate crisis.
Mike Schroepfer @schrep
100K Followers 271 Following founder @Gigascale, Sr Fellow/fmr CTO @Meta, founder @AdditionalVent. Let’s go build!
Nikita S @singareddynm
27K Followers 2K Following https://t.co/2YIw27nyy9 👩🏾💻 days: building Fortuna Health, nights: exploring spaceship earth
Founders You Should K... @foundersysk
976 Followers 25 Following We host a monthly IRL startup showcase in SF to help the best engineers connect with breakout startups
Cantos @cantos
5K Followers 133 Following A 1st-round venture capital firm in pursuit of legends in the making solving the world's biggest problems
Climate Capital @climatecap
902 Followers 151 Following Backing emissions reduction & adaption since 2015. Join us: https://t.co/tzTDEuTqdw Substack - https://t.co/8OpE2nfNld
Shomik Dutta @shomikdutta
3K Followers 2K Following Co-Founder & Managing Partner @overture_VC. Co-Founder @highergroundlab. Obama ‘08 & White House. Top 5000 under 500. McDonald's Genius Award.
The OpenAir Collectiv... @openaircollect
3K Followers 1K Following Removing carbon from the atmosphere. Together. A global volunteer network advancing carbon removal via open-source policy, R&D, and communications missions.
Andrew Wang @ndrewwang
5K Followers 5K Following plugging batteries into the grid @StandPotential & @ActivateFellows + @Breakthrough. go read @IntercalationSt 🔋🚂
sundeep ahuja @sunrock
3K Followers 854 Following Investor: 200+ climate startups (https://t.co/AZFmS6vjD4). Founder: 3 startups + 2 VCs + 1 climate non-profit. Author: Haline (4.2 star cli-fi novel).
Arvind Gupta @arvndgpta
4K Followers 728 Following Partner @Mayfieldfund, Author - Decoding the World. Founder & Venture Advisor @indbio I invest in human and planetary health.
NextView @NextViewVC
10K Followers 770 Following High-conviction, hands-on seed investors. Championing founders who are redesigning the Everyday Economy.
Zivian Health @ZivianHealth
14 Followers 2 Following Zivian Health is a compliance and quality platform backed by a nationwide network of physicians. We help scale advanced practice provider (NPs/PAs) workforces.
The Ad Hoc Group @adhocgroupinc
95 Followers 74 Following We work with climate tech startups, investors, and mission-aligned corporations. Sign up for our monthly newsletter on climate tech + policy at the link below.
August Allen @augallen
206 Followers 323 Following
Peter Minor @PeterMinor
769 Followers 251 Following
Tembo @tembo
5K Followers 6 Following background agents for technical teams — ask better, build faster
Julian Smith @JulianSmith924
163 Followers 328 Following
Erzsi Sousa @erzsisousa
424 Followers 461 Following Outdoors x climate x brand x puppies. Board of @terrasetclimate. Also x-@stripe @google @microsoft.
. @username3829472
4K Followers 3K Following
New Energy Nexus @NewEnergyNexus
4K Followers 1K Following The world's leading ecosystem of funds and accelerators supporting diverse clean energy entrepreneurs to thrive.
DIMENSION @_DimensionCap
2K Followers 21 Following A first-of-its-kind firm partnering with founders at the interface of technology and life sciences to transform the trajectory of life on earth
ry @rywalker
10K Followers 5K Following ceo @tembo • prev founder/ceo @astronomerio (yes, that astronomer) • I follow back all startup people who post, and unfollow unfollowers
Donnie Flood @floodfx
685 Followers 1K Following 👋Co-founder @canopyclimate - climate benefits! 🧑💻Author of @liveviewjs⏩ Former: @homeboundhomes, @GuildEducation, @linkedin, Bizo, Admob.
Pablo Lubroth @pablolubroth
2K Followers 679 Following vp @ enveda | co-founder https://t.co/JaCPdwlEuK | biochem eng, neuro @ucl @cambridge_uni
BIOS @bios_community
15K Followers 2K Following Uniting the Life Science Ecosystem In #PatientImpact — Highlighting Industry Leaders Shaping The Future Of Medicine✨By: @alixventures
Alix Ventures @AlixVentures
1K Followers 1K Following Supporting Life Sciences Startups Building Platforms Shaping The Future Of Medicine✨ — 🚫 Views expressed by guests are their own & not represent @AlixVentures
Chris Ghadban @ceghadban
961 Followers 1K Following biotech startups, VC @TVC @1bio | #FirstGen 🇺🇲 & 👨🎓 | MS/MBA @Wharton @Tufts | Boston/SF/Philly/NY/ - opinions my own & subject to change
Tom Quigley @TomMQuigley
1K Followers 1K Following Conservationist ➡️ startup operator ➡️ investing in biodiversity. @superorganismvc 🌎
Canopy @canopyclimate
83 Followers 5 Following Working with corporations and governments to remove 1+ gigaton of emissions from household energy use.
Neal Dikeman @nealdikeman
955 Followers 616 Following Early stage cleantech and climate venture capitalist at @EnergyVentures, 7x startup founder, @LPTexas Nominee for US Senate, 2018.
Salient @salientpredict
199 Followers 141 Following The new standard in 2-to-52 week weather analytics.
Chad Conway @chadwickconway
694 Followers 548 Following Tweets are my own. #electrification geek. #induction #heatpumps #solar #evs #batteries Founding team of @Span_IO, 2020 @Energy_Leaders, @tesla alum
microplastics enjoyer @gbennett41
772 Followers 2K Following Climate tech investor. Views are my own.
Heidi Krauel Patel @HeidiPatelSF
3K Followers 1K Following Managing Partner @RethinkImpact. Lecturer @StanfordGSB on Investing for Good. Opinions=my own.Trends for United States
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